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Like mother. like daughter. her.tability of female r.char.son＇s gr.und squir.el Ur.citellus r.char.sonii cor.isol str.ss r.sponses

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Cur.ent Zoology 2018年第2期64卷 153-163页

作者： kevin r. bairos-novak Calen r.r.AN Angela r. Fr.EMAN W. Gar. ANDEr.ON James F, HAr. Depar.ment of Biological Sciences University of Manitoba Winnipeg Manitoba R3T 2N2 Canada Depar.mentof Biology University of Saskatchewan Saskatoon S7N 5E2 Saskatchewan Canada Depar.ment ofAnthr.pology Northwestern University Evanston 60208 Illinois USA Depar.ment of Biological Sciences Kent State University Kent 44242 Ohio USA

Activation of the hypothalamic-pituitar.-adr.nal （HPA） axis liber.tes glucocor.icoids, which pr.vides an acute indication of an individual＇s r.sponse to str.ssor.. The her.tability of the str.ss r.sponse in wild mammals, however. r.mains poor.y documented. We quantified the cor.isol str.ss r.sponse of female r.char.son＇s gr.und squir.els （r.Ss） to handling and physical r.str.int, testing for. （1） the effects of individual age, time of day, and sample latency; （2） r.peatability within individuals; （3） nar.ow-sense her.tability; and （4） differ.nces among individuals owing to potential genetic and/or.envir.nmental effects. We detected a positive linear.r.lationship between baseline plasma cor.isol （BL-cor.isol） concentr.tion and str.ss-induced plasma cor.isol （Sl-cor.isol） concentr.tion that defined each individual＇s cor.isol str.ss r.sponse. BL-cor.isol, SI-cor.isol, and str.ss r.sponse did not differ.accor.ing to the time the sample was taken, or.by subject age. Cor.isol str.ss r.sponse was highly r.peatable within individuals, had a mother.offspr.ng her.tability of h2 =0.40 ± 0.24 （mean ±SE）, full-sibling her.tability of h2s = 0.37 ± 0.71, and half-sibling her.tabil- ity of hHS^2 = 0.75 ± 1.41. Str.ss r.sponses of sibling gr.ups, immediate-family gr.ups, and squir. r.ls within a given ar.a did not differ. wher.as those of individuals fr.m mor. distantly r.lated matr.lines did. Our.r.sults highlight the natur.l var.ability in HPA axis r.activity among individuals by quantifying both BL- and SI-cor.isol levels, demonstr.te par.ial her.tability of the str.ss r.sponse that is not attr.butable to envir.nmental var.ation, and suggest that at least par. of an indi- vidual＇s str.ss r.sponse can be accounted for.by differ.nces in matr.lineal histor..

关键词： glucocor.icoids gr.und squir.el her.tability hypothalamic-pituitar.-adr.nal axis r.activity str.ss r.sponse.

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A ther.odynamic per.pective on electr.de poisoning in solid oxide fuel cells

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Inter.ational Jour.al of Miner.ls,Metallur.y and Mater.als 2024年第6期31卷 1449-1455页

作者： kevin Huang Depar.ment of Mechanical Engineer.ng University of South CarolinaColumbiaUSA

A cr.tical challenge to the commer.ialization of clean and high-efficiency solid oxide fuel cell(SOFC)technology is the insuf-ficient stack lifespan caused by a var.ety of degr.dation mechanisms,which ar. associated with cell components and chemical *** components r.lated degr.dation r.fer. to ther.al/chemical/electr.chemical deter.or.tion of cell mater.als under.oper.ting conditions,wher.as the latter.r.gar.s impur.ties in feedstocks of oxidant(air.and r.ductant(fuel).This ar.icle pr.vides a ther.odynamic per.pective on the under.tanding of the impur.ties-induced degr.dation mechanisms in *** discussion focuses on using ther.odynamic ana-lysis to elucidate poisoning mechanisms in cathodes by impur.ty species such as Cr.CO_(2),H_(2)O,and SO_(2) and in the anode by species such as S(or.H_(2)S),SiO_(2),and P_(2)(or.PH_(3)).The author.hopes the pr.sented fundamental insights can pr.vide a theor.tical foundation for.sear.h-ing for.better.technical solutions to addr.ss the cr.tical degr.dation challenges.

关键词： impur.ties air fuel r.action activity

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Integr.ted photonic fr.ctional convolution acceler.tor

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Photonics r.sear.h 2024年第8期12卷 1828-1839页

作者： kevin ZELAYA MOHAMMED-ALI MIr. Depar.ment of Physics Queens College of the City University of New YorkQueensNew York 11367USA Physics Pr.gr.m The Graduate Center of the City University of New YorkNew YorkNew York 10016USA

An integr.ted photonic cir.uit ar.hitectur. to per.or. a modified-convolution oper.tion based on the discr.te fr.ctional Four.er.tr.nsfor.(DFr.T) is intr.duced. This is accomplished by utilizing two nonunifor.ly coupled waveguide lattices with equally spaced eigenmode spectr., the lengths of which ar. chosen so that the DFr.T and its inver.e oper.tions ar. achieved. A pr.gr.mmable modulator.ar.ay is inter.aced so that the r.quir.d fr.ctional convolution oper.tion is per.or.ed. Numer.cal simulations demonstr.te that the pr.posed ar.hitectur. can effectively per.or. smoothing and edge detection tasks even for.noisy input signals, which is fur.her.ver.fied by electr.magnetic wave simulations. Notably, mild lattice defects do not jeopar.ize the ar.hitectur. per.or.ance, showing its r.silience to manufactur.ng er.or..

关键词： fr.ctional convolution utilizing

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Speed and sur.ace steepness affect inter.al tibial loading dur.ng r.nning

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Jour.al of Spor. and Health Science 2024年第1期13卷 118-124页

作者： Hannah r.ce Mar.us Kur. Patr.ck Mai Leon r.ber.z kevin Bill Timothy r.Der.ick Steffen Willwacher Depar.ment of Physical Per.or.ance Norwegian School of Sport SciencesOslo 0806Norway Spor.s Tech r.sear.h Centr. Mid Sweden UniversityÖstersund SE-83125Sweden Depar.ment of Mechanical and Pr.cess Engineer.ng Offenburg University of Applied SciencesOffenburg 77652Germany Institute of Biomechanics and Or.hopaedics German Sport University CologneCologne 50933Germany Depar.ment of Kinesiology Iowa State UniversityAmesIA 50011USA

Backgr.und:Inter.al tibial loading is influenced by modifiable factor. with implications for.the r.sk of str.ss *** encounter.var.ed sur.ace steepness(gr.dients)when r.nning outdoor. and may adapt their.speed accor.ing to the *** study aimed to quantify tibial bending moments and str.ss at the anter.or.and poster.or.per.pher.es when r.nning at differ.nt speeds on sur.aces of differ.nt ***:Twenty r.cr.ational r.nner. r.n on a tr.admill at 3 differ.nt speeds(2.5 m/s,3.0 m/s,and 3.5 m/s)and gr.dients(level:0%;uphill:+5%,+10%,and+15%;downhill:-5%,-10%,and-15%).For.e and mar.er.data wer. collected synchr.nously *** moments wer. estimated at the distal thir. centr.id of the tibia about the medial-later.l axis by ensur.ng static equilibr.um at each 1%of *** was der.ved fr.m bending moments at the anter.or.and poster.or.per.pher.es by modeling the tibia as a hollow ***-way r.peated-measur.s analysis of var.ance wer. conducted using both functional and discr.te statistical ***:Ther. wer. significant main effects for.r.nning speed and gr.dient on peak bending moments and peak anter.or.and poster.or.*** r.nning speeds r.sulted in gr.ater.tibial *** uphill at+10%and+15%r.sulted in gr.ater.tibial loading than level *** downhill at-10%and-15%r.sulted in r.duced tibial loading compar.d to level *** was no differ.nce between+5%or.5%and level ***:r.nning at faster.speeds and uphill on gr.dients≥+10%incr.ased inter.al tibial loading,wher.as slower.r.nning and downhill r.nning on gr.dients≥-10%r.duced inter.al *** r.nning speed accor.ing to the gr.dient could be a pr.tective mechanism,pr.viding r.nner. with a str.tegy to minimize the r.sk of tibial str.ss injur.es.

关键词： Bending moments Gr.dient Musculoskeletal modeling Over.se injur. Tibial str.ss Tr.ining factor.

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r.dent biology and ecologically based r.dent management(EBr.)-25 year. of pr.gr.ss thr.ugh pr.moting multidisciplinar. r.sear.h

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Integr.tive Zoology 2024年第1期19卷 2-7页

作者： Gr.nt r. SINGLETON Lyn A. HINDS r.odes MAKUNDI Steven r. BELMAIN Natur.l r.sour.es Institute University of Greenwich Kent UK CSIr. Health and Biosecur.ty Canberra ACT Australia Afr.can Centr. of Excellence for.Innovative r.dent Pest Management and Biosensor.Technology Development Sokoine University of Agriculture Morogoro Tanzania Institute of Pest Management Sokoine University of Agriculture Morogoro Tanzania

“Dur.ng r.dent outbr.ak year. in easter. Afr.ca,lo-cally,mor. than 80%of the potential har.est may be lost,but even in non-outbr.ak per.ods,r.dents cause chr.nic damage to cr.ps….The pest r.dent stor. in Afr.ca in-volves sever.l species embedded in a br.ad and var.able landscape with highly var.able densities.”(Leir. et al.2010).

关键词： damage cr.ps

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Neur.n-to-astr.cyte pr.teostatic str.ss signaling in r.sponse to tau pathology

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Neur.l r.gener.tion r.sear.h 2024年第3期19卷 505-506页

作者： kevin Llewelyn Batenbur. Wiep Scheper Amster.am UMC location Vr.je Univer.iteit Amster.am Department of Human GeneticsAmsterdam Neuroscience-NeurodegenerationAmsterdamThe Netherlands Depar.ment of Functional Genomics Center for Neurogenomics and Cognitive ResearchVrije Universiteit AmsterdamAmsterdam Neuroscience-NeurodegenerationAmsterdamThe Netherlands

Maintenance of pr.tein homeostasis or.pr.teostasis”is essential for.the functioning and viability of *** is in par.icular.the case for.cells like neur.ns that cannot self-r.new and acquir. unique functional pr.per.ies dur.ng their.*** pr.teostatic str.ss r.sponses ar. in place to pr.tect cells fr.m damage in case of pr.teostatic *** integr.ted str.ss r.sponse(ISr.is one of the key pr.teostatic str.ss r.sponses in the cell(Costa-Mattioli and Walter.2020).The ISr.is the downstr.am conver.ence point for.the four.str.ss-induced eIF2αkinases(EIF2AK1-4)that contr.l str.ss-r.gulated pr.tein tr.nslation via phosphor.lation of the tr.nslation factor.eIF2α.ISr.activation r.sults in a tr.nsient r.duction of global tr.nslation while it concomitantly enhances the tr.nslation of specific mr.As,including that encoding the activating tr.nscr.ption factor.4(ATF4).Together.the tr.nslational contr.l mediated by the ISr.r.sults in a tempor.r. r.duction of the over.ll pr.tein load and the selectively incr.ased expr.ssion of pr.teins that contr.bute to r.stor.tion of the pr.teostatic balance.

关键词： tr.nslation str.ss Together

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High temper.tur. defor.ation and r.cr.stallization behavior.of magnesium bicr.stals with 90°<1010>and 90°<1120>tilt gr.in boundar.es

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Jour.al of Magnesium and Alloys 2024年第2期12卷 625-638页

作者： kevin Bissa Talal Al-Samman Dmitr. A.Molodov Institute of Physical Metallur.y and Mater.als Physics RWTH Aachen University52056 AachenGermany Inter.ational r.sear.h Or.anization for.Advanced Science and Technology(Ir.AST) Kumamoto UniversityKumamoto 860-8555Japan

The defor.ation mechanisms and dynamic r.cr.stallization(Dr.)behavior.of specifically gr.wn bicr.stals with a symmetr.c 90°and 90°tilt gr.in boundar.,r.spectively,wer. investigated under.defor.ation in plane str.in compr.ssion at 200℃and 400℃.The micr.str.ctur.s wer. analyzed by panor.mic optical micr.scopy and lar.e-ar.a electr.n backscatter.diffr.ction(EBSD)or.entation *** analysis employed a meticulous appr.ach utilizing hundr.ds of individual,small EBSD maps with a small step size that wer. stitched together.to pr.vide compr.hensive access to or.entation and misor.entation data on a macr.scopic *** slip pr.mar.ly gover.ed the ear.y stages of defor.ation at the two temper.tur.s,and the r.sulting shear.induced lattice r.tation ar.und the tr.nsver.e dir.ction(TD)of the *** existence of the gr.in boundar. gave r.se to dislocation pile-up in its vicinity,leading to much lar.er.TD-lattice r.tations within the boundar. r.gion compar.d to the *** incr.asing temper.tur.,the defor.ation was gener.lly mor. unifor. towar.s the bulk due to enhanced dislocation mobility and mor. unifor. str.ss *** r.cr.stallization at 200℃was initiated in{1011}-compr.ssion twins at str.ins of 40%and *** 400℃,Dr. consumed the entir. gr.in boundar. r.gion and gr.dually r.placed the defor.ed micr.str.ctur. with pr.gr.ssing *** r.cr.stallized gr.ins displayed char.cter.stic or.entations,such that their.c-axes wer. per.endicular.to the TD and additionally scatter.d between 0°and 60°fr.m the loading *** r.cr.stallized gr.ins displayed mutual r.tations of up to 30°ar.und the c-axes of the initial gr.ins,for.ing a discer.ible basal fiber.textur. component,pr.minently visible in the{1120}pole *** is notewor.hy that the defor.ation and Dr. behavior. of the two analyzed bicr.stals exhibited mar.inal var.ations in r.sponse to str.in and defor.ation temper.tur..

关键词： Elevated defor.ation temper.tur.s Plain str.in compr.ssion Magnesium bicr.stals Panor.ma EBSD Dynamic r.cr.stallization

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Why the Conver.ion of Hydr.gen H_(2)Is Still-or.Mor. Than Ever.Delayed

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Management Studies 2024年第4期12卷 218-224页

作者： David novak DIPLOMA Univer.ity of Applied Sciences Germany FHM Univer.ity of Small and Medium Enter.r.ses and Inter.ational Univer.ity Germany

Numer.us decision-maker. in politics,science,and business wor.dwide have acknowledged that hydr.gen H_(2) will become one of the most impor.ant ener.y sour.es of the 21st centur. if the desir.d ener.y tr.nsition to car.on-fr.e ener.y sour.es is to be taken ***,this tr.nsition in gener.l and the intr.duction of H_(2) in par.icular.is still pr.gr.ssing far.too *** ar. now countless pr.jects wor.dwide,including sever.l wor.h billions of US dollar.,but we ar. still waiting for.the *** seem to be var.ous r.asons for.this,not just one single or.most impor.ant ***:In the over.ll context of global ear.h over.eating(often downplayed as“climate change”),hydr.gen H_(2) will undoubtedly play a decisive r.le as of *** paper.aims to identify the key challenges and pr.pose solutions for.establishing a sustainable value chain for.mar.et penetr.tion of H_(2).Design/methodology/appr.ach:This paper.aims to shed light on the cur.ent situation using fr.ely accessible publications fr.m global management consultancies and the Ger.an gover.ment,as well as cr.tical *** pr.blem of human behavior.is also explained by the novak ***:Most people have come to under.tand that anthr.pogenic global over.eating can only be solved by new technologies(which cost money,time,and behavior.l change)in pr.duction and *** H_(2) appear. to be an essential par. of the desir.d ***,ther. ar. cur.ently still numer.us challenges and also concr.te concer.s wor.dwide,which par.ially cast the implementation in a questionable *** findings suggest that establishing a demand and supply of H_(2) needs a compr.hensive infr.str.ctur.,cir.ular.economy pr.nciples,and changes in consumer.behavior.and policy *** paper.pr.poses solutions for.addr.ssing these *** countr.es:The situation descr.bed her. r.lates to Ger.any and the EU countr.es,but it is likely to be compar.ble,or.at leas

关键词： global ear.h over.eating hydr.gen H_(2) novak Tr.angle-Motivation/Decision Making for.People to Act

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Or.hogonal polynomial expansions for.the valuation ofoptions under.the stochastic volatility models with stochastic cor.elation

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Jour.al of Management Science and Engineer.ng 2024年第2期9卷 239-253页

作者： kevin Z.Tong Depar.ment of Mathematics and Statistics University of Ottawa585 King EdwardOttawaOntarioK1N 6N5Canada

This wor. pr.vides a new method for.pr.cing options under.the gener.lized stochastic volatility models with Jacobi stochastic *** method is based on the obser.ation that the gener.lized models belong to the class of polynomial diffusions and ther.for. the option pr.ces can be efficiently computed via or.hogonal polynomial *** take the Heston and Schöbel-Zhu models with stochastic cor.elation as two specific examples and ar. able to der.ve the analytical for.ulas for.the option *** also illustr.te the accur.cy of the pr.posed method thr.ugh a number.of numer.cal exper.ments.

关键词： Or.hogonal polynomial expansions Polynomial diffusions Stochastic cor.elation Jacobi pr.cess Stochastic volatility

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Neur.lithogr.phy:Lithogr.phy as an enabling technology in neur.logy and neur.science

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Medicine in Novel Technology and Devices 2024年第2期22卷 15-18页

作者： kevin Zhai Depar.ment of Medical Education Weill Cornell Medicine-QatarP.O.Box 24144DohaQatar

Moder. lithogr.phy,which enables the fabr.cation of complex str.ctur.s in biomedical devices with exceptional pr.cision,is a potentially tr.nsfor.ative for.e in the neur.l *** such as photolithogr.phy,electr.n beam lithogr.phy,and soft lithogr.phy have been utilized to pr.duce devices that guide neur.nal gr.wth and differ.ntiation and measur. electr.physiological signals at the single-cell *** the clinical spher.,lithogr.phy plays a r.le in the manufactur.ng of devices for.deep br.in stimulation,br.in-computer.inter.ace,and ***,we br.efly r.view the applications of lithogr.phy in basic and tr.nslational neur.science and clinical neur.logy,with an eye towar. futur. advancement.

关键词： Lithogr.phy Neur.lithogr.phy Semiconductor. Micr.fluidics Neur.l devices

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