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Does the intracoronary pressure differ according to two types(diffuse or focal)of coronary spasm?

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World Journal of Cardiology 2023年第1期15卷 1-12页

作者： Hiroki Teragawa Chikage Oshita Yuko uchimura Department of Cardiovascular Medicine JR Hiroshima HospitalHiroshima 732-0057Japan

BACKGROUND Several reports show that two types of coronary vasospasm(diffuse and focal spasm)are associated with the severity or prognosis of coronary spasm in patients with vasospastic angina(VSA).It is unclear whether intracoronary pressure differs between the two spasm *** To investigate such relationships using a pressure wire during the spasm provocation test(SPT)in patients with *** Eighty-seven patients with VSA(average age:67 years;50 men,37 women)underwent *** the SPT,a pressure wire was advanced into the distal portion of the right coronary artery and left anterior descending coronary artery,and the ratio of the intracoronary pressure to the aortic pressure(Pd/Pa)was continuously *** SPT was performed using acetylcholine(ACh),and the presence of coronary spasm was defined as the presence of>90%arterial narrowing in response to an ACh infusion,with the usual chest symptoms and/or ischemic ECG *** spasm was defined as total or subtotal spasm within one segment of the AHA classification,while diffuse spasm was defined as>90%spasm with two or more *** Among 87 patients,the frequencies of metabolic syndrome and having coronary atherosclerosis were higher in the focal group(n=33)than in the diffuse spasm group(n=54,P<0.05).In the vessel analyses,in these 134 spastic segments,diffuse and focal spasms were detected in 100 and 34 vessels,*** Pd/Pa at baseline was similar in both groups(diffuse:0.96±0.05,focal:0.95±0.05,P=0.35);however,the Pd/Pa during coronary spasm was lower in focal spastic vessels(0.66±0.20)than in diffuse spastic vessels(0.76±0.11,P<0.01),and the reduction in Pd/Pa during an SPT was also lower in focal spastic vessels(-0.29±0.20)than in diffuse spastic vessels(-0.18±0.11,P<0.01).The presence of focal spasm was a significant factor responsible for reduction in Pd/Pa during *** These findings suggest that focal spasm may be more severe than diffuse spasm,judging from the

关键词： Acetylcholine Intracoronary pressure Diffuse or focal spasm Vasospastic angina

Do changes in intracoronary pressure aid coronary spasm diagnosis using the spasm provocation test?

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World Journal of Cardiology 2024年第1期16卷 16-26页

作者： Hiroki Teragawa Chikage Oshita Yuko uchimura Department of Cardiovascular Medicine JR Hiroshima HospitalHiroshima 732-0057Japan

BACKGROUND Although the spasm provocation test(SPT)can diagnose coronary spasms,it would be helpful if it could also predict their *** To investigate whether coronary spasms can be predicted using changes in intracoronary artery pressure measured using a pressure wire during the *** Seventy patients underwent SPTs with pressure-wire measurement of intracoronary artery *** each SPT,the pressure wire was advanced into the distal portion of the right coronary artery(RCA)and left anterior descending coronary artery,and the ratio of intracoronary pressure to aortic pressure(Pd/Pa)was *** spasm was defined as an arterial narrowing of>90%in response to the administration of acetylcholine(ACh),with chest symptoms and/or ischemic electrocardiographic *** was administered to the RCA at low,moderate,or high doses of 20,50,or 80μg,respectively,and to the left coronary artery(LCA)at low,moderate,or high doses of 50,100,or 200μg,*** arteries with coronary spasms at low doses of ACh were defined as group L,and those with coronary spasms at moderate or high doses were defined as group *** who did not occur coronary spasms at any ACh dose were designated as group *** Among the 132 coronary arteries assessed using a pressure wire,there were 49 in group N,25 in group L,and 58 in group *** Pd/Pa was the lowest in group L(P=0.001).The decrease in the Pd/Pa between baseline to low doses of ACh was lower in group MH than in group N(P<0.001).A receiver-operating characteristics analysis showed that the cutoff baseline Pd/Pa value for predicting group L was 0.95,with a sensitivity of 0.600(15/25)and a specificity of 0.713(76/107)and that the cutoff value of Pd/Pa from baseline to low doses of ACh for predicting group MH was−0.04,with a sensitivity of 0.741(43/58)and a specificity of 0.694(34/49).CONCLUSION These findings suggest that indices of intracoronary pressure during SPT may be useful means for

关键词： Acetylcholine Coronary spasm Intracoronary pressure Pressure wire Spasm provocation test Vasospastic angina

Vasospastic angina in women: Clinical backgrounds and prognoses of patients younger than and older than 60 years

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World Journal of Cardiology 2023年第4期15卷 154-164页

作者： Hiroki Teragawa Chikage Oshita Yuko uchimura Department of Cardiovascular Medicine JR Hiroshima HospitalHiroshima 732-0057Japan

BACKGROUND We frequently encounter cases of women with vasospastic angina(VSA).Additionally,some women with VSA are younger than 60 years ***,it is unknown whether the characteristics of VSA in women aged20%)detected using coronary angiography and focal spasms(coronary spasm within one segment of one coronary artery),and major cardiovascular adverse events(MACE)were assessed in both *** Smoking was more prevalent in Group Y than in Group O(P=0.04).FMD was similar in both groups(Group O:4.3%±3.2%,Group Y:4.5%±3.3%;P=0.75),whereas NID was higher in Group Y(20.5%±8.6%)than in Group O(13.6%±5.3%,P<0.01).Atherosclerosis was not detected in Group Y but was detected in Group O(61%,P<0.01).Focal spasms were less frequent in Group Y(12%)than in Group O(38%,P=0.04).The incidence of major adverse cardiac events did not differ between the two groups(P=0.40).CONCLUSIONWomen aged < 60 years with VSA have less atherosclerotic lesions and focal spasms. These characteristicsmay be affected by smoking habits and vascular smooth muscle dysfunction.

关键词： Acetylcholine Young female Smoking Vasospastic angina Vascular smooth muscle dysfunction

Bamboo as a Genetic Resource and Its Utilization from the World Wide View Point

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Journal of Agricultural Science and Technology(B) 2013年第4期3卷 239-245页

作者： Etsuzoh uchimura Botanic Gardens of Toyama Japan

The latest effective utilization of bamboo resources is changing from domestic industry to mechanical industry. This fact will be required a lot of raw material from a large scale factory, therefore, what kind of bamboo should be selected for a material. So, this study discussed on this matter through investigation and experiment. Results of this study are as follows： 1） Characteristics of bamboo different from trees and grass; 2） Environmental factors： a） annual mean temperature in 10-15 ℃ shows good growth of culm in temperate area and more than 20 ℃ also shows in tropical area, b） Rainfall： more than 1,000 mm year-1 is necessary for growth of culm in temperate and tropical area, and still more in addition to two times of 100 mm month-1 in temperate area, and three times of 200 mm month-l in tropical area, c） Soil and topography： brown colored soil and flat or gentle slope show better growth in temperate area, but red colored soil and slope are not suitable in tropical area, d） Geographical distribution of bamboo related with growth type shown in Figs. 1-3. Productivity of bamboo： annual productivity of bamboo is the biggest compared with other type of vegetation; 4） Selection of two growth type of bamboo： many big bamboos are growing in tropical area; 5） Furthermore items discussed in this report.

关键词： Genetic resources growth type zero emission biomass production.

Simple and Economical Mountain Disasters Monitoring System:A case study in Taziping,Chengdu

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Simple and Economical Mountain Disasters Monitoring System:A...

Importance of a second spasm provocation test:Four cases with an initial negative spasm provocation test

第八届海峡两岸山地灾害与环境保育学术研讨会

作者： Taro uchimura Department of Civil Engineering University of TokyoJapan

＜正＞Many after-shock slopes covered by loose deposits,when heavy rain comes,the slope is easily slide and turn into debris ***,the slope movement and the moisture of slope are most important factors for landslide and debris *** these mountain disasters,real time monitoring the slope is vital for nearby people.A MEMS based economy monitoring system is *** sensors including a tilt sensor,a soil moisture sensor,and a geomagnetic sensor,according with power supply,data storage and data transferring unit,the whole system can reach the target:quickly-install and economy solution for mountain disaster *** this idea,a demo system was setup on a sliding slope in Taziping,northwest of Chengdu city.

关键词： Monitoring system landslide clinometers wireless low power consumption

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World Journal of Cardiology 2017年第3期9卷 289-295页

作者： Hiroki Teragawa Yuichi Fujii Yuko uchimura Tomohiro Ueda Department of Cardiovascular Medicine JR Hiroshima HospitalHigashi-kuHiroshima 732-0057Japan

The spasm provocation test(SPT) is an important test in the diagnosis of vasospastic angina(VSA). In many cases, this test is performed as the gold standard test, and VSA is considered not present if the SPT is negative. However, some patients continue to experience chest symptoms despite a negative SPT. In this study, we report four cases in which SPT was repeated to evaluate chest symptoms despite the negative results of the first SPT. Two men in their 70 s, one woman in her 60 s, and one woman in her 70 s, all with chest symptoms, underwent a second SPT at 4, 3, 2, and 3 years, respectively, after the first SPT, which was negative. Three patients had positive results in the second SPT(75%). In conclusion, even when SPT is negative, the diagnosis of VSA should be made with clinical symptoms in consideration. In some cases, a second SPT may be required to confirm the diagnosis of VSA.

关键词： Coronary spasm Acetylcholine Spasm provocation test Pressure wire

降雨诱发土坡失稳过程中弹性波波速演化规律的模型试验研究

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岩石力学与工程学报 2019年第10期38卷 2138-2150页

作者：陈宇龙内村太郎清华大学水沙科学与水利水电工程国家重点实验室北京100084 东京大学土木工程系日本东京113–8656

为减少滑坡灾害造成的人员伤亡和经济损失,滑坡早期预警系统成为了最佳选择之一。提出一种利用弹性波波速预测滑坡的新方法。为了验证其有效性,进行小尺寸固定和活动边坡模型试验以及大尺寸边坡模型试验。试验结果表明,弹性波波速随着... 详细信息

为减少滑坡灾害造成的人员伤亡和经济损失,滑坡早期预警系统成为了最佳选择之一。提出一种利用弹性波波速预测滑坡的新方法。为了验证其有效性,进行小尺寸固定和活动边坡模型试验以及大尺寸边坡模型试验。试验结果表明,弹性波波速随着含水率和变形的增大而减小,临近滑坡时呈现加速减小,提出在弹性波波速加速减小时发出滑坡预警。系统设计了弹性波波速监测系统在实际应用中的工作流程,总结了实际应用面临的困难。

关键词：边坡工程滑坡早期预警降雨弹性波波速

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粒径对土持水性能的影响

岩石力学与工程学报 2016年第7期35卷 1474-1482页

作者：陈宇龙内村太郎东京大学土木工程系

进行不同粒径土样的持水特性试验,对吸湿与脱湿过程中的土–水特征曲线与滞后现象进行分析,探讨粒径对土持水性能的影响。利用***和***的土–水特征曲线模型对试验数据进行拟合,得到模型拟合参数与土–水特征曲线参数的定量关系。结果表... 详细信息

进行不同粒径土样的持水特性试验,对吸湿与脱湿过程中的土–水特征曲线与滞后现象进行分析,探讨粒径对土持水性能的影响。利用***和***的土–水特征曲线模型对试验数据进行拟合,得到模型拟合参数与土–水特征曲线参数的定量关系。结果表明:参数a与进气值呈线性增加趋势,参数m随着残余基质吸力的增大而减小,参数n也随着减湿率的增大而减小。随着有效粒径的增大,进气值、进水值、残余基质吸力在半对数坐标上均随之呈现线性减小,减湿率呈二次函数增长。滞后效应随着有效粒径的增大而减小,同样随着粒径级配累积曲线斜率的增大而减小。

关键词：土力学持水性能土–水特征曲线滞后现象

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不同干密度下非饱和土土-水特征曲线

中南大学学报（自然科学版） 2017年第3期48卷 813-819页

作者：陈宇龙内村太郎东京大学土木工程系

对吸湿与脱湿过程中引起非饱和土土-水特征曲线进行分析,观察不同密度土样的土-水特征曲线与滞后现象。利用Fredlund and Xing的土-水特征曲线模型对试验数据进行拟合,得到模型拟合参数与土-水特征曲线参数的定量关系。研究结果表明:进... 详细信息

对吸湿与脱湿过程中引起非饱和土土-水特征曲线进行分析,观察不同密度土样的土-水特征曲线与滞后现象。利用Fredlund and Xing的土-水特征曲线模型对试验数据进行拟合,得到模型拟合参数与土-水特征曲线参数的定量关系。研究结果表明:进气值随着参数a的增大而线性增大,残余基质吸力随着参数m的增大而呈幂函数减小,减湿率随着参数n的增大而呈指数减小。干密度对土-水特征曲线有显著影响。随着干密度增大,残余基质吸力与进气值及进水值增大,减湿率减小,滞后现象的显著程度降低。瓶颈效应、不同的接触角和空气体积是造成滞后效应的主要因素。

关键词：非饱和土土-水特征曲线干密度滞后现象