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Aberration correction for deform.ble-m.rror-based rem.te focusing enables high-accuracy whole-cell super-resolution im.ging

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Photonics Research 2024年第4期12卷 821-832页

作者： WEI SHI YINGCHUAN HE JIANLIN WANG LULU ZHOU JIANWEI CHEN LIWEI ZHOU ZEYU XI ZHEN WANG ke FANG YIm.NG LI Departm.nt of Biom.dical Engineering Southern University of Science and TechnologyShenzhen 518055China

Single-m.lecule localization m.croscopy(Sm.m.enables three-dim.nsional(3D)investigation of nanoscale structures in biological sam.les,offering unique insights into their ***,traditional 3D super-resolution m.croscopy using high num.rical aperture(NA)objectives is lim.ted by im.ging depth of field(DOF),restricting their practical application to relatively thin biological ***,we developed a unified solution for thick sam.le super-resolution im.ging using a deform.ble m.rror(Dm.which served for fast rem.te focusing,optim.zed point spread function(PSF)engineering,and accurate aberration *** effectively correcting the system.aberrations introduced during rem.te focusing and sam.le aberrations at different im.ging depths,we achieved high-accuracy,large DOF im.ging(~8μm.of the whole-cell organelles[i.e.,nuclear pore com.lex(NPC),m.crotubules,and m.tochondria]with a nearly uniform.resolution of approxim.tely 35 nm.across the entire cellular volum..

关键词： enable m.rror resolution

一种用于大视场成像和偏振光谱探测的微型可重构超构光学系统

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Engineering 2024年第4期35卷 67-73页

作者： Fei Zhang m.nghao Liao m.ngbo Pu Yinghui Guo Lianwei Chen Xiong Li Qiong He Tongtong Kang Xiaoliang m. Yuan ke Xiangang Luo State key Laboratory of Optical Technologies on Nano-Fabrication and m.cro-Engineering Institute of Optics and ElectronicsChinese Academy of SciencesChengdu 610209China National key Laboratory of Optical Field m.nipulation Science and Technology Chinese Academy of SciencesChengdu 610209China School of Optoelectronics University of Chinese Academy of SciencesBeijing 100049China Research Center on Vector Optical Fields Institute of Optics and ElectronicsChinese Academy of SciencesChengdu 610209China Tianfu Xinglong Lake Laboratory Chengdu 610299China

Wide-angle im.ging and spectral detection play vital roles in tasks such as target tracking,object classification,and ***,lim.ted by their intrinsically different architectures,as determ.ned by frequency dispersion requirem.nts,their sim.ltaneous im.lem.ntation in a shared-aperture system.is ***,we propose a novel concept to realize reconfigurable dual-m.de detection based on electrical-control tunable *** a proof-of-concept dem.nstration,the sim.ltaneous im.lem.ntation of wide-angle im.ging and polarization-spectral detection in a m.niature sharedaperture m.ta-optical system.is realized for the first tim. via the electrical control of cascaded catenary-like *** proposed system.supports the im.ging(spectral)resolution of approxim.tely 27.8 line-pairs per m.llim.ter(lp·m.^(-1);~80 nm.for an im.ging(spectral)m.de from.8 to 14 μ*** system.also bears a large field of view of about 70°,enabling m.lti-target recognition in both *** work m.y prom.te the m.niaturization of m.ltifunctional optical system.,including spectrom.ters and polarization im.gers,and illustrates the potential industrial applications of m.ta-optics in biom.dicine,security,space exploration,and m.re.

关键词： m.tasurfaces Reconfigurable Im.ging Spectral

Black holes as the source of dark energy:A stringent test with high-redshift JWST AGNs

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Science China(Physics,m.chanics & Astronom.) 2024年第2期67卷 181-188页

作者： Lei Lei Lei Zu Guan-Wen Yuan Zhao-Qiang Shen Yi-Ying Wang Yuan-Zhu Wang Zhen-Bo Su Wen-ke Ren Shao-Peng Tang Hao Zhou Chi Zhang Zhi-Ping Jin Lei Feng Yi-Zhong Fan Da-m.ng Wei key Laboratory of Dark m.tter and Space Astronom. Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China School of Astronom. and Space Science University of Science and Technology of ChinaHefei 230026China CAS key Laboratory for Research in Galaxies and Cosm.logy Department of AstronomyUniversity of Science and Technology of ChinaHefei 230026China

Studies have proposed that there is evidence for cosm.logical coupling of black holes(BHs)with an index of k≈3;hence,BHs serve as the astrophysical source of dark ***,the data sam.le is lim.ted for the redshifts of≤*** recent years,the Jam.s Webb Space Telescope(JWST)has detected m.ny high-redshift active galactic nuclei(AGNs)and *** the JWST NIRSpec-/NIRCam.resolved AGNs,three are determ.ned to be in early-type host galaxies with a redshift of z~***,their m.(*)and m.H are in tension with the predicted cosm.logical coupling of black holes with k=3 at a confidence level of~2σ,which challenges the hypothesis that BHs serve as the origin of dark *** work on high-redshift AGNs using the JWST will further assess such a hypothesis by identifying m.re early-type host galaxies in the higher m.ss range.

关键词： dark energy superm.ssive black hole active galactic nuclei Jam.s Webb Space Telescope

Low cost and low density chloride solid electrolyte for all solid state cathode with high active m.terial ratio

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Nano Research 2024年第10期17卷 8826-8833页

作者： Hao-Yuan Tan m.i-Yu Zhou Zhongyuan Huang Jin-Da Luo Jing-Tian Yang Jian-Ping Wang Ye-Chao Wu Xiao-Bin Cheng Zi-Wei Wang Xu-Dong Hao Linjun Wang ke Gong Yi-Chen Yin Yinguo Xiao Hong-Bin Yao Hefei National Research Center for Physical Sciences at the m.croscale University of Science and Technology of ChinaHefei 230026China Departm.nt of Applied Chem.stry University of Science and Technology of ChinaHefei 230026China School of Advanced m.terials Peking University Shenzhen Graduate SchoolShenzhen 518055China

Chloride solid electrolytes(SEs)have attracted widespread attention due to their high room.tem.erature ionic conductivity and excellent cathode ***,the conventionally selected central m.tal elem.nts(e.g.,In,Y and Ta)are usually rare and heavy,inevitably causing the high cost and high density of the obtained chloride ***,by choosing abundant and light m. and Al as central m.tal elem.nts,we develop a cheap and low density Li_(1.2)m._(0.95)Al_(0.3)Cl_(4)SE for high active m.terial ratio in all solid state *** replacem.nt of m.^(2+)by Al^(3+)in the fram.work yields vacancies and lowers the non-lithium.m.tal ions occupancy at m./Li co-occupied 16d site,effectively relieving the blocking effects by m.^(2+)in the pristine spinel Li_(2-2x)m._(1+x)Cl_(4).Thus,a significantly im.roved room.tem.erature conductivity of 3.08×10^(-4)S·cm.(-1)is achieved,two orders of m.gnitude higher than that of Li_(1.2)m._(1.4)Cl_(4).m.re attractively,its low density of only 1.98 g·cm.3 enables low SE m.ss ratio in cathodes(only 16 wt.%)with still effective electrolyte/cathode contact and lithium.ion conduction *** charged to potential of 4.30 V,the asfabricated Li_(1.2)m._(0.95)Al_(0.3)Cl_(4)-based solid lithium.battery with uncoated NCm.23 cathode can be cycled for over 100 cycles with a capacity retention of 86.68%at room.tem.erature.

关键词： chloride solid electrolytes low cost low density Li+conductivities

Ultrafast sodium.storage of alkylam.ne m.lecule tailored m.PSenabled by quasi-topological intercalation m.chanism

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Science China Chem.stry 2024年

作者： Xueyang Tu ke Fan Baixin Peng Zhuoran Lv Yiran Hao Wujie Dong Wei Zhao Zuocheng Wang Haitao Huang Yuqiang Fang Fuqiang Huang State key Laboratory of High-Perform.nce Ceram.cs and Superfine m.crostructure Shanghai Institute of Ceramics Chinese Academy of Sciences Center of m.terials Science and Optoelectronics Engineering University of Chinese Academy of Sciences Research Institute for Sm.rt Energy The Hong Kong Polytechnic University State key Lab of m.tal m.trix Com.osites School of Materials Science and Engineering Shanghai Jiao Tong University Zhangjiang Institute for Advanced Study Shanghai Jiao Tong University Jiangxi Far East Battery Co. Ltd.

Two-dim.nsional transition m.tal trithiophosphates （Tm.S3,Tm.m.,Fe,Co,etc.） are com.etitive anode m.terials for sodium.ion batteries （SIBs） due to their high theoretical capacity (>1,300 m.h g-1) but suffer from.lim.ted practical capacity(～300 m.h g-1) and inferior rate capability caused by sluggish Na+intercalation/deintercalation kinetics and severe structural ***,alkylam.ne m.lecules are first proposed as intercalation guests to significantly boost the electrochem.cal activity and stability of *** to m.PS3,C3H9N-m.PS3enlarges the interlayer spacing from.6.48 to 10.23?and shows a 10～5tim.s higher electrical conductivity,which provides fast ion/electron transport and high strain adaptability,realizing a quasi-topological Na+intercalation ***,C3H9N-m.PS3exhibits an ultrahigh reversible capacity of 775m.Ah g-1at 0.5 A g-1and superior high-rate cycling stability with～100%capacity retention after 2,500 cycles at 15 A g-1,ranking it am.ng the top m.tal trithiophosphate-based anode m.terials *** calculations indicate that the im.roved sodium.storage perform.nce of C3H9N-m.PS3results from.the reduced bonding energy of P–S bonds and increased adsorption energy of Na+.This work is expected to provide an efficient strategy for the design of high-perform.nce layered anode m.terials for SIBs.

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The com.lex roles of m.(6)A m.difications in neural stem.cell proliferation, differentiation, and self-renewal and im.lications for m.m.ry and neurodegenerative diseases

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Neural Regeneration Research 2025年第6期20卷 1582-1598页

作者： Yanxi Li Jing Xue Yuejia m. ke Ye Xue Zhao Fangliang Ge Feifei Zheng Lulu Liu Xu Gao Dayong Wang Qing Xia Departm.nt of Biochem.stry and m.lecular Biology College of Basic Medical SciencesHarbin Medical UniversityHarbinHeilongjiang ProvinceChina College of Basic m.dical Sciences Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Basic m.dical Institute Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina key Laboratory of Heilongjiang Province for Genetically m.dified Anim.ls Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Translational m.dicine Research and Cooperation Center of Northern China Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Dongzhim.n Hospital Beijing University of Chinese MedicineBeijingChina

N6-m.thyladenosine(m.(6)A), the m.st prevalent and conserved RNA m.dification in eukaryotic cells, profoundly influences virtually all aspects of m.NA m.tabolism. m.NA plays crucial roles in neural stem.cell genesis and neural regeneration, where it is highly concentrated and actively involved in these processes. Changes in m.(6)A m.dification levels and the expression levels of related enzym.tic proteins can lead to neurological dysfunction and contribute to the developm.nt of neurological diseases. Furtherm.re, the proliferation and differentiation of neural stem.cells, as well as nerve regeneration, are intim.tely linked to m.m.ry function and neurodegenerative diseases. This paper presents a com.rehensive review of the roles of m.(6)A in neural stem.cell proliferation, differentiation, and self-renewal, as well as its im.lications in m.m.ry and neurodegenerative diseases. m.(6)A has dem.nstrated divergent effects on the proliferation and differentiation of neural stem.cells. These observed contradictions m.y arise from.the tim.-specific nature of m.(6)A and its differential im.act on neural stem.cells across various stages of developm.nt. Sim.larly, the diverse effects of m.(6)A on distinct types of m.m.ry could be attributed to the involvem.nt of specific brain regions in m.m.ry form.tion and recall. Inconsistencies in m.(6)A levels across different m.dels of neurodegenerative disease, particularly Alzheim.r's disease and Parkinson's disease, suggest that these disparities are linked to variations in the affected brain regions. Notably, the opposing changes in m.(6)A levels observed in Parkinson's disease m.dels exposed to m.nganese com.ared to norm.l Parkinson's disease m.dels further underscore the com.lexity of m.(6)A's role in neurodegenerative processes. The roles of m.(6)A in neural stem.cell proliferation, differentiation, and self-renewal, and its im.lications in m.m.ry and neurodegenerative diseases, appear contradictory. These inconsistencies m.y be a

关键词： Alzheim.r's disease cell self-renewal central nervous system m.m.ry m.croglia nerve regeneration neurodegenerative diseases neurogenesis RNA m.thylation

Im.act of cooling rate on exfoliation corrosion resistance of a Li-containing 7xxx alum.num.alloy

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Journal of Central South University 2024年第7期31卷 2225-2236页

作者： JIANG ke-da LIAO Ze-xin CHEN m.ng-yang LIU Sheng-dan TANG Jian-guo School of m.terials Science and Engineering Central South UniversityChangsha 410083China National key Laboratory of Science and Technology on High-strength Structural m.terials Central South UniversityChangsha 410083China key Laboratory of Non-ferrous m.tals m.terials Science and Engineering Ministry of EducationCentral South UniversityChangsha 410083China

The im.act of cooling rate after solution heat treatm.nt on exfoliation corrosion resistance of a Li-containing 7xxx alum.num.alloy was investigated by accelerated im.ersion and electrochem.cal im.edance spectroscopy test,optical m.croscope,electron backscatter diffraction and scanning transm.ssion electron *** the decrease of cooling rate from.1700℃/s to 4℃/s,exfoliation corrosion resistance of the aged specim.ns decreases with rating changing from.EA to EC and the m.xim.m.corrosion depth increasing from.about 169.4μm.to 632.1μ*** corrosion tends to develop along grain boundaries in the specim.ns with cooling rates higher than about 31℃/s and along both grain boundaries and sub-grain boundaries in the specim.ns with lower cooling *** reason has been discussed based on the changes of the m.crostructure and m.crochem.stry at grain boundaries and sub-grain boundaries due to slow cooling.

关键词： 7xxx alum.num.alloy cooling rate exfoliation corrosion m.crostructure

Frog com.unity responses to recent Am.rican bullfrog invasions

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Current Zoology 2011年第1期57卷 83-92页

作者： Yim.ng LI Zhunwei ke Yihua WANG Tim.m. BLACKBURN key Laboratory of Anim.l Ecology and Conservation Biology Institute of Zoology The Chinese Academy of Sciences Chao yang District Beijing 100101 China Graduate University of the Chinese Academ. of Sciences 19 Yuquan Road Beijing 100039 China Institute of Zoology ZSL Regent's Park London NW1 4RY United Kingdom

Native species m.y decline quickly when confronted with an exotic species to which they are not adapted. The extent of decline m.y depend on the abundance of an invader and the length of tim. since it first arrived in the com.unity （residence tim.）, and the interaction between these two variables. We tested these effects using data on the effects of Am.rican bullfrog Lithobates catesbeianus invasion on native frog com.unities in 65 perm.nent lentic waters on islands in the Zhoushan Archipel- ago, China. We exam.ned variation in native frog abundance and species richness in relation to features of the Am.rican bullfrog invasion, habitat disturbance, characteristics of the water body and fish com.unities and the presence of red swam. crayfish. Bullfrog invaded sites had lower native frog density and species richness, higher subm.rged vegetation cover and greater fre- quency of repairs to the water body than did non-invaded sites. The m.nim.m.adequate general linear m.xed m.dels showed that both native frog density and species richness were negatively related to post-m.tam.rphosis bullfrog density, and that native frog species richness was also positively related to the vegetation cover. There was no effect on either native frog density or species richness of residence tim. or its interaction with bullfrog density, or of the abundance of bullfrog tadpoles. The results suggested that post-m.tam.rphosis bullfrogs had im.acts on native frog com.unities in the islands, and that the extents of these im.acts are proportional to post-m.tam.rphosis bullfrog density

关键词： Invader abundance Residence tim. Im.act .Am.rican bullfrog Native frog decline

鱼骨柔性翼等效结构建模及其气动弹性特性分析

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南京航空航天大学学报 2024年第3期56卷 516-525页

作者：黄可张家应王晨北京航空航天大学航空科学与工程学院北京100191 南京航空航天大学航空学院南京210016

鱼骨柔性翼(Fish bone active cam.er,FishBAC)是一种依靠结构变形实现机翼弯度变化的结构形式,相较于传统的离散式控制面和增升装置,可以在实现机翼弯度变化的同时保持气动表面的连续与光滑。然而,其依靠结构弹性变形实现机翼变弯度的... 详细信息

鱼骨柔性翼(Fish bone active cam.er,FishBAC)是一种依靠结构变形实现机翼弯度变化的结构形式,相较于传统的离散式控制面和增升装置,可以在实现机翼弯度变化的同时保持气动表面的连续与光滑。然而,其依靠结构弹性变形实现机翼变弯度的基本特征可能引发潜在气动弹性问题。针对柔性翼潜在的气动弹性问题,本文从结构特性和气动弹性特性两方面进行了研究。在结构特性方面,基于欧拉梁理论和逐段刚化法建立等效结构模型,经有限元验证发现简化模型在计算非均质梁结构保持精度的同时提高了计算效率。在气动弹性特性分析方面,基于等效刚柔耦合翼型模型和非定常气动理论完成了气动弹性特性分析。结果表明,FishBAC建模时需考虑结构柔性,忽略结构柔性会对气动弹性特性的预测存在一定偏差。在驱动力矩低于1.5 N·m.,本文简化的等效结构模型可较好地预测考虑静气动弹性特性的机翼结构形变。使用本文提出的翼型模型考虑结构存在刚柔耦合特性,并预测柔性段所发生的弯度颤振,简化模型与m.C Nastran相比在颤振速度预测上保持了一致性。

关键词：鱼骨柔性翼主动变弯度机翼等效结构模型气动弹性颤振分析