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支点弯曲位X线片对运用椎弓根螺钉固定治疗脊柱侧凸中的可预测性

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中华骨科杂志 2010年第6期30卷 I0037-I0042页

作者： kenneth M.C. Cheung deepa Natarajan dino Samartzis Yat-Wa Wong Wai-Yuen Cheung keith d.k. luk 宋跃明(译) Investigation performed at the department of Orthopaedics arid Traumatology Duchess of Kent Children's Hospital Hong Kong China 四川大学华西医院骨科 610041

背景：支点弯曲位X线片在运用钩棒系统治疗青少年特发性脊柱侧凸时能准确预测术后弯曲矫正情况。本研究拟探讨支点弯曲位x线片在运用交替椎弓根螺钉固定治疗脊柱侧凸中的预测性价值。方法：我们对在同一机构内运用交替椎弓根螺钉固定方... 详细信息

背景：支点弯曲位X线片在运用钩棒系统治疗青少年特发性脊柱侧凸时能准确预测术后弯曲矫正情况。本研究拟探讨支点弯曲位x线片在运用交替椎弓根螺钉固定治疗脊柱侧凸中的预测性价值。方法：我们对在同一机构内运用交替椎弓根螺钉固定方法进行手术治疗的胸椎特发性脊柱侧凸患者进行前瞻性放射学分析。测量术前和术后1周时站立后前位脊柱x线片上侧凸的Cobb角。计算支点柔韧百分比和支点弯曲矫正指数百分比。结果：42例患者纳入本研究。实施手术时患者的平均年龄是14．6岁，平均融合节段数为9．4个。术前站立位X线片Cobb角、支点弯曲位Cobb角、支点柔韧度分别为57．9°．21．8°和62．7％。术后1周X线片，平均Cobb角为15．4°，弯曲的平均矫正度为73.4％，支点弯曲的平均矫正指数为122．1％。支点弯曲位x线片的角度与支点弯曲矫正指数呈显著正相关，表明支点弯曲化X线片能预测支点弯曲的术后矫正情况。然而，对于僵硬型的脊柱侧凸，椎弓根螺钉固定能为患者带来比支点弯曲位X线片所预测的更理想的矫正效果。结论：据我们所知，本研究是证实支点弯曲位X线片在运用交替椎弓根螺钉固定治疗脊柱侧凸中的预测性价值的首次研究。弯曲的柔韧性能反映支点弯曲矫正指数的程度，即柔韧性差的侧凸畸形能获得一个更大的矫正指数。支点弯曲位x线片具有潜在的预测价值。此外．与钩棒及其他系统相比，椎弓根螺钉固定表现出更好的矫正能力。

关键词：青少年特发性脊柱侧凸椎弓根螺钉固定支点弯曲位可预测性固定治疗 X线片 Cobb角预测价值

diabetic peripheral neuropathy and neuromodulation techniques:a systematic review of progress and prospects

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Neural Regeneration Research 2025年第8期20卷 2218-2230页

作者： Rahul Mittal keelin Mckenna Grant keith Evan Mckenna Joana R.N.Lemos Jeenu Mittal khemraj Hirani diabetes Research Institute University of Miami Miller School of MedicineMiamiFLUSA department of Otolaryngology University of Miami Miller School of MedicineMiamiFLUSA Herbert Wertheim College of Medicine Florida International UniversityMiamiFLUSA School of Medicine and Public Health University of WisconsinMadisonWIUSA

Neuromodulation for diabetic peripheral neuropathy represents a significant area of interest in the management of chronic pain associated with this *** peripheral neuropathy,a common complication of diabetes,is characterized by nerve damage due to high blood sugar levels that lead to symptoms,such as pain,tingling,and numbness,primarily in the hands and *** aim of this systematic review was to evaluate the efficacy of neuromodulatory techniques as potential therapeutic interventions for patients with diabetic peripheral neuropathy,while also examining recent developments in this *** investigation encompassed an array of neuromodulation methods,including frequency rhythmic electrical modulated systems,dorsal root ganglion stimulation,and spinal cord *** systematic review suggests that neuromodulatory techniques may be useful in the treatment of diabetic peripheral *** the advantages of these treatments will enable physicians and other healthcare providers to offer additional options for patients with symptoms refractory to standard pharmacologic *** these efforts,we may improve quality of life and increase functional capacity in patients suffering from complications related to diabetic neuropathy.

关键词： diabetes mellitus diabetic peripheral neuropathy neuromodulation neurostimulation therapy non-pharmacological treatment pain management

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Engineered polycaprolactone–magnesium hybrid biodegradable porous scaffold for bone tissue engineering

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Progress in Natural Science:Materials International 2014年第5期24卷 561-567页

作者： Hoi Man Wong Paul k.Chu Frankie k.L.Leung kenneth M.C.Cheung keith d.k.luk kelvin W.k.Yeung department of Orthopaedics and Traumatology The University of Hong Kong Shenzhen key Laboratory for Innovative Technology in Orthopaedic Trauma The University of Hong Kong Shenzhen Hospital department of Physics and Materials Science City University of Hong Kong Peking University Shenzhen Institution

In this paper, we describe the fabrication of a new biodegradable porous scaffold composed of polycaprolactone(PCL) and magnesium(Mg)micro-particles. The compressive modulus of PCL porous scaffold was increased to at least 150% by incorporating 29% Mg particles with the porosity of 74% using Micro-CT analysis. Surprisingly, the compressive modulus of this scaffold was further increased to at least 236% when the silane-coupled Mg particles were added. In terms of cell viability, the scaffold modified with Mg particles significantly convinced the attachment and growth of osteoblasts as compared with the pure PCL scaffold. In addition, the hybrid scaffold was able to attract the formation of apatite layer over its surface after 7 days of immersion in normal culture medium, whereas it was not observed on the pure PCL scaffold. This in vitro result indicated the enhanced bioactivity of the modified scaffold. Moreover, enhanced bone forming ability was also observed in the rat model after 3 months of implantation. Though bony in-growth was found in all the implanted scaffolds. High volume of new bone formation could be found in the Mg/PCL hybrid scaffolds when compared to the pure PCL scaffold. Both pure PCL and Mg/PCL hybrid scaffolds were degraded after 3 months. However, no tissue inflammation was observed. In conclusion, these promising results suggested that the incorporation of Mg micro-particles into PCL porous scaffold could significantly enhance its mechanical and biological properties. This modified porous bio-scaffold may potentially apply in the surgical management of large bone defect fixation.

关键词： Magnesium Polycaprolactone Biodegradability Biocompatibility Mechanical properties

The significance of cherts as markers of Ocean Plate Stratigraphy and paleoenvironmental conditions:New insights from the Neoproterozoic-Cambrian Blovice accretionary wedge,Bohemian Massif

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Geoscience Frontiers 2023年第1期14卷 162-180页

作者： lukášAckerman Jirízák Václav kachlík Jan Pašava karelZák Andreas Pack František Veselovsky Ladislav Strnad Institute of Geology of the Czech Academy of Sciences Rozvojová269CZ-16500 Prague 6Czech Republic Czech Geological Survey Klárov3CZ-11821 Prague 1Czech Republic Institute of Geology and Paleontology Faculty of ScienceCharles UniversityAlbertov 6Prague 12843Czech Republic Geowissenschaftliches Zentrum Universität GöttingenGoldschmidtstraβe 1D-37077 GöttingenGermany Laboratories of the Geological Institutes Faculty of ScienceCharles UniversityAlbertov 6Prague 12843Czech Republic

The Ediacaran to early Cambrian Blovice accretionary complex,Bohemian Massif,hosts abundant chert bodies that formed on an oceanic plate and were involved in subduction beneath the northern margin of *** relationships of cherts to their host,their microstructure and elemental as well as isotopic compositions revealed diverse processes of chert petrogenesis reflecting depositional environment and position on the oceanic *** deep-water cherts formed through a hydrothermal precipitation of silica-rich gels on outer trench swell of the subducted slab with none or only minor addition of terrigenous *** the contrary,the shallow-water cherts formed in lagoons on seamount slopes,and at least some of them represent a product of hydrothermal replacement of former carbonate and/or evaporite *** both chert types,the hydrothermal fluids were of low temperature and continuous pervasive hydrothermal alteration of oceanic crust,together with an elevated Si content in Neoproterozoic seawater,served as the major source of *** the other hand,minor carbon enrichment in chert is mostly linked to variable incorporation of organic matter that was deposited on the *** earth element(REE)systematics of the cherts indicate predominantly oxygenated environment for the shallow-water cherts whereas the deep-water cherts were deposited in diverse redox conditions,depending on their distance from hydrothermal *** these data,we demonstrate that the cherts once formed a part of Ocean Plate Stratigraphy(OPS)now dismembered and mixed with terrigenous siliciclastic material to form OPS mé*** our data with those from the existing literature,we show that cherts can serve as significant markers of OPS since the Archean,recording a complex interplay between seafloor-related volcanic(production of MORB-and OIB-like magmas)and sedimentary processes,hydrothermal activity at mid-ocean ridges and seamount chains as well as at outer slopes o

关键词： Chert Accretionary wedge Ediacaran Triple oxygen isotopes Strontium isotopes Ocean Plate Stratigraphy

Identification of altitude profiles in 3d geovisualizations:the role of interaction and spatial abilities

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International Journal of digital Earth 2019年第2期12卷 156-172页

作者： Petr kubíček Čeněk Šašinka Zdeněk Stachoň lukáš Herman Vojtěch Juřík Tomáš Urbánek Jiří Chmelík department of Geography Faculty of ScienceMasaryk UniversityBrnoCzech Republic HUME Lab Faculty of ArtsMasaryk UniversityBrnoCzech Republic department of Psychology Faculty of ArtsMasaryk UniversityBrnoCzech Republic department of Computer Graphics and design Faculty of InformaticsMasaryk UniversityBrnoCzech Republic

Three-dimensional geovisualizations are currently pushed both by technological development and by the demands of experts in various applied *** the presented empirical study,we compared the features of real 3d(stereoscopic)versus pseudo 3d(monoscopic)geovisualizations in static and interactive digital elevation *** tested 39 high-school students in their ability to identify the correct terrain profile from digital elevation ***’performance was recorded and further analysed with respect to their spatial abilities,which were measured by a psychological mental rotation test and think aloud *** results of the study indicated that the influence of the type of 3d visualization(monoscopic/stereoscopic)on the performance of the users is not clear,the level of navigational interactivity has significant influence on the usability of a particular 3d visualization,and finally no influences of the spatial abilities on the performance of the user within the 3d environment were identified.

关键词： 3d geovisualizations stereoscopic and monoscopic 3d vision spatial abilities level of navigational interactivity

Attribution of Fano resonant features to plasmonic particle size, lattice constant, and dielectric wavenumber in square nanoparticle lattices

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Photonics Research 2014年第1期2卷 15-23页

作者： drew deJarnette Justin Norman d.keith Roper Microelectronics and Photonics Graduate Program University of ArkansasFayettevilleArkansas 72701USA department of Chemical Engineering University of ArkansasFayettevilleArkansas 72701USA

Fano resonances between plasmons and diffracted light offer tunable energies and locales,but attribution of Fano resonance features to geometry and physicochemistry of metal nanostructures and adjacent dielectrics has been confounded by complexity and computational *** work shows predictable modal shifts of Fano resonance in square lattices of plasmonic nanostructures can be attributed directly to changes in medium wavenumber,particle size,and lattice constant that alter plasmon polarizability and diffractive *** 45 to 80 nm radius particles,a window of lattice constants that support Fano resonances is identified in a range from 500 to 900 *** constants that support high intensity resonances are determined by individual particle polarizability and medium *** resonance wavelengths redshift from diffracted photon energies as local refractive index(RI)changes due to coupling with particle polarizability in the *** sensitivities for quadrupole,dipole,and Fano resonances are 150,348,and 541 nm,respectively,per RI *** resonance intensity may be enhanced more than tenfold by selecting nanoparticle sizes and lattice *** quantitative effects of such parametric changes are rapidly and intuitively distinguished using a semi-analytic approach,consisting of an exact expression for particle polarizability,a trigonometric description of diffraction,and a semianalytical coupled dipole approximation.

关键词： lattice particle wave

ANALYZING MARkET COMPETITION BETWEEN AIRBUS ANd BOEING USING A dUO HIERARCHICAL GRAPH MOdEL FOR CONFLICT RESOLUTION

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Journal of Systems Science and Systems Engineering 2017年第6期26卷 683-710页

作者： Shawei He keith W. Hipel d. Marc kilgour 1.College of Economics & Management Nanjing University of Aeronautics and Astronautics Nanjing 211106 China 2.Department of Systems Design Engineering University of Waterloo Waterloo Ontario Canada N2L 3G1 3.Centre for International Governance Innovation Waterloo Ontario Canada N2L 6C2 4.Balsillie School of International Affairs Waterloo Ontario Canada N2L 6C2 5.Department of Mathematics Wilfrid Laurier University Waterloo Ontario Canada N2L 3C5

A duo hierarchical graph model for conflict resolution is developed to investigate market competition between Airbus and Boeing over aircraft sales in the Asia Pacific region. The duo hierarchical graph model, a significant extension of the graph model for conflict resolution methodology, contains two common decision makers, who take part in two related subconflicts, as well as local decision makers, who participate in only one subconflict. New stability definitions are proposed to describe forms of sanction unique to the hierarchical model. The interrelationships between stabilities in the overall graph model and in the two local models are investigated. Then the duo hierarchical graph model is applied to the competition between Airbus and Boeing in both the wide and narrow body markets in the Asia-Pacific region. The two types of Asian airlines have different operating strategies, so that the two markets constitute sub-competitions that can be modelled naturally using the duo hierarchical graph model. The stability results indicate a resolution for all decision makers that implies marketing strategies for the aircraft manufacturers and guidelines for aircraft purchase by the airlines. Thus, this model provides decision makers with a comprehensive understanding of the dynamics of the comoetition and guidance in identifving beneficial actions.

关键词： Hierarchical Graph Model Airbus and Boeing stability results strategic resolutions

A fully-customized dataflow engine for 3d earthquake simulation with a complex topography

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Science China(Information Sciences) 2022年第5期65卷 65-80页

作者： Bingwei CHEN Haohuan FU Wayne luk Guangwen YANG department of Computer Science and Technology Beijing National Research Center for Information Science and Technology Tsinghua University National Supercomputer Center in Wuxi Ministry of Education key Laboratory for Earth System Modeling Department of Earth System ScienceTsinghua University department of Computing Imperial College London

With HPC(high performance computing) evolving into the exascale era, improvements in computing performance and power efficiency have become increasingly more important. Based on our previous work on enabling earthquake simulations on a large scale on Sunway Taihu Light, we further explore other possibilities to improve the application through a fully-customized hardware design on reconfigurable FPGA(field programmable gate array) devices. We investigate the feasibility and the potential benefits of a complete fixed-point design. We first perform a coarse-resolution-based simulation to analyze the representation range and precision needed to capture both the total energy and the energy distribution of variables over space and time. We then derive a complete fixed-point design that identifies the suitable bitwidth for major categories of variables and dynamically represents the range through a dynamic scaling scheme. Finally, we use the optimized fixed-point design to run a case of the Wenchuan earthquake to demonstrate the potential of supporting large-scale scientific simulations on FPGA devices. The results demonstrate that an 18-bit fixed-point design already provides an almost identical description of the seismic events in the Wenchuan scenario down to a single-precision floating-point version and provides sustainable performance equivalent to 13.1 Intel Xeon Gold 6154 18-core CPUs or 2.10 Sunway 260-core processors, with performance per watt(power efficiency) improved by 15.3 and 3.72 times compared with the Intel Xeon Gold 6154 18-core CPUs and the Sunway 260-core processors, respectively.

关键词： reconfigurable computing earthquake simulation FPGA hardware-software co-design architecture exploration

A Room-Temperature Chloride-Conducting Metal-Organic Crystal[Al(dMSO)_(6)]Cl_(3) for Potential Solid-State Chloride-Shuttle Batteries

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Energy & Environmental Materials 2024年第1期7卷 107-113页

作者： Bing Wu Jan Luxa Jiří Šturala Shuangying Wei lukáš d.k.novský Abhilash karuthedath Parameswaran Min Li Zdenek Sofer department of Inorganic Chemistry University of Chemistry and Technology PragueTechnická 516628Prague Czech Republic

The growing demand for substitutes of lithium chemistries in battery leads to a surge in budding novel anion-based electrochemical energy storage,where the chloride ion batteries(CIBs)take over the *** application of CIBs is limited by the dissolution and side reaction of chloride-based electrode materials in a liquid *** the flipside,its solid-state electrolytes are scarcely reported due to the challenge in realizing fast Cl^(-)*** present study reports[Al(dMSO)_(6)]Cl_(3),a solid-state metal-organic material,allows chloride ion *** strong Al-Cl bonds in AlCl_(3)are broken down after coordinating of Al^(3+)by ligand dMSO,and Cl^(-)in the resulting compound is weakly bound to complexions[Al(dMSO)_(6)]^(3+),which may facilitate Cl^(-)*** partial replacement of Cl^(-)with PF_(6)^(-),the room-temperature ionic conductivity of as-prepared electrolyte is increased by one order of magnitude from 2.172×10^(-5)S cm^(-1)to 2.012×10^(-4)S cm^(-1).When they are assembled with Ag(anode)/Ag-AgCl(cathode)electrode system,reversible electrochemical redox reactions occur on both sides,demonstrating its potential for solid-state chloride ion *** strategy by weakening the bonding interaction using organic ligands between Cl^(-)and central metallic ions may provide new ideas for developing solid chloride-ion conductors.

关键词： [Al(dMSO)_(6)]Cl_(3) chloride-ion batteries ionic conductivity metal-organic solid-state electrolytes

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