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Coincidence of three solid tumors in a patient with multiple myeloma

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Chinese Medical Journal 2013年第6期126卷 1186-1187页

作者： Muzaffer Keklik Serdar Sivgin kemal deniz Halit Karaca Olgun Kontas Suleyman Balkanli Celalettin Eroglu Ummuhan Abdulrezzak Gulfugan Kuzu Leylagul Kaynar Mustafa Cetin Ali Unal Bulent Eser Department of Hematology Faculty of Medicine Erciyes University Kavseri Turkey Department of Pathology Faculty of Medicine Erciyes University Kavseri Turkey Department of Medical Oncology Faculty of Medicine Erciyes University Kavseri Turkey Department of Radiation Oncology Faculty of Medicine Erciyes University Kavseri Turkey Department of Nuclear Medicine Faculty of Medicine Erciyes University Kavseri Turkey Department of Internal Medicine Faculty of Medicine Erciyes University Kavseri Turkey

Multiple primary cancers （MPC） are specific .malignant tumors type, manifesting as more than one primary tumor diagnosed in the same patient, either simultaneously or sequentially. The diagnostic criteria include： the cancer must be clearly malignant as determined by histological evaluation; each cancer must be geographically separate and distinct;

关键词： colon cancer lung cancer multiple myeloma multiple primary cancer

The prevention role of Spirulina platensis(Arthrospira platensis)on intestinal health

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Food Science and Human Wellness 2022年第5期11卷 1342-1346页

作者： Ender deniz Asmaz Nilay Seyidoglu Department of Histology and Embryology Veterinary FacultyBursa Uludag UniversityNilufer 16059Turkey Department of Physiology Veterinary FacultyTekirdag Namik Kemal UniversitySuleymanpasa 59030Turkey

Spirulina is a popular herbal food that has a preventive effect on *** the study,it aimed to evaluate the effects of different doses of Spirulina platensis(Arthrospira platensis)on the morphological properties of the duodenum of rats,and to assign the effect of Spirulina on the expression of proliferating cell nuclear antigen(PCNA)in the rat duodenum,and thereby to observe the effects on intestinal health.30 male Wistar albino rats were divided into 3 groups for 45 *** first group was received the basal diet;the second group was given 500 mg/kg Spirulina daily by oral gavage;the third group was given 1000 mg/kg Spirulina *** duodenum segments were taken at the end of the trial and processed for histological *** the total mucosa,villus height and villus/cript ratio were found higher in high dose Spirulina,the lower cript depth was detected in same group compared to control and low dose group.A significant increase was observed at high dose compared to the control and low dose group in terms of PCNA expression intensity and proliferation *** suggest that high dose of Spirulina may support the duodenal growth,and thereby intestinal health.

关键词： Histochemistry Duodenum Spirulina platensis Intestinal health

The prevention role of Spirulina platensis(Arthrospira platensis) on intestinal health

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Food Science and Human Wellness 2022年

作者： Nilay SEY?DOGLU Ender deniz ASMAZ Tekirdag Namik kemal University Veterinary Faculty Department of Physiology Bursa Uludag University Veterinary Faculty Department of Histology and Embryology

Spirulina is a popular herbal food that has a preventive effect on health. In the study, it aimed to evaluate the effects of different doses of Spirulina platensis(Arthrospira platensis) on the morphological properties of the duodenum of rats, and to assign the effect of Spirulina on the expression of proliferating cell nuclear antigen(PCNA) in the rat duodenum, and thereby to observe the effects on intestinal health. 30 male Wistar albino rats were divided into 3 groups for 45 days. The first group was received the basal diet; the second group was given 500 mg/kg Spirulina daily by oral gavage; the third group was given 1 000 mg/kg Spirulina daily. The duodenum segments were taken at the end of the trial and processed for histological assay. Although the total mucosa, villus height and villus/cript ratio were found higher in high dose Spirulina, the lower cript depth was detected in same group compared to control and low dose group. A significant increase was observed at high dose compared to the control and low dose group in terms of PCNA expression intensity and proliferation index. Findings suggest that high dose of Spirulina may support the duodenal growth, and thereby intestinal health.

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The Prevalence of Celiac Disease in Patients with Diabetes Mellitus

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International Journal of Clinical Medicine 2011年第3期2卷 201-205页

作者： deniz Gokalp Senay Arikan Mustafa Yakut Yekta Tüzün Alparslan kemal Tuzcu Mithat Bahceci Senay Arikan Irfan Soykan Endocrinology Dicle University Medical SchoolDiyarbakirTurkey Gastroenterology Ankara University Medical School AnkaraTurkey Gastroenterology Dicle University Medical SchoolDiyarbakirTurkey

AIM: To determine the prevalence of celiac disease related autoantibodies in patients with type 1 and 2 diabetes mellitus (DM), and to compare these results with the general population. METHODS: In total, 137 consecutive patients with type 1 DM, 172 with type 2 DM and 113 age-sex matched control subjects were included into the study. Antigliadin-autoantibodies (AGA) IgG and IgA, and endomysial-antibodies(EMA) IgG and IgA antibodies were determined. Patients who were positive for one or more were offered a gastroduodenoscopic examination. RESULTS: AGA IgG positivity was detected in 38.7% (53/137) patients with type 1 DM in 26.2% (45/172) patients with type 2 DM and in 16.8% (19/113) control subjects (significant differences). AGA IgA positivity was detected in 24.8% (34/137) patients with type 1 DM, in 9.3% (16/172) patients with type 2 DM and in 3.5% (4/113) control subjects (significant differences). EMA IgG positivity was detected in 10.2% (14/137) patients with type 1 DM in 0.6% (1/176) patients with type 2 DM and 0.9% (1/113) control subjects (significant differences). EMA IgA positivity was detected in 11.7% (16/137) patients with type 1 DM in 0.6% (1/172) patients with type 2 DM and in none of control subjects. EMA IgA positivity was sig- nificantly higher in patients with type 1 DM as compared with patients with type 2 DM and controls. CONCLUSION: High prevalence of celiac disease at the diagnosis of type 1 DM is observed. Serological markers are useful for identifying celiac disease patients with type 1 DM.

关键词： Celiac Disease Diabetes Mellitus AGA IgA AGA IgG EMA IgA EMA IgG

中性粒细胞与淋巴细胞比值对伴随前葡萄膜炎的Behet病的影响（英文）

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国际眼科杂志 2016年第4期16卷 607-609页

作者： Avci Atil Avci deniz Cinar Salih Levent Cetinkaya Ali Karahan Samet Erden Abdulsamet Ozyurt kemal Ulas Yilmaz Ertas Ragip Pangal Emine 开塞利培训与研究医院皮肤性病科土耳其开塞利38010 开塞利培训与研究医院内科土耳其开塞利38010 埃尔吉耶斯大学医学院皮肤性病科土耳其开塞利38039 开塞利培训与研究医院眼疾科土耳其开塞利38010

目的：调查中性粒细胞与淋巴细胞比值（NLR）对伴随前葡萄膜炎的BehCet病（BD）的影响。方法：回顾性研究。研究2004-2013年间我院接收的符合BD诊断的患者。经过筛选735例BD患者,选取135例患者纳入本研究。其中68例患有前葡萄膜炎,其余... 详细信息

目的：调查中性粒细胞与淋巴细胞比值（NLR）对伴随前葡萄膜炎的BehCet病（BD）的影响。方法：回顾性研究。研究2004-2013年间我院接收的符合BD诊断的患者。经过筛选735例BD患者,选取135例患者纳入本研究。其中68例患有前葡萄膜炎,其余患者（n=67）没有任何眼部疾患。同时记录前葡萄膜炎患者的全血计数,计算NLR。结果：前葡萄膜炎组的NLR为2.55±0.96。眼部正常组的NLR为1.67±0.50。前葡萄膜炎组的NLR远高于眼部正常组（P〈0.05）。结论：伴随前葡萄膜炎的BD患者的NLR高于眼部正常BD患者。

关键词： Behet病前葡萄膜炎中性粒细胞与淋巴细胞比值

YALIKAVAK精品酒店,博德鲁姆-穆拉,土耳其

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世界建筑 2010年第7期 88-93页

作者： Suna Birsen-Otay Sevim Aslan Ipek Yurekli deniz Aslan Arda Inceoglu kemal Ozmen Ilker Aksoy Ceren Hancioglu Esin Gumus Gunseli Dolluk 项琳斐 TRafo-mimarlar建筑事务所

这座40间客房的精品酒店位于博德鲁姆的Yalikavak,美丽的爱琴海沿岸。设计通过在不同层高上交错布置遮蔽、半遮蔽和露天开放区域,营造出呼应场所地形、主导风向和景观的连续空间。

关键词：精品酒店土耳其交错布置连续空间主导风向爱琴海遮蔽客房