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Evaluation of the malignant potential of gliomas using diffusion-weighted and gadolinium-enhanced magnetic resonance imaging

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Brain Science Advances 2021年第4期7卷 248-256页

作者： Yoshinori Takaya Hui Chen Hirotomo TEN Katsumi Hoya Chuan-lu Jiang Ken-ichi Oyama keisuke onoda Akira Matsuno Graduate School of Medicine International University of Health and WelfareChibaJapan Department of Neurosurgery The Second Affiliated HospitalHarbin Medical UniversityHarbinChina Department of Judo Physical Therapy Faculty of Health CareTeikyo Heisei UniversityTokyoJapan Department of Neurosurgery Teikyo University Chiba Medical CenterChibaJapan

Objective:This study aimed to determine whether the apparent diffusion coefficients(ADCs)determined by diffusion-weighted imaging(DWI)of magnetic resonance imaging(MRI)could facilitate the malignancy grading of various ***:Sixty patients with a primary cerebral glioma underwent diffusion-weighted and gadolinium-enhanced(Gd)T1-weighted MRI using a 1.5-T MRI *** was performed based on signal intensities on DWI and Gd *** mean and minimum ADC values were calculated,and Ki-67 staining was performed for each histological sample to evaluate their tumor proliferative ***,the DWI,Gd,and combined scores were analyzed and compared with the Ki-67 staining index and malignant *** relationships among the mean and minimum ADC values,Ki-67staining index,and malignant grade were also ***:The minimum ADC was inversely correlated with the Ki-67staining index,with a low minimum ADC suggestive of tumor *** qualitative evaluation of the D score of water molecule diffusion on DWI accurately reflected the pathological grades of gliomas,with an effectiveness that was at least as good as the quantitative analysis using the minimum *** diagnostic value of Gd images in determining glioma malignancy grades was inferior to that of ***:Both DWI and gadolinium-enhanced images of MRI should be considered essential for the diagnosis of tumor malignancy.

关键词： apparent diffusion coefficient value diffusionweighted imaging glioma malignancy

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Temperature Dependence and P/Zn Ratio in Phosphoric Acid Treatment of Zinc Oxide

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Journal of Materials Science & Technology 2016年第5期32卷 432-436页

作者： Hiroaki onoda Yurie Sato Department of Informatics and Environmental Sciences Kyoto Prefectural University1-5Shimogamo Nakaragi-cyoSakyo-kuKyoto 606-8522Japan

Zinc oxide, which has photocatalytic activity, is used as white pigment for cosmetics. A certain degree of sebum on the skin is decomposed by ultraviolet radiation in sunlight. In this work, zinc oxide was shaken with phosphoric acid to synthesize a white pigment for cosmetics. Zinc oxide was set with 0.1 mol/L of phosphoric acid at P/Zn = 1/1 and 1/2, and then shaking in hot water for 1 h. The chemical composition, powder properties, photocatalytic activity, color phase, and smoothness of the obtained powder were studied. The P/Zn ratio in preparation had an effect on the reaction between phosphoric acid and zinc oxide. The photocatalytic activity of zinc oxide was inhibited by phosphoric acid treatment. The obtained samples had enough high reflectance at the visible light region.

关键词： Zinc oxide Photocatalytic activity Powder processing

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pH-controlled hydrothermal synthesis of titanium phosphates and their powder properties

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Journal of Advanced Ceramics 2014年第4期3卷 326-331页

作者： Hiroaki onoda Taisuke YAMAGUCHI Department of Informatics and Environmental Sciences Kyoto Prefectural University1-5Shimogamo Nakaragi-cyoSakyo-kuKyoto 606-8522Japan

Titanium phosphates were prepared from titanium chloride and sodium pyrophosphate at various pH in hydrothermal process as a novel white pigment for *** chemical composition,powder properties,photo catalytic activity,colour phase and smoothness were *** obtained materials had a higher Ti/P ratio than that used in preparation conditions because of the formation of titanium oxide and *** samples prepared at pH=4 had particles smaller than 100μ*** phosphates had less photo catalytic activity to protect the sebum on the *** obtained materials in hydrothermal process and their thermal products at 100℃showed high reflectance in the range of visible light.

关键词： titanium phosphates pyrophosphate pH photo catalytic activity smoothness

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Synthesis and catalytic properties of iron-cerium phosphate prepared in ethylene glycol using additives

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Journal of Advanced Ceramics 2013年第1期2卷 49-54页

作者： Hiroaki onoda Takeshi SAKUMURA Department of Informatics and Environmental Sciences Kyoto Prefectural University1-5Shimogamo Nakaragi-choSakyo-kuKyoto 606-8522Japan

The effects of cerium substitution,use of additives,and heating temperature on the chemical composition and catalytic activity of iron phosphate were ***-cerium phosphate was prepared from iron nitrate,ammonium cerium nitrate,and sodium phosphate in ethylene glycol using sodium dodecyl-sulfate or acetylacetone as *** chemical composition,particle shape and size distribution of the obtained samples were respectively evaluated based on ICP and XRD,SEM,and laser diffraction/scattering *** catalytic activity was evaluated based on the decomposition of the complex formed from formaldehyde,ammonium acetate,and *** peaks corresponding to FePO_(4) were observed for the samples heated at 600℃whereas samples treated at lower temperatures were ***-cerium phosphates heated at 200℃and 400℃exhibited high catalytic activity for the decomposition of the aforementioned complex.

关键词： iron phosphate cerium substitution ethylene glycol ICP analysis catalytic property

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Influences of additives on phosphoric acid treatment of titanium dioxide as a novel white pigment

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Journal of Advanced Ceramics 2015年第3期4卷 211-216页

作者： Aki MATSUKURA Hiroaki onoda Department of Informatics and Environmental Sciences Kyoto Prefectual University1-5Shimogamo Nakaragi-cyoSakyo-kuKyoto 606-8522Japan

Titanium dioxide is a photocatalytically active substance used as a white pigment for *** sunlight,titanium dioxide catalyzes decomposition of a certain amount of sebum on the skin by ultraviolet ***,a novel white pigment for use in cosmetics was developed from titanium dioxide and phosphoric acid at pH=4 with and without glycerin,sodium lactate,lactic acid,and *** chemical composition,powder properties,photocatalytic activity,color phase,and smoothness of the samples were *** of glycerin led to a decline in the intensity of the X-ray diffraction(XRD)peak of TiO_(2) relative to that of the other *** particle size of the materials prepared with and without additives was 0.3μm;however,extensive aggregation was observed in the obtained *** photocatalytic activity of TiO_(2) was inhibited by phosphoric acid *** materials prepared with sodium lactate,lactic acid,and glycerin exhibited higher photocatalytic activity than that prepared without *** obtained materials showed a high reflectance in the range of visible light,and the L^(*)values in L^(*)a^(*)b^(*) color space were high(where L^(*)defines lightness,a^(*) denotes the red/green value,and b^(*) the yellow/blue value).These results indicate that the samples prepared in this work are suitable for use as white pigments.

关键词： phosphoric acid titanium dioxide photocatalytic activity particle size

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Synthesis of bulk lanthanum polyphosphate and other rare earth phosphates through hydrothermal hot-pressing

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Journal of Advanced Ceramics 2013年第4期2卷 301-307页

作者： Hiroaki onoda Taro YAMASAKI Department of Informatics and Environmental Sciences Faculty of Life and Environmental SciencesKyoto Prefectural University1-5Shimogamo Nakaragi-choSakyo-kuKyoto 606-8522Japan

Bulk samples of lanthanum polyphosphate were synthesized through a hydrothermal hot-pressing(HHP)*** this process,pressing temperature,pressure and volume of water were varied in order to improve the density and strength of the resulting *** strength of the bulk samples was estimated through drilling and ultrasonic *** order to improve the strength of the materials,the use of microwave irradiation was *** polyphosphate formed porous bulk samples with a filling factor of approximately 70%,which was calculated from real and theoretical *** respect to machinable strength,a drilled hole greater than 7.0 mm in diameter was obtained on some bulk samples,and the diameter of the samples was 14 *** HHP process is a useful method for obtaining bulk samples of lanthanum *** lanthanum polyphosphate containing water crumbled easily to a powder form upon ***,these bulk samples retained their shape upon ultrasonication,despite containing water,after exposure to microwave irradiation,and also experienced minimal weight ***,to study the effect of microwave heating,bulk lanthanum orthophosphate,yttrium orthophosphate and polyphosphate were also examined.

关键词： lanthanum polyphosphate hydrothermal hot-pressing(HHP)process machinable strength vibration strength microwave heating

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Effect of mechanical treatment on the powder properties of zinc phosphate white pigments

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Journal of Advanced Ceramics 2015年第4期4卷 312-317页

作者： Hiroaki onoda Miho HARUKI Department of Informatics and Environmental Sciences Kyoto Prefectural University1-5Shimogamo Nakaragi-cyoSakyo-kuKyoto 606-8522Japan

Zinc oxide,which has photocatalytic activity,is used as a white pigment for cosmetics,resulting in a certain amount of sebum on the skin to be decomposed by the ultraviolet radiation in the *** this work,zinc phosphates as novel white pigments for use in cosmetics were prepared from zinc nitrate and sodium dihydrogen phosphate,and then ball-milled under various *** chemical composition,powder properties,photocatalytic activity,color phase,moisture retention,and smoothness of the zinc phosphates were *** zinc phosphate particle size was decreased by mechanical *** particular,the sample treated with sodium lactate solution had much smaller *** milled zinc phosphates exhibited less photocatalytic activity than zinc oxide,and thus should not decompose sebum on the *** milled zinc phosphates showed sufficiently high reflectance within the range of visible light to act as novel white *** sample treated with sodium lactate solution had higher water retention than the sample treated with ***,the slip resistance and roughness of the powder particles decreased as a result of treatment with sodium lactate solution.

关键词： white pigment zinc phosphate mechanical treatment photocatalytic activity water retention

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Preparation of Lanthanum Nickel Oxide-Coated Ni Sheet Anodes and Their Application to Electrolytic Production of (CF_3)_3N in (CH_3)_4NF·4.0HF Melt

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Journal of Rare Earths 2006年第1期24卷 1-8页

作者： Yoshio Shodai Minoru Inaba Kazuki onoda Akimasa Tasaka Department of Molecular Science and Technology Faculty of Engineering Doshisha University Kyotanabe Kyoto 610-0321 Japan

A new process for electrolytic production of a perfluorinated compound, （CF3）3N, using lanthanum nickel oxide-coated Ni sheet anode in the （CH3）4NF· 4.0HF melt at room temperature, was developed. Thin films of the lanthanum nickel oxides were prepared on Ni sheets by sol-gel coating method using polyvinlylpyrrolidone（PVP）. The main components of the thin films were La2O3, LaNiO3, and La2NiO4 at 500, 750 and 1000℃, respectively. The anode performance in the （CH3）4NF·4.0HF melt depends greatly on the main component of the thin film, and the LaNiO3-coated Ni sheet anode gives the best anode performance. The potential of LaNiO3-coated Ni sheet anode remains constant at 5.9 V during electrolysis at 20 mA·cm^-2 in the （CH3）4NF·4.0HF melt for 100 h. This is because LaNiO3 and NiF3 and/or Ni2F5, the latter of which was formed during electrolysis, in the film give a high electronic conductivity to the surface film during electrolysis. The maximum mole fraction of （CF3）3N （21.4%） was obtained at 20 mA·cm^-2 in （CH3）4NF·4.0HF melt using the LaNiO3-coated Ni sheet.

关键词： electrolytic perfluorination lanthanum nickel oxide perfluorotrimethylamine rare earths

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Preparation of titanium phosphate white pigments with titanium sulfate and their powder properties

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Journal of Advanced Ceramics 2014年第2期3卷 132-136页

作者： Hiroaki onoda Syohei FUJIKADO Takeshi TOYAMA Department of Informatics and Environmental Sciences Kyoto Prefectural University1-5Shimogamo Nakaragi-cyoSakyo-kuKyoto 606-8522Japan Department of Materials and Applied Chemistry College of Science and TechnologyNihon University1-8-14 Kanda-SurugadaiChiyoda-kuTokyo 101-8308Japan

Titanium oxide that has photocatalytic activity is used as white pigment for cosmetics.A certain degree of sebum on the skin is decomposed by the ultraviolet radiation in *** this work,as novel white pigment,titanium phosphates were synthesized with titanium sulfate and phosphoric acid for *** chemical composition,powder properties,photocatalytic activity,color phase,moisture retention,and smoothness were *** titanium phosphates had less photocatalytic activity to protect the sebum on the *** without heating and those heated at 100℃showed high reflectance in the range of visible *** prepared in Ti/P=3/2 had higher moisture retention than samples prepared in other Ti/P ratios.

关键词： white pigment titanium phosphates photocatalytic activity smoothness

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Useful detection of CD147 (EMMPRIN) for pathological diagnosis of early hepatocellular carcinoma in needle biopsy samples

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World Journal of Gastroenterology 2007年第21期13卷 2913-2917页

作者： Satoshi Mamori keisuke Nagatsuma Tomokazu Matsuura Kiyoshi Ohkawa Hiroshi Hano Masaharu Fukunaga Masato Matsushima Yoshifumi Masui Nao Fushiya Hiroshi onoda Yasuyuki Searashi Ichiro Takagi Hisao Tajiri Division of Gastroenterology and Hepatology Department of Internal MedicineThe Jikei University School of MedicineTokyo 105-8461Japan Department of Laboratory Medicine The Jikei University School of MedicineTokyo 105-8461Japan Department of Biochemistry 1 The Jikei University School of MedicineTokyo 105-8461Japan Department of Pathology The Jikei University School of MedicineTokyo 105-8461Japan Department of Pathology The Jikei University School of MedicineThe Daisan HospitalTokyo 105-8461Japan Division of Clinical Research and development The Jikei University School of MedicineTokyo 105-8461Japan

AIM:To make clear whether CD147 (EMMPRIN) expression in pathological tumor samples with a fine-needle aspiration biopsy is useful for pathological diagnosis of early hepatocellular carcinoma (HCC). METHODS:Twenty-two patients (15 men and 7 women; median age 68 years,range 56-81 years) underwent a liver tissue biopsy in order to make a diagnosis of HCC. Paraffin-embedded liver biopsy tissue samples from 22 patients were stained with anti-CD147 antibody,murine monoclonal antibody 12C3 (MAb12C3) for immunohistochemical analysis. An immunohistochemical analysis of CD147 was performed and the degree of staining compared between tumor and non-tumor tissue. In addition,the degree of staining within tumor tissue was compared according to a number of clinicopathological variables. RESULTS:The degree of staining of CD147 was significantly higher in tumor tissues than non-tumor tissues,even in tumors less than 15 mm in *** expression of this protein was significantly elevated in HCC tissue specimens from patients with a low value of serum AST and γ-GTP.

关键词： CD147 serves potentially as apathological target for cancer detection of early HCC.

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