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Chinese Journal of Catalysis 2017年第11期38卷 1918-1924页

作者： R. D. Padmaja Sourav Rej kaushik chanda Department of Chemistry School of Advanced Sciences VIT University Vellore‐632014 India Institute of Bioengineering and Nanotechnology A*STAR. 31 Biopolis Way Singapore‐138669

Recyclable CuO nanoparticles were successfully employed to catalyze the microwave‐assisted(3+2)cycloaddition reaction between nitriles and NaN3to efficiently synthesize5‐substituted1H‐*** salient features associated with this protocol are its cost effectiveness,rapid synthesis,stability,reusability,mild reaction conditions without any additives,high tolerance to various functional groups,and excellent yields under microwave *** environmentally friendly,microwave‐assisted,nanoparticle‐catalyzed synthetic methodology is seen as an alternative to conventional procedures that involve Lewis acid catalysts and a simple operation to the privileged scaffold.

关键词： Tetrazoles CuO nanoparticles (3+2) cycloaddition Green chemistry Microwave irradiation

Smart electrochemical sensing of amyloid-beta to manage total Alzheimer's diseases

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Neural Regeneration Research 2024年第6期19卷 1185-1186页

作者： Ajeet kaushik NanoBioTech Laboratory Department of Environmental EngineeringFlorida Polytechnic UniversityLakelandFLUSA School of Engineering University of Petroleum and Energy Studies(UPES)DehradunIndia

Need for Alzheimer's disease progression monitoring:Alzheimer's disease(AD)is an irreversible progressive brain disorder that causes severe and incurable *** World Health Organization estimates that 55 million people are affected by AD dementia by 2020 which may exceed 78 million by 2030 and 139 in *** estimated cost to manage AD is above US$1.3 trillion,which will further increase to US$2.8 trillion by 2030.

关键词： Alzheimer amyloid diseases

Sequential decay analysis of^(235)U(n^(th),f)reaction using fragmentation approach

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Chinese Physics C 2024年第6期48卷 145-154页

作者： Nitin Sharma Ashutosh kaushik Manoj K.Sharma School of Physics and Materials Science Thapar Institute of Engineering&TechnologyPatiala-147004PunjabIndia

Numerous experimental and theoretical observations have concluded that the probability of the three fragment emission(ternary fission)or binary fission increases when one proceeds towards the heavy mass region of nuclear periodic *** factors affect fragment emission,such as the shell effect,deformation,orientation,and fissility *** and ternary fissions are observed for both ground and excited states of the *** collinear cluster tripartition(CCT)channel of the^(235)U(n^(th),f)reaction is studied,and we observe that the CCT may be a sequential or simultaneous emission *** date,different approaches have been introduced to study the CCT process as a simultaneous or sequential process,but the decay dynamics of these modes have not been not fully *** the three fragments of the sequential process and exploring their related dynamics using an excitation energy dependent approach would be of further ***,in this study,we investigate the sequential decay mechanism of the^(235)U(n^(th),f)reaction using quantum mechanical fragmentation theory(QMFT).The decay mechanism is considered in two steps,where initially,the nucleus splits into an asymmetric *** the second step,the heavy fragment obtained in the first step divides into two *** I analysis is conducted by calculating the fragmentation potential and preformation probability for the spherical and deformed choices of the decaying *** most probable fragment combination of stage I are identified with respect to the dips in the fragmentation structure and the corresponding maxima of the preformation probability(P0).The light fragments of the identified decay channels(obtained in step I)agree closely with the experimentally observed *** excitation energy of the decay channel is calculated using an iteration *** excitation energy is shared using an excitation energy dependent level density *** obtained excitation

关键词： fission cluster radioactivity ternary fission spontaneous fission cluster model total kinetic energy preformation probability

Effect of pre-twinning and heat treatment on formability of AZX311 Mg alloy

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Journal of Magnesium and Alloys 2024年第3期12卷 1154-1169页

作者： Mahesh Panchal Lalit kaushik Min-Seong Kim Ravi Kottan Renganayagalu Shi-Hoon Choi Jaiveer Singh Department of Mechanical Engineering Indian Institute of Technology JodhpurKarwarJodhpur 342030RajasthanIndia Department of Metallurgical and Materials Engineering Indian Institute of Technology JodhpurKarwarJodhpur 342030RajasthanIndia Energy Materials Research Center Korea Institute of Science and Technology(KIST)5 Hwarang-roSeongbuk-guSeoul 02792Republic of Korea Department of Advanced Components and Materials Engineering Sunchon National University255 Jungang-roSuncheonJeonnam 57922Republic of Korea

In this study,the effects of pre-strain-induced tensile twins(TTWs)and controlled heat treatment on the formability behavior of AZX311 Mg alloy sheets were investigated.A 4%compressive strain was applied to pre-strain the sheets using the in-plane compression(IPC)technique along the rolling direction(RD)to introduce *** pre-strained(PS)samples were subsequently heat-treated at 250℃,350℃,and 400℃ independently for 1 hr,and are termed as PSA1,PSA2,and PSA3,*** cupping tests were conducted to assess the formability of the sheet samples under different initial *** results showed that the PS sample heat-treated at 250℃ for 1hr exhibited a decrease in the Erichsen index(IE)compared to the as-rolled sample,whereas PSA2 and PSA3 samples showed an increase in IE *** analysis revealed that most of the TTWs generated through pre-twinning were stable at 250℃;however,the twin volume fraction reduced to 41%at 350℃ compared to the PS samples due to enhanced thermal activity at that ***,PSA2 samples showed severe grain coarsening in some areas of the sample,and the fraction of such grains increased in the PSA3 *** stretch formability(IE value)of PSA2 samples showed a 32.3%increase compared to the as-rolled ***,the analysis of the deformed specimen at failure under the Erichsen test indicated that considerable detwinning occurs in the PS and PSA1 samples,whereas dislocation slip activity dominates in the PSA2 and PSA3 samples during stretch *** from detwinning and dislocation slip,deformation twins were also observed in all samples after the Erichsen ***,this work highlights the importance of texture control and its underlying mechanisms via pre-twinning followed by heat treatment and their impact on the room temperature(RT)stretch formability of AZX311 Mg alloy sheets.

关键词： Mg alloys Pre-twinning Texture Formability EBSD.

Machine Learning Techniques Using Deep Instinctive Encoder-Based Feature Extraction for Optimized Breast Cancer Detection

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Computers, Materials & Continua 2024年第2期78卷 2441-2468页

作者： Vaishnawi Priyadarshni Sanjay Kumar Sharma Mohammad Khalid Imam Rahmani Baijnath kaushik Rania Almajalid Department of Computer Science Gautam Buddha UniversityGreater NoidaUttar PradeshIndia College of Computing and Informatics Saudi Electronic UniversityRiyadh11673Saudi Arabia School of Computer Science Shri Vaishno Devi UniversityKatraIndia

Breast cancer(BC)is one of the leading causes of death among women worldwide,as it has emerged as the most commonly diagnosed malignancy in *** detection and effective treatment of BC can help save women’s *** an efficient technology-based detection system can lead to non-destructive and preliminary cancer detection *** paper proposes a comprehensive framework that can effectively diagnose cancerous cells from benign cells using the Curated Breast Imaging Subset of the Digital Database for Screening Mammography(CBIS-DDSM)data *** novelty of the proposed framework lies in the integration of various techniques,where the fusion of deep learning(DL),traditional machine learning(ML)techniques,and enhanced classification models have been deployed using the curated *** analysis outcome proves that the proposed enhanced RF(ERF),enhanced DT(EDT)and enhanced LR(ELR)models for BC detection outperformed most of the existing models with impressive results.

关键词： Autoencoder breast cancer deep neural network convolutional neural network image processing machine learning deep learning

High Power Microwave Treatment Impacts on Microbes in Rough Rice

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Rice science 2024年第2期31卷 139-141,I0020,I0021页

作者： Faith OUMA Luthra kaushik Boreddy SREENIVASULA Oduola ABASS Griffiths G.ATUNGULU Department of Food Science University of Arkansas Division of AgricultureFayetteville 72704USA Department of Processing and Food Engineering Dr.NTR College of Agricultural EngineeringBapatla 522101India

As rice consumption increases,ensuring its safety has become a priority for the food *** address this concern,the industry is exploring a single-pass microbial inactivation treatment at the rough rice *** this study,a long-grain rice variety,RT7321[21.2%wet basis(WB)and a 20 mm bed thickness]was exposed to microwave radiation(915 MHz frequency)at powers of 16,18,and 20 kW for durations of 1,2,and 3 *** found that the highest microwave power(20 kW)and the longest exposure duration(3 min)produced the greatest reduction in total aerobic count and total fungal count,reducing them by up to 1.21 and 5.01 log(CFU/g),*** findings provided insights into the used to high-power,shortduration 915 MHz microwave technology for decontamination purposes in rough rice to help improve the microbial safety of *** aim is to develop a single-pass drying approach for microbial inactivation in rice processing facilities while ensuring that the yield and quality is not compromised.

关键词： microwave insight facilities

Targeting brain tumors with innovative nanocarriers:bridging the gap through the blood-brain barrier

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Oncology Research 2024年第5期32卷 877-897页

作者： KARAN WADHWA PAYAL CHAUHAN SHOBHIT KUMAR RAKESH PAHWA RAVINDER VERMA RAJAT GOYAL GOVIND SINGH ARCHANA SHARMA NEHA RAO DEEPAK kaushik Department of Pharmaceutical Sciences Maharshi Dayanand UniversityRohtak124001India Department of Pharmaceutical Technology Meerut Institute of Engineering and Technology(MIET)NH-58Delhi-Roorkee HighwayMeerut250005India Institute of Pharmaceutical Sciences Kurukshetra UniversityKurukshetra136119India Department of Pharmaceutical Sciences Chaudhary Bansi Lal UniversityBhiwani127021India MM College of Pharmacy Maharishi Markandeshwar(Deemed to be University)Mullana-AmbalaHaryana133207India Delhi Pharmaceutical Sciences and Research University(DIPSAR) Delhi Pharmaceutical Sciences and Research UniversityNew Delhi110017India

Background:Glioblastoma multiforme(GBM)is recognized as the most lethal and most highly invasive *** high likelihood of treatment failure arises fromthe presence of the blood-brain barrier(BBB)and stemcells around GBM,which avert the entry of chemotherapeutic drugs into the ***:Recently,several researchers have designed novel nanocarrier systems like liposomes,dendrimers,metallic nanoparticles,nanodiamonds,and nanorobot approaches,allowing drugs to infiltrate the BBB more efficiently,opening up innovative avenues to prevail over therapy problems and radiation ***:Relevant literature for this manuscript has been collected from a comprehensive and systematic search of databases,for example,PubMed,Science Direct,Google Scholar,and others,using specific keyword combinations,including“glioblastoma,”“brain tumor,”“nanocarriers,”and several ***:This review also provides deep insights into recent advancements in nanocarrier-based formulations and technologies for GBM *** of various scientific advances in conjunction with encouraging findings concerning the future perspectives and challenges of nanocarriers for effective brain tumor management has also been discussed.

关键词： Glioblastoma Brain tumor Blood-brain barrier Liposomes Metallic nanoparticles Nanocarriers

Assessment of the environmental kuznets curve within EU-27:Steps toward environmental sustainability(1990-2019)

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Environmental Science and Ecotechnology 2024年第2期18卷 91-103页

作者： Safwan Mohammed Abid Rashid Gill kaushik Ghosal Main Al-Dalahmeh Karam Alsafadi Szilárd Szabó Judit Oláh Ali Alkerdi Akasairi Ocwa Endre Harsanyi Institute of Land Use Engineering and Precision Farming TechnologyFaculty of Agricultural and Food Sciences and Environmental ManagementUniversity of DebrecenBöszörményi 138H-4032DebrecenHungary Institutes for Agricultural Research and Educational Farm University of DebrecenBöszörményi 138H-4032DebrecenHungary Department of Economics The Islamia University of BahawalpurPakistan Department of Mining Engineering Indian Institute of Engineering Science and TechnologyShibpurP.O.711103Botanic GardenHowrahWest Bengal711103India Institute of Management and Organization Sciences Faculty of Economics and BusinessUniversity of DebrecenEgyetem Tér 14032DebrecenHungary School of Geographical Sciences Nanjing University of Information Science and TechnologyNanjing210044China Department of Physical Geography and Geoinformatics Faculty of Sciences and TechnologyUniversity of DebrecenEgyetem tér 14032DebrecenHungary Faculty of Economics and Business University of Debrecen4032DebrecenHungary Department of Trade and Finance Faculty of Economics and ManagementCzech University of Life SciencesPrague16500PragueCzech Republic Department of Agricultural Economics Faculty of AgricultureKahramanmaras SütçüImam UniversityTurkey Department of Agriculture Production Faculty of AgricultureKyambogo University P.O.B.1KyambogoKampalaUganda

Reducing environmental pollution is a critical goal in global environmental economics and economic *** European Union(EU)faces environmental challenges due to its development *** we present a comprehensive approach to assess the impact of carbon dioxide(CO_(2))emissions,energy consumption(EC),population structure(POP),economy(GDP),and policies on the environment within the EU using the environmental Kuznets curve(EKC).Our research reveals that between 1990 and 2019,the EU-27 experienced an increase of t1.18 million tonnes of oil equivalent(Mtoe)per year in energy consumption(p<0.05),while CO_(2)emissions decreased by 24.25 million tonnes(Mt)per year(p<0.05).The highest reduction in CO_(2)emissions occurred in Germany(7.52 Mt CO_(2)annually),and the lowest in Latvia(0.087 Mt CO_(2)annually).The empirical EKC analysis shows an inverted-U shaped relationship between GDP and CO_(2)emissions in the ***,a 1%increase in GDP results in a 0.705%increase in carbon emission,while a 1%increase in GDP2 leads to a 0.062%reduction in environmental pollution in the long run(p<0.01).These findings indicate that economic development within the EU has reached a stage where economic growth positively impacts the ***,this study provides insights into the effectiveness of environmental policies in mitigating degradation and promoting green growth in the EU 27 countries.

关键词： Invasion risk Climate change Adaptive genomic variation Genomic offset Habitat suitability

Effect of ankle versus thigh tourniquets on post-operative pain in foot and ankle surgery

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World Journal of Orthopedics 2024年第2期15卷 163-169页

作者： Ashish Mishra Ahmed Barakat Jitendra Mangwani Jakub Kazda Sagar Tiwatane Sana Mohammed Aamir Shaikh Linzy Houchen-Wolloff Vipul kaushik Department of Trauma and Orthopedics University Hospitals LeicesterLeicester LE15WWUnited Kingdom Department of Trauma and Orthopedics Leicester University Hospitals-NHS TrustLeicester LE15WWLeicestershireUnited Kingdom Academic Team of Musculoskeletal Surgery University Hospitals of Leicester NHS TrustLeicester LE39QPUnited Kingdom Department of Anaesthesia York&Scarborough Teaching Hospitals NHS Foundation TrustNorth Yorkshire YO318HEUnited Kingdom Department of Anaesthesia Royal Free London NHS TrustLondon NW32QGUnited Kingdom Department of Trauma&Orthopaedics Breach Candy Hospital TrustMumbai 400026India Department of Physiotherapy University Hospitals of Leicester NHS TrustLeicester LE39QPUnited Kingdom Department of Anasthesia University Hospitals of Leicester NHS TrustLeicester LE15WWUnited Kingdom

BACKGROUND Tourniquets are commonly used in elective extremity orthopaedic surgery to reduce blood loss,improve visualization in the surgical field,and to potentially reduce surgical *** is a lack of consensus in existing guidelines regarding the optimal tourniquet pressure,placement site,and duration of *** is a paucity of data on the relationship between the site of a tourniquet and postoperative pain in foot and ankle *** To explore the relationship between tourniquet site and intensity of post-operative pain scores in patients undergoing elective foot and ankle *** Retrospective analysis of prospectively collected data on 201 patients who underwent foot and ankle surgery in a single institution was *** tourniquet duration,tourniquet pressure and site,and postoperative pain scores using Visual Analogue Score were collected in immediate recovery,at six hours and at 24 h *** plots were used to analyse the data and to assess for the statistical correlation between tourniquet pressure,duration,site,and pain scores using Pearson correlation *** All patients who underwent foot and ankle surgery had tourniquet pressure of 250 mmHg for ankle tourniquet and 300 mmHg for *** was no correlation between the site of the tourniquet and pain scores in recovery,at six hours and after 24 *** was a weak correlation between tourniquet time and Visual Analogue Score immediately post-op(r=0.14,P=0.04)but not at six or 24 h *** This study shows that there was no statistically significant correlation between tourniquet pressure,site and postop pain in patients undergoing foot and ankle *** choice of using a tourniquet is based on the surgeon's preference,with the goal of minimizing the duration of its application at the operative site.

关键词： Lower limb surgery Tourniquet time Tourniquet pressure Tourniquet site Post-operative pain Pain scores

Development of a Tribofidelic Human Heel Surrogate for Barefoot Slip Testing

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Journal of Bionic Engineering 2022年第2期19卷 429-439页

作者： Subhodip Chatterjee Arnab chanda Centre for Biomedical Engineering Indian Institute of Technology DelhiNew Delhi 110016India Department of Biomedical Engineering All India Institute of Medical ScienceNew Delhi 110029India

Barefoot slips contribute to over 37% of recurrent fall-related injuries across all age *** study slip risk across a wide range of flooring conditions,slip meters with barefoot surrogates(i.e.,sensors,as per ASTM standard nomenclature)such as animal skins and rubbers have been used to date,which exhibit biomechanical and frictional properties widely different from the barefoot human *** of a surrogate which can accurately simulate the human heel skin properties would be immensely beneficial for realistic assessment of barefoot slipping risk.A novel surrogate was developed using 3D scanning and printing,and biomimetics,which precisely simulates the biomechanical and frictional properties of the barefoot human heel *** slip testing was conducted with this surrogate on three common bathroom floorings and with six different *** of Friction(COF)results similar to human slipping experiments,high repeatability and reproducibility across wet and oily flooring conditions,were confirmed through experiments with the developed heel skin *** heel skin surrogate would be an indispensable model for accurate estimation of barefoot risk against slips and falls in bathrooms,bathtubs,and swimming pools.

关键词： Barefoot Surrogate Slip Fall Bathroom Bathtub