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Posterior Lumbar Interbody Fusion versus Posterolateral Fusion in Surgical Treatment of Lumbar Spondylolithesis

Open Journal of Modern Neurosurgery 2020年第1期10卷 135-145页

作者： khaled ismail abdelaziz Radwan Nouby Mohammad Fekry Elshirbiny Ahmed Salaheldin Mahmoud Department of Neurosurgery Faculty of Medicine Aswan University Aswan Egypt Department of Neurosurgery Faculty of Medicine Assiut University Assiut Egypt

Background: The optimal surgical technique for lumbar spondylolithesis remains debated. Although posterior lumbar interbody fusion (PLIF) theoretically offers more advantages than posterolateral lumbar fusion (PLF), the evidence remains inconclusive. Aim: The aim of this study is to compare the clinical and functional outcomes of PLIF versus PLF in patients with lumbar spondylolithesis. Patients and Methods: We enrolled 38 patients with lumbar spondylolithesis (degenerative and isthmic) who underwent PLIF (N = 19) or PLF (N = 19). We collected operative data and performed follow-up for 12 months after the surgery. The collected data were analyzed using the SPSS software to detected significant differences between both groups. Results: The PLF and PLIF groups exhibited similar pre-operative characteristics between both groups in terms of age (p = 0.57), sex (p = 0.73), clinical presentation (p = 1), required levels of fixation (p = 1), pre-operative VAS score (p = 0.43) or muscle weakness (p = 1). However, the PLIF group had significantly more blood loss and longer operative time than the PLF group. Moreover, both groups had similar levels of postoperative pain (up to six months after surgery), and post-operative complications. The rates of arthrodesis were higher in PLIF group than PLF group within six months while no significant difference within 12 months of follow-up. Conclusion: In our comparative study, we achieved comparison between pedicle screw fixation with posterolateral fusion alone (PLF) in compare with pedicle screw fixation with posterior lumbar interbody fusion (PLIF). Results indicate better results of fusion rate in PLIF as regards arthrodesis with slightly more rate of complication than PLF. So we recommend PLIF in cases of lumbar spondylolithesis than PLF.

关键词： Arthrodesis Lumbar Spondylolithesis Posterior Lumbar Interbody Fusion (PLIF) Posterolateral Fusion (PLF)

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Static Analysis of Functionally Graded Sandwich Plates Using an Efficient and Simple Refined Theory

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Chinese Journal of Aeronautics 2011年第4期24卷 432-433页

作者： Hadj Henni abdelaziz Hassen Ait ATMANE ismail MECHAB Lakhdar BOUMIA Abdelouahed TOUNSI Adda Bedia El ABBAS Laboratoire des Matériaux et Hydrologie Université de Sidi Bel Abbes Département de Génie Civil Université Ibn Khaldoun Département de Génie Civil Faculté de Génie Civil et d'Architecture Univesité de Chlef Département de Physique Université de Sidi Bel Abbes

In this paper, a new displacement based high-order shear deformation theory is introduced for the static response of functionally graded sandwich plate. Unlike any other theory, the number of unknown functions involved is only four, as against five in case of other shear deformation theories. The theory presented is variationally consistent, has strong similarity with classical plate theory in many aspects, does not require shear correction factor, and gives rise to transverse shear stress variation such that the transverse shear stresses vary parabolically across the thickness satisfying shear stress free surface conditions. Two common types of functionally graded sandwich plates, namely, the sandwich with fimctionally graded facesheet and homogeneous core and the sandwich with homogeneous facesheet and functionally graded core, are considered. Governing equations are derived from the principle of virtual displacements. The closed-form solution of a simply supported rectangular plate subjected to sinu- soidal loading has been obtained by using the Navier method. The validity of the present theory is investigated by comparing some of the present results with those of the classical, the first-order and the other higher-order theories. It can be concluded that the proposed theory is accurate and simple in solving the static bending behavior of functionally graded sandwich plates.

关键词： functionally graded materials sandwich plates refined plate theory bending Navier solution

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Experimental and computational chemical studies on the cationic furanylnicotinamidines as novel corrosion inhibitors in aqueous solutions

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Chinese Journal of Chemical Engineering 2020年第2期28卷 477-491页

作者： abdelaziz S.Fouda Mohamed A.ismail Rabab M.Abou-shahba Walaa A.Husien Esraa S.EL-Habab Ashraf S.Abousalem Department of Chemistry Faculty of ScienceEl-Mansoura UniversityEl-Mansoura 35516Egypt Department of Chemistry Faculty of ScienceAl-Azhar UniversityEgypt Quality Control Laboratory Operation DepartmentJOTUNEgypt

The corrosion inhibition action of three newly synthesized furanylnicotinamidine derivatives namely: 6-[5-{4(dimethylamino)phenyl}furan-2-yl]nicotinamidine(MA-1256), 6-[5-(4-chlorophenyl)furan-2-yl]nicotinamidine(MA-1266), and 6-[5-{4-(dimethylamino)phenyl}furan-2-yl]nicotinonitrile(MA-1250) on carbon steel(C-steel) was investigated in 1.0 mol·L-1 HCl solution by weight loss(WL), potentiodynamic polarization(PP), electrochemical impedance spectroscopy(EIS), and electrochemical frequency modulation(EFM)techniques. Morphological analysis was performed on the uninhibited and inhibited C-steel using atomic force microscope(AFM) and Infrared Spectroscopy(ATR-IR) methods. The effect of temperature was studied and discussed. Inspection of experimental results revealed that the inhibition efficiency(IE) increases with the incremental addition of inhibitors and with elevating the temperature of the acid media. The adsorption of furanylnicotinamidine derivatives on C-steel follows Temkin’s isotherm. PP studies indicated that the investigated compounds act as mixed-type inhibitors and showed that p-dimethylaminophenyl furanylnicotinamidine derivative(MA-1256) was the most efficient inhibitor among the other studied derivatives with IE reached(95%)at 21 × 10-6 mol·L-1. MA-1266 is highly soluble in aqueous solution and has non-toxicity profile with LC50 N 37 mg·L-1. Thus, MA-1266 can be a promising green corrosion inhibitor candidate with IE N 91% at 21× 10-6 mol·L-1. The experiments were coupled with computational chemical theories such as quantum chemical and molecular dynamic methods. The experimental results were in good agreement with the computational outputs.

关键词： Acid corrosion C-steel Furanylnicotinamidines Green inhibitor Computational chemical methods

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Phytochemical and biological activities of Crataegus sinaica growing in Egypt

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Asian Pacific Journal of Tropical Medicine 2010年第4期3卷 257-261页

作者： Alaa Tawfeek Refaat Abdelaaty abdelaziz Shahat Nermine Ahmed Ehsan Nemat Yassin Faiza Hammouda Elsayed Abou Tabl Shams Imbabi ismail Phytochemistry Department National Research CenterEgypt National Liver Institute Monofia UniversityEgypt Pharmacology Department National Research CenterEgypt Pharmacognosy Department Faculty of PharmacyCairo UniversityEgypt

Objective:To evaluate the cardiac activity and hepatoprotection of Crataegus sinaica (***).Methods:All the isolated compounds were isolated by open-column liquid chromatography(CC) using sephadex LH-20 as stationary *** of the column was performed with EtOH or *** phytochemical investigation of the young stem of *** for the first time together with the leaves and flowers lead to the isolation and identification of quercetin,hyperoside,vitexin-2"-0-rhamnoside,epicatechin,procyanidin B2 and procyanidins ***:Rats treated with the low and high dose of *** leaves with flowers extract showed 15%and 17%reduction in the heart rate,and reduction in the STsegment by 107%and 57%;*** T-amplitude was decreased by 59%of the high dose *** the other hand,the young steins and leaves with flowers extracts of *** on primary culture of rat hepatocytes monolayer indicated a hepatoprotection for the total extract,ethyl acetate,butanol,and chlor of orm fractions at 100μg/mL,75μg/mL,50μg/mL,and 25μg/mL; ***:The results of these chemical and biological studies suggest the use of *** growing in Egypt as a preventive drug against cardiovascular and hepatic diseases. The chemical studies suggest the use of woody young stems as a newly investigated bioactive *** extraction of unsaturated fatty acids from the seeds of the plant would serve as a good health and nutritive product.

关键词： Crataegus sinaica Cardiovascular Hepatoprotection Flavonoids Proanthocyanidins High performance liquid chromatography

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Metformin alleviates LTA-induced inflammatory response through PPARγ/MAPK/NF-κB signaling pathway in bovine mammary epithelial cells

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BIOCELL 2022年第11期46卷 2443-2454页

作者： abdelaziz ADAM IDRISS ARBAB CHUNQING YIN XUBIN LU YAN LIANG ismail MOHAMED ABDALLA AMER ADAM IDRIS TIANLE XU YONGJIANG MAO ZHANGPING YANG College of Animal Science and Technology Yangzhou UniversityYangzhou225009China Joint International Research Laboratory of Agriculture and Agri-Product Safety ofMinistry of Education of China Yangzhou UniversityYangzhou225009China Biomedical Research Institute Darfur CollegeNyala63313Sudan Shandong Haiding husbandry Co. Ltd.Jinan250100China

Mastitis is a common inflammatory cow mammary infection;that causes significant economic loss in dairy *** the interesting connection between metformin’s anti-inflammatory function and mastitis model induced by LTA in pbMECs,our objective was to prove that metformin was beneficial in suppressing proinflammatory response induced by LTA through modulation of mitogen-activated protein kinase(MAPK)and nuclear factor kappa B(NF-κB)signaling pathways and activation of peroxisome proliferator-activated receptor-γ(PPARγ)in *** proliferation of cells and mRNA expression were measured using EdU assay and quantitative reverse transcriptase-polymerase chain reaction(qRT-PCR).Immunoblotting and immunofluorescence analysis were conducted to evaluate the expression of target proteins in inflammatory and anti-inflammatory responses to metformin and ***,pbMECs were allowed to treat with the PPAR antagonist GW9662,and inflammatory markers were detected in the *** results showed that LTA concentration at 100μg/mL significantly stimulated the MAPK14,IL-6 and IL-1βmRNA expressions compared to the control cells(P<0.05)in dose-dependent tests for *** suppressed the phosphorylation expressions of MAPK(ERK1/2,p38,and JNK)in LTA-stimulated *** also reduced the protein expression of NF-κB,interleukin-8(IL-8),interleukin-1β(IL-1β)and interleukin-6(IL-6)in pbMECs pretreated with *** administration activated PPARγphosphorylation by up-regulating the expression of PPARγin LTA-stimulated *** with GW9662 resulted in increased IL-6 expression,which was reversed by *** findings collectively indicated that metformin act to attenuate LTA-stimulated inflammatory response in pbMECs by suppressing MAPK and NF-κB activation via a mechanism partially dependent on PPARγ*** results suggested that metformin could function as an anti-inflammatory drug in the treatment of mastitis.

关键词： Metformin LTA Primary bovine mammary epithelial cell Anti-inflammatory effect PPARγ Nuclear factor-κB Mitogen-activated protein kinase

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A New Approach to University IT Project Portfolio Management Based on Multi-Criteria Methods and the COBIT 5 Governance Framework

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Journal of Systems Science and Information 2023年第5期11卷 636-654页

作者： Majida LAAZIRI Khaoula BENMOUSSA abdelaziz EL ALAOUI EL AMRANI Ahmed MOUCHTACHI Structural Engineering Intelligent Systems and Electrical Energy LaboratoryNational Graduate School of Arts and CraftsHassan Ⅱ UniversityCasablanca 20670Morocco Higher Normal School Moulay Ismail UniversityMeknes 50050Morocco

Project portfolio management is a major challenge for some *** most organizations,there are a large number of projects active at the same time,some not necessarily delivering value or not aligned with their strategic *** universities face a lot of uncertainties when selecting and prioritizing the projects that make up their *** addition,the achievement of those who are aligned with the strategy of the university becomes a great *** to ensure good project portfolio management,the implementation of selection and prioritization methods and processes becomes *** the project portfolio management to be effective,it is necessary to establish a structured method adapted to the needs and strategy of the *** this context,this paper proposes a method for selecting and prioritizing projects within the framework of the portfolio management dedicated to universities,which can promote harmony between the university’s strategy,the needs and the priority objectives for enable better *** method is based on the processes of the COBIT 5 good practice framework,and on the multi-criteria decision-making methods AHP,TOPSIS and the WSM technique,thus,it proposes seven project selection criteria based on the five axes IT governance strategies and two catalysts derived from COBIT 5 *** evaluation and validation of this method was applied in the portfolio management of the Abdelmalek Essaadi Moroccan University(AUE).The result shows that this proposed method has made it possible to make a better selection and prioritization of the portfolio of projects of Abdelmleek Essaadi University having the most value.

关键词： IS governance information systems project portfolio management university governance project prioritization information technology(IT) good practice framework COBIT 5 APO05 multi-criteria decision-making method AHP TOPSIS WSM

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Integrative herbal treatments of diabetes in Beni Mellal region of Morocco

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Journal of Integrative Medicine 2019年第2期17卷 93-99页

作者： Hanae Naceiri Mrabti Nidal Jaradat Mohamed Reda Kachmar abdelaziz Ed-Dra Abdelilah Ouahbi Yahia Cherrah Moulay El Abbes Faouzi Faculty of Medicine and Pharmacy Pharmacokinetic Team Laboratory of Pharmacology and Toxicology Université Mohammed V-Souissi Department of Pharmacy Faculty of Medicine and Health Sciences An-Najah National University Faculty of Sciences Health and Environment Laboratory Plant Protection Team Moulay Ismail University Faculty of Science Team of Microbiology and Health Laboratory of Chemistry-Biology Applied to the Environment Moulay Ismail University

Objectives: Diabetes is one of the most life-threatening chronic metabolic disorders and is considered a global health problem due to its prevalence and incidence. In Morocco, several herbal preparations are utilized to treat this disease. For this reason, the current study aimed to identify and to collect data about the medicinal plants utilized in folk medicine for the treatment of diabetes in the Beni Mellal region of ***: An ethnobotanical survey was carried out among 400 herbalists, competent villagers and traditional healers from the Beni Mellal region through direct interviews using a semistructured ***: Forty-five medicinal plants belonging to 25 families were identified for their use in diabetes treatment. Interview results showed that the most frequently used plants were Olea europaea, Salvia officinalis, Allium sativum and Trigonella foenum-graecum, with a relative frequency of citation values of24.3%, 23.0%, 22.5% and 20.5%, respectively. Moreover, in this study, the Fabaceae family was the most commonly reported plant family, and the leaves and roots were the most commonly used parts, for the treatment of ***: The Beni Mellal region of Morocco has an important floristic biodiversity of plants used to treat diabetes in traditional medicinal practice. This result provides a good database for pharmacological screenings in the search for plant-based antidiabetic medications.

关键词： Integrative medicine Medicinal plants Diabetes Beni Mellal Morocco Questionnaire

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Qualification of Three Analytical Wake Models

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Journal of Mechanics Engineering and Automation 2016年第4期6卷 205-211页

作者： Naima Charhouni Mohammed Sallaou abdelaziz Arbaoui Mechanics and Integrated Engineering (M2I) department Moulay Ismail University ENSAM Meknes BP 4024 Morocco

The decrease of wind velocity （wake losses） in downstream area of wind turbine is generally quantified using wake models. The overall estimated power of wind farm varies according to reliability of wake model used, however it＇s unclear which model is most appropriate and able to give a high performance in predicting wind velocity deficit. In this subject, a qualification of three analytical wake models （Jensen, lshihara and Frandsen） based on three principal criteria is presented in this paper：（i） the parsimony which characterizes the inverse of model complexity, （ii） the accuracy of estimation in which wake model is compared with the experimental data and （iii） imprecision that is related to assumptions and uncertainty on the value of variables considered in each model. This qualitative analysis shows the inability of wake models to predict wind velocity deficit due to the big uncertainty of variables considered and it sensitivity to wind farm characteristic.

关键词： Wind farm wind turbine wake models parsimony accuracy imprecision.

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A Sensor Web for Real-Time Groundwater Data Monitoring in Morocco

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Journal of Geographic Information System 2014年第6期6卷 613-623页

作者： Aniss Moumen Hassane Jarar Oulidi Meryem Agadi Mohamed Nehmadou Mohamed Ben-Daoud Amel Barich abdelaziz Mridekh Bouabid El Mansouri Said Boutaleb Karim Ben Hachmi Mohammed Ali Essahlaoui Samir Eljaafari Geosciences Laboratory of Natural Resources (GeoNaRes) Faculty of Sciences IbnTofial University Kenitra Morocco Department of Mathematics Informatics and Geomatics Hassania School of Public Works (EHTP) Casablanca Morocco Laboratory of Chemical Engineering and Environment Faculty of Science and Technology Hassan II University Mohammedia Morocco Applied Geology and Geo-Environment Laboratory Faculty of Sciences Ibn Zuhr University Agadir Morocco Department of Biology Faculty of Science Moulay Ismail University Meknes Morocco Instituto Andaluz de Ciencias de la Tierra UGR-CSIC Granada Spain Water Sciences and Environmental Engineering Group Department of Geology Faculty of Science Moulay Ismail University Meknes Morocco

This article presents research and development of an interoperable platform to facilitate, monitor and coordinate groundwater data sharing. This system was orchestrated by a number of services described by Open Geospatial Consortium (OGC) such as Sensor Observation Service (SOS) and other services for the use of mapping data, Web Feature Services (WFS), Web Map Service (WMS), and catalogue services (CSW). An important activity for our project was the establishment of a portal for geographic data and services. Geoportal developed for this project will promote and facilitate access to groundwater data and share theme more openly. Otherwise our system has been designed to provide a powerful tool that enhances the ability of regional staff to monitor near real-time groundwater data (i.e.?piezometric level) and as a result will help provide a more effective response to environmental upsets.

关键词： Sensor Web OGC Geoportal Geocatalog Monitoring Groundwater Morocco

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Experimental and computational chemical studies on the cationic furanylnicotinamidines as novel corrosion inhibitors in aqueous solutions

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中国化学工程学报（英文版） 2020年第2期

作者： abdelaziz S.Fouda Mohamed A.ismail Rabab M.Abou-shahba Walaa A.Husien Esraa S.EL-Habab Ashraf S.Abousalem

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