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An association study of the single-nucleotide polymorphism c190C〉T （Arg64Cys） in the human testis-specific histone variant, H3t, of Japanese patients with Sertoli cell-only syndrome

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Asian Journal of Andrology 2018年第5期20卷 527-528页

作者： Toshinobu Miyamoto Masashi Iijima Takeshi shin Gaku Minase Hiroto Ueda yasuaki Saijo Hiroshi Okada kazuo Sengoku Department of Obstetrics and Gynecology Asahikawa Medical University Asahikawa 078-8510 Japan Department of Urology Kanazawa University Graduate School of Medical Science Kanazawa 920-8641 Japan Department of Urology Dokkyo Medical University Koshigaya Hospital Koshigaya 343-8555 Japan Division of Public Health and Epidemiology Department of Social Medicine Asahikawa Medical University Asahikawa 078-8510 Japan

Dear Editor,Approximately 20% of men with nonobstructive azoospermia （NOA） are diagnosed with infertility caused by genetic defects.1 These include chromosomal abnormalities, Y-chromosome microdeletions, and several specific gene mutations/deletions, such as in DAZ, RBMY, USP9Y, SYCP3, HSF2, PLK4, and TEX11.1,2 Several histones have been detected in mammalian testes, and testis-specific variants are specifically and highly expressed during spermatogenesis^3.

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Threshold dynamics of reaction-diffusion partial differential equations model of Ebola virus disease

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International Journal of Biomathematics 2018年第8期11卷 235-264页

作者： kazuo yamazaki University of Rochester Department of Mathematics Rochester NY 14627 USA

We study the reaction-diffusion Ebola PDE model that consists of equations that govern the evolution of susceptible, in fee ted, recovered and deceased human individuals, as well as Ebola virus pathogens in the environment, with diffusive terms in all except the equation of the deceased human individuals. Under the setting of a spatial domain that is bounded, we prove the global well-posedness of the system;in contrast to the previous work on similar models such as cholera, avian influenza, malaria and dengue fever, diffusion coefficients may be different. Moreover, we derive its basic reproduction number, and under the condition that the diffusion coefficients of the susceptible and infected hosts are same, we prove the global stability of the disease-free-equilibrium, and uniform persistence in cases when the basic reproduction number lies beneath and above one, respectively. Again, we do not require that the diffusion coefficients of the recovered hosts be the same as the diffusion coefficients of the susceptible and infected hosts, in contrast to previous work on other models of infectious diseases. Another technical difficulty in our model is that the solution semiflow is not compact due to the lack of diffusion in the equation of the deceased human individuals;we overcome this difficulty using functional analysis techniques concerning Kura to wski measure of non-compactness.

关键词： Basic reproduction number Ebola persistence stability

Effects of Cultivation Conditions on Chlorophyll Biosynthesis and Carotenoid Accumulation of the Microalga Chlorella Fusca

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Journal of Chemistry and Chemical Engineering 2013年第5期7卷 431-440页

作者： kazuo Kondo shin Okamoto Michiaki Matsumoto Department of Chemical Engineering and Materials Science Doshisha University Kyoto 610-0321 Japan

The purpose of the present study is to optimize the cultivation conditions for the productivities of chlorophyll and carotenoid of the microalga chlorellafusca in a flow bioreactor. The effects of CO2 concentration in aeration and light intensity as the culture condition were firstly examined. After the cultivation conditions as to CO2 concentration and light intensity were determined, the effects of the concentrations of KNO3, CH3COONa, NaC1 and MgSO4 in the culture medium on the chlorophyll biosynthesis and carotenoid accumulation ofC. fusca were examined. KNO3 and CH3COONa were used as the nitrogen and the organic carbon sources, respectively. They are very important nutrient sources to the microalgae. In fact, when the concentration of the nutrient sources was increased, the syntheses of chlorophyll and the carotenoid accumulation of the microalgae were promoted. Cfusca can take an organic carbon as the nutrient sources for its own growth, so the cell is activated compared to the case only in an inorganic nourishment sources. Mg2＋ is known as a raw material of chlorophyll and it can promote carotenoid accumulation. However, when it exists in excessive quantity, the microalgae receive a stress and it was difficult for microalgae to uptake such nutrient sources. In this study, it was found that there existed the optimum amounts of KNO3, CH3COONa, NaCI and MgSO4 which should be added to the culture medium.

关键词： Chlorophyll carotenoid microalgae chlorella fusca tubular bioreactor photoautotrophic cultivation.

A Switching Controller System for a Wheeled Mobile Robot

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Journal of Bionic Engineering 2007年第4期4卷 281-289页

作者： Masanori Sato Atushi Kanda kazuo Ishii Department of Brain Science and Engineering Kyushu Institute of Technology Kitakyushu 808-0196 Japan

A wheeled mobile mechanism with a passive and/or active linkage mechanism for rough terrain environment is developed and evaluated. The wheeled mobile mechanism which has high mobility in rough terrain needs sophisticated system to adapt various environments. We focus on the development of a switching controller system for wheeled mobile robots in rough terrain. This system consists of two sub-systems： an environment recognition system using link angles and an adaptive control system. In the environment recognition system, we introduce a Self-Organizing Map （SOM） for clustering link angles. In the adaptive controllers, we introduce neural networks to calculate the inverse model of the wheeled mobile robot. The environment recognition system can recognize the environment in which the robot travels, and the adjustable controllers are tuned by experimental results for each environment. The dual sub-system switching controller system is experimentally evaluated. The system recognizes its environment and adapts by switching the adjustable controllers. This system demonstrates superior performance to a well-tuned single PID controller.

关键词： mobile robot rough terrain neural network Self-Organizing Map

Concept of Intelligent Mechanical Design for Autonomous Mobile Robots

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Journal of Bionic Engineering 2007年第4期4卷 217-226页

作者： Amir A. F Nassiraei kazuo Ishii Kyushu Institute of Technology Kitakyushu Fukuoka 808-0196 Japan

The concept of Intelligent Mechanical Design （IMD） is presented to show how a mechanical structure can be designed to affect robot controllability, simplification and task performance. Exploring this concept produces landmarks in the territory of mechanical robot design in the form of seven design principles. The design principles, which we call the Mecha-Telligence Principles （MTP）, provide guidance on how to design mechanics for autonomous mobile robots. These principles guide us to ask the right questions when investigating issues concerning self-controllable, reliable, feasible, and compatible mechanics for autonomous mobile robots. To show how MTP can be applied in the design process we propose a novel methodology, named as Mecha-Telligence Methodology （MTM）. Mechanical design by the proposed methodology is based on preference classification of the robot specification described by interaction of the robot with its environment and the physical parameters of the robot mechatronics. After defining new terms, we investigate the feasibility of the proposed methodology to the mechanical design of an autonomous mobile sewer inspection robot. In this industrial project we show how a passive-active intelligent moving mechanism can be designed using the MTM and employed in the field.

关键词： mechanical design intelligent autonomous robot mobile robot

Creep-fatigue interaction properties of nickel-based superalloy 617

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Acta Metallurgica Sinica(English Letters) 2011年第2期24卷 125-131页

作者： kazuo KOBAyaSHI Masao HAyaKAWA Megumi KIMURA National Institute for Materials Science (NIMS) Materials Reliability Center

High-temperature fatigue properties were investigated for a nickel-based superalloy 617 as a typical candidate material for high-temperature components using an advanced ultra super critical （A-USC） power plant. Creep-fatigue data obtained by strain-controlled tests at 700 ？ C was analyzed for the superalloy 617 focused on position of hold at peak strain in comparison with continuously cycled tests. The fatigue life was the shortest with the hold tensile strain wave, which showed mainly intergranular fracture appearance. The life was the longest with symmetrical triangular wave which fractured from the specimen surface, while the wave with the hold compressive strain showed partially intergranular fracture appearance and the life was middle in the both waves. In this study, it is discussed with the creep-fatigue interaction for the superalloy 617.

关键词： A-USC power plant Nickel-based superalloy Creep-fatigue interaction Fractography

A QUANTITATIVE MODEL FOR INTRADAY STOCK PRICE CHANGES BASED ON ORDER FLOWS

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Journal of Systems Science & Complexity 2014年第1期27卷 208-224页

作者： LIMeng HUI Xiaofeng ENDO Misao KISHIMOTO kazuo School of Management Harbin Institute of Technology Harbin 150001 China. Socio-economic Research Center Central Research Institute of Electric Power Industry Tokyo 100-8126 Japan. Graduate School of Systems Information Engineering University of Tsukuba Ibaraki-ken 305-8571 Japan.

This paper proposes a double Markov model of the double continuous auction for describing intra-day price changes. The model splits intra-day price changes as the repetition of one tick price moves and assumes order arrivals are independent Poisson random processes. The dynamic process of price formation is described by a birth-death process of the double M/M/1 server queue corresponding to the best bid/ask. The initial depths of the best bid and ask are defined as different constants depending on the last price change. Thus, the price changes in the model follow a first-order Markov process. As the initial depth of the best bid/ask is originally larger than that of the opposite side when the last price is down/up, the model may explain the negative autocorrelations of the price of the best bid/ask. The estimated parameters are based on the real tick-by-tick data of the Nikkei 225 futures listed in Osaka Stock Exchanges. The authors find the model accurately predicts the returns of Osaka Stock Exchange average.

关键词： Intra-day price changes market microstructure order flow queuing theory.

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工资和物价:过去、现在和未来

金融市场研究 2024年第3期 80-89页

作者：植田和男徐恒革(编译) 日本央行不详

一、引言2022年,日本央行前行长黑田东彦在日本经济团体联合会(Keidanren)会议上指出,日本“正在接近打破长期低通胀和低增长的关键时刻”。回首望去,2023年的确是朝着转型迈进的一年。日本经济已转向温和复苏,主要体现在经济活动正常... 详细信息

一、引言2022年,日本央行前行长黑田东彦在日本经济团体联合会(Keidanren)会议上指出,日本“正在接近打破长期低通胀和低增长的关键时刻”。回首望去,2023年的确是朝着转型迈进的一年。日本经济已转向温和复苏,主要体现在经济活动正常化、供给侧约束减弱,产出缺口已改善至0%左右。以消费者价格指数(CPI)衡量的日本通胀率持续超过2%,这主要是由于过去进口价格上涨传递至消费价格.

关键词：供给侧产出缺口消费价格日本央行通胀率低通胀黑田东彦工资

Development of an Accurate Urban Modeling System Using CAD/GIS Data for Atmosphere Environmental Simulation

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Tsinghua Science and Technology 2008年第S1期13卷 412-417页

作者： Tomosato Takada kazuo Kashiyama Department of Civil Engineering Chuo University

This paper presents an urban modeling system using CAD/GIS data for atmosphere environmental simulation, such as wind flow and contaminant spread in urban area. The CAD data is used for the shape modeling for the high-storied buildings and civil structures with complicated shape since the data for that is not included in the 3D-GIS data accurately. The unstructured mesh based on the tetrahedron element is employed in order to express the urban structures with complicated shape accurately. It is difficult to understand the quality of shape model and mesh by the conventional visualization technique. In this paper, the stereoscopic visualization using virtual reality (VR) technology is employed for the verification of the quality of shape model and mesh. The present system is applied to the atmosphere environmental simulation in urban area and is shown to be an useful planning and design tool to investigate the atmosphere environmental problem.

关键词： CAD/GIS urban modeling mesh generation atmosphere environmental simulation stereo-scopic visualization virtual reality