检索结果-南通市图书馆

Unsteady Operation of New Type Turbofan Engine with Aerodynamic Torque Converter Reducing Front Fan Speed

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2005年第3期14卷 206-210页

作者： Toshiaki KANEMOTO Seita SEKI kazunori IDENO Ahmed Mohamed GALAL Kyushu Institute of Technology Sensui 1-1 Tobata Kitakyushu 804-8550 Japan ProfessorKyushu Institute of Technology Sensui 1-1 Tobata Kitakyushu 804-8550 JapanKyushu Institute of Technology Sensui 1-1 Tobata Kitakyushu 804-8550 JapanKyushu Institute of Technology Sensui 1-1 Tobata Kitakyushu 804-8550 Japan

It is desired to increase the rotational speed of the core engine of the turbofan so as to get the best efficiency for the next leap of engine technology. The conventional mechanism in which the front fan is directly connected to the output shaft of a core engine, have a limit of increasing the spool speed, because the fan diameter is very large. The authors have proposed a new driving system in which the front fan is driven through the aerodynamic torque converter. The front fan can work at the best performance at slower speed while the core engine runs more efficiently at higher speed. Continuously, this paper discusses the response of the front fan in the unsteady operation of the core engine, accompanying with the internal flow. The system has the acceptable responsibility in the unsteady operation which is very important for the aircrafts.

关键词：涡轮发动机空气动力学鼓风机转动速度

Interaction of activity involvement and recreational location selection behavior in Lowland City:A case study of public parks in Saga City,Japan

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2005年第8期6卷 900-906页

作者： IAMTRAKUL Pawinee TEKNOMO Kardi GE Jian HOKAO kazunori Department of Civil Engineering Saga University Saga 840-8502 Japan Institute of Lowland Technology Saga University Saga 840-8502 Japan Department of Architecture Zhejiang University Hangzhou 310058 China

Public parks provide many benefits to the community as the representatives of green area. The allocation of public places plays an extremely important role in the daily lives of inhabitants especially for recreational use that could enhance the quality of life of residents in the vicinity. To understand park users’ behavior is one of the most important prerequisites for as-sessing the participation in public service from the park users’ point of view. The pattern of park utilization on location and activity selection are important elements in behavioral study, while the public parks topograph may also influence the typical user’s be-havior. Questionnaire survey on park utilization was used to investigate the interaction between activity involvement and recrea-tional location with the use of linear discriminant analysis (LDA) model. The study found that public park users’ behavior is influenced not only by social characteristics but also by the recreational activities and their specific location characteristics. We found that about 45 percent of park visitors are local residents living within a radius of 3 km preferred travel to parks near their residential area. This implies that location selection behavior is correlated with travel distance, travel time and travel cost. Visit frequencies and on site expenditures reflect the recreation behavior for different type of activities. The overall information can be usefully applied by decision makers to launch appropriate public policy in consistence with the useful results of this study.

关键词：城市规划公园设计生活质量环境评估

Temporal adjustment of short calls according to a partner during vocal turn-taking in Japanese macaques

在线全文

学校读者我要写书评

暂无评论

Current Zoology 2019年第1期65卷 99-105页

作者： Noriko KATSu kazunori Yamada Kazuo Okanoya Masayuki Nakamichi Graduate School of Arts and Sciences The University of Tokyo Meguro Tokyo Japan Graduate School of Human Sciences Osaka University Suita Osaka Japan Japan Society for the Promotion of Science Tokyo Japan

Turn-taking is a common feature in human speech, and is also seen in the communication of other primate species. However, evidenee of turn-taking in vocal exchanges within a short time frame is still scarce in non human primates. This study in vestigated whether dynamic adjustme nt during turn-taking in short calls exists in Japanese macaques Macaca fuscata. We observed exchanges of short calls such as grunts, girneys, and short, low coos during social interactions in a free-ranging group of Japanese macaques. We found that the median gap between the turns of two callers was 250 ms. Call intervals varied among individuals, suggesting that call intervals were not fixed among individuals. Solo call intervals were shorter than call intervals interrupted by responses from partn ers (i.e., excha nges) and Ion ger than those between the partner's reply and the reply to that call, indicating that the monkeys did not just repeat calls at certain intervals irrespective of the social situation. The differences in call intervals during exchanged and solo call sequences were explained by the response interval of the partner, suggesting an adjustment of call timing according to the tempo of the part ner's call utterance. These findi ngs suggest that mon keys display dyn amic temporal adjustment in a short time window, which is comparable with turn-taking in human speech.

关键词： turn-taking rhythm vocalization primate

Beneficial effects of fucoidan in patients with chronic hepatitis C virus infection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2012年第18期18卷 2225-2230页

作者： Naoki Mori kazunori Nakasone Koh Tomimori Chie Ishikawa Department of Microbiology and Oncology Graduate School of MedicineUniversity of the RyukyusNishiharaOkinawa 903-0215Japan Nakasonekazu Medical Clinic NahaOkinawa 902-0062Japan Department of Psychiatry Naha City HospitalNahaOkinawa 902-8511Japan Transdisciplinary Research Organization for Subtropics and Island Studies University of the RyukyusNishiharaOkinawa 903-0213Japan

AIM:To evaluate the effects of fucoidan,a complex sulfated polysaccharide extract from marine seaweed,on hepatitis C virus(HCV) RNA load both in vitro and in ***:HCV-1b replicon-expressing cells were cultured in the presence of fucoidan obtained from Cladosiphon okamuranus Tokida cultivated in Okinawa,Japan,and quantified the level of HCV *** an open-label uncontrolled study,15 patients with chronic hepatitis C,and HCV-related cirrhosis and hepatocellular carcinoma were treated with fucoidan(0.83 g/d) for 12 *** clinical symptoms,biochemical tests,and HCV RNA levels were assessed before,during,and after ***:Fucoidan dose-dependently inhibited the expression of HCV *** 8-10 mo of treatment with fucoidan,HCV RNA levels were significantly lower relative to the *** same treatment also tended to lower serum alanine aminotransferase levels,and the latter correlated with HCV RNA ***,the improved laboratory tests did not translate into significant clinical *** had no serious adverse ***:Our findings suggest that fucoidan is safe and useful in the treatment of patients with HCVrelated chronic liver *** controlled clinical trials are needed to confirm the present findings.

关键词：褐藻多糖硫酸酯丙型肝炎病毒有益作用病毒感染慢性患者海藻硫酸多糖临床症状

A Brief Review of Bone Adaptation to Unloading

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genomics, Proteomics & Bioinformatics 2008年第1期6卷 4-7页

作者： kazunori Hamamura Hiroki Yokota Department of Biomedical Engineering/Department of Anatomy and Cell Biology Indiana University-Purdue University IndianapolisIndianapolis IN 46202 USA

Weight-bearing bone is constantly adapting its structure and function to mechanical environments. Loading through routine exercises stimulates bone formation and prevents bone loss, but unloading through bed rest and cast immobilization as well as exposure to weightlessness during spaceflight reduces its mass and strength. In order to elucidate the mechanism underlying unloading-driven bone adaptation, ground-based in vitro and in vivo analyses have been conducted using rotating cell culturing and hindlimb suspension. Focusing on gene expression studies in osteoblasts and hindlimb suspension studies, this minireview introduces our recent understanding on bone homeostasis under weightlessness in space. Most of the existing data indicate that unloading has the opposite effects to loading through common signaling pathways. However, a question remains as to whether any pathway unique to unloading （and not to loading） may exist.

关键词： weightlessness unloading osteocytes

Computer support system for residential environment evaluation for citizen participation

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2005年第8期6卷 894-899页

作者：葛坚蒋介德陆江 HOKAO kazunori Department of Architecture Zhejiang University Institute of Lowland Technology Saga University Department of Civil Engineering Zhejiang University of Science and Technology Department of Civil Engineering Saga University Saga 840-8506 Japan

Though the method of citizen participation in urban planning is quite well established, for a specific segment of residential environment, however, existing participation system has not coped adequately with the issue. The specific residential environment has detailed aspects that need positive and high level involvement of the citizens in participating in all stages and every field of the plan. One of the best and systematic methods to obtain a more involved citizen is through a citizen workshop. To get a more “educated” citizen who participates in the workshop, a special session to inform the citizen on what was previously gathered through a survey was revealed to be prerequisite before the workshop. The computer support system is one of the best tools for this purpose. This paper describes the development of the computer support system for residential environment evaluation system, which is an essential tool to give more information to the citizens before their participation in public workshop. The significant contribution of this paper is the educational system framework involved in the workshop on the public participation system through computer support, especially for residential environment. The framework, development and application of the computer support system are described. The application of a workshop on the computer support system was commented on as very valuable and helpful by the audience as it resulted in greater benefit to have wider range of participation, and deeper level of citizen understanding.

关键词：住宅环境评估市民参与计算机支持系统城市规划公共平台

Machine learning adaptation of intraocular lens power calculation for a patient group

在线全文

学校读者我要写书评

暂无评论

Eye and Vision 2021年第5期8卷 422-430页

作者： Yosai Mori Tomofusa Yamauchi Shota Tokuda Keiichiro Minami Hitoshi Tabuchi kazunori Miyata Miyata Eye Hospital 6‑3 Kurahara‑choMiyakonojoMiyazaki 885‑0051Japan Department of Ophthalmology Tsukazaki Hospital68‑1 WakuAboshi‑kuHimejiHyogo 671‑1227Japan Department of Technology and Design Thinking for Medicine Hiroshima University1‑2‑3 KasumiMinami‑kuHiroshima 734‑8553Japan

Background:To examine the effectiveness of the use of machine learning for adapting an intraocular lens(IOL)power calculation for a patient ***:In this retrospective study,the clinical records of 1,611 eyes of 1,169 Japanese patients who received a single model of monofocal IOL(SN60WF,Alcon)at Miyata Eye Hospital were reviewed and *** biometric metrics and postoperative refractions of 1211 eyes of 769 patients,constants of the SRK/T and Haigis formulas were *** SRK/T formula was adapted using a support vector *** errors in the use of adapted formulas as well as the SRK/T,Haigis,Hill-RBF and Barrett Universal II formulas were evaluated with data from 395 eyes of 395 distinct *** prediction errors,median absolute errors,and percentages of eyes within±0.25 D,±0.50 D,and±1.00 D,and over+0.50 D of errors were compared among ***:The mean prediction errors in the use of the SRT/K and adapted formulas were smaller than the use of other formulas(P<0.001).In the absolute errors,the Hill-RBF and adapted methods were better than *** performance of the Barrett Universal II was not better than the others for the patient *** were the least eyes with hyperopic refractive errors(16.5%)in the use of the adapted ***:Adapting IOL power calculations using machine learning technology with data from a particular patient group was effective and promising.

关键词： Machine learning Adaptation Intraocular lens power calculation Patient ethnicity Patient race Region of patient SRK/T formula

Studies of nanoparticle delivery with in vitro bio-engineered microtissues

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2020年第4期5卷 924-937页

作者： Mingze Sun Jinhyung Lee Yupeng Chen kazunori Hoshino Department of Biomedical Engineering University of Connecticut260 Glenbrook RdStorrsCT06269USA

A variety of engineered nanoparticles,including lipid nanoparticles,polymer nanoparticles,gold nanoparticles,and biomimetic nanoparticles,have been studied as delivery vehicles for biomedical *** assessing the efficacy of a nanoparticle-based delivery system,in vitro testing with a model delivery system is crucial because it allows for real-time,in situ quantitative transport analysis,which is often difficult with in vivo animal *** advent of tissue engineering has offered methods to create experimental models that can closely mimic the 3D microenvironment in the human *** review paper overviews the types of nanoparticle vehicles,their application areas,and the design strategies to improve delivery efficiency,followed by the uses of engineered microtissues and methods of *** particular,this review highlights studies on multicellular spheroids and other 3D tissue engineering approaches for cancer drug *** use of bio-engineered tissues can potentially provide low-cost,high-throughput,and quantitative experimental platforms for the development of nanoparticle-based delivery systems.

关键词： Nanoparticles Drug delivery In vitro tissue model Multicellular spheroid

Enhancing mechanism of intestinal absorption of highly lipophilic compounds using microemulsion e Quantitative analysis of the partitioning to the mesenteric lymph in intestinal cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2015年第3期10卷 186-193页

作者： kazunori Iwanaga Yoichi Higashiyama Makoto Miyazaki Masawo Kakemi Division of Pharmaceutics Osaka University of Pharmaceutical Sciences4-20-1 NasaharaTakatsukiOsaka 569-1094Japan

The purpose of this study was to quantify the effect of the fatty acid alkyl-chain length of a polyethylene glycol(PEG)glyceryl ester,which was used as a microemulsion oil component,on the partitioning of highly lipophilic compounds to the mesenteric lymph after oral *** blue N,a highly lipophilic anthraquinone derivative,was orally administered to lymph duct-cannulated and untreated rats in two kinds of different ***®50/13 and Gelucire®44/14 were used as the oil component with long chain and medium chain fatty acid portions,respectively,of PEG glyceryl esters in *** cumulative amount of oil blue N in lymph fluid was almost the same between the two microemulsions,although the transferred amount of oil component(triglyceride)in the lymph after administration of the Gelucire®50/13 microemulsion was significantly higher than that of the Gelucire®44/14 *** the other hand,the solubility of oil blue N in Gelucire®44/14 was much higher than that in Gelucire®50/*** significant differences were observed between microemulsions in the bioavailability of oil blue *** these data,the partitioning of oil blue N to the lymph was calculated using a mathematical model,showing that the partitioning ratios of oil blue N to the lymph fluid were almost the same for both *** solubility of oil blue N to the oil component of the microemulsions and the transfer of triglycerides to the lymph after administration of the microemulsions counteract each other,leading to similar partitioning ratios of oil blue N to the lymph.

关键词： Microemulsion Intestinal absorption Mesenteric lymph Partition Quantitative analysis