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Neonatal erythema multiforme associated with a rotavirus infection:A case report

世界临床病例杂志 2023年第24期11卷 5749-5754页

作者： Jung Jae Kim joon kee lee Department of Pediatrics Chungbuk National University HospitalCheongju 28644South Korea Department of Pediatrics Chungbuk National UniversityCheongju 28644South Korea

BACKGROUND Erythema multiforme(EM)is an extremely rare condition in neonates,and studies suggest its association with certain infections and neonatal vaccinations;however,few specific etiological agents have been ***,a common pathogenic gastrointestinal virus in the neonatal period that is preventable via vaccination,has not been identified as a possible *** report the case of a neonate who was referred for skin lesions presenting as EM,where a meticulous workup identified rotavirus as the sole causative *** SUMMARY A 14-day-old male infant was admitted to our hospital with a 1-day history of skin *** medical history or medication intake was *** for the complaint of skin lesions,the caregivers denied any abnormal *** tests,including routine laboratory evaluations,were performed to identify the cause of skin *** tests for Immunoglobulin M for Toxoplasma,Rubella,Cytomegalovirus,Herpes Simplex Virus,and Epstein-Barr virus viral-capsid antigen were all *** polymerase chain reaction(PCR)tests for respiratory viruses and bacterial pathogens were negative(including the severe acute respiratory syndrome coronavirus 2).Multiple PCR tests for gastrointestinal viruses and bacterial pathogens demonstrated evidence of rotavirus *** growth was reported in the blood and urine *** patient received intravenous fluids for hydration;meanwhile,no other medications were *** lesions improved rapidly without specific treatment,and full recovery was achieved within a *** The possibility of rotavirus,a major cause of pediatric gastrointestinal infections,being a trigger for neonatal EM should be considered.

关键词： Erythema multiforme Gastrointestinal diseases Neonate Rotavirus Skin abnormalities Case report

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Multivalent network modifier upregulates bioactivity of multispecies biofilm-resistant polyalkenoate cement

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Bioactive Materials 2022年第8期7卷 219-233页

作者： Ji-Yeong Kim Woojin Choi Utkarsh Mangal Ji-Young Seo Tae-Yun Kang Joohee lee Taeho Kim Jung-Yul Cha kee-joon lee Kwang-Mahn Kim Jin-Man Kim Dohyun Kim Jae-Sung Kwon Jinkee Hong Sung-Hwan Choi Department of Orthodontics Institute of Craniofacial DeformityYonsei University College of Dentistry50-1 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea BK21 FOUR Project Yonsei University College of Dentistry50-1 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea Department of Chemical and Biomolecular Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea Department and Research Institute of Dental Biomaterials and Bioengineering Yonsei University College of Dentistry50-1 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea Johns Hopkins University 3400 N.Charles St.Mason HallBaltimoreMD 21218USA Department of Oral Microbiology and Immunology School of Dentistry and Dental Research InstituteSeoul National UniversitySeoul 08826Republic of Korea Department of Conservative Dentistry Oral Science Research CenterYonsei University College of Dentistry50-1 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea

Polyalkenoate cement(PAC)is a promising material for regenerative hard tissue *** ionically rich glass component of PAC encourages bioactive interaction *** release of essential ***,PAC bioactivity is restricted owing to(i)structurally inherent cationic network formers and(ii)surface bacterial biofilm *** two factors cause a deficiency in ion release,further complicated by secondary infections and premature therapeutic ***,a multivalent zwitterionic network modifier(mZM)is presented for upregulation of ionic exchange and bioactivity *** introducing a non-zero charged mZM into PACs,an increase in the proportion of non-bridging oxygen *** network modification promotes ion channel formation,causing a multiple-fold increase in ion release and surface deposition of hydroxy-carbonate apatite(ca.74%).Experiments ex vivo and animal models also demonstrate the efficient remineralization ability of the ***,divalent cationic interaction results in bacterial biofilm reduction(ca.68%)while also influencing a shift in the biofilm species composition,which favors commensal ***,PAC modification with mZM offers a promising solution for upregulation of bioactivity,even aiding in customization by targeting site-specific regenerative therapy in future applications.

关键词： Multivalent network modifier Bioactive materials Glass polyalkenoate cement Ion release Remineralization Multispecies biofilm resistance

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Recent Advances in Patterning Strategies for Full‑Color Perovskite Light‑Emitting Diodes

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Nano-Micro Letters 2024年第3期16卷 99-137页

作者： Gwang Heon lee Kiwook Kim Yunho Kim Jiwoong Yang Moon kee Choi Graduate School of Semiconductor Materials and Devices Engineering Center for Future Semiconductor Technology(FUST)Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea Department of Energy Science and Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea Energy Science and Engineering Research Center Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea Department of Materials Science and Engineering Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea Center for Nanoparticle Research Institute for Basic Science(IBS)Seoul 08826Republic of Korea

Metal halide perovskites have emerged as promising light-emitting materials for next-generation displays owing to their remarkable material characteristics including broad color tunability,pure color emission with remarkably narrow bandwidths,high quantum yield,and solution *** recent advances have pushed the luminance efficiency of monochromic perovskite light-emitting diodes(PeLEDs)to their theoretical limits,their current fabrication using the spincoating process poses limitations for fabrication of full-color *** integrate PeLEDs into full-color display panels,it is crucial to pattern red–green–blue(RGB)perovskite pixels,while mitigating issues such as cross-contamination and reductions in luminous ***,we present state-of-the-art patterning technologies for the development of full-color ***,we highlight recent advances in the development of efficient ***,we discuss various patterning techniques of MPHs(i.e.,photolithography,inkjet printing,electron beam lithography and laserassisted lithography,electrohydrodynamic jet printing,thermal evaporation,and transfer printing)for fabrication of RGB pixelated *** patterning techniques can be classified into two distinct approaches:in situ crystallization patterning using perovskite precursors and patterning of colloidal perovskite *** review highlights advancements and limitations in patterning techniques for PeLEDs,paving the way for integrating PeLEDs into full-color panels.

关键词： Perovskite Light-emitting diode Full-color display High-resolution patterning Electroluminescence

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Heat-induced leaf epidermal cell damage triggers autophagy-mediated mesophyll cell expansion in Arabidopsis

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Plant Communications 2024年第3期5卷 5-8页

作者： Yunji Namgung Hong Gil lee Hongwoo lee Pil joon Seo Department of Chemistry Seoul National UniversitySeoul 08826Republic of Korea Plant Genomics and Breeding Institute Seoul National UniversitySeoul 08826Republic of Korea Research Institute of Basic Sciences Seoul National UniversitySeoul 08826Republic of Korea

Dear Editor,Plants have evolved intricate mechanisms to recognize fluctuating environments,relay signals,and ultimately recover from the cellular and tissue damage imposed by environmental *** wounding,mechanical damage is recognized via cellular compounds released from damaged cells(Vega-Munoz et al.,2020)or changes in turgor pressure and cell-wall properties(Hoermayer et al.,2020).

关键词： damage Arabidopsis wound

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Vertical plane depth-resolved surface potential and carrier separation characteristics in flexible CZTSSe solar cells with over 12% efficiency

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Carbon Energy 2024年第3期6卷 36-52页

作者： Dae-Ho Son Ha Kyung Park Dae-Hwan Kim Jin-Kyu Kang Shi-joon Sung Dae-Kue Hwang Jaebaek lee Dong-Hwan Jeon Yunae Cho William Jo Taeseon lee JunHo Kim Sang-Hoon Nam kee-Jeong Yang Division of Energy Technology DGISTDaeguRepublic of Korea Research Center for Thin Film Solar Cells DGISTDaeguRepublic of Korea Department of Physics Ewha Womans UniversitySeoulRepublic of Korea Department of Physics Incheon National UniversityIncheonRepublic of Korea Department of Mechanical Engineering Massachusetts Institute of TechnologyCambridgeMassachusettsUSA

Cu2ZnSn(S,Se)4(CZTSSe)solar cells have resource distribution and economic *** main cause of their low efficiency is carrier loss resulting from recombination of photo-generated electron and *** overcome this,it is important to understand their electron-hole behavior *** determine the carrier separation characteristics,we measured the surface potential and the local current in terms of the absorber *** elemental variation in the intragrains(IGs)and at the grain boundaries(GBs)caused a band edge shift and bandgap(Eg)*** the absorber surface and subsurface,an upward Ec and Ev band bending structure was observed at the GBs,and the carrier separation was *** the absorber center,both upward Ec and Ev and downward Ec-upward Ev band bending structures were observed at the GBs,and the carrier separation was *** improve the carrier separation and suppress carrier recombination,an upward Ec and Ev band bending structure at the GBs is desirable.

关键词： carrier separation CZTSSe flexible solar cell local current surface potential

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Callus proliferation-induced hypoxic microenvironment decreases shoot regeneration competence in Arabidopsis

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Molecular Plant 2024年第3期17卷 395-408页

作者： Dohee Koo Hong Gil lee Soon Hyung Bae Kyounghee lee Pil joon Seo Department of Chemistry Seoul National UniversitySeoul 08826Korea Plant Genomics and Breeding Institute Seoul National UniversitySeoul 08826Korea Research Institute of Basic Sciences Seoul National UniversitySeoul 08826Korea

Plants are aerobic organisms that rely on molecular oxygen for respiratory energy *** conditions,with oxygen levels ranging between 1%and 5%,usually limit aerobic respiration and affect plant growth and ***,we demonstrate that the hypoxic microenvironment induced by active cell proliferation during the two-step plant regeneration process intrinsically represses the regener-ation competence of the callus in Arabidopsis *** showed that hypoxia-repressed plant regener-ation is mediated by the RELATED TO APETALA2.12(RAP2.12)protein,a memberof the Ethylene Response Factor VIl(ERF-Vll)*** found that the hypoxia-activated RAP2.12 protein promotes salicylic acid(SA)biosynthesis and defense responses,thereby inhibiting pluripotency acquisition and de novo shoot regeneration in *** and genetic analyses revealed that RAP2.12 could bind directly to the SALICYLIC ACID INDUCTION DEFICIENT 2(SID2)gene promoter and activate SA biosynthesis,repressing plant regeneration possibly via a PLETHORA(PLT)-dependent ***,the rap2.12 mutant calli exhibits enhanced shoot regeneration,which is impaired by SA *** together,these find-ings uncover that the cell proliferation-dependent hypoxic microenvironment reduces cellular pluripotency and plant regeneration through the RAP2.12-SID2 module.

关键词： callus cell proliferation-induced hypoxia SID2 plant regeneration salicylic acid RAP2.12

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Acetylacetone-TiO_(2) Promoted Large Area Compatible Cascade Electron Transport Bilayer for Efficient Perovskite Solar Cells

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Energy & Environmental Materials 2024年第2期7卷 221-228页

作者： Hyong joon lee Jin Kyoung Park Jin Hyuck Heo Sang Hyuk Im Department of Chemical and Biological Engineering Korea University145 Anam-ro Seongbuk-guSeoul 17104Korea

In designing efficient perovskite solar cells(PSCs),the selection of suitable electron transport layers(ETLs)is critical to the final device performance as they determine the driving force for selective charge ***_(2)nanoparticles(NPs)based ETLs have been a popular choice for PSCs due to superior electron mobility,but their relatively deep-lying conduction band energy levels(ECB)result in substantial potential ***,TiO_(2)NPs establish favorable band alignment owing to shallower ECB,but their low intrinsic mobility and abundant surface trap sites impede the final *** this reason,constructing a cascaded bilayer ETL is highly desirable for efficient PSCs,as it can rearrange energy levels and exploit on advantages of an individual *** this study,we prepare SnO_(2)NPs and acetylacetone-modified TiO_(2)(Acac-TiO_(2))NPs and implement them as bilayer SnO_(2)/Acac-TiO_(2)(BST)ETL,to assemble cascaded energy band ***_(2)contributes to rapid charge carrier transport from high electron mobility while Acac-TiO_(2)minimizes band-offset and effectively suppresses interfacial ***,the optimized BST ETL generates synergistic influence and delivers power conversion efficiency(PCE)as high as 23.14%with open-circuit voltage(V_(oc))reaching 1.14 ***,the BST ETL is transferred to a large scale and the corresponding mini module demonstrates peak performance of 18.39%PCE from 25 cm^(2)aperture ***,the BST-based mini module exhibit excellent stability,maintaining 83.1%of its initial efficiency after 1000 h under simultaneous 1 Sun light-soaking and damp heat(85℃/RH 85%)environment.

关键词： acetylacetone large area perovskite solar cells TiO_(2)

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A survey on the real-world clinical utilization of a traditional acupuncture in Republic of Korea:Sa-am acupuncture

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Journal of Integrative Medicine 2024年第5期22卷 570-578页

作者： Ji-Yeun Park Ye-Seul lee Hi-joon Park Seungmin Kathy lee Ji-Won lee Song-Yi Kim College of Korean Medicine Daejeon UniversityDaejeon 34520Republic of Korea Jaseng Spine and Joint Research Institute Jaseng Medical FoundationSeoul 06110Republic of Korea Acupuncture and Meridian Science Research Center Kyung Hee UniversitySeoul 02447Republic of Korea Department of Korean Medicine Korean Medical CenterLusail 201184Qatar Virginia University of Integrative Medicine ViennaVA 22182USA Department of Anatomy and Acupoint College of Korean MedicineGachon UniversitySeongnamGyeonggi 13120Republic of Korea Department of Ophthalmology Otolaryngologyand DermatologyCollege of Korean MedicineDongguk UniversityGoyangGyeonggi 10326Republic of Korea

Objective This study investigated the clinical details and usage of Sa-am acupuncture in Korean medicine clinics and explored how practicing Korean medicine doctors(KMDs)think about Sa-am *** We conducted a questionnaire-based survey of KMDs who utilize Sa-am acupuncture in their *** study comprehensively investigated issues related to clinical application of Sa-am acupuncture,needling techniques used during treatment,training methods,and directions for its future *** We analyzed 572 *** average of 50%of the patients visiting Korean medicine clinics were receiving Sa-am *** most prevalent indication for Sa-am acupuncture use was digestive *** patients’appetite level and digestive function were most frequently used indicators for selecting acupuncture *** prescription compositions,Jung-Gyuk formulas were more frequently used than Seung-Gyuk *** the needle along the flow of the channel or against the flow of the channel was most *** acupuncture style most frequently used in combination with Sa-am acupuncture was Ashi point *** of Sa-am acupuncture included its versatility,easy application,and good *** included the lack of rigorous education and training programs,difficulty in applying the principles for beginners,and insufficient clinical research *** In clinics where Sa-am acupuncture is available,KMDs were providing Sa-am acupuncture to about half of their *** were not using all of the tonification and sedation techniques which may be due to time constraints or simply a lack of ***-am acupuncture demonstrated high utility in clinical practice and high satisfaction based on the efficacy and *** training programs and high-quality research are needed to help expand the use of Sa-am acupuncture.

关键词： Sa-am acupuncture Traditional East Asian medicine Acupuncture education Acupoint selection

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The PRR-EC complex and SWR1 chromatin remodeling complex function cooperatively to repress nighttime hypocotyl elongation by modulating PIF4 expression in Arabidopsis

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Plant Communications 2024年第9期5卷 184-199页

作者： Jin Hoon Won Jeonghyang Park Hong Gil lee Sangrae Shim Hongwoo lee Eunkyoo Oh Pil joon Seo Department of Chemistry Seoul National UniversitySeoul 08826Republic of Korea Department of Life Sciences Korea UniversitySeoul 02841Republic of Korea Plant Genomics and Breeding Institute Seoul National UniversitySeoul 08826Republic of Korea Department of Forest Resources Kangwon National UniversityChuncheon 24341Republic of Korea

The circadian clock entrained by environmental light-dark cycles enables plants to fine-tune diurnal growth and developmental ***,we show that physical interactions among evening clock components,including PSEUDO-RESPONSE REGULATOR 5(PRR5),TIMING OF CAB EXPRESSION 1(TOC1),and the Evening Complex(EC)component EARLY FLOWERING 3(ELF3),define a diurnal repressive chromatin structure specifically at the PHYTOCHROME-INTERACTING FACTOR 4(PIF4)locus in *** three clock components act interdependently as well as independently to repress nighttime hypocotyl elongation,as hypocotyl elongation rate dramatically increased specifically at nighttime in the prr5-1 toc1-21 elf3-1 mutant,concomitantly with a substantial increase in PIF4 *** repression of PIF4 by ELF3,PRR5,and TOC1 is mediated by the SWI2/SNF2-RELATED(SWR1)chromatin remodeling complex,which incorporates histone H2A.Z at thePIF4 locus,facilitating robust epigenetic suppression ofPIF4 during the ***,these findings demonstrate that the PRR-EC-SWR1 complex represses hypocotyl elongation at night through a distinctive chromatin domain covering PIF4 chromatin.

关键词： hypocotyl elongation circadian clock PRR Evening Complex histone H2A.Z SWR1 complex

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Durable hierarchical phosphorus‐doped biphase MoS_(2)electrocatalysts with enhanced H^(*)adsorption

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Carbon Energy 2024年第4期6卷 104-114页

作者： Yongteng Qian Jianmin Yu Zhiyi Lyu Qianwen Zhang Tae Hyeong lee Huan Pang Dae joon Kang College of Pharmacy Jinhua PolytechnicJinhuaZhejiangChina Department of Physics Sungkyunkwan UniversitySuwonGyeonggi‐doRepublic of Korea International Collaborative Laboratory of 2D Materials for Optoelectronic Science and Technology of Ministry of Education Institute of Microscale OptoelectronicsShenzhen UniversityShenzhenGuangdongChina School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhouJiangsuChina

Phase engineering is an efficient strategy for enhancing the kinetics of electrocatalytic ***,phase engineering was employed to prepare high‐performance phosphorous‐doped biphase(1T/2H)MoS_(2)(P‐BMS)nanoflakes for hydrogen evolution reaction(HER).The doping of MoS_(2)with P atoms modifies its electronic structure and optimizes its electrocatalytic reaction kinetics,which significantly enhances its electrical conductivity and structural stability,which are verified by various characterization tools,including X‐ray photoelectron spectroscopy,high‐resolution transmission electron microscopy,X‐ray absorption near‐edge spectroscopy,and extended X‐ray absorption fine ***,the hierarchically formed flakes of P‐BMS provide numerous catalytic surface‐active sites,which remarkably enhance its HER *** optimized P‐BMS electrocatalysts exhibit low overpotentials(60 and 72 mV at 10 mA cm^(−2))in H_(2)SO_(4)(0.5 M)and KOH(1.0 M),*** mechanism of improving the HER activity of the material was systematically studied using density functional theory calculations and various electrochemical characterization *** study has shown that phase engineering is a promising strategy for enhancing the H*adsorption of metal sulfides.

关键词： 1T/2H MoS_(2) density functional theory electrocatalysts phase engineering phosphorous doping

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