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Sex-based differences in histology,staging,and prognosis among 2983 gastric cancer surgery patients

World Journal of Gastroenterology 2022年第9期28卷 933-947页

作者： Yonghoon Choi Nayoung kim ki wook kim Hyeong Ho Jo Jaehyung Park Hyuk Yoon Cheol Min Shin Young Soo Park Dong Ho Lee Hyeon Jeong Oh Hye Seung Lee Young Suk Park Sang-Hoon Ahn Yun-Suhk Suh Do Joong Park Hyung-Ho kim Ji-Won kim Jin Won kim Keun-wook Lee Won Chang Ji HoonPark Yoon Jin Lee Kyoung Ho Lee Young Hoon kim Department ofInternal Medicine Seoul National University Bundang HospitalSeongnam 13620South Korea Nayoung Department of Internal Medicine Seoul National University College of MedicineSeoul 03080South Korea Department of Pathology Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Pathology Seoul National University College of MedicineSeoul 03080South Korea Department of Surgery Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Surgery Seoul National University College of MedicineSeoul 03080South Korea Department of Radiology Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Radiology Seoul National University College of MedicineSeoul 03080South Korea

BACKGROUND Few studies have been conducted on sex differences in the incidence, pathophysiology, and prognosis of gastric cancer(GC).AIM To analyze the differences in GC characteristics according to sex in patients who underwent surgical treatment for *** A total of 2983 patients diagnosed with gastric adenocarcinoma who received surgical treatment at the Seoul National University Bundang Hospital between 2003 and 2017 were *** clinicopathological characteristics, histologic type of GC, overall and GC-specific survival rates, and associated risk factors were *** Among the 2983 patients, 2005(67.2%) and 978(32.8%) were males and females, *** average age of the female group(59.36 years) was significantly younger than that of the male group(61.66 years;P < 0.001).Cancer of the gastric body(P < 0.001) and diffuse-type histology(P < 0.001) were more common in females than in *** trend was more prominent in females younger than 60 years of age, with a significantly higher proportion of diffuse-type cancer than in the male *** of sex, diffuse-type GC was more common in younger patients, and the proportion of intestinal-type GC increased with *** overall survival rate was significantly higher in females(P < 0.001).However, this difference disappeared for GC-specific survival(P = 0.168), except for the poor GC-specific survival rate in advanced-stage cancer(stage Ⅲ or above) in females(P = 0.045).The risk factors for GC-related mortality were older age, upper location of GC, and diffuse-or mixed-type *** terms of comorbidities, more males died from diseases other than GC, including other malignancies such as lung cancer, hepatocellular carcinoma, and pancreatic cancer, and respiratory diseases such as interstitial lung disease and chronic obstructive pulmonary disease, while there were relatively more cardiovascular or cerebrovascular deaths in *** Sex-based differences in GC were

关键词： Gastric cancer Histology Prognosis Sex difference Survival

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Liquid crystal-powered Mie resonators for electrically tunable photorealistic color gradients and dark blacks

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Light(Science & Applications) 2022年第6期11卷 1098-1108页

作者： Trevon Badloe Joohoon kim Inki kim Won-Sik kim wook Sung kim Young-ki kim Junsuk Rho Department of Mechanical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Department of Biophysics Institute of Quantum BiophysicsSungkyunkwan UniversitySuwon 16419Republic of Korea Department of Intelligent Precision Healthcare Convergence Sungkyunkwan UniversitySuwon 16419Republic of Korea Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Department of Electrical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea POSCO-POSTECH-RIST Convergence Research Center for Flat Optics and Metaphotonics Pohang 37673Republic of Korea National Institute of Nanomaterials Technology(NINT) Pohang 37673Republic of Korea

Taking inspiration from beautiful colors in nature,structural colors produced from nanostructured metasurfaces have shown great promise as a platform for bright,highly saturated,and high-resolution *** plasmonic and dielectric materials have been employed to produce static colors that fulfil the required criteria for high-performance color printing,however,for practical applications in dynamic situations,a form of tunability is *** of the additive color palette of red,green,and blue enable the expression of further colors beyond the three primary colors,while the simultaneous intensity modulation allows access to the full color ***,we demonstrate an electrically tunable metasurface that can represent saturated red,green,and blue pixels that can be dynamically and continuously controlled between on and off states using liquid *** use this to experimentally realize ultrahigh-resolution color printing,active multicolor cryptographic applications,and tunable pixels toward high-performance full-color reflective displays.

关键词： saturated printing colors

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Single-crystalline-level properties of ultrathin SrRuO_(3) flexible membranes with wide and clean surface

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npj Flexible Electronics 2022年第1期6卷 210-215页

作者： Dongha kim wook ki Jung Shinbuhm Lee Department of Physics and Chemistry Department of Emerging Materials ScienceDGISTDaegu 42988Republic of Korea Agency for Defence Development Daejeon 34186Republic of Korea

Transferring single-crystalline(SC)membranes to flexible substrates has been increasingly studied,enabling emerging functionality and enhanced performance of various devices.A commonly used support-assisted transfer process inevitably leaves dirty residue on material surfaces,limiting the further development of surface-related ***,we scale down the thickness of flexible SC SrRuO_(3)(SRO)membranes to 15 nm with a clean surface area of 2.5×2.5 mm^(2).This is accomplished by making the polyethylene terephthalate(PET)substrate surface hydrophilic via oxygen plasma treatment,thereby reducing the surface *** ultrathin,clean,wide,and flexible SC SRO membranes guarantee a high transmittance of up to 60%,a low resistivity of 10^(−4)−10^(−3)Ωcm at room temperature,and band ferromagnetism below 150 K with a high magnetic moment of~0.5μB/Ru at 10 *** SC-level properties of our SRO membranes imply their potential use in state-of-the-art platforms for next-generation electronics and energy devices.

关键词： crystalline thereby guarantee

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Microstructures and Mechanical Properties of Rapidly Solidified Mg-Al-Zn-MM Alloys

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Journal of Materials Science & Technology 2008年第1期24卷 89-92页

作者： Yeon-wook kim Department of Advanced Materials Engineering Keimyung University Daegu 704-701Korea

Mg-Al-Zn-M M （misch metal） alloy powders were manufactured by inert gas atomization and the characteristics of alloy powders were *** spite of the low fluidity and easy oxidation of the magnesium melt,the spherical powder was made successfully with the improved three piece nozzle systems of gas atomization unit. It was found that most of the solidified powders with particles size of less than 50μm in diameter were single crystal and the solidification structure of rapidly solidified powders showed a typical dendritic morphology because of supercooling prior to *** spacing of secondary denrite arms was deceasing as the size of powders was *** rapidly solidified powders were consolidated by vacuum hot extrusion and the effects of misch metal addition to AZ91 on mechanical properties of extruded bars were also *** extrusion of the rapidly solidified powders,their dendritic structure was broken into fragments and remained as grains of about 3μm in *** Mg-Al-Ce intermetallic compounds formed in the interdendritic regions of powders were finely broken,*** tensile strength and ductility obtained in as-extruded Mg-9 wt pct Al-1 wt pct Zn-3 wt pct MM alloy wereσ-（T.S.） =383 MPa andε=10.6%,*** of these improvements on mechanical properties were resulted from the refined microstructure and second-phase dispersions.

关键词： Mg alloy Gas atomization Misch metal Hot extrusion

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Recent advances in stem cell therapy for neurodegenerative disease: Three dimensional tracing and its emerging use

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World Journal of Stem Cells 2021年第9期13卷 1215-1230页

作者： Il-Kwon kim Jun-Hee Park Bomi kim ki-Chul Hwang Byeong-wook Song Institute for Bio-Medical Convergence Catholic Kwandong University International St.Mary’s HospitalIncheon Metropolitan City 22711South Korea Institute for Bio-Medical Convergence College of MedicineCatholic Kwandong UniversityGangwon-do 25601South Korea

Neurodegenerative disease is a brain disorder caused by the loss of structure andfunction of neurons that lowers the quality of human life. Apart from the limitedpotential for endogenous regeneration, stem cell-based therapies hold considerablepromise for maintaining homeostatic tissue regeneration and enhancingplasticity. Despite many studies, there remains insufficient evidence for stem celltracing and its correlation with endogenous neural cells in brain tissue with threedimensionalstructures. Recent advancements in tissue optical clearing techniqueshave been developed to overcome the existing shortcomings of cross-sectionaltissue analysis in thick and complex tissues. This review focuses on recentprogress of stem cell treatments to improve neurodegenerative disease, andintroduces tissue optical clearing techniques that can implement a threedimensionalimage as a proof of concept. This review provides a more comprehensiveunderstanding of stem cell tracing that will play an important role inevaluating therapeutic efficacy and cellular interrelationship for regeneration inneurodegenerative diseases.

关键词： Cell tracing Neurodegenerative disease Stem cells Three-dimensional imaging Tissue clearing

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QKD system with fast active optical path length compensation

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Science China(Physics,Mechanics & Astronomy) 2017年第6期60卷 1-7页

作者： Byung Kwon Park Min Soo Lee Min ki Woo Yong-Su kim Sang-wook Han Sung Moon Center for Quantum Information Korea Institute of Science and Technology Department of Nano-materials Science and Engineering Korea University of Science and Technology

We develop a quantum key distribution (QKD) system with fast active optical path length compensation. A rapid and reliable active optical path length compensation scheme is proposed and applied to a plug-and-play QKD system. The system monitors changes in key rates and controls it is own operation automatically. The system achieves its optimal performance within three seconds of operation, which includes a sifted key rate of 5.5 kbps and a quantum bit error rate of less than 2% after an abrupt temperature variation along the 25 km quantum channel. The system also operates well over a 24 h period while completing more than 60 active optical path length compensations.

关键词： quantum key distribution optical path length compensation plug and play field programmable gate array

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Ionizing terahertz waves with 260 MV/cm from scalable optical rectification

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Light(Science & Applications) 2024年第6期13卷 1075-1087页

作者： Hyeongmun kim Chul Kang Dogeun Jang Yulan Roh Sang Hwa Lee Joong wook Lee Jae Hee Sung Seong Ku Lee ki-Yong kim Advanced Photonics Research Institute GISTGwangju61005Korea Department of Physics and Optoelectronics Convergence Research Center Chonnam National UniversityGwangju61186Korea Pohang Accelerator Laboratory POSTECHPohang37673Korea Center for Relativistic Laser Science Institute for Basic ScienceGwangju61005Korea Institute for Research in Electronics and Applied Physics Department of PhysicsUniversity of MarylandCollege ParkMaryland20742USA

Terahertz(THz)waves,known as non-ionizing radiation owing to their low photon energies,can actually ionize atoms and molecules when a sufficiently large number of THz photons are concentrated in time and ***,we demonstrate the generation of ionizing,multicycle,15-THz waves emitted from large-area lithium niobate crystals via phase-matched optical rectification of 150-terawatt laser pulses.A complete characterization of the generated THz waves in energy,pulse duration,and focal spot size shows that the field strength can reach up to 260 megavolts per *** particular,a single-shot THz interferometer is employed to measure the THz pulse duration and spectrum with complementary numerical *** intense THz pulses are irradiated onto various solid targets to demonstrate THz-induced tunneling ionization and plasma *** study also discusses the potential of nonperturbative THz-driven ionization in gases,which will open up new opportunities,including nonlinear and relativistic THz physics in plasma.

关键词： optical interferometer matched

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Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique

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Asian Journal of Andrology 2018年第1期20卷 80-84页

作者： Dae Yul Yang Kyungtae Ko Seong Ho Lee Du Geon Moon Jong wook kim Won ki Lee Department of Urology College of Medicine Hallym University Chuncheon Korea Department of Urology College of Medicine Korea University Seoul Korea.

There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a newly developed filler for soft-tissue augmentation. We evaluated the efficacy and safety of using a novel technique to inject cross-linked dextran gel for glans penis augmentation during a 24-week follow-up study. This prospective, single-arm, multicenter study enrolled twenty healthy adult men who underwent glans penis augmentation between June and August 2013. Cross-linked dextran gel was injected into the glans penis using a simple and easy technique. The sizes of the glans penis and individual satisfaction were assessed. Any adverse event was also reported. A total of 18 individuals were analyzed; two of them were lost to follow-up. The mean procedure time and injected volume were about 30 rain and 6.6 ＋- 0.9 ml, respectively. The mean surface areas of the glans at baseline and 24 weeks were 20.0 _＋ 3.5 cm2 and 33.6 -＋ 5.4 cm2, respectively, representing a mean increase of 68.7% _＋ 14.0% （P 〈 0.001）. Sixteen individuals （88.9%） were satisfied with the outcomes, and none were dissatisfied. There were no serious adverse events during the study. Cross-linked dextran gel injection for glans penis augmentation was easy and showed a significant augmentative effect on the glans penis, good durability, and was well tolerated without serious adverse events. Therefore, cross-linked dextran gel injection may be an effective, new technique for glans penis augmentation.

关键词： cosmetic technique dermal fillers dextran glans penis

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Incorporation of Ionic Conductive Polymers into Sulfide Electrolyte-Based Solid-State Batteries to Enhance Electrochemical Stability and Cycle Life

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Energy & Environmental Materials 2024年第6期7卷 4-12页

作者： Juhyoung kim Woonghee Choi Seong-Ju Hwang Dong wook kim Advanced Materials Division Korea Research Institute of Chemical Technology(KRICT)Daejeon 34114Korea Department of Material Science and Engineering Yonsei UniversitySeoul 03722Korea Department of Material Science and Engineering Seoul National UniversitySeoul 08826Korea Advanced Materials and Chemical Engineering University of Science and Technology(UST)Daejeon 34113Korea

Sulfide-based inorganic solid electrolytes are promising materials for high-performance safe solid-state *** high ion conductivity,mechanical characteristics,and good processability of sulfide-based inorganic solid electrolytes are desirable properties for realizing high-performance safe solid-state batteries by replacing conventional liquid ***,the low chemical and electrochemical stability of sulfide-based inorganic solid electrolytes hinder the commercialization of sulfide-based safe solid-state ***,the instability of sulfide-based inorganic solid electrolytes is intensified in the cathode,comprising various *** this study,carbonate-based ionic conductive polymers are introduced to the cathode to protect cathode materials and suppress the reactivity of sulfide *** instruments,including electrochemical spectroscopy,X-ray photoelectron spectroscopy,and scanning electron microscopy,confirm the chemical and electrochemical stability of the polymer electrolytes in contact with sulfide-based inorganic solid ***-based solid-state cells show stable electrochemical performance over 100 cycles when the ionic conductive polymers were applied to the cathode.

关键词： composite cathode electrochemical stability ionic conductive polymer solid-state battery sulfide solid electrolyte

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Strangulated small bowel hernia through the port site:A case report

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World Journal of Gastroenterology 2008年第44期14卷 6881-6883页

作者： Jun Hyun Lee wook kim Department of Surgery Holy Family HospitalCollege of MedicineThe Catholic University of KoreaBucheon 420-717South Korea

Port site hernia develops through a fascial or peritoneal layer that was inadequate or not repaired. It is a rare complication of laparoscopic surgery which may lead to serious problems. Here,we present a 77-year-old female,diagnosed with a small bowel hernia through a 10-mm port site. We had performed ten cases of laparoscopy-assisted distal gastrectomy before this case. The patient complained of left lower abdominal pain with a palpable mass. Abdominal CT showed an incarcerated small bowel hernia and the patient underwent segmental resection of the strangulated small bowel through a minimally extended port site incision.

关键词： Port site hernia Strangulated small bowel Minimally extended port site incision

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