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Association be.we.n He.icobacte. pylori infe.tion,mismatch re.air,He.2 and tumor-infiltrating lymphocyte. in gastric cance.

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World Journal of Gastrointe.tinal Oncology 2024年第6期16卷 2487-2503页

作者： Carlos A Castane.a Miluska Castillo Luis A Be.nabe.Jose.yn Sanche. Matte. Fassan katherine Te.lo Ignacio Ivan Wistuba Ivan Chave. Passiuri e.oy Ruiz Juve.al Sanche. Fe.nando Barre.a Danie. Valdivia Yaque.ine.Bazan Milagros Abad-Licham Claudio Me.goa Hugo Fue.te. Paola Monte.e.ro e.e.t Poquioma Raul Alatrista Claudio J Flore. Luis Taxa Faculty of He.lth Scie.ce. Universidad Cientifica del SurLima 15038Peru Ge.O Pe.U Grupo de Estudios Clinicos Oncologicos del PeruLima 15038Peru De.artme.t of Re.e.rch Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Faculty of Human Me.icine Universidad Ricardo PalmaLima 15039Peru De.artme.t of Me.icine Surgical Pathology&Cytopathology UnitUniversity of PaduaPadua 35121Italy De.artme.t of Translational Mole.ular Pathology The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States De.artme.t of Abdominal Surge.y Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru De.artme.t of Pathology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru De.artme.t of Me.ical Spe.ialtie. Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru De.artme.t of Pathology Instituto Regional de Enfermedades Neoplasicas del NorteTrujillo 13001Peru Faculty of Human Me.icine Universidad Privada Antenor OrregoTrujillo 13008Peru De.artme.t of Surge.y Instituto Regional de Enfermedades Neoplasicas del SurArequipa 04002Peru De.artme.t of Me.ical Oncology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru De.artme.t of e.ide.iology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Unidad de.Inve.tigación Básica y Traslacional Oncosalud-AUNALima 15038Peru Faculty of Me.icine Universidad San Martin de PorresLima 15008Peru

BACKGROUND The.influe.ce.of He.icobacte.-pylori(***)infe.tion and the.characte.istics of gastric cance.(GC)on tumor-infiltrating lymphocyte.TIL)le.e.s has not be.n e.te.sive.y *** of infiltrating-immune.ce.l subtype. as we.l as survival is ne.e.sary to obtain compre.e.sive.*** To de.e.mine.the.rate. of de.icie.t mismatch-re.air(dMMR),He.2-status and *** infe.tion and the.r association with TIL le.e.s in *** Sample. from 503 re.e.te. GC tumors we.e.include. and TIL le.e.s we.e.e.aluate. following the.inte.national-TILs-working-group re.omme.dations with asse.sme.t of the.intratumoral(IT),stromal(ST)and invasive.borde.(IB)*** de.sity of CD3,CD8 and CD163 immune.ce.ls,and dMMR and He.2-status we.e.de.e.mine. by immunohistoche.istry(IHC).*** infe.tion was e.aluate. by routine.histology and quantitative.PCR(qPCR)in a subse. of *** dMMR was found in 34.4%,He.2+in 5%and ***-positive.in 55.7%of *** IT-TIL was associate. with grade.3(P=0.038),while.ST-TIL with grade.1(Pe.tinal-histology(Pe.urre.ce.P=0.003).dMMR was associate. with high TIL le.e.s in the.ST(P=0.019)and IB(P=0.01)compartme.ts,and STCD3(P=0.049)and ST-CD8(P=0.05)***2-was associate. with high IT-CD8(P=0.009).*** was associate. with high IT-TIL le.e.s(P=0.009)whe. asse.se. by routine.histology,and with high TIL le.e.s in the.3 compartme.ts(P=0.002-0.047)and CD8 de.sity in the.IT and ST compartme.ts(P=0.001)whe. asse.se. by qPCR.A longe. ove.all survival was associate. with low IT-CD163(P=0.003)and CD8/CD3(P=0.001 in IT and P=0.002 in ST)and high IT-CD3(P=0.021),ST-CD3(P=0.003)and CD3/CD163(P=0.002).CONCLUSION TIL le.e.s we.e.re.ate. to dMMR and *** CD8/CD3 and high CD163/CD3 we.e.associate. with lowe. re.urre.ce.and longe. survival.

关键词： Lymphocyte. Macrophage. Gastric cance. He.icobacte. pylori He.2 Mismatch re.air

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Surge.y for oligome.astasis of pancre.tic cance.

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Chine.e.Journal of Cance. Re.e.rch 2015年第4期27卷 358-367页

作者： Fe.gchun Lu katherine e.Poruk Matthe. J.We.ss De.artme.t of Ge.e.al Surge.y Union Hospital Fujian Medical University De.artme.t of Surge.y The Sol Goldman Pancreatic Cancer Research Center The Johns Hopkins University School of Medicine

The.incide.ce.of pancre.tic ade.ocarcinoma（PDAC） has ste.dily incre.se. ove. the.past se.e.al de.ade.. The.majority of PDAC patie.ts will pre.e.t with distant me.astase., limiting surgical manage.e.t in this population. He.ate.tomy and pulmonary me.astase.tomy（PM） has be.n we.l e.tablishe. for colore.tal cance. patie.ts with isolate., re.e.table.he.atic or pulmonary me.astatic dise.se. Re.e.t advance.e.ts in e.fe.tive.syste.ic the.apy for PDAC have.le. to the.se.e.tion of ce.tain patie.ts whe.e.me.aste.tomy may be.pote.tially indicate.. Howe.e., the.indication for re.e.tion of oligome.astase. in PDAC is not we.l de.ine.. This re.ie. will discuss the.curre.t lite.ature.on the.surgical manage.e.t of me.astatic dise.se.for PDAC with a spe.ific focus on surgical re.e.tion for isolate. he.atic and pulmonary me.astase..

关键词： Pancre.tic cance.(PC) oligome.astasis he.atic me.astasis pulmonary me.astasis surgical manage.e.t

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Journe. Through the.Groan Zone.with Acade.ics and Practitione.s: Bridging Conflict and Diffe.e.ce.to Stre.gthe. Disaste. Risk Re.uction and Re.ove.y Work

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Inte.national Journal of Disaste. Risk Scie.ce 2018年第3期9卷 421-428页

作者： katherine e.Browne.Cae.a O'Conne.l Laura Me.tzne. Yode. De.artme.t of Anthropology Colorado State University De.artme.t of Anthropology – Disaste.s Displacement and Human Rights Program University of Tennessee Program in Human Ne.ds and Global Re.ource. Wheaton College

Acade.ic-practitione. divide. in disaste. manage.e.t and re.e.rch can be.pe.siste.t and pe.nicious,be.ring conse.ue.ce. for disaste. survivors and future.affe.te. populations. The.gap be.we.n disaste. profe.sionals and acade.ic re.e.rche.s is ofte. tre.te. as an unavoidable.structural proble. or a ne.tral accide.t of profe.sional silos and circumstance. We.sugge.t that the.e.gaps are.not ne.tral, and that the. can and must be.ove.come. With hundre.s of millions of pe.ple.affe.te. by disaste. e.ch ye.r and re.ove.y costs skyrocke.ing, the.e.is urge.cy in conne.ting re.e.rche. and practitione. knowle.ge. to avoid e.pe.sive.mistake. and most importantly, to de.re.se.human suffe.ing. Ye. the.difficultie. that US acade.ic anthropologists and practitione.s e.pe.ie.ce. in the.r e.forts to collaborate.be.ame.e.ide.t in a cross-se.tor National Scie.ce.Foundation(NSF)-funde. workshop on the.re.e.ance.of culture.in disaste. work. We.sugge.t and illustrate.how more.syste.atic cross-fie.d communication can be.ope.ationalize. through e.gaging in an ongoing and re.ational proce.s of bridging. Such a proce.s can offe. long-te.m be.e.its to the.pe.ple.and institutions involve.,dramatically e.hance.the.scie.ce.of disaste. manage.e.t,and he.p re.uce.the.social and mate.ial costs of disaste. impacts.

关键词： Acade.ic and practitione. divide Applie. re.e.rch Cross-se.tor communication Culture and disaste. Disaste. anthropology Disaste. manage.e.t

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Re.ion-spe.ific microRNA signature. in the.human e.ididymis

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Asian Journal of Andrology 2018年第6期20卷 539-544页

作者： Jame. A Browne.Shih-Hsing Le.r Scott e.e.ge.e. Ann harris De.artme.t of Ge.e.ics and Ge.ome.Scie.ce. Case Western Reserve UniversityClevelandOH 44106USA Human Mole.ular Ge.e.ics Program Lurie Children＇s Research CenterChicagoIL 60614USA De.artme.t of Pe.iatrics Northwestern University Feinberg School of MedicineChicagoIL 60611USA Se.tion of Urology University of Chicago Medical CenterChicagoIL 60611USA.

The.e.ithe.ium of the.human e.ididymis maintains an appropriate.luminal e.vironme.t for spe.m maturation that is e.se.tial for male.fe.tility. Re.ional e.pre.sion of small noncoding RNAs such as microRNAs contribute. to se.me.t-spe.ific ge.e.e.pre.sion and diffe.e.tiate. functions. MicroRNA profile. we.e.re.orte. in human e.ididymal tissue. but not spe.ifically in the.e.ithe.ial ce.ls de.ive. from those.re.ions. He.e. we.re.e.l miRNA signature. of primary culture. of caput, corpus, and cauda e.ididymis e.ithe.ial ce.ls and of the.tissue. from which the. we.e.de.ive.. We.ide.tify 324 e.ithe.ial ce.l-de.ive. microRNAs and 259 tissue.de.ive. microRNAs in the.e.ididymis, some.of which displaye. re.ionalize. e.pre.sion patte.ns in ce.ls and/or tissue.. Caput ce.l-e.riche. miRNAs include. miR-573 and miR-155. Cauda ce.l-e.riche. miRNAs include. miR-1204 and miR-770. Ne.t, we.de.e.mine. the.ge.e.ontology pathways associate. with in silico pre.icte. targe. ge.e. of the.diffe.e.tially e.pre.se. miRNAs. The.e.fe.t of androge. re.e.tor stimulation on miRNA e.pre.sion was also inve.tigate.. The.e.data show nove. e.ithe.ial ce.l-de.ive. miRNAs that may re.ulate.the.e.pre.sion of important ge.e.ne.works that are.re.ponsible.for the.re.ionalize. ge.e.e.pre.sion and function of the.e.ididymis.

关键词： caput cauda corpus human e.ididymis microRNA

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Characte.ization of nove. Brown midrib 6 mutations affe.ting lignin biosynthe.is in sorghum

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Journal of Inte.rative.Plant Biology 2016年第2期58卷 136-149页

作者： e.in D. Scully Tammy Grie. De.nna L. Funne.l-harris Zhanguo Xin Frank A. Kovacs Wilfre. Ve.me.ris Scott e. Sattle. Grain Forage and Bioenergy Research Unit USDA-ARS Lincoln NE 68583 USA De.artme.t of Agronomy and Horticulture University of Nebraska-Lincoln Lincoln NE 68583 USA De.artme.t of Plant Pathology University of Nebraska-Lincoln Lincoln NE 68583 USA Plant Stre.s and Ge.mplasm De.e.opme.t Unit USDA-ARS Lubbock TX 79414 USA De.artme.t of Che.istry University of Nebraska-Kearney Kearney NE 68849 USA De.artme.t of Microbiology & Ce.l Scie.ce.and UF Ge.e.ics Institute University of Florida Gainesville FL 32610 USA

The.pre.e.ce.of lignin re.uce. the.quality of lignoce.lulosic biomass for forage.mate.ials and fe.dstock for biofue.s. In C4 grasse., the.brown midrib phe.otype.has be.n linke. to mutations to ge.e. in the.monolignol biosynthe.is pathway. For e.ample. the.Bmr6 ge.e.in sorghum （Sorghum bicolor） has be.n pre.iously shown to e.code.cinnamyl alcohol de.ydroge.ase.（CAD）, which catalyze. the.final ste. of the.monolignol biosynthe.is pathway. Mutations in this ge.e.have.be.n shown to re.uce.the.abundance.of lignin, e.hance.dige.tibility, and improve.saccharification e.ficie.cie. and e.hanol yie.ds. Nine.sorghum line. harboring five.diffe.e.t bmr6 alle.e. we.e.ide.tifie. in an e.S-mutage.ize. TILLING population. DNA se.ue.cing of Bmr6 re.e.le. that the.majority of the.mutations impacte. e.olutionarily conse.ve. amino acids while.thre.-dime.sional structural mode.ing pre.icte. that all of the.e.alle.e. inte.fe.e. with the.e.zyme.s ability to bind with its NAPPH cofactor. All of the.ne. alle.e. re.uce. in vitro CAD activity le.e.s and e.hance. glucose.yie.ds following saccharification. Furthe., many of the.e.line. we.e.associate. with highe. re.uctions in acid de.e.ge.t lignin compare. to line. harboring the.pre.iously characte.ize. bmr6-re. alle.e. The.e.bmr6 line. re.re.e.t ne. bre.ding tools for manipulating biomass composition to e.hance.forage.and fe.dstock quality.

关键词： Cinnamyl alcohol de.ydroge.ase.(CAD) e.S mutage.e.is biofue.s C4 grass forage

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Two-dime.sional d-πconjugate. me.al-organic frame.ork base. on he.ahydroxytrinaphthyle.e

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Nano Re.e.rch 2021年第2期14卷 369-375页

作者： Zhe.g Me.g katherine A.Mirica De.artme.t of Che.istry Burke Laboratory41 College Streety Dartmouth CollegeHanoverNH 03755USA

The.de.e.opme.t of ne. two-dime.sional(2D)d-πconjugate. me.al-organic frame.orks(MOFs)holds gre.t promise.for the.construction of a ne. ge.e.ation of porous and se.iconductive.*** pape. de.cribe. the.synthe.is,structural characte.ization,and e.e.tronic prope.tie. of a ne. d-πconjugate. 2D MOF base. on the.use.of a ne. ligand 2,3,8,9,14,*** re.icular se.f-asse.bly of this large.-conjugate. organic building block with Cu(II)ions in a mixe. solve.t syste. of 1,3-dime.hyl-2-imidazolidinone.DMI)and H2 O with the.addition of ammonia wate. or e.hyle.e.iamine.le.ds to a highly crystalline.MOF Cu3(HHTN)2,which posse.se. pore.ape.ture.of 2.5 ***3(HHTN)2 MOF shows mode.ate.e.e.trical conductivity of 9.01×10^(-8)S·cm^(-1)at 385 K and te.pe.ature.de.e.de.t band gap ranging from 0.75 to 1.65 *** che.ical oxidation by l2,the.conductivity of Cu3(HHTN)2 can be.incre.se. by 360 *** acce.s to HHTN base. MOF adds an important me.be. to pre.iously re.orte. MOF syste.s with he.agonal lattice.paving the.way towards syste.atic studie. of structure.prope.ty re.ationships of se.iconductive.MOFs.

关键词： two-dime.sional me.al-organic frame.ork(MOF) trinaphthyle.e conductive.MOF

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e.timating ance.tral distributions of line.ge. with unce.tain siste. groups:a statistical approach to Dispe.sal-Vicariance.Analysis and a case.using Ae.culus L.(Sapindace.e. including fossils

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Journal of Syste.atics and e.olution 2009年第5期47卷 349-368页

作者： A.J.harris North Carolina State.Unive.sity Department of Plant Biology

We.propose.a simple.statistical approach for using Dispe.sal-Vicariance.Analysis(DIVA) software.to infe. bioge.graphic historie. without fully bifurcating *** this approach,ance.tral range. are.first optimize. for a sample.of Baye.ian *** probability P of an ance.tral range.r at a node.is the. calculate. as P(rY) = n t=1 F(rY)t Pt whe.e.Y is a node.and F(rY) is the.fre.ue.cy of range.r among all the.optimal solutions re.ulting from DIVA optimization at node.Y,t is one.of n topologie. optimize.,and Pt is the.probability of topology *** Y is a hypothe.ize. ance.tor share. by a spe.ific crown line.ge.and the.siste. of that line.ge."x",whe.e.x may vary due.to phyloge.e.ic unce.tainty(polytomie. and node. with poste.ior probability e.hod,the.ance.tral distribution at Y can be.e.timate. to provide.infe.e.ce.of the.ge.graphic origins of the.spe.ific crown group of *** approach take. into account phyloge.e.ic unce.tainty as we.l as unce.tainty from DIVA *** is an e.te.sion of the.pre.iously de.cribe. me.hod calle. Baye.-DIVA,which pairs Baye.ian phyloge.e.ic analysis with bioge.graphic analysis using ***,we.show that the.probability P of an ance.tral range.at Y calculate. using this me.hod doe. not e.uate.to pp*F(rY) on the.Baye.ian conse.sus tre. whe. both variable. are.e.e.pp is the.poste.ior probability and F(rY) is the.fre.ue.cy of range.r for the.node.containing the.spe.ific crown *** te.te. our DIVA-Baye. approach using Ae.culus L.,which has major line.ge. unre.olve. as a *** infe.re. the.most probable.ge.graphic origins of the.five.traditional se.tions of Ae.culus and of Ae.culus californica *** e.amine. range.subdivisions at pare.tal node. of the.e.***,we.use. the.DIVA-Baye. data from Ae.culus to quantify the.e.fe.ts on bioge.graphic infe.e.ce.of including two wildcard fossil taxa in phyloge.e.ic *** analysis re.olve. the.ge.graphic range. of the.pare

关键词： Ae.culus bioge.graphy DIVA fossil wildcards MrBaye. phyloge.e.ic unce.tainty.

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Plasmon point spre.d functions： How do we.mode. plasmon-me.iate. e.ission proce.se.？

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Frontie.s of physics 2014年第1期9卷 3-16页

作者： katherine A. Wille.s De.artme.t of Che.istry University of Texas at AustinWelch Hall 1.202 105 E 2~TH ST. STOP A5300 Austin TX 78712 USA

A major challe.ge.with studying plasmon-me.iate. e.ission e.e.ts is the.small size.of plasmonic nanoparticle. re.ative.to the.wave.e.gth of light. Obje.ts smalle. than roughly half the.wave.e.gth of light will appe.r as diffraction-limite. spots in far-fie.d optical image., pre.e.ting a significant e.pe.ime.tal challe.ge.for studying plasmonic proce.se. on the.nanoscale. Supe.-re.olution imaging has re.e.tly be.n applie. to plasmonic nanosyste.s and allows plasmon-me.iate. e.ission to be.re.olve. on the.orde. of ~5 nm. In supe.-re.olution imaging, a diffraction-limite. spot is fit to some.mode. function in orde. to calculate.the.position of the.e.ission ce.troid, which re.re.e.ts the.loca- tion of the.e.itte.. Howe.e., the.accuracy of the.ce.troid position strongly de.e.ds on how we.l the.fitting function de.cribe. the.data. This Pe.spe.tive.discusse. the.commonly use. two-dime.sional Gaussian fitting function applie. to supe.-re.olution imaging of plasmon-me.iate. e.ission, the. introduce. an alte.native.mode. base. on dipole.point spre.d flmctions. The.two fitting mode.s are.compare. and contraste. for supe.-re.olution imaging of nanoparticle.scatte.ing/lumine.ce.ce. surface.e.hance. Raman scatte.ing, and surface.e.hance. fluore.ce.ce.

关键词： plasmon point spre.d function dipole supe.-re.olution surface.e.hance. Ramanscatte.ing (Se.S)

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Dual de.tructive.and prote.tive.role. of adaptive.immunity in ne.rode.e.e.ative.disorde.s

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Translational Ne.rode.e.e.ation 2014年第1期3卷 180-203,179页

作者： Kristi M Ande.son katherine e.Olson katherine A e.te. Ke. Flanagan Howard e.Ge.de.man R Le. Mosle. De.artme.t of Pharmacology and e.pe.ime.tal Ne.roscie.ce Center for Neurodegenerative DisordersThe University of Nebraska Medical CenterOmahaNE 68198USA Prothe.a Bioscie.ce. Inc.650 Gateway BoulevardSouth San FranciscoCA 94080USA

Inappropriate.T ce.l re.ponse. in the.ce.tral ne.vous syste.(CNS)affe.t the.pathoge.e.is of a broad range.of ne.roinflammatory and ne.rode.e.e.ative.disorde.s that include.but are.not limite. to,multiple.scle.osis,amyotrophic late.al scle.osis,Alzhe.me.’s dise.se.and Parkinson’s *** the.one.hand immune.re.ponse. can e.ace.bate.ne.rotoxic re.ponse.;while.on the.othe. hand,the. can le.d to ne.roprote.tive.*** te.poral and spatial me.hanisms by which the.e.immune.re.ponse. occur and are.re.ulate. in the.se.ting of active.dise.se.have.gaine. significant re.e.t ***,immune.re.ponse. that affe.t ne.rode.e.e.ation may occur within or outside.the.*** of antige.-spe.ific CD4+T ce.ls from the.pe.iphe.y to the.CNS and conse.ue.t immune.ce.l inte.actions with re.ide.t glial ce.ls affe.t ne.roinflammation and ne.ronal *** de.tructive.or prote.tive.me.hanisms of the.e.inte.actions are.linke. to the.re.ative.nume.ical and functional dominance.of e.fe.tor or re.ulatory T ***,immune.re.ponse. at dise.se.onse. or during progre.sion may e.hibit a diffe.e.tial balance.of immune.re.ponse. in the.pe.iphe.y and within the.*** re.ponse. with pre.ominate.T ce.l subtype. may diffe.e.tially manife.t migratory,re.ulatory and e.fe.tor functions whe. trigge.e. by e.doge.ous misfolde. and aggre.ate. prote.ns and ce.l-spe.ific *** final re.ult is alte.e. glial and ne.ronal be.aviors that influe.ce.the.dise.se.***,discove.y of ne.rode.tructive.and ne.roprote.tive.immune.me.hanisms will pe.mit pote.tial ne. the.ape.tic pathways that affe.t ne.ronal survival and slow dise.se.progre.sion.

关键词： Ne.rode.e.e.ation Ne.roprote.tion Migration MPTP MCAM Re.ulatory T ce.l e.fe.tor T ce.l,Ne.roinflammation

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De.p le.rning base. classification of she.p be.aviour from acce.e.ome.e. data with imbalance

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Information Proce.sing in Agriculture 2023年第3期10卷 377-390页

作者： Kirk e.Turne. Andre. Thompson Ian harris Mark Fe.guson Fe.dous Sohe. Discipline.of Information Te.hnology Murdoch UniversityMurdochWA 6150Australia Ce.tre.for Crop and Food Innovation Food Futures InstituteMurdoch UniversityMurdochWA 6150Australia Colle.e.of Scie.ce HealthEngineering and EducationMurdoch UniversityMurdochWA 6150Australia ne.tge. Agri Saint MartinsChristchurch 8022New Zealand

Classification of she.p be.aviour from a se.ue.ce.of tri-axial acce.e.ome.e. data has the.pote.tial to e.hance.she.p *** be.aviour is inhe.e.tly imbalance.(e.g.,more.ruminating than walking)re.ulting in unde.pe.forming classification for the.minority activitie. which hold *** works have.not addre.se. class imbalance.and use.traditional machine.le.rning te.hnique.,e.g.,Random Fore.t(RF).We.inve.tigate. De.p Le.rning(DL)mode.s,name.y,Long Short Te.m Me.ory(LSTM)and Bidire.tional LSTM(BLSTM),appropriate.for se.ue.tial data,from imbalance. *** data se.s we.e.colle.te. in normal grazing conditions using jaw-mounte. and e.rmounte. *** to this study,alongside.typical single.classe.,e.g.,walking,de.e.ding on the.be.aviours,data sample. we.e.labe.le. with compound classe.,e.g.,walking_-*** numbe. of ste.s a she.p pe.forme. in the.obse.ve. 10 s time.window was also re.orde. and incorporate. in the.*** de.igne. se.e.al multi-class classification studie. with imbalance.be.ng addre.se. using synthe.ic *** mode.s achie.e. supe.ior pe.formance.to traditional ML mode.s,e.pe.ially with augme.te. data(e.g.,4-Class+Ste.s:LSTM 88.0%,RF 82.5%).DL me.hods showe. supe.ior ge.e.alisability on unse.n she.p(i.e.,F1-score.BLSTM 0.84,LSTM 0.83,RF 0.65).LSTM,BLSTM and RF achie.e. sub-millise.ond ave.age.infe.e.ce.time.making the. suitable.for re.l-time.*** re.ults de.onstrate.the.e.fe.tive.e.s of DL mode.s for she.p be.aviour classification in grazing *** re.ults also de.onstrate.the.DL te.hnique. can ge.e.alise.across diffe.e.t *** study pre.e.ts a strong foundation of the.de.e.opme.t of such mode.s for re.l-time.animal monitoring.

关键词： She.p be.aviour classification Data synthe.is Class imbalance Grazing she.p

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