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The evolution of copulation frequency and the mechanisms of reproduction in male Anolis lizards

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Current Zoology 2014年第6期60卷 768-777页

作者： Michele A. jOHNSON Mafia Veronica LOPEZ Tara K. WHITTLE Bonnie K. KIRCHER Alisa K. DILL Divina varghese juli WADE Trinity University Department of Biology One Trinity Place San Antonio Texas 78212 USA Michigan State University Departments of Psychology and Zoology East Lansing Michigan 48824 USA

The evolution of many morphological structures is associated with the behavioral context of their use, particularly for structures involved in copulation. Yet, few studies have considered evolutionary relationships among the integrated suite of structures associated with male reproduction. In this study, we examined nine species of lizards in the genus Anolis to determine whether larger copulatory morphologies and higher potential for copulatory muscle performance evolved in association with higher copulation rates. In 10--12 adult males of each species, we measured the size of the hemipenes and related muscles, the seminiferous tubules in the testes, and the renal sex segments in the kidneys, and we assessed the fiber type composition of the muscles associated with copulation. In a series of pbylogenetically-informed analyses, we used field behavioral data to determine whether observed rates of copulation were associated with these *** found that species with larger hemipenes had larger fibers in the RPM （the retractor penis magnus, a muscle that controls hemipenis movement）, and that the evolution of larg- er hemipenes and RPM fibers is associated with the evolution of higher rates of copulatory behavior. However, the sizes of the seminiferous tubules and renal sex segments, and the muscle fiber composition of the RPM, were not associated with copulation rates. Further, body size was not associated with the size of any of the reproductive structures investigated. The results of this study suggest that peripheral morphologies involved in the transfer of ejaculate may be more evolutionarily labile than internal structures involved in ejaculate production.

关键词： Anolis Copulation Hemipenes Lizards Reproduction Reptiles

Nasopharyngeal colonization of otopathogens in South Indian children with acuteotitis media -- A case control pilot study

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journal of Otology 2021年第4期16卷 220-224页

作者： M.Napolean V.Rosemol M.john A.M.varghese j.Periyasamy V.Balaji P.Naina Department of ENT Christian Medical CollegeVelloreTamil NaduIndia Department of Clinical Microbiology Christian Medical CollegeVelloreIndia

Background: Acute otitis media (AOM) is an inflammatory disease of the middle ear causing significantmorbidity in early childhood. A pilot study was undertaken to identify the role of various risk factorsSouth Indian children with AOM, especially the role of nasopharyngeal ***: A prospective case control pilot study was conducted in children aged below six years,presenting to a single tertiary care from 2018 to 2019. Fifty cases with AOM and 45 age and gendermatched controls were recruited. Two nasopharyngeal swabs were collected, one was processed forbacterial culture. The other swab was processed according to the CDC recommended broth enrichmentmethod to identify carriage of S. pneumoniae. Subsequent serotyping was done by Quellung method andconventional sequential multiplex ***: Otalgia was the major presentation seen in 92% of the children with AOM. None of the clinical anddemographic characteristics were found to be statistically significant between the cases and controls. Themost common otopathogen was S. pneumoniae (55%) followed by H. influenza (29%). The commonS. pneumoniae serotypes encountered were 11A and *** colonization with S. pneumoniae[OR 6.57, p < 0.003] and H. influenzae [OR14.18, p < 0.003] were significant risk factors for AOM inchildren. The risk increased with co-colonization (OR 13.89,p < 0.003).Conclusion: This study strengthens the significant association between nasopharyngeal colonization ofotopathogens and AOM as a risk factor that is enhanced by co-colonization.S. pneumoniae was the mainotopathogen in this population, serotypes 11A and 19F being the most common.

关键词： Acute otitis media Nasopharyngeal Otopathogens Case control study Streptococcus pneumoniae Haemophilus influenzae Moraxella catarrhalis Staphylococcus aureus

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聚酯与人造丝混纺织物的树脂整理

国外纺织技术(化纤、染整、三废治理分册) 1981年第11期 21-23页

作者： j.varghese 张文光

1.引言目前棉纺厂已普遍使用化学纤维素纤维。人造丝混纺织物的湿加工需要特别注意。这些人造丝混纺织物有两种主要缺陷:(1) 尺寸稳定性很差;(2) 没有厚实丰满的手感。为了克服上述这些缺陷,可采用反应性类型树脂以及能赋予整理织物耐... 详细信息

1.引言目前棉纺厂已普遍使用化学纤维素纤维。人造丝混纺织物的湿加工需要特别注意。这些人造丝混纺织物有两种主要缺陷:(1) 尺寸稳定性很差;(2) 没有厚实丰满的手感。为了克服上述这些缺陷,可采用反应性类型树脂以及能赋予整理织物耐久硬挺度或身骨的添加剂。本研究试图对这些混纺织物进行树脂整理,采用各种树脂固着的技术,即用两种催化剂体系和湿固着处理的快速焙烘和轧一烘一焙工艺流程。本文报道了这方面的研究结果。

关键词：混纺织物撕破强度断裂强度混纺产品硬挺整理剂硬挺度树脂整理人造丝折皱回复性焙烘

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染色工艺对活性染料染棉织物性能的影响

国外纺织技术(化纤、染整、环境保护分册) 1987年第5期 23-25页

作者： j.varghese 王定国

在现行染整试验研究中,采用轧—烘—蒸(PDS)染色工艺,在固色时利用饱和蒸汽提高织物的湿度以达到增深成品色泽。在固色时PDS工艺,当湿度有限,存在少量的尿素有助于染料的溶解,促使染料在纤维材料中充分扩散,而导致染色织物得色量的提高... 详细信息

在现行染整试验研究中,采用轧—烘—蒸(PDS)染色工艺,在固色时利用饱和蒸汽提高织物的湿度以达到增深成品色泽。在固色时PDS工艺,当湿度有限,存在少量的尿素有助于染料的溶解,促使染料在纤维材料中充分扩散,而导致染色织物得色量的提高。牢度特性棉织物染色的各种牢度特性随使用的染

关键词：活性染料 PDS 染色工艺染色织物

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尿素在棉的一氯均三嗪染料热固染色中的作用

国外纺织技术(化纤、染整、环境保护分册) 1988年第3期 35-37页

作者： j.varghese S.K.Patel 邵竹峰

引言尿素是一种广泛用于棉织物染色、印花和整理中的常用助剂。在棉的热固染色中,它的作用主要是由于提高染料溶解度,并使纤维有较大的溶胀,使染料能更好地渗透,从而提高染料的固着。 Kissa认为,用乙烯砜染料以轧烘焙工艺对棉染色时,... 详细信息

引言尿素是一种广泛用于棉织物染色、印花和整理中的常用助剂。在棉的热固染色中,它的作用主要是由于提高染料溶解度,并使纤维有较大的溶胀,使染料能更好地渗透,从而提高染料的固着。 Kissa认为,用乙烯砜染料以轧烘焙工艺对棉染色时,在碱和热的存在下,尿素会促进这类染料/纤维键的裂解,从而减少活性

关键词：均三嗪棉织物染色染浴焙烘水洗牢度耐久压烫整理活性蓝染色织物纤维材料过硼酸钠

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纯棉织物和棉/粘混纺织物的树脂整理

国外纺织技术 1979年第5期 72-77页

作者： j.varghese B.A.DOSHI A.V.GTORE 印呜峪

一、引言在各种纤维素纤维当中,木棉粘胶纤维的物理和化学性质与棉最为接近,因此棉与高强度粘胶纤维的混纺已广泛地在印度使用。有文献指出,当粘胶成份超过33%的时候,棉/粘混纺织物的湿加工过程就必须十分小心,而且粘胶纤维的主要缺点... 详细信息

一、引言在各种纤维素纤维当中,木棉粘胶纤维的物理和化学性质与棉最为接近,因此棉与高强度粘胶纤维的混纺已广泛地在印度使用。有文献指出,当粘胶成份超过33%的时候,棉/粘混纺织物的湿加工过程就必须十分小心,而且粘胶纤维的主要缺点之一是在湿处理期间容易原纤化,因此棉/粘混

关键词：织物干态回潮率曲磨撕裂强度回弹性纤维性能粘胶人造纤维再生纤维素纤维粘胶纤维评分值树脂整理

人HCN4通道的滞后现象:影响窦房结起搏的潜在决定因素(英文)

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生理学报 2010年第1期62卷 1-13页

作者：萧永福 Natalie Chandler Halina Dobrzynski Eric S.Richardson Erica M.TenBroek joshua j.Wilhelm Vinod Sharma Anthony varghese Mark R.Boyett Paul A.Iaizzo Daniel C.Sigg 美敦力公司心脏节律疾病管理部曼彻斯特大学医学院明尼苏达州大学外科学系明尼苏达州大学整合生物学与生理学系美敦力公司科学技术部威斯康辛大学雷河分校计算机系

超极化活化环核苷酸门控(hyperpolarization-activated cyclic-nucleotide-gated,HCN)通道参与调制心脏跳动的节律和速率。与HCN1和HCN2有所不同,慢通道HCN4可能不存在电压依赖的滞后现象。本研究采用单细胞膜片钳方法,在稳定转染hHCN4... 详细信息

超极化活化环核苷酸门控(hyperpolarization-activated cyclic-nucleotide-gated,HCN)通道参与调制心脏跳动的节律和速率。与HCN1和HCN2有所不同,慢通道HCN4可能不存在电压依赖的滞后现象。本研究采用单细胞膜片钳方法,在稳定转染hHCN4的HEK293细胞上进行电生理记录,观察hHCN4通道是否存在滞后现象,以及cAMP对其的调制作用;同时采用实时定量RT-PCR方法检测窦房结和心房组织中HCNs的表达。电压钳实验结果显示hHCN4电流(Ih)激活随着保持电位超极化的变化而向去极化方向移动。三角电位变化钳(triangular ramp)和动作电位钳的结果也显示了hHCN4的滞后现象。cAMP增加Ih电流幅度,且使电流激活向去极化方向移动,从而改变内源性hHCN4滞后行为。RT-PCR结果显示,人窦房结组织主要表达HCN4,占75%,HCN1占21%,HCN2占3%,HCN3占0.7%。以上结果提示,人窦房结组织主要表达HCN4亚型,hHCN4的Ih存在电压依赖性的滞后现象,且受cAMP调制。由此推断,hHCN4通道的滞后现象可能在窦房结起搏活动中起到了关键作用。

关键词： HCN4通道滞后窦房结 cAMP

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自我监测血压和自我调整药物对合并高危心血管疾病的高血压患者收缩压的影响--脑卒中和高危人群血压控制目标和自我管理随机临床试验

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中华高血压杂志 2014年第11期22卷 1087-1088页

作者： McManus Rj Mant j Haque MS Bray EP Bryan S Greenfield SM jones MI jowett S Little P Penaloza C Schwartz C Shackleford H Shovelton C varghese j Williams B Hobbs FD 练桂丽叶鹏 unknown

血压升高是全球疾病负担的主要危险因素。虽然在过去10年中得到了改善,但是血压控制率仍然很低。修订后的美国高血压预防、检测、评估与治疗联合委员会（the joint national committee on prevention,detection,evaluation,and treatmen... 详细信息

血压升高是全球疾病负担的主要危险因素。虽然在过去10年中得到了改善,但是血压控制率仍然很低。修订后的美国高血压预防、检测、评估与治疗联合委员会（the joint national committee on prevention,detection,evaluation,and treatment of high blood pressure,jNC）专家组成员第8次报告（jNC8）2014年高血压循证管理指南提出≥60岁的老年人,糖尿病和慢性肾脏病患者血压的控制目标可以放宽。目前接受高血压治疗的美国人达到血压控制目标的比例,

关键词：血压控制目标高血压患者高危心血管疾病随机临床试验自我管理高危人群自我调整 prevention

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Hepatitis B virus subgenotype A1 predominates in liver disease patients from Kerala,India

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World journal of Gastroenterology 2013年第48期19卷 9294-9306页

作者： Deepak Gopalakrishnan Mark Keyter Kotacherry Trivikrama Shenoy Kondarappassery Balakumaran Leena Lakshmikanthan Thayumanavan varghese Thomas KR Vinayakumar Charles Panackel Arun T Korah Ramesh Nair Anna Kramvis Hepatitis Virus Diversity Research Programme Department of Internal Medicine School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Parktown Johannesburg 2193 South Africa Department of Gastroenterology Medical College Trivandrum 695011 India Population Health and Research Institute Trivandrum 695011 India Government Rajaji Hospital Madurai Medical College Madurai 625002 India Department of Gastroenterology Calicut Medical College PO Calicut 673008 India

AIM:To molecularly characterize hepatitis B virus(HBV)isolates from Kerala and to relate them to the clinical manifestation of ***:Sera and clinical data were collected from91 patients diagnosed with chronic HBV infection and HBV-related hepatocellular carcinoma(HCC).HBV from44 HCC,22 cirrhotic and 25 chronic hepatitis patients were genotyped by sequencing of the complete S region or by restriction fragment length polymorphism *** basic core promoter/precore region was *** complete surface DNA sequences were assembled and aligned manually,and then compared with the sequences of HBV of genotypes(A-j)from *** evolutionary history was inferred using the Neighbor-joining method and the evolutionary distances computed using the Kimura 2-parameter *** was performed using 1000 *** TaqMan BS-1 probe was used to quantify HBV DNA at a lower detection limit of approximately20 IU/*** variables were compared using an independent Student’s t ***χ2test or Fisher’s exact test was used to compare categorical *** differences were considered statistically significant at P<***:Irrespective of disease status,the predominant genotype was A(72%);95%belonging to subgenotype A1,followed by genotypes D(27%)and C(1%).HCC patients infected with subgenotype A1were significantly younger than those infected with *** A1762T/G1764A was significantly associated with HCC in both genotypes A and *** G1862T was more frequent in subgenotype A1(P<0.0001),and in combination with A1762T/G1764A,it was significantly associated with HBV from HCC *** C1766T/T1768A was significantly associated with genotype A(P=0.05)and HCC(P=0.03).The preS2start codon M1T/I mutation was unique to genotype A strains(15.6%)from all disease groups and occurred at a higher frequency in isolates from HCC patients(P=0.076).A higher frequency of preS deletion mutants(33.3%)was observed in genotype A from HC

关键词： Hepatocellular carcinoma Cirrhosis Chronic hepatitis Phylogenetic analysis Genotype India