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Association of carbon monoxide poisonings and carboxyhemoglobin levels with COVID-19 and clinical severity

World Journal of Methodology 2023年第4期13卷 248-258页

作者： Abuzer Coskun Burak Demirci kenan ahmet turkdogan Emergency Medicine Clinic Istanbul Bagcilar Training and Research HospitalIstanbul 34200Turkey Emergency Medicine Department IstanbulÇam and Sakura City HospitalIstanbul 34494Turkey

BACKGROUND Coronavirus disease 2019(COVID-19),which recently spread throughout the entire world,is still a significant health ***,the most common cause of risky poisoning in emergency services is carbon monoxide(CO)*** disorders seem to merit more research as they have an impact on all bodily systems via the *** To determine how arterial blood gas and carboxyhemoglobin(COHb)levels affect the clinical and prognostic results of individuals requiring emergency treatment who have both COVID-19 and CO *** Between January 2018 and December 2021,479 CO-poisoning patients participated in this single-center,retrospective *** were primarily divided into two groups for analysis:Pre-pandemic and pandemic ***,the pandemic era was divided into categories based on the presence of COVID-19 and,if present,the clinical severity of the *** hospital information system was used to extract patient demographic,clinical,arterial blood gas,COVID-19 polymerase chain reaction,and other laboratory *** The mean age of the 479 patients was 54.93±11.51 years,and 187(39%)were female.226(47%)patients were in the pandemic group and 143(30%)of them had a history of *** the mean potential of hydrogen(pH)in arterial blood gas of all patients was 7.28±0.15,it was 7.35±0.10 in the pre-pandemic group and 7.05±0.16 in the severe group during the pandemic period(P<0.001).COHb was 23.98±4.19%in the outpatients and 45.26%±3.19%in the mortality group(P<0.001).Partial arterial oxygen pressure(PaO2)was 89.63±7.62 mmHg in the pre-pandemic group,and 79.50±7.18 mmHg in the severe group during the pandemic period(P<0.001).Despite the fact that mortality occurred in 35(7%)of all cases,pandemic cases accounted for 30 of these deaths(85.7%)(P<0.001).The association between COHb,troponin,lactate,partial arterial pressure of carbon dioxide,HCO3,calcium,glucose,age,pH,PaO2,potassium,sodium,and base excess levels in the

关键词： Emergency department Coronavirus disease 2019 Carbon monoxide Mortality Carboxyhemoglobin Intoxication Poisoning

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