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Heterogeneous length-of-stay modeling of post-acute care residents in the nursing home with competing discharge dispositions

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Frontiers of Engineering Management 2022年第4期9卷 577-591页

作者： Nazmus SAKIB Xuxue SUN Nan KONG Chris MASTERSON Hongdao MENG kelly smith Mingyang LI Department of Industrial and Management Systems Engineering University of South FloridaTampaFL 33620USA College of Media Engineering Communication University of ZhejiangHangzhou 310019China Weldon School of Biomedical Engineering Purdue UniversityWest LafayetteIN 47907USA Greystone Health Network TampaFL 33610USA School of Aging Studies University of South FloridaTampaFL 33620USA

Post-acute care(PAC)residents in nursing homes(NHs)are recently hospitalized patients with medically complex diagnoses,ranging from severe orthopedic injuries to cardiovascular diseases.A major role of NHs is to maximize restoration of PAC residents during their NH stays with desirable discharge outcomes,such as higher community discharge likelihood and lower re/hospitalization *** prediction of the PAC residents’length-of-stay(LOS)with multiple discharge dispositions(e.g.,community discharge and re/hospitalization)will allow NH management groups to stratify NH residents based on their individualized risk in realizing personalized and resident-centered NH care *** to the highly heterogeneous health conditions of PAC residents and their multiple types of correlated discharge dispositions,developing an accurate prediction model becomes *** predictive analytics methods,such as distribution-/regression-based methods and machine learning methods,either fail to incorporate varied individual characteristics comprehensively or ignore multiple discharge *** this work,a data-driven predictive analytics approach is considered to jointly predict the individualized re/hospitalization risk and community discharge likelihood over time in the presence of varied residents’characteristics.A sampling algorithm is further developed to generate accurate predictive samples for a heterogeneous population of PAC residents in an NH and facilitate facility-level performance evaluation.A real case study using large-scale NH data is provided to demonstrate the superior prediction performance of the proposed work at individual and facility levels through comprehensive comparison with a large number of existing prediction methods as *** developed analytics tools will allow NH management groups to identify the most at-risk residents by providing them with more proactive and focused care to improve resident outcomes.

关键词： nursing home predictive analytics individualized prediction competing risks health outcomes

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Livedo Reticularis in a Patient with EBV Mononucleosis

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Case Reports in Clinical Medicine 2016年第2期5卷 33-36页

作者： Gorica Svalina Sean Ochsenbein J. kelly smith Department of Academic Affairs James H. Quillen College of Medicine East Tennessee State University Johnson City USA Department of Biomedical Sciences James H. Quillen College of Medicine East Tennessee State University Johnson City USA

A 23-year-old woman with serologically confirmed EBV mononucleosis presented with fever, exudative pharyngitis, periorbital and lid edema, cervical lymphadenopathy, and splenomegaly. Two weeks after the onset of symptoms she developed a generalized symmetrical reticular eruption of unbroken hexagons characteristic of livedo reticularis that resolved over several weeks as her condition improved. To our knowledge, this is the first reported case of livedo reticularis to occur in a patient with EBV mononucleosis.

关键词： Infectious Mononucleosis EBV Livedo Reticularis Reticulate Eruption

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产品标签对药物警戒的影响

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中国药物警戒 2009年第8期6卷 511-512页

作者： kelly smith 无强生制药研究与开发部美国宾夕法尼亚州霍舍姆19044 西安杨森药品安全部译

基本卫生保健建设主要致力于疾病的预防和治疗,药物治疗在基本卫生保健建设中占有重要地位。在基本卫生保健建设中,新药研发及药品的安全,在满足不断涌现的公共卫生需求方面发挥着重要作用。随着公众健康日益成为全球的重要发展领域,安... 详细信息

基本卫生保健建设主要致力于疾病的预防和治疗,药物治疗在基本卫生保健建设中占有重要地位。在基本卫生保健建设中,新药研发及药品的安全,在满足不断涌现的公共卫生需求方面发挥着重要作用。随着公众健康日益成为全球的重要发展领域,安全、有效的新药研发与生产也越发受到国际关注。

关键词：药物警戒产品标签基本卫生保健药物治疗新药研发公共卫生公众健康需求方

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法罗群岛 “拥有万条瀑布之地”

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空中英语教室（高级版．彭蒙惠英语） 2020年第5期 8-10,39页

作者： kelly smith 陈信宏(译) 不详

这座长满青草、陡悄岩壁突出于海面上的岛屿,放眼望去完全看不到一棵树。我沿看一条步道徒步,看到远方其他岛屿的高山上白雪皑皑。海鸟嘶叫着飞越蓝色的天空。我这趟徒步的目的地是岛屿尽头的红白灯塔,从那儿望去,海面无边无际地伸展至... 详细信息

这座长满青草、陡悄岩壁突出于海面上的岛屿,放眼望去完全看不到一棵树。我沿看一条步道徒步,看到远方其他岛屿的高山上白雪皑皑。海鸟嘶叫着飞越蓝色的天空。我这趟徒步的目的地是岛屿尽头的红白灯塔,从那儿望去,海面无边无际地伸展至远方的地平线。我觉得自己彷佛来到了世界的尽头。不过,这里其实只是卡尔斯岛的尽头,是海风凛冽的法罗群岛最北端的其中一座岛屿。

关键词：徒步法罗群岛岛屿地平线一棵树目的地

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发现太阳射电

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中国国家天文 2014年第10期8卷 104-108页

作者： J.kelly smith David L.smith 郭晓博(译)

1890年，著名的美国发明家托马斯．A．爱迪生，受到三年前海因里希．赫兹发现无线电波的启发，开始着手证明活动的太阳也可以发出无线电波。但是尽管他坚信这些辐射存在，但太阳射电直到52年以后才被发现。

关键词：太阳射电无线电波爱迪生托马斯发明家

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Examining the intrinsic foot muscles'capacity to modulate plantar flexor gearing and ankle joint contributions to propulsion in vertical jumping

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Journal of Sport and Health Science 2023年第5期12卷 639-647,F0003页

作者： Ross smith Glen Lichtwark Dominic Farris Luke kelly School of Human Movement and Nutrition Sciences The University of QueenslandBrisbaneQLD 4072Australia Sport and Health Sciences College of Life and Environmental SciencesThe University of ExeterExeterEX12LUUnited Kingdom

Background:During human locomotion,a sufficiently stiff foot allows the ankle plantar flexors to generate large propulsive *** foot stiffness(e.g.,via a carbon plate)increases the ankle’s external moment arm in relation to the internal moment arm(i.e.,increasing gear ratio),reduces plantar flexor muscles’shortening velocity,and enhances muscle force *** contrast,when activation of the foot’s intrinsic muscles is impaired,there is a reduction in foot and ankle work and metatarsophalangeal joint *** speculated that the reduced capacity to actively control metatarsophalangeal joint stiffness may impair the gearing function of the foot at the ***:We used a tibial nerve block to examine the direct effects of the intrinsic foot muscles on ankle joint kinetics,in vivo medial gastrocnemius’musculotendinous dynamics,and ankle gear ratio on 14 participants during maximal vertical ***:Under the nerve block,the internal ankle plantar flexion moment decreased(p=0.004)alongside a reduction in external moment arm length(p=0.021)and ankle joint gear ratio(p=0.049)when compared to the non-blocked *** medial gastrocnemius muscle-tendon unit and fascicle velocity were not different between conditions,the Achilles tendon was shorter during propulsion in the nerve block condition(p<0.001).Conclusion:In addition to their known role of regulating the energetic function of the foot,our data indicate that the intrinsic foot muscles also act to optimize ankle joint torque production and leverage during the propulsion phase of vertical jumping.

关键词： Ankle biomechanics Ankle gearing Foot biomechanicsTagedEnd

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Pilot Study on the Effects of Partially Restored Riparian Plant Communities on Habitat Quality and Biodiversity along First-Order Tributaries of the Lower St. Johns River

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Journal of Water Resource and Protection 2010年第9期2卷 771-782页

作者： Anthony M. Rossi Daniel C. Moon Dale Casamatta kelly smith Christopher Bentzien Jason McGregor Alyson Norwich Emilie Perkerson Ralph Perkerson Joanna Savinon Keith Stokes Dean Doebberfuhl 不详

The St. Johns River is one of the premiere waterways in the southeastern United States, but it is increasingly affected by anthropogenic disturbances and influences such as excessive loading of nutrients. In the current pilot project, small native plant communities (“garden sites”) were established along sections of riparian corridors of five first-order tributaries in residential-commercial areas that drain into the lower St. Johns River in north Florida. In addition, four “non-garden” (control) tributaries were monitored for comparison. Garden sites included five species native to the area;20 plants of each species on both banks (200 total plants). These sites were used to assess the ability of partially restored riparian areas to ameliorate nutrient loading and water quality and determine their impact on local biodiversity in disturbed suburban drainage systems. Partially restored sites showed a significant reduction in both NO3- and P concentrations in both soil and water samples compared to control sites. For instance, soil NO3- levels were reduced by 14% in garden sites, while water samples were 30% lower. Moreover, both plant species richness and Shannon diversity (H’) were significantly higher at partially restored sites, 33 and 19% respectively, compared to control streams after two years. Garden sites also had significantly higher terrestrial and invertebrate diversity than non-restored tributaries. Intermittent patches of partially restored habitat along suburban riparian corridors may provide a practical cost-effective technique for improving ecosystem function, water quality and increasing biodiversity along these frequently disturbed lotic habitats. Trends detected in the current study may have general implications for riparian restoration and reduction of nutrient loading in these small tributaries and, ultimately, effect water quality of the lower St. Johns River basin.

关键词： Riparian Restoration Biodiversity Soil and Water Quality

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Functional and immunological peculiarities of peripheral nerve allografts

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Neural Regeneration Research 2022年第4期17卷 721-727页

作者： kelly C.S.Roballo Jason P.Gigley Tyler A.smith George D.Bittner Jared S.Bushman School of Pharmacy University of WyomingLaramieWYUSA Department of Molecular Biology University of WyomingLaramieWYUSA Department of Molecular Biosciences University of Texas at AustinAustinTXUSA Department of Neuroscience University of Texas at AustinAustinTXUSA

This review addresses the accumulating evidence that live(not decellularized)allogeneic peripheral nerves are functionally and immunologically peculiar in comparison with many other transplanted allogeneic *** is relevant because live peripheral nerve allografts are very effective at promoting recovery after segmental peripheral nerve injury via axonal regeneration and axon *** the immunological peculiarities of peripheral nerve allografts may also be of interest to the field of transplantation in *** topics are addressed:The first discusses peripheral nerve injury and the potential utility of peripheral nerve allografts for bridging segmental peripheral nerve defects via axon fusion and axon *** second reviews evidence that peripheral nerve allografts elicit a more gradual and less severe host immune response allowing for prolonged survival and function of allogeneic peripheral nerve cells and ***,potential mechanisms that may account for the immunological differences of peripheral nerve allografts are discussed.

关键词： allograft animal model immunology neuroimmunology peripheral nerve injury regeneration repair tissue regeneration tissue transplantation transplant

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Genetic differentiation between and within Northern Native American language groups:an argument for the expansion of the Native American CODIS database

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Forensic Sciences Research 2022年第4期7卷 662-672页

作者： Jessica A.Weise Jillian Ng Robert F.Oldt Joy Viray kelly L.McCulloh David Glenn smith Sreetharan Kanthaswamy Forensic Science Graduate Program University of CaliforniaDavisCAUSA Molecular Anthropology Laboratory Department of AnthropologyUniversity of CaliforniaDavisCAUSA School of Mathematical and Natural Sciences Arizona State UniversityGlendaleAZUSA Sacramento County District Attorney’s Crime Laboratory SacramentoCAUSA California National Primate Research Center University of CaliforniaDavisCAUSA

The National Research Council recommends that genetic differentiation among subgroups of ethnic samples be lower than 3%of the total genetic differentiation within the ethnic sample to be used for estimating reliable random match probabilities for forensic *** American samples in the United States’Combined DNA Index System(CODIS)database represent four language families:Algonquian,Na-Dene,Eskimo-Aleut,and ***,a minimum of 27 Native American language families exists in the US,not including language *** goal was to ascertain whether genetic differences are correlated with language groupings and,if so,whether additional language families would provide a more accurate representation of current genetic diversity among tribal *** 21 short tandem repeat(STR)loci included in the Globalfiler^(■)PCR Amplification Kit were used to characterize six indigenous language families,including three of the four represented in the CODIS database(***,Na-Dene,and Eskimo-Aleut),and two language isolates(Miwok and Seri)using major population genetic diversity metrics such as F statistics and Bayesian clustering analysis of genotype *** of the genetic variation(97%)was found to be within language families instead of among them(3%).In contrast,when only the three of the four language families represented in both the CODIS database and the present study were considered,4%of the genetic variation occurred among the language *** clustering resulted in a maximum posterior probability indicating three genetically distinct groups among the eight language families and isolates:(1)Eskimo,(2)Seri,and(3)all other language groups and isolates,thus confirming genetic subdivision among subgroups of the CODIS Native American *** genetic structure indicates the need for an increased number of Native American populations based on language affiliation in the CODIS database as well as more robust sample sets for those langu

关键词： Forensic sciences population genetics Native Americans North America languages short tandem repeats(STRs or microsatellites)

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美国社会问题

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作者： (美)斯坦利・艾岑(D. Stanley Eitzen) (美)玛克辛・巴卡・金(Maxine Baca Zinn) (美)凯利・艾岑・史密斯(kelly Eitzen smith)

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