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Journal of Geriatric Cardiology 2020年第9期17卷 574-579页

作者： Fritz Kather Miralem Hadzic Teresa Hehle Sarah Eichler Julia klein Heinz Völler Annett Salzwedel Department of Rehabilitation Medicine University of PotsdamFaculty of Health Sciences BrandenburgGermany Klinik am See Rehabilitation Center for Internal MedicineRüdersdorfGermany

Malnutrition is described as a state of insufficient intake of energy,protein and other nutrients leading to changes in body composition(weight loss,reduced fat-free mass)as well as adverse functional and clinical outcomes.[1]Depending on the assessments and definition used,the prevalence in older patients ranges between 12%in communitydwelling adults to 60%of patients in geriatric care facilities.[2–5]Older populations are at high risk of nutritional deficiencies because of risk factors such as multimorbidity,polypharmacy,cognitive and physical decline,poor appetite,depressive syndromes and socioeconomic changes.[4,6].

关键词： Cardiac rehabilitation Malnutrition Octogenarians Test-retest reliability

What does the “arrow of time” stand for?

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Natural Science 2010年第3期2卷 212-219页

作者： Etienne klein 不详

One hundred and thirty years after the work of Ludwig Boltzmann on the interpretation of the irreversibility of physical phenomena, and one century after Einstein's formulation of Special Relativity, we are still not sure what we mean when we talk of “time” or “arrow of time”. We shall try to show that one source of this difficulty is our tendency to confuse, at least verbally, time and becoming, i.e. the course of time and the arrow of time, two concepts that the formalisms of modern physics are careful to distinguish. The course of time is represented by a time line that leads us to define time as the producer of duration. It is customary to place on this time line a small arrow that, ironically, must not be confused with the “arrow of time”. This small arrow is only there to indicate that the course of time is oriented, has a well-defined direction, even if this direction is arbitrary. The arrow of time, on the other hand, indicates the possibility for physical systems to experience, over the course of time, changes or transforma-tions that prevent them from returning to their initial state forever. Contrary to what the ex-pression “arrow of time” suggests, it is there-fore not a property of time itself but a property of certain physical phenomena whose dynamic is irreversible. By its very definition, the arrow of time presupposes the existence of a well- established course of time within which – in addition – certain phenomena have their own temporal orientation. We think that it is worth-while to emphasize the difference between sev-eral issues traditionally subsumed under the label “the problem of the direction of time”. If the expressions “course of time”, “direction of time” and “arrow of time” were better defined, systematically distinguished from one another and always used in their strictest sense, the debate about time, irreversibility and becoming in physics would become clearer.

关键词： Time Time’S Arrow Temporal Asymmetry Principle of Causality Irreversibility

Local Identity in Palestine in the Late 19th and Early 20th Centuries--- Challenging Dominant Methodologies

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International Relations and Diplomacy 2014年第8期2卷 533-542页

作者： Menachem klein Bar Ilan University Ramat Gan Israel

In-hospital outcomes of transapical versus surgical aortic valve replacement: from the U.S. national inpatient sample

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Journal of Geriatric Cardiology 2021年第9期18卷 702-710页

作者： Ashraf Abugroun Osama Hallak Ahmed Taha Alejandro Sanchez-Nadales Saria Awadalla Hussein Daoud Efehi Igbinomwanhia Lloyd W klein Department of Internal Medicine Medical College of Wisconsin(MCW)WIUSA Division of Cardiology Ketter-ing Medical CenterOHUSA Department of Internal Medicine School of MedicineIndiana UniversityIndianapolisIndianaUSA Department of Cardiovascular Disease Cleveland Clinic FloridaFLUSA Division of Epidemiology&Biostatistics University of Illinois-ChicagoILUSA Division of Cardiology Creighton UniversityNEUSA Department of Cardiology Case Western Reserve University(MetroHealth)OHUSA University of California San Francisco(UCSF)San FranciscoCAUSA

OBJECTIVE To compare the outcomes of transapical transcatheter aortic valve replacement(TA-TAVR)and surgical aortic valve replacement(SAVR)using a large US population *** The *** Inpatient Sample was queried for all patients who underwent TA-TAVR or SAVR during the *** primary outcome was all-cause in-hospital *** outcomes were in-hospital stroke,pericardiocentesis,pacemaker insertion,mechanical ventilation,vascular complications,major bleeding,acute kidney injury,length of stay,and cost of *** were modeled using multi-variable logistic regression for binary outcomes and generalized linear models for continuous *** A total of 1560 TA-TAVR and 44,280 SAVR patients were *** who underwent TA-TAVR were older and *** to SAVR,TA-TAVR correlated with a higher mortality(4.5%vs.2.7%,effect size(SMD)=0.1)and higher periprocedural *** multivariable analysis,both TA-TAVR and SAVR had a similar adjusted risk for in-hospital ***-TAVR correlated with lower odds of bleeding with(adjusted OR(aOR)=0.26;95%CI:0.18-0.38;P<0.001),and a shorter length of stay(adjusted mean ratio(aMR)=0.77;95%CI:0.69-0.84;P<0.001),but higher cost(aMR=1.18;95%CI:1.10-1.28;P<0.001).No significant differences in other study *** subgroup analysis,TA-TAVR in patients with chronic lung disease had higher odds for mortality(aOR=3.11;95%CI:1.37-7.08;P=0.007).CONCLUSION The risk-adjusted analysis showed that TA-TAVR has no advantage over SAVR except for patients with chronic lung disease where TA-TAVR has higher mortality.

关键词： logistic In-hospital outcomes of transapical versus surgical aortic valve replacement from the U.S national inpatient sample

The Insphere of a Tetrahedron

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Applied Mathematics 2020年第7期11卷 601-612页

作者： Peter Paul klein Computing Center University of Technology Clausthal Clausthal-Zellerfeld Germany

A contiguous derivation of radius and center of the insphere of a general tetrahedron is given. Therefore a linear system is derived. After a transformation of it the calculation of radius and center can be separated from each other. The remaining linear system for the center of the insphere can be solved after discovering the inverse of the corresponding coefficient matrix. This procedure can also be applied in the planar case to determine radius and center of the incircle of a triangle.

关键词： Corkscrew Rule Hesse Normal Form Decomposed Linear System Block Upper Triangular Form of Coefficient Matrix Cofactor Matrix

Largest dinosaur tracksite in China (Cretaceous, Zhaojue area, Sichuan Province): On the verge of destruction

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Geoscience Frontiers 2021年第5期12卷 124-137页

作者： Lida Xing Martin G.Lockley Hendrik klein W.Scott Persons IV Guangzhao Peng Yong Ye Miaoyan Wang State Key Laboratory of Biogeology and Environmental Geology China University of GeosciencesBeijing 100083China School of the Earth Sciences and Resources China University of GeosciencesBeijing 100083China Dinosaur Trackers Research Group University of ColoradoDenver 80217USA Saurierwelt Paläontologisches Museum Alte Richt 7D-92318 NeumarktGermany Mace Brown Museum of Natural History Department of Geology and Environmental GeosciencesCollege of CharlestonCharleston 29401USA Zigong Dinosaur Museum ZigongSichuan ProvinceChina

The Zhaojue(ZJ)tracksites represent multiple steeply-inclined,track-bearing exposures in the clastic Feitianshan Formation of Sichuan Province that have been sequentially,excavated,mapped,expanded and destroyed,by quarrying,erosion or collapse,for almost three *** quarried area extends for more almost 1.0 km from north to south and-0.5 km from east to *** important track-bearing surfaces have been identified and identified as ZJ-Ⅰ,ZJ-Ⅱ,ZJ-ⅡN and ZJ-Ⅲ,some of which are newly exposed surfaces or expanded surfaces that were previously partially *** represent surfaces lost since they were first reported in papers published in *** ZJ-Ⅱ site represents a hugely expanded continuation of a much smaller track-bearing surface described in *** was mapped using drone technology,and now represents the largest tracksite in China,with a minimum count of 933 recognizable tracks,and the longest recorded sauropod and ornithopod trackways from China(-80 m and-52 m respectively),which also reveal a pronounced change in the direction of trackmaker *** ZJ-Ⅱ surface represents the best Zhaojue paleo-census sample giving a count of 68 individuals from 61 trackways(37 ornithopod,10 theropod,14 sauropod)and isolated tracks(representing 7 individuals).Thus,ornithopods(both large and small trackmakers)represent-54%of the total number of *** smaller ZJ-Ⅲ surface was mapped using traditional methods,and reveals at least 6 ornithopod-and 4 theropod *** the ZJ-Ⅱ and ZJ-Ⅲ surfaces reveal parallel ornithopod trackways suggestive of social or gregarious *** combined data from all four Zhaojue surfaces reveal a total of 1928 tracks,and include a few previously reported pterosaurs and theropod swim *** Zhaojue quarry complex provide a good example of multiple track-bearing sites(surfaces)that require long term study and monitoring to extract as much trackway data as possible before in situ physical evidence is lost.

关键词： Feitianshan Formation Onithopod Teropod Suropod

Energy and spectral analysis of confined solar flares from radio and X-ray observations

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Research in Astronomy and Astrophysics 2021年第11期21卷 35-46页

作者： Cheng-Ming Tan Karl Ludwig klein Yi-Hua Yan Satoshi Masuda Bao-Lin Tan Jing Huang Guo-Wu Yuan CAS Key Laboratory of Solar Activity National Astronomical Observatories of Chinese Academy of SciencesBeijing 100101China School of Astronomy and Space Sciences University of Chinese Academy of SciencesBeijing 100049China Observatoire de Paris LESIA&Station de radioastronomie de Nanc¸ayUniv.PSLCNRSSorbonne Univ.Univ.de ParisUniv.d’Orl´eans5 place Jules JanssenF-92190 MeudonFrance Institute for Space-Earth Environmental Research Nagoya UniversityNagoya 464-8601Japan School of Information Science and Engineering Yunnan UniversityKunming 650091China

The energy and spectral shape of radio bursts may help us understand the generation mechanism of solar eruptions,including solar flares,coronal mass ejections,eruptive filaments,and various scales of *** different kinds of flares may have different characteristics of energy and spectral *** this work,we selected 10 mostly confined flare events during October 2014 to investigate their overall spectral behaviour and the energy emitted in microwaves by using radio observations from microwaves to interplanetary radio waves,and X-ray observations of GOES,RHESSI,and Fermi/*** found that:all the confined flare events were associated with a microwave continuum burst extending to frequencies of9.4~15.4 GHz,and the peak frequencies of all confined flare events are higher than 4.995 GHz and lower than or equal to 17 *** median value is around 9 *** microwave burst energy(or nuence)and the peak frequency are found to provide useful criteria to estimate the power of solar *** observations imply that the magnetic field in confined flares tends to be stronger than that in 412 flares studied by Nita et al.(2004).All 10 events studied did not produce detectable hard X-rays with energies above~300 keV indicating the lack of efficient acceleration of electrons to high energies in the confined flares.

关键词： Sun:solar flare Sun:radio burst Sun:energy Sun:spectral

Advanced protection against environmental degradation of silver mirror stacks for space application

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Journal of Materials Science & Technology 2021年第5期64卷 1-9页

作者： Rajendra Kurapati Vincent Maurice Antoine Seyeux Lorena H.klein Dimitri Mercier Gregory Chauveau Catherine Grees-Besset Loic Berthod Philippe Marcus PSL Research University CNRS-Chimie ParisTechInstitut De Recherche De Chimie ParisPhysical Chemistry of Surfaces Group11 Rue Pierre Et Marie Curie75005 ParisFrance CILAS MARSEILLE 600 Avenue De La Roche FourcadePole ALPHA Sud-Saint Mitre13400 AubagneFrance CNES Sous-direction Assurance QualitéService TechnologiesMatériaux Et Procédés18 AvenueÉdouard Belin31401 ToulouseFrance

Protection of silver mirror stacks from environmental degradation before launching is crucial for space ***,we report a comparative study of the advanced protection of silver mirror stacks for space telescopes provided by SiO_(2)and Al_(2)O_(3)coatings in conditions of accelerated aging by *** model silver stack samples were deposited by cathodic magnetron sputtering on a reference silica substrate for optical applications and a surface-pretreated SiC *** aging was per-formed in dry and more severe wet *** micrographic observations,surface and interface analysis by Time-of Flight Secondary Ion Mass Spectrometry(ToF-SIMS)and reflectivity measurements were combined to comparatively study the effects of *** results show a lower kinetics of degradation by accelerated aging of the stacks protected by the alumina coating in comparable test conditions.

关键词： Mirror layers Protection Layers Silver Atmospheric corrosion Accelerated aging Surface analysis Space applications

Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles(Microtus ochrogaster)

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International Journal of Oral Science 2015年第1期7卷 23-26页

作者： Andrew H Jheon Michaela Prochazkova Michael Sherman Devanand S Manoli Nirao M Shah Lawrence Carbone Ophir klein Department of Orofacial Sciences and Program in Craniofacial and Mesenchymal Biology University of California San Francisco (UCSF) Department of Anthropology and Human Genetics Faculty of Science Charles University in Prague Laboratory Animal Resource Center UCSF Department of Psychiatry UCSF Department of Anatomy UCSF

Continuously growing incisors are common to all rodents, which include the Microtus genus of voles. However, unlike many rodents, voles also possess continuously growing molars. Here, we report spontaneous molar defects in a population of Prairie voles （Microtus ochrogaster）. We identified bilateral protuberances on the ventral surface of the mandible in several voles in our colony. In some cases, the protuberances broke through the cortical bone. The mandibular molars became exposed and infected, and the maxillary molars entered the cranial vault. Visualisation upon soft tissue removal and microcomputed tomography （microCT） analyses confirmed that the protuberances were caused by the overgrowth of the apical ends of the molar teeth. We speculate that the unrestricted growth of the molars was due to the misregulation of the molar dental stem cell niche. Further study of this molar phenotype may yield additional insight into stem cell regulation and the evolution and development of continuously growing teeth.

关键词： continuously growing teeth molar phenotype mutation stem cell regulation voles

An inflammatory subtype of pancreatic ductal adenocarcinoma is associated with poor prognosis and increased perioperative mortality

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Journal of Pancreatology 2019年第3期2卷 107-112页

作者： Benzing Christian klein Fritz Pelzer Uwe Sinn Marianne Pratschke Johann Bahra Marcus Campus Charité-Mitte and Campus Virchow Klinikum Charité-Universitätsmedizin BerlinBerlinGermany Department of Hematology Oncology and Tumor ImmunologyCharité-Universitätsmedizin BerlinBerlinGermany

Pancreatic ductal adenocarcinoma(PDAC)is a malignancy characterized by an aggressive tumor *** present analysis seeks to identify and analyze a cohort that meets criteria for"inflammatory"PDAC(IPDAC).All patients who underwent a curative resection for PDAC at our institution between 1989 and 2015 were included in the retrospective *** with histological proven adenocarcinoma and elevated C-reactive protein(CRP)(≥6 mg/L)serum concentrations,but no other suspicion of infection were *** provide a matched control group with normal CRP serum levels from the same patient ***-six(6.8%)of 532 patients meet our criteria for an IPDAC group ***-hospital(30 days)mortality was 13.9%in the IPDAC group vs 0%in the control group(P=.020).Median follow-up was 183.8 months(standard deviation[SD]=53.3,range 14.3-285.4).Median overall survival was 8.5 months(SD=16.8,range 0.3-89.6)in the IPDAC group and 24.8 months(SD=19.4,range 0.7-80.4)in the control group(P=.002).Patients indicating an IPDAC in our cohort had a significantly and clinical meaningful decreased overall survival and a higher perioperative morbidity and mortality.

关键词： Cholangitis CRP Inflammatory carcinoma PDAC