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A New Technique for Leakage Reduction in 65 nm Footerless Domino Circuits

Circuits and Systems 2013年第2期4卷 209-216页

作者： Tarun Kumar Gupta kavita khare Department of Electronics & Communication Maulana Azad National Institute of Technology Bhopal India

A new circuit technique for 65 nm technology is proposed in this paper for reducing the subthreshold and gate oxide leakage currents in idle and non idle mode of operation for footerless domino circuits. In this technique a p-type and an n-type leakage controlled transistors (LCTs) are introduced between the pull-up and pull-down network and the gate of one is controlled by the source of the other. For any combination of input, one of the LCT will operate near its cut off region and will increase the resistance between supply voltage and ground resulting in reduced leakage current. Furthermore, the leakage current is suppressed at the output inverter circuit by inserting a transistor below the n-type transistor of the inverter offering more resistive path between supply voltage and ground. The proposed technique is applied on benchmark circuits reduction of active power consumption is observed from 10.9% to 44.76% at different temperature variations. For same benchmark circuits, operating at two clock modes and giving low and high inputs at 25℃ and 110℃ temperatures the maximum leakage power saving of 98.9% is achieved when compared to standard footerless domino logic circuits.

关键词： Footerless Domino Logic Subthreshold Leakage Gate Oxide Tunneling Leakage Current

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A Novel High-Performance Lekage-Tolerant, Wide Fan-In Domino Logic Circuit in Deep-Submicron Technology

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Circuits and Systems 2015年第4期6卷 103-111页

作者： Ajay Dadoria kavita khare T. K. Gupta R. P. Singh Electronics & Communication Engineering MANIT Bhopal India

As technology shrinks in modern era the demand on high speed, low power consumption and small chip area in microprocessors is come into existence. In this paper we have presented a new class of domino circuit design for low power consumption, faster circuit speed and high performance. Due to wide fan-in domino logic, its logic gate suffer from noise sensitivity, if we improve sensitivity, sub-threshold and gate oxide leakage current dominate in evaluation network, which increases the power consumption and reduces the performance of the circuit. The proposed circuit improves the dynamic power consumption and reduces the delay which improves the speed of the circuit. Simulation is performed in BISM4 Cadence environment at 65 nm process technology, with supply voltage 1 V at 100 MHz frequency and bottleneck operating temperature of 27°C with CL = 1 fF. From the result average power improvement by proposed circuit 1 & 2 for 8 input OR gate is 10.1%, 15.28% SFLD, 48.56%, 51.49% CKD, 55.17%, 57.71% HSD and improvement of delay is 1.10%, 12.76% SFLD, 19.13%, 28.63% CKD, 4.32%, 15.59% HSD, 19.138%, 44.25% DFD respectively.

关键词： High Speed Integrated Circuit Dynamic Logic Circuit Unity Noise Gain (UNG) Domino Logic Circuit Noise Immunity

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Unique case of oligoastrocytoma with recurrence and grade progression:Exhibiting differential expression of high mobility group-A1 and human telomerase reverse transcriptase

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World Journal of Clinical Cases 2016年第9期4卷 296-301页

作者： Puneet Gandhi Richa khare kavita Niraj Nitin Garg Sandeep K Sorte Hanni Gulwani Department of Research Bhopal Memorial Hospital and Research Centre Department of Neurosurgery Bhopal Memorial Hospital and Research Centre and Bansal Hospital Department of Pathology Bhopal Memorial Hospital and Research Centre

Mixed gliomas, primarily oligoastrocytomas, account for about 5%-10% of all gliomas. Distinguishing oligoastrocytoma based on histological features alone has limitations in predicting the exact biological behavior, necessitating ancillary markers for greater specificity. In this case report, human telomerase reverse transcriptase(hT ERT) and high mobility group-A1(HMGA1); markers of proliferation and stemness, have been quantitatively analyzed in formalin-fixed paraffin-embedded tissue samples of a 34 years old patient with oligoastrocytoma. Customized florescence-based immunohistochemistry protocol with enhanced sensitivity and specificity is used in the study. The patient presented with a history of generalized seizures and his magnetic resonance imaging scans revealed infiltrative ill-defined mass lesion with calcified foci within the left frontal white matter, suggestive of glioma. He was surgically treated at our center for four consecutive clinical events. Histopathologically, the tumor was identified as oligoastrocytoma-grade Ⅱ followed by two recurrence events and final progression to grade Ⅲ. Overall survival of the patient without adjuvant therapy was more than 9 years. Glial fibrillary acidic protein, p53, Ki-67, nuclear atypia index, pre-operative neutrophillymphocyte ratio, are the other parameters assessed. Findings suggest that hT ERT and HMGA1 are linked to tumor recurrence and progression. Established markers can assist in defining precise histopathological grade in conjuction with conventional markers in clinical setup.

关键词： Human telomerase reverse transcriptase High mobility group-A1 Oligoastrocytoma Recurrence Tumor grade

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