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International Journal of Ophthalmology(English edition) 2023年第3期16卷 468-469页

作者： kin-man tam Iat-Fan Lai Department of Ophthalmic Center Kiang Wu HospitalMacao 999078China

Dear Editor,Erlotinib is an epidermal growth factor receptor (EGFR)inhibitor used in the treatment of non-small cell lung *** side effects of erlotinib include rash and diarrhea,while eyelash trichomegaly and hair dis... 详细信息

关键词： diarrhea treatment ulcer

Ignition Pattern Analysis for Automotive Engine Trouble Diagnosis Using Wavelet Packet Transform and Support Vector Machines

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Chinese Journal of Mechanical Engineering 2011年第5期24卷 870-878页

作者： VONG Chi-man WONG Pak-kin tam Lap-mou ZHANG Zaiyong Department of Computer and Information Science Faculty of Science and Technology University of Macao Macao China Department of Electromechanical Engineering Faculty of Science and Technology University of Macao Macao China

Engine spark ignition is an important source for diagnosis of engine *** on the waveform of the ignition pattern,a mechanic can guess what may be the potential malfunctioning parts of an engine with his/her experience and ***,this manual diagnostic method is imprecise because many spark ignition patterns are very ***,a diagnosis needs many trials to identify the malfunctioning *** the mechanic needs to disassemble and assemble the engine parts for *** tackle this problem,an intelligent diagnosis system was established based on ignition ***,the captured patterns were normalized and *** wavelet packet transform（WPT） was employed to extract the representative features of the ignition ***,a classification system was constructed by using multi-class support vector machines（SVM） and the extracted *** classification system can intelligently classify the most likely engine fault so as to reduce the number of diagnosis *** results show that SVM produces higher diagnosis accuracy than the traditional multilayer feedforward neural *** is the first trial on the combination of WPT and SVM to analyze ignition patterns and diagnose automotive engines.

关键词： automotive engine ignition pattern diagnosis pattern classification wavelet packet transform support vector machines.

Pathological mechanisms and therapeutic strategies for Alzheimer's disease

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Neural Regeneration Research 2022年第3期17卷 543-549页

作者： Yaojun Ju kin Yip tam Faculty of Health Sciences University of MacaoAvenida de UniversidadeTaipaMacao Special Adiministrative RegionChina

Alzheimer's disease is a rather complex neurodegenerative disease,which is attributed to a combination of multiple *** the many pathological pathways,synaptic dysfunctions,such as synapses loss and deficits in synaptic plasticity,were thought to be strongly associated with cognitive *** deficiencies in various sorts of neurotransmissions are responsible for the multifarious neurodegenerative symptoms in Alzheimer's disease,for example,the cholinergic and glutamatergic deficits for cognitive decline,the excitatory and inhibitory neurotransmission dyshomeostasis for synaptic plasticity deficits and epileptiform symptoms,and the monoamine neurotransmission for neuropsychiatric *** cascade hypothesis is the most popular pathological theory to explain Alzheimer's disease pathogenesis and attracts considerable *** lines of genetic and pathological evidence support the predominant role of amyloid beta in Alzheimer's disease *** tangles assembled by microtubule-associated protein tau are other important histopathological characteristics in Alzheimer's disease *** of tau toxicity was proved to lead to neuron damage,neuroinflammation and oxidative stress in *** is the main risk factor of neurodegenerative diseases,and is associated with inflammation,oxidative stress,reduced metabolism,endocrine insufficiencies and organ *** aging related risk factors were also proved to be some of the risk factors contributing to Alzheimer's *** Alzheimer's disease drug development,many good therapeutic strategies have been investigated in clinical ***,complex mechanism of Alzheimer's disease and the interplay among different pathological factors call for the come out of allpowerful therapies with multiple curing *** review seeks to summarize some of the representative treatments targeting different pathological pathways currently under clinical ***

关键词： Alzheimer's disease pathological pathways drug development multiple pathologies

DYNAMIC MODEL AND SIMULATION OF A NOVEL ELECTRO-HYDRAULIC FULLY VARIABLE VALVE SYSTEM FOR FOUR-STROKE AUTOMOTIVE ENGINES

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Chinese Journal of Mechanical Engineering 2007年第5期20卷 80-86页

作者： WONG Pak-kin tam Lap-mou LI Ke Department of Electromechanical Engineering Faculty of Science and Technology University of Macao Macao China

In modem four-stroke engine technology, variable valve timing and lift control offers potential benefits for making a high-performance engine. A novel electro-hydraulic fully variable valve train for four-stroke automotive engines is introduced. The construction of the nonlinear mathematic model of the valve train system and its dynamic analysis are also presented. Experimental and simulation results show that the novel electro-hydraulic valve train can achieve fully variable valve timing and lift control. Consequently the engine performance on different loads and speeds will be significantly increased. The technology also permits the elimination of the traditional throttle valve in the gasoline engines and increases engine design flexibility.

关键词： Fully variable engine valve train Dynamic model Simulation

A Local Deviation Constraint Based Non-Rigid Structure From Motion Approach

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IEEE/CAA Journal of Automatica Sinica 2020年第5期7卷 1455-1464页

作者： Xia Chen Zhan-Li Sun kin-man Lam Zhigang Zeng School of Electrical Engineering and Automation Anhui UniversityHefei 230601China Department of Electronic and Information Engineering The Hong Kong Polytechnic UniversityHong Kong 999077China School of Artificial Intelligence and Automation Huazhong University of Science and TechnologyWuhan 430074China IEEE

In many traditional non-rigid structure from motion(NRSFM)approaches,the estimation results of part feature points may significantly deviate from their true values because only the overall estimation error is considered in their *** at solving this issue,a local deviation-constrained-based column-space-fitting approach is proposed in this paper to alleviate estimation *** our work,an effective model is first constructed with two terms:the overall estimation error,which is computed by a linear subspace representation,and a constraint term,which is based on the variance of the reconstruction error for each ***,an augmented Lagrange multipliers(ALM)iterative algorithm is presented to optimize the proposed ***,a convergence analysis is performed with three steps for the optimization *** both the overall estimation error and the local deviation are utilized,the proposed method can achieve a good estimation performance and a relatively uniform estimation error distribution for different feature *** results on several widely used synthetic sequences and real sequences demonstrate the effectiveness and feasibility of the proposed algorithm.

关键词： Augmented Lagrange multipliers(ALM) columnspacefitting non-rigid structure from motion(NRSFM)

Complexity scalable control algorithm for intra coding in H.264 under energy constraints

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High Technology Letters 2010年第3期16卷 274-279页

作者： Gao Xuejun Lam kin man ZhuoLi ShenLansun Signal and Information Processing Laboratory Beijing University of Technology Beijing 100124 P.R. China Centre for Signal Processing Department of Electronic and Information Engineering the Hong Kong Polytechnic University Kowloon Hong Kong P.R. China

In this paper, the complexity of intra coding is first analyzed so as to achieve a weight of complexity measurement for each intra mode. Then, a new complexity scalable control algorithm for intra coding in H. 264 is proposed, based on the rearrangement of the order of candidate modes and an efficient complexity allocation and control （CAAC） scheme at the macroblock （MB） level. The candidate modes of each MB are rearranged according to the local-edge information. Experimental results show that our proposed algorithm can make an appropriate cut-off point of the candidate modes sequence adaptively according to the current energy condition of a mobile device, so as to adjust the complexity at any level while maximizing the video quality, which can prolong the operational lifetime of the battery with minimum degradation in video quality.

关键词： complexity scalable control complexity allocation rearrangement of candidate modes intra coding H. 264 energy constraints

Small Molecule Organic Nanostructures—Fabrication and Properties

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Journal of Materials Science & Technology 2008年第4期24卷 563-568页

作者： A.B.Djurii A.M.C.Ng Kai-Yin CHEUNG man-kin FUNG Wai-kin CHAN Department of Physics University of Hong KongPokfulam RoadHong KongHong Kong SARChina Department of Chemistry University of Hong KongPokfulam RoadHong KongHong Kong SARChina

Organic materials are of great interest for the development of low cost electronic and optoelectronic devices. Although majority of research on organic materials is concerned with synthesis of novel compounds and organic thin films, organic nanostructures are attracting increasing interest in recent years. We briefly review different growth methods of organic nanostructures, which can be roughly divided into vapor deposition methods and self-assembly techniques in solution. Then we highlight some interesting properties of organic nanostructures, as well as possible applications, includinf field emission, electronic and optoelectronic devices.

关键词： Organic nanostructures Self-assembly Vapor deposition

Design, Synthesis, Photophysical Studies and Electrochemistry of Carbazole-, Oxadiazole-, and Oxadiazole-Triarylamine-Containing Rhenium(Ⅰ) Diimine Alkynyl Complexes

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Chinese Journal of Chemistry 2014年第10期32卷 1015-1021页

作者： Wai-kin Chung Keith man-Chung Wong Vivian Wing-Wah Yam and Department of ChemistryThe University of Hong KongPokfulam RoadHong KongChina

A series of rhenium(I)diimine alkynyl complexes with various electron-and hole-transporting moieties has been synthesized and *** electronic absorption,emission and electrochemical properties have also been studied.

关键词： electrochemistry luminescence metal alkynyl rhenium(Ⅰ)diimine,UV/Vis spectroscopy

‘One Health' for the people of Hong Kong and the world

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Science China(Life Sciences) 2016年第10期59卷 1068-1070页

作者： kin-Hang Kok Hei-man Vincent Tang Dong-Yan Jin Department of Biochemistry University of Hong Kong

Translational medicine refers to the conversion of scientific discoveries into improvements in medical practice. ＇From bench to bedside and back＇ is a phrase that is often used to describe the two-way information flow in translational medicine. On one hand, scientists working at the bench make new discoveries that enable clinicians to revolutionize patient care, while on the other hand, clinical investigations at the bedside provide new knowledge about diseases, which stimulate basic research at the bench.

关键词：世界香港健康科学发现临床医生临床调查基础研究信息流

Structures of Textile-apparel Supply Chain: Concepts and Cases

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Journal of Donghua University(English Edition) 2005年第2期22卷 130-134页

作者：曹宁张志明 kin man To Chester Keng Po Ng Roger Institute of Textiles and Clothing The Hong Kong Polytechnic University Hong Kong

In recent years, supply chain management （SCM） has been in popularity as a new management philosophy for all industries, including textile and apparel industries. The textile-apparel supply chain is relatively complex because it encompasses many participants such as yarn manufacturers, fabric manufacturers, garment manufacturers and retailers. Although many scholars are engaged in researching SCM in textile and apparel industries, a systematic classification of textile-apparel chain does not exist. The paper proposes three types of textile-apparel chain, nominated vertical integration chain, traditional sourcing chain and 3P-hub （third party as the hub） chain. Different coordinators exist in different types of chain. Three Hong Kong headquartered companies, Esquel Group, TAL Apparel Ltd., and Li ＆ Fang （Trading） Ltd. are used as cases responding to each type of the structures respectively.

关键词： supply chain textile-apparel chain coordinator structure