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The Role of Public Health Within the United Nations Post-2015 Framework for Disaster Risk Reduction

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International Journal of Disaster Risk Science 2015年第1期6卷 28-37页

作者： Virginia Murray Amina Aitsi-Selmi kevin blanchard Public Health Strategy Division Public Health England

This article explores the role of public health systems before, during, and after disasters, particularly within the scope of the United Nations Post-2015 Framework for Disaster Risk Reduction. It also examines the role of scientific and technological developments in assisting with improving the resilience of public health professionals and the communities they work in. In addition, it explores how the wide-ranging activities in public health have already contributed to the improved management of disasters and a decrease in associated risks. The article identifies areas of synergy in five key areas of recent policy and practice in public health(the health systems approach, risk assessments, the WHO/UNISDR/HPA Disaster Risk Management fact sheets, chronic disease and disasters, and mental health impacts following disasters) and makes suggestions based on lessons identified from the previous(2005) global disaster risk reduction framework. In particular, we advocate the use of scientific evidence that addresses health and disaster risk simultaneously to increase the effectiveness of policy and practice in disaster risk reduction, health, and public health.

关键词： Disaster risk reduction Health systems Post-2015 framework Public health Risk assessments

The Sendai Framework for Disaster Risk Reduction and Its Indicators——Where Does Health Fit in?

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International Journal of Disaster Risk Science 2017年第2期8卷 150-155页

作者： Rishma Maini Lorcan Clarke kevin blanchard Virginia Murray Public Health Registrar in Global Disaster Risk Reduction Public Health England Research Analyst Intern in Global Disaster Risk Reduction Public Health England Senior Environmental Scientist in Global Disaster Risk Reduction Public Health England Public Health Consultant in Global Disaster Risk Reduction Public Health England United Nations International Strategy for Disaster ReductionScientific and Technical Advisory Group Integrated Research on Disaster Risk Reduction Scientific Committee

The Sendai Framework for Disaster Risk Reduction 2015–2030 recognizes the strong connection between health and disasters and promotes the concept of health resilience *** of the seven global targets stated in the Sendai Framework are directly related to health in terms of reducing disaster mortality,the number of affected people,disaster damage to critical infrastructure,and disruption of basic services such as health *** Sendai Framework also maintains close coordination with other United Nations landmark agreements relevant to health such as the Sustainable Development ***,the measurement of healthrelated indicators is *** arise,for example,in linking deaths to disasters because of the complex interplay between exposure,risk,vulnerability,and *** lack of a universal classification of disasters also means that recording of health data in disasters is not *** the guidelines to enable data onthe indicators to be collected and reported to support the Sendai targets requires detailed thinking,time,and consultation with a diverse range of *** collaboration and partnership will be vital to achieving success.

关键词： Disaster risk reduction Global health targets Health indicators Sendai Framework

Challenges with Disaster Mortality Data and Measuring Progress Towards the Implementation of the Sendai Framework

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International Journal of Disaster Risk Science 2019年第4期10卷 449-461页

作者： Helen K.Green Oliver Lysaght Dell D.Saulnier kevin blanchard Alistair Humphrey Bapon Fakhruddin Virginia Murray Global Disaster Risk Reduction Public Health EnglandLondon SE18UGUK Department of Public Health Sciences Karolinska Institutet17177 StockholmSweden Canterbury District Health Board Christchurch 8140New Zealand Disaster Risk Reduction and Climate Resilience Tonkin+TaylorAuckland 1141New Zealand

Disasters exact a heavy toll ***,the degree to which we can accurately quantify their impact,in particular mortality,remains *** is critical to ensure that disaster data reliably reflects the scale,type,and distribution of disaster impacts given the role of data in:(1)risk assessments;(2)developing disaster risk management programs;(3)determining the resources for response to emergencies;(4)the types of action undertaken in planning for prevention and preparedness;and(5)identifying research *** Sendai Framework for Disaster Risk Reduction 2015–2030 s seven global disaster-impact reduction targets represent the first international attempt to systematically measure the effectiveness of disaster-impact reduction as a means of better informing policy with *** A of the Sendai Framework aims to‘‘substantially reduce global disaster mortality by 2030,aiming to lower the average per 100,000 global mortality rate in the decade 2020–2030 compared to the period 2005–2015.’’This article provides an overview of the complexities associated with defining,reporting,and interpreting disaster mortality data used for gauging success in meeting Target A,acknowledging different challenges for different types of hazard events and subsequent *** concludes with suggestions of how to address these challenges to inform the public health utility of monitoring through the Sendai Framework.

关键词： Data Disaster mortality Disaster risk management Disaster risk reduction Mass casualty Sendai Framework

Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease

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Neural Regeneration Research 2025年第6期20卷 1644-1664页

作者： Gabriela Seplovich Yazan Bouchi Juan Pablo de Rivero Vaccari Jennifer C.Munoz Pareja Andrew Reisner Laura Blackwell Yehia Mechref kevin K.Wang J.Adrian Tyndall Binu Tharakan Firas Kobeissy Department of Surgery Morehouse School of MedicineAtlantaGAUSA Department of Neurobiology Center for NeurotraumaMultiomics&Biomarkers(CNMB)Neuroscience InstituteMorehouse School of MedicineAtlantaGAUSA Department of Neurological Surgery and the Miami Project to Cure Paralysis University of Miami Miller School of MedicineMiamiFLUSA Division of Pediatric Critical Care Department of PediatricsUniversity of Miami Miller School of MedicineMiamiFLUSA Department of Pediatrics Emory UniversityAtlantaGAUSA Department of Neurosurgery Children’s Healthcare of AtlantaAtlantaGAUSA Department of Chemistry and Biochemistry Texas Tech UniversityLubbockTXUSA Morehouse School of Medicine AtlantaGAUSA

Traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease are three distinct neurological disorders that share common pathophysiological mechanisms involving neuroinflammation. One sequela of neuroinflammation includes the pathologic hyperphosphorylation of tau protein, an endogenous microtubule-associated protein that protects the integrity of neuronal cytoskeletons. Tau hyperphosphorylation results in protein misfolding and subsequent accumulation of tau tangles forming neurotoxic aggregates. These misfolded proteins are characteristic of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease and can lead to downstream neuroinflammatory processes, including assembly and activation of the inflammasome complex. Inflammasomes refer to a family of multimeric protein units that, upon activation, release a cascade of signaling molecules resulting in caspase-induced cell death and inflammation mediated by the release of interleukin-1β cytokine. One specific inflammasome, the NOD-like receptor protein 3, has been proposed to be a key regulator of tau phosphorylation where it has been shown that prolonged NOD-like receptor protein 3 activation acts as a causal factor in pathological tau accumulation and spreading. This review begins by describing the epidemiology and pathophysiology of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease. Next, we highlight neuroinflammation as an overriding theme and discuss the role of the NOD-like receptor protein 3 inflammasome in the formation of tau deposits and how such tauopathic entities spread throughout the brain. We then propose a novel framework linking traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease as inflammasomedependent pathologies that exist along a temporal continuum. Finally, we discuss potential therapeutic targets that may intercept this pathway and ultimately minimize long-term neurological decline.

关键词： Alzheimer's disease caspase-1 chronic traumatic encephalopathy inflammasomes neurodegeneration neuroinflammation NLRP1 NLRP3 pyroptosis tauopathy traumatic brain injury

A thermodynamic perspective on electrode poisoning in solid oxide fuel cells

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International Journal of Minerals,Metallurgy and Materials 2024年第6期31卷 1449-1455页

作者： kevin Huang Department of Mechanical Engineering University of South CarolinaColumbiaUSA

A critical challenge to the commercialization of clean and high-efficiency solid oxide fuel cell(SOFC)technology is the insuf-ficient stack lifespan caused by a variety of degradation mechanisms,which are associated with cell components and chemical *** components related degradation refers to thermal/chemical/electrochemical deterioration of cell materials under operating conditions,whereas the latter regards impurities in feedstocks of oxidant(air)and reductant(fuel).This article provides a thermodynamic perspective on the understanding of the impurities-induced degradation mechanisms in *** discussion focuses on using thermodynamic ana-lysis to elucidate poisoning mechanisms in cathodes by impurity species such as Cr,CO_(2),H_(2)O,and SO_(2) and in the anode by species such as S(or H_(2)S),SiO_(2),and P_(2)(or PH_(3)).The author hopes the presented fundamental insights can provide a theoretical foundation for search-ing for better technical solutions to address the critical degradation challenges.

关键词： impurities air fuel reaction activity

Mixed ion and electron transport theory and application in solid oxide conductors

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International Journal of Minerals,Metallurgy and Materials 2022年第4期29卷 870-875页

作者： kevin Huang Department of Mechanical engineering University of South CarolinaColumbiaSC 292201USA

Mixed ions and electron conductors(MIECs)are an important family of electrocatalysts for electrochemical devices,such as reversible solid oxide cells,rechargeable metal-air batteries,and oxygen transport *** ionic and electronic transports in these materials play a key role in electrocatalytic *** in-depth fundamental understanding of the transport phenomena is critically needed to develop better *** this brief review,we introduced generic ionic and electronic transport theory based on irreversible thermodynamics and applied it to practical oxide-based materials with oxygen vacancies and electrons/holes as the predominant *** oxide systems,namely CeO_(2)-based and La CrO_(3)-based materials,are selected as case studies to illustrate the utility of the transport theory in predicting oxygen partial pressure distribution across MIECs,electrochemical electronic/ionic leakage currents,and the effects of external load current on the leakage currents.

关键词： irreversible thermodynamics diffusivity charge neutrality electrochemical potential electrostatic potential

Multistage Off-Line Permutation Packet Routing on a Mesh:An Approach with Elementary Mathematics

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Journal of Computer Science & Technology 2009年第1期24卷 175-180页

作者： kevin Chiew School of Information Systems Singapore Management University80 Stamford RoadSingapore 178902

Various methods have been proposed for off-line permutation packet routing on a mesh. One of the methods is known as multistage routing, in which the first stage is crucial. For the first stage of routing, the previous study normally converts it to a problem of graph theory and proves the existence of solutions. However, there is a lack of simple algorithms to the first stage of routing. This article presents an explicit and simple approach for the first stage of routing based on elementary mathematics.

关键词： permutation packet routing explicit algorithm

Determination of contact parameters for discrete element method simulations of granular systems

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Particuology 2008年第6期6卷 521-528页

作者： kevin Francis Malone Institute of Particle Science and Engineering University of Leeds

Both linear-spring-dashpot （LSD） and non-linear Hertzian-spring-dashpot （HSD） contact models are commonly used for the calculation of contact forces in Discrete Element Method （DEM） simulations of granular systems. Despite the popularity of these models, determination of suitable values for the contact parameters of the simulated particles such as stiffness, damping coefficient, coefficient of restitution, and simulation time step, is not altogether obvious. In this work the relationships between these contact parameters for a model system where a particle impacts on a flat base are examined. Recommendations are made concerning the determination of these contact parameters for use in DEM simulations.

关键词： Discrete Element Method (DEM) Linear-spring--dashpot model Non-linear Hertzian-spring-dashpot model Contact parameters

Interdependence of friction, wear, and noise: A review

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Friction 2021年第6期9卷 1319-1345页

作者： kevin LONTIN Muhammad KHAN Cranfield University MK430ALUK

Phenomena of friction,wear,and noise in mechanical contacts are particularly important in the field of tribomechanics but equally complex if one wants to represent their exact relationship with mathematical *** have been made to describe these phenomena with different approaches in *** efforts have been compiled in different reviews but most of them treated friction,wear mechanics,and acoustic noise ***,an in-depth review that provides a critical analysis on their interdependencies is still *** this review paper,the interdependencies of friction,wear,and noise are analysed in the mechanical contacts at asperitical *** origin of frictional noise,its dependencies on contact’s mechanical properties,and its performance under different wear conditions are critically reviewed.A discussion on the existing mathematical models of friction and wear is also provided in the last section that leads to uncover the gap in the existing *** review concludes that still a comprehensive analytical modelling approach is required to relate the interdependencies of friction,noise,and wear with mathematical expressions.

关键词： noise acoustic emission wear friction