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Frontiers in Energy 2013年第4期7卷 495-505页

作者： Sunil DHINGRA Gian BHUSHAN kashyap kumar dubey University Institute of Engineering and Technology Kurukshetra University Kurukshetra 136119 India National Institute of Technology Kurukshetra 136119 India University Institute of Engineering and Technology Maharshi DayanandUniversity Rohtak 124001 India

This paper described the production of karanja biodiesel using response surface methodology （RSM） and genetic algorithm （GA）. The optimum combination of reaction variables were analyzed for maximizing the biodiesel yield. The yield obtained by the RSM was 65% whereas the predicted value was 70%. The mathematical regression model proposed from the RSM was coupled with the GA. By using this technique, 90% of the yield was obtained at a molar ratio of 38, a reaction time of 8 hours, a reaction temperature of 40 ℃, a catalyst concentration of 2% oil, and a mixing speed of 707 r/min. The yield produced was closer to the predicted value of 94.2093%. Hence, 25% of the improvement in the biodiesel yield was reported. Moreover the different properties of karanja biodiesel were found closer to the American Society for Testing ＆ Materials （ASTM） standard of biodiesel.

关键词： optimization of karanja biodiesel genetic algorithm (GA) response surface methodology (RSM) percentage improvement in the biodiesel yield properties of biodiesel

Multi-objective optimization of combustion, performance and emission parameters in a jatropha biodiesel engine using non-dominated sorting genetic algorithm-II

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Frontiers of Mechanical Engineering 2014年第1期9卷 81-94页

作者： Sunil Dhingra Gian Bhushan kashyap kumar dubey Department of Mechanical Engineering University Institute of Engi-neering and Technology Kurukshetra University Kttnakshetra Department of Mechanical Engineering National Institute of Technolo-gy Kurukshetra Department of Biotechnology University Institute of Engineering andTechnology Maharshi Dayanand University Rohtak

The present work studies and identifies the different variables that affect the output parameters involved in a single cylinder direct injection compression ignition （CI） engine using jatropha biodiesel. Response surface methodology based on Central composite design （CCD） is used to design the experiments. Mathematical models are developed for combustion parameters （Brake specific fuel consumption （BSFC） and peak cylinder pressure （Pmax））, performance parameter brake thermal efficiency （BTE） and emission parameters （CO, NOx, unburnt HC and smoke） using regression techniques. These regression equations are further utilized for simultaneous optimization of combustion （BSFC, Pmax）, performance （BTE） and emission （CO, NOx, HC, smoke） parameters. As the objective is to maximize BTE and minimize BSFC, Pmax, CO, NOx, HC, smoke, a multi- objective optimization problem is formulated. Non- dominated sorting genetic algorithm-II is used in predict- ing the Pareto optimal sets of solution. Experiments are performed at suitable optimal solutions for predicting the combustion, performance and emission parameters to check the adequacy of the proposed model. The Pareto optimal sets of solution can be used as guidelines for the end users to select optimal combination of engine outputand emission parameters depending upon their own requirements.

关键词： jatropha biodiesel fuel properties responsesurface methodology multi-objective optimization non-dominated sorting genetic algorithm-II

Engineering microalgae as the next-generation food

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Systems Microbiology and Biomanufacturing 2023年第1期3卷 166-178页

作者： Anshu Baldia Deepanshi Rajput Akshay kumar Ashok Pandey kashyap kumar dubey Bioprocess Engineering Laboratory School of BiotechnologyJawaharlal Nehru UniversityNew Delhi‑110067India Centre for Innovation and Translational Research CSIR-Indian Institute of Toxicology ResearchLucknow 226001India

Globally,microalgae are gaining attention due to their high nutritional value and broad application in the pharmaceutical,nutraceutical,food,cosmetics,bio-fertilizer,and biofuel ***-based foods have been shown a positive impact on human health by acting as antioxidants,antimicrobials,anti-inflammatory agents,and antiviral ***-up,production cost,and safety issues are the significant challenges in microalgae product ***,various techniques have been developed to overcome these challenges and to produce microalgae bio-products in a high amount and make them safe for human and animals ***,multiple techniques such as metabolic and genetic engineering have emerged to overcome these *** present review focused on the application of these engineering tools to improve biomass yield and nutrient quality in ***,these tools are proved to be very effective in enhancing the nutrients in *** success has been achieved to improve the quality at the industrial level.

关键词： Microalgae engineering Food industry Human health Sustainability

Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates

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Genes & Diseases 2024年第1期11卷 34-37页

作者： Budhadev Baral Dharmendra kashyap Nidhi Varshney Tarun Prakash Verma Ajay kumar Jain Debi Chatterji Vinod kumar Amit Mishra Awanish kumar Hem Chandra Jha Infection Bioengineering Group Department of Biosciences and Biomedical EngineeringIndian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Choithram Hospital and Research Center IndoreMadhya Pradesh452014India Department of Metallurgy Engineering and Materials Science Indian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Department of Bioscience&Bioengineering Indian Institute of Technology JodhpurNH 65 Nagaur RoadJodhpur DistrictKarwarRajasthan 342037India Department of Biotechnology National Institute of Technology RaipurGE RoadRaipurChhattisgarh 492010India

Persistent gastritis induced by Helicobacter pylori(***)is the strongest known risk factor for gastric cancer(GC).*** is prevalent in about 50%world's population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that *** infection can induce oncogenic properties in AGS cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression.

关键词： H.pylori pylori Helicobacter

Comprehensive analysis of uncertainty quantification for the^(58)Ni(n,p)^(58)Co reaction cross section

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Chinese Physics C 2024年第9期48卷 170-175页

作者： Mahesh Choudhary Aman Sharma Namrata Singh Mahima Upadhyay Punit dubey A.Gandhi Akash Hingu G Mishra Sukanya De L.S.Danu Ajay kumar R.G.Thomas Saurav Sood Sajin Prasad S.Mukherjee I.N.Ruskov Yu.N.Kopatch A.kumar Department of Physics Banaras Hindu UniversityVaranasi 221005India Horia Hulubei National Institute of Physics and Nuclear Engineering-IFIN-HH Bucharest 077125Romania Department of Physics The Maharaja Sayajirao University of BarodaVadodara 390002India Nuclear Physics Division Bhabha Atomic Research CentreMumbai 400085India Health Physics Division Bhabha Atomic Research CentreMumbai 400085India Department of Electrical Power Engineering Brno University of TechnologyBrno 61600Czech Republic Institute for Nuclear Research and Nuclear Energy Bulgarian Academy of SciencesSofia 1784Bulgaria Joint Institute for Nuclear Research(JINR) Dubna 141980Russia

In this study,we measured the^(58)Ni(n,p)^(58)Co reaction cross section with neutron energies of 1.06,1.86,and 2.85 *** cross section was measured using neutron activation techniques andγ-ray spectroscopy,and it was compared with cross section data available in the ***,we calculated the covariance matrix of the measured cross section for the aforementioned nuclear *** uncertainties of the theoretical calculation for^(58)Ni(n,p)^(58)Co reaction cross section were calculated via Monte Carlo *** this study,we used uncertainties in the optical model and level density parameters to calculate uncertainties in the theoretical cross *** theoretical calculations were performed by using *** this study,we aim to analyze the effect of uncertainties of the nuclear model input as well as different experimental variables used to obtain the values of reaction cross section.

关键词： ^(58)Ni(n p)^(58)Co reaction γ-ray spectroscopy uncertainty quantification of cross section covariance analysis

Fertilization and Soil Ploughing Practices under Changing Physical Environment Lead to Soil Organic Carbon Dynamics under Conservation Agriculture in Rice-Wheat Cropping System: A Scoping Review

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Agricultural Sciences 2024年第1期15卷 82-113页

作者： Salwinder Singh Dhaliwal Arvind kumar Shukla Sanjib kumar Behera Sarwan kumar dubey Agniva Mandal Mehakpreet Kaur Randhawa Sharanjit Kaur Brar Gagandeep Kaur Amardeep Singh Toor Sohan Singh Walia Priyadarshani Arun Khambalkar Department of Soil Science Punjab Agricultural University Ludhiana India Rajmata Vijayaraje Scindia Krishi Vishwa Vidyalaya Gwalior India Indian Institute of Soil Science (ISSS) Bhopal India Indian Council of Agricultural Research—Central Soil Salinity Research Institute (ICAR-CSSRI) Karnal India Department of Agricultural Chemistry and Soil Science Bidhan Chandra Krishi Viswavidyalaya Mohanpur India Department of Crop and Soil Sciences Washington State University Pullman USA School of Organic Farming Punjab Agricultural University Ludhiana India Department of Soil Science Rajmata Vijayaraje Sciendia Krishi Viswa Vidalaya Gwalior India

Ploughing and fertilization practices in rice-wheat system have deteriorated the soil carbon (C) pools. Conservation agriculture (CA) based management approaches have proven to enhance C sequestration and reverse the loss of soil-organic-carbon (SOC), which further enhances soil fertility. Different fractions of SOC pools react to the alterations in management practices and indicate changes in SOC dynamics as compared to total C in the soil. Higher SOC levels in soil have been observed in case of reduced/no-till (NT) practices than conventional tillage (CT). However, between CT and zero tillage/NT, total SOC stocks diminished with an increase in soil depth, which demonstrated that the benefits of SOC are more pronounced in the topsoil under NT. Soil aggregation provides physical protection to C associated with different-sized particles, thus, the improvement in soil aggregation through CA is an effective way to mitigate soil C loss. Along with less soil disturbance, residual management, suitable crop rotation, rational application of manures and fertilizers, and integrated nutrient management have been found to be effective in not only improving soil C stock but also enhancing the soil health and productivity. Thus, CA can be considered as a potential method in the build-up of SOC of soil in rice-wheat system.

关键词： Tillage Conservation Agriculture Soil Organic Carbon Carbon Fractions Rice-Wheat System Organic Amendments

Stability and Bifurcation of a Prey-Predator System with Additional Food and Two Discrete Delays

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Computer Modeling in Engineering & Sciences 2021年第2期126卷 505-547页

作者： Ankit kumar Balram dubey Department of Mathematics BITS PilaniPilani CampusPilani333031India

In this paper,the impact of additional food and two discrete delays on the dynamics of a prey-predator model is *** interaction between prey and predator is considered as Holling Type-II functional *** additional food is provided to the predator to reduce its dependency on the *** delay is the gestation delay in predator while the other delay is the delay in supplying the additional food to *** positivity,boundedness and persistence of the solutions of the system are studied to show the system as biologically *** existence of steady states,their local and global asymptotic behavior for the non-delayed system are *** is shown that(i)predator’s dependency factor on additional food induces a periodic solution in the system,and(ii)the two delays considered in the system are capable to change the status of the stability behavior of the *** existence of periodic solutions via Hopf-bifurcation is shown with respect to both the *** analysis shows that both delay parameters play an important role in governing the dynamics of the *** direction and stability of Hopf-bifurcation are also investigated through the normal form theory and the center manifold *** experiments are also conducted to validate the theoretical results.

关键词： predator delay system

Anticoagulant use before COVID-19 diagnosis prevent COVID-19 associated acute venous thromboembolism or not:A systematic review and meta-analysis

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World Journal of Methodology 2024年第3期14卷 141-162页

作者： Kinza Iqbal Akshat Banga Taha Bin Arif Sawai Singh Rathore Abhishek Bhurwal Syeda Kisa Batool Naqvi Muhammad Mehdi Pankaj kumar Mitali Madhu Salklan Ayman Iqbal Jawad Ahmed Nikhil Sharma Amos Lal Rahul kashyap Vikas Bansal Juan Pablo Domecq Department of Internal Medicine Dow Medical CollegeKarachi 74200Pakistan Department of Internal Medicine Sawai Man Singh Medical CollegeJaipur 302004India Department of Internal Medicine Dr.Sampurnanand Medical CollegeJodhpur 342003RajasthanIndia Department of Gastroenterology and Hepatology Rutgers Robert Wood Johnson School of MedicineNew BrunswickNJ 08901United States Department of Internal Medicine Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical SciencesRohtak 124001HaryanaIndia Department of Nephrology and Hypertension Mayo ClinicRochesterMN 55905United States Department of Medicine Division of Pulmonary and Critical Care MedicineMayo ClinicRochesterMN 55905United States Department of Research Wellspan HealthYorkPA 17403United States

BACKGROUND Coagulopathy and thromboembolic events are associated with poor outcomes in coronavirus disease 2019(COVID-19)*** is conflicting evidence on the effects of chronic anticoagulation on mortality and severity of COVID-19 *** To summarize the body of evidence on the effects of pre-hospital anticoagulation on outcomes in COVID-19 *** A Literature search was performed on LitCovid PubMed,WHO,and Scopus databases from inception(December 2019)till June 2023 for original studies reporting an association between prior use of anticoagulants and patient outcomes in adults with *** primary outcome was the risk of thromboembolic events in COVID-19 patients taking *** outcomes included COVID-19 disease severity,in terms of intensive care unit admission or invasive mechanical ventilation/intubation requirement in patients hospitalized with COVID-19 infection,and *** random effects models were used to calculate crude and adjusted odds ratios(aORs)with 95%confidence intervals(95%CIs).RESULTS Forty-six observational studies met our inclusion *** unadjusted analysis found no association between prior anticoagulation and thromboembolic event risk[n=43851,9 studies,odds ratio(OR)=0.67(0.22,2.07);P=0.49;I2=95%].The association between prior anticoagulation and disease severity was non-significant[n=186782;22 studies,OR=1.08(0.78,1.49);P=0.64;I2=89%].However,pre-hospital anticoagulation significantly increased all-cause mortality risk[n=207292;35 studies,OR=1.72(1.37,2.17);P<0.00001;I2=93%].Pooling adjusted estimates revealed a statistically non-significant association between pre-hospital anticoagulation and thromboembolic event risk[aOR=0.87(0.42,1.80);P=0.71],mortality[aOR=0.94(0.84,1.05);P=0.31],and disease severity[aOR=0.96(0.72,1.26);P=0.76].CONCLUSION Prehospital anticoagulation was not significantly associated with reduced risk of thromboembolic events,improved survival,and lower disease seve

关键词： Prior anticoagulation COVID-19 Prehospital anticoagulation Chronic anticoagulation Mortality Severity Thromboembolic events

Sulfamic acid as a green,reusable catalyst for stepwise,tandem&one-pot solvent-free synthesis of pyrazole derivatives

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Chinese Chemical Letters 2017年第7期28卷 1571-1576页

作者： Veera Swamy Konkala Pramod kumar dubey Department of Chemistry Jawaharlal Nehru Technological University HyderabadCollege of EngineeringKukatpally 500085India

Sulfamic acid（SA） is a bi-functional, cost-effective and reusable green catalyst for the synthesis of 4-（pyrazol-4-yl）methylenepyrazol-5（4H）-one derivatives by one-pot, three-component condensation of pyrazol-4-carbaxaldehydes, b-ketoesters and phenyl hydrazine（Route-I）. In addition to this method,another simple condensation of pyrazol-4-carbaxaldehydes with pyrazolone in the presence of SA under the solvent-free condition in good yield is reported. The merits of these protocols are mild conditions,non-aqueous workup, high yields, easy availability of the catalyst, no chromatographic separation and inexpensive solid acid catalyst. Furthermore, SA could be recycled and reused for five times without losing its catalytic activity.

关键词： Pyrazol-4-carbaxaldehydes Knoevenagel condensation Sulfamic acid Multicomponent reaction Physical grinding

A threshold voltage model of short-channel fully-depleted recessed-source/drain(Re-S/D) SOI MOSFETs with high-k dielectric

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Chinese Physics B 2015年第10期24卷 604-611页

作者： Gopi Krishna Saramekala Sarvesh dubey Pramod kumar Tiwari Department of Electronics and Communication Engineering National Institute of Technology Shri Ramswaroop Memorial University

In this paper, a surface potential based threshold voltage model of fully-depleted（FD） recessed-source/drain（Re-S/D）silicon-on-insulator（SOI） metal-oxide semiconductor field-effect transistor（MOSFET） is presented while considering the effects of high-k gate-dielectric material induced fringing-field. The two-dimensional（2D） Poisson＇s equation is solved in a channel region in order to obtain the surface potential under the assumption of the parabolic potential profile in the transverse direction of the channel with appropriate boundary conditions. The accuracy of the model is verified by comparing the model＇s results with the 2D simulation results from ATLAS over a wide range of channel lengths and other parameters,including the dielectric constant of gate-dielectric material.

关键词： recessed-source/drain (Re-S/D) high-k gate-material fringing field and SCEs