Catheter-based renal sympathetic nerve denervation on hypertension management outcomes

作     者：Som P Singh Kevin J Varghese Fahad M Qureshi Macy C Anderson John Foxworth Mark M Knuepfer 

作者机构：Department of Internal MedicineUniversity of Missouri Kansas City School of MedicineKansas CityMO 64106United States Department of Pharmacological and Physiological ScienceSaint Louis University School of MedicineSaint LouisMO 63104United States 

出 版 物：《World Journal of Radiology》 (世界放射学杂志（英文版）（电子版）)

年 卷 期：2022年第14卷第7期

页      面：238-248页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Renal denervation Hypertension Systematic review Interventional radiology Outcomes 

摘      要：BACKGROUND Renal sympathetic denervation(RSD)provides a minimally invasive interventional treatment modality for patients with resistant ***,the post-operative outcomes remain a key area of investigation since its earliest clinical *** To evaluate patient outcomes after RSD intervention among peer-reviewed patient *** A systematic review of literature on MEDLINE,Google Scholar,and the Cochrane Database of Systematic Reviews for RSD case studies to assess post-operative hypertension readings and medical *** Among 51 RSD cases,the post-operative RSD patients report an apparent reduction with a mean number of 3.1 antihypertensive *** mean systolic arterial blood pressure 1 year following RSD was 136.0 mmHg(95%CI:118.7-153.3).CONCLUSION The apparent improvements in office systolic blood pressure after 12 month postoperative RSD can support the therapeutic potential of this intervention for blood pressure *** studies which utilized a uniform methodology for blood pressure measurement can further support the findings of this systematic review.