检索结果-南通市图书馆

Epidemiology and Clinical Features of Mycobacterium avium Complex Pulmonary disease in a Brazilian Amazon Cohort

Advances in Microbiology 2024年第6期14卷 287-302页

作者： Jose Tadeu Colares Monteiro Adriana Rodrigues Barretto Ruan Seguin Azevedo Quaresma Bianca Miranda Gouveia Ismari Perini Furlaneto Victória Menezes da Costa Yan Corrêa Rodrigues Layana Rufino Ribeiro Ricardo J. de Paula souza e Guimarães Alex Brito souza Ana Roberta Fusco da Costa Karla Valéria Batista Lima Joao de Barros Barreto University Hospital Federal University of Par Belm Brazil Center for Biological and Health Sciences Ph.D. Program in Parasitic Biology in the Amazon Region (PPGBPA) State University of Par (UEPA) Belm Brazil department of Medicine Centro Universitrio do Par CESUPA Belm Brazil Bacteriology and Mycology Section Evandro Chagas Institute (SABMI/IEC) Ministry of Health Ananindeua Brazil Geoprocessing Laboratory Evandro Chagas Institute/SVSA/MS Ananineua Brazil

The incidence of Mycobacterium avium complex pulmonary disease (MACPd) has been globally increasing. The present study aims to provide a comprehensive analysis of clinical characteristics and treatment response among patients in the Amazon region of Brazil and conduct a retrospective cohort study at a prominent referral hospital in the State of Par, Brazil, from 2012 to 2020. The M. avium group represented 58.9% of cases, followed by M. intracellulare (35.7%), M. colombiense (3.6%), and M. chimaera (1.8%). The majority of patients (73.2%) were female and with an average age of 63 years. Primary clinical manifestations included persistent cough and sputum production. The Charlson comorbidity index (CCI) averaged 2.47, with 36.3% of patients having a CCI score equal to higher than 3. Notably, over 70% of patients had received treatment for pulmonary tuberculosis before initiating treatment for MAC infection. The fibrocavitary radiologic form was the most prevalent (55.4%), frequently exhibiting a bilateral distribution (53.6%). Antimicrobial susceptibility revealed a significant prevalence of MAC resistance to drugs in the therapeutic regimen. despite this, most of the patients experienced clinical improvement (50%). In conclusion, this study highlights a higher prevalence of MAC infections among middle-aged women, with a history of pulmonary tuberculosis treatment and presenting the fibrocavitary radiological form was predominant.

关键词： MACdP Nontuberculous Mycobacteria Mycobacterium avium Lung disease

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Influence of Sugarcane Bagasse Fiber Size on Biodegradable Composites of Thermoplastic Starch

引用

Journal of Renewable Materials 2018年第2期6卷 176-182页

作者： Bruno Henrique dos Santos karen de souza do Prado Asaph Armando Jacinto Marcia Aparecida da Silva Spinace Federal University of ABC Center of Natural and Human SciencesAv.dos Estados5001Santa Terezinha09.210-170 Santo AndréSão PauloBrazil

Although thermoplastic starch(TPS)is biodegradable,its low mechanical resistance limits its wide *** bagasse(SB)fibers can be used as reinforcement in TPS matrix composites,but the influence of fiber size on the properties of the composite is still *** this study,TPS composites reinforced with SB short fibers of four sizes were processed and characterized in order to analyze the influence of fiber size on the mechanical properties of the TPS/SB *** was observed that the interaction between fiber and matrix was good and optimized when the fibers are sifted in sieves between 30 and 50 mesh,obtaining fibers with average length of 1569±640μm and average diameter of 646±166μ*** these composites,increases of more than 660%in the modulus and more than 100%in the maximum tension were verified when compared to the pure TPS.

关键词： Sugarcane bagasse thermoplastic starch composite fiber size

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Results of selective decontamination with oral neomycin and metronidazole for major colorectal surgery in Australia:A cohort study

引用

Laparoscopic, Endoscopic and Robotic Surgery 2024年第2期7卷 72-78页

作者： James Wei Tatt Toh devansh Shah Henry Wang Charlotte Kwik Joseph do Woong Choi Chelsie Leonie Beinke Paul Morris Eleni Baird-Gunning Geoffrey Peter Collins Fiona Gavegan karen Shedden Toufic El-Khoury Nimalan Pathma-Nathan Kerry Hitos department of Colorectal Surgery Westmead HospitalWestmeadNew South WalesAustralia The University of Sydney Westmead HospitalWestmeadNew South WalesAustralia Western Sydney University New South WalesAustralia University of Notre dame New South WalesAustralia Westmead Research Centre for Evaluation of Surgical Outcomes Westmead HospitalSydneyAustralia

Objective The role of selective decontamination with oral antibiotics(OABs)and mechanical bowel preparation(MBP)prior to elective colorectal surgery is still widely *** objective of this study was to compare the outcomes of selective decontamination with neomycin,metronidazole and MBP compared to those of decontamination with MBP alone or with no *** Selective decontamination with neomycin and metronidazole combined with bowel preparation was introduced prior to elective colorectal surgery as part of an enhanced recovery after surgery program at Westmead Hospital,a major Australian tertiary referral hospital,between June 2017 and January *** between short-term outcomes of OAB+MBP and MBP/no preparation were made using prospectively collected data on length of stay(LOS),readmission,mortality within 30 days,anastomotic leakage(AL),surgical site infection(SSI),urinary tract infection,deep venous thrombosis and/or pulmonary embolism,pneumonia,and ***-up was limited to hospital stays and subsequent presentations within the health district within thirty days of *** Mann-Whitney U test was used to analyse continuous data,and the chi-square test was used for categorical *** and multivariate regression modelling was performed to identify risk factors associated with an increased likelihood of SSI and *** Patients with oral neomycin and metronidazole combined with bowel preparation had reduced superficial SSI(2.7%vs.7.6%,p=0.043)and overall complications(32.7%vs.44.6%,p=0.020),particularly Clavien-dindo 1 complications(7.3%vs.16.5%,p=0.009).However,the differences in AL(2.7%vs.4.5%,p=0.369)and organ/space SSI(1.3%vs.3.7%,p=0.327)were not statistically *** median LOS(6 d vs.6 d,p=0.370)was not different between the *** Selective decontamination with neomycin and metronidazole reduces the risk of SSIs and overall *** was a trend to toward a lower AL,but this differ

关键词： Neomycin Metronidazole Colorectal surgery Anastomotic leakage Surgical site infection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sentence,Phrase,and Triple Annotations to Build a Knowledge Graph of Natural Language Processing Contributions—A Trial dataset

引用

Journal of data and Information Science 2021年第3期6卷 6-34页

作者： Jennifer d.souza Sören Auer TIB Leibniz Information Centre for Science and Technology HannoverGermany

Purpose:This work aims to normalize the NLPCONTRIBUTIONS scheme(henceforward,NLPCONTRIBUTIONGRAPH)to structure,directly from article sentences,the contributions information in Natural Language Processing(NLP)scholarly articles via a two-stage annotation methodology:1)pilot stage-to define the scheme(described in prior work);and 2)adjudication stage-to normalize the graphing model(the focus of this paper).design/methodology/approach:We re-annotate,a second time,the contributions-pertinent information across 50 prior-annotated NLP scholarly articles in terms of a data pipeline comprising:contribution-centered sentences,phrases,and triple *** this end,specifically,care was taken in the adjudication annotation stage to reduce annotation noise while formulating the guidelines for our proposed novel NLP contributions structuring and graphing ***:The application of NLPCONTRIBUTIONGRAPH on the 50 articles resulted finally in a dataset of 900 contribution-focused sentences,4,702 contribution-information-centered phrases,and 2,980 surface-structured *** intra-annotation agreement between the first and second stages,in terms of F1-score,was 67.92%for sentences,41.82%for phrases,and 22.31%for triple statements indicating that with increased granularity of the information,the annotation decision variance is *** limitations:NLPCONTRIBUTIONGRAPH has limited scope for structuring scholarly contributions compared with STEM(Science,Technology,Engineering,and Medicine)scholarly knowledge at ***,the annotation scheme in this work is designed by only an intra-annotator consensus-a single annotator first annotated the data to propose the initial scheme,following which,the same annotator reannotated the data to normalize the annotations in an adjudication ***,the expected goal of this work is to achieve a standardized retrospective model of capturing NLP contributions from scholarly *** would entail a larger initiati

关键词： Scholarly knowledge graphs Open science graphs Knowledge representation Natural language processing Semantic publishing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Experimental and computational validation of a scaled train tunnel model using modal analysis

引用

Frontiers of Mechanical Engineering 2013年第4期8卷 420-428页

作者： Janice B.d.souza Sangarapillai KANAPATHIPILLAI School of Mechanical and Manufacturing Engineering The University of New South Wales

Acoustic engineers are faced with the challenge of minimising reverberation time in their designs so as to contribute to the health and well-being of those traveling by train and those on the *** the problem is easy to identify,it is not as simple to *** acoustical environment of a train tunnel is complex,with a variety of noise contributing factors such as train announcements,speech of commuters,ventilation systems,electrical equipment and wheel and rail *** a result,there is some difficulty in modeling the complete acoustic environment with computational or acoustic first *** this study,an experimental rig was constructed to model the acoustic behavior within a *** modal properties for the 300 Hz to 1500 Hz range,including resonances and mode shapes were identified and were shown to successfully correspond to theoretical results and a computational model created in COMSOL using Finite Element Analysis.

关键词： reverberation time acoustic environment modal properties resonances

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Breccia-cored columnar rosettes in a rubbly pahoehoe lava flow,Elephanta Island,deccan Traps,and a model for their origin

引用

地学前缘：英文版 2017年第6期8卷 1299-1309页

作者： Hetu Sheth Ishita Pal Vanit Patel Hrishikesh Samant Joseph d.souza department of Earth Sciences Indian Institute of Technology Bombay(IITB) Institute of Geophysics and Planetary Physics Scripps Institution of OceanographyUniversity of California San Diego department of Geology St.Xavier's College

Rubbly pahoehoe lava flows are abundant in many continental flood basalts including the deccan ***,structures with radial joint columns surrounding cores of flow-top breccia(FTB),reported from some deccan rubbly pahoehoe flows,are yet unknown from other basaltic provinces.A previous study of these deccan "breccia-cored columnar rosettes" ruled out explanations such as volcanic vents and lava tubes,and showed that the radial joint columns had grown outwards from cold FTB inclusions incorporated into the hot molten *** the highly vesicular(thus low-density)FTB blocks might have sunk into the flow interiors has remained a *** we describe a new example of a deccan rubbly pahoehoe flow with FTB-cored rosettes,from Elephanta Island in the Mumbai *** that(1)thick rubbly pahoehoe flows probably form by rapid inflation(involving many lava injections into a largely molten advancing flow),and(2)such flows are transitional to 'a'a flows(which continuously shed their top clinker in front of them as they advance),we propose a model for the FTB-cored *** suggest that the deccan flows under study were shedding some of their FTB in front of them as they advanced and,with high-eruption rate lava injection and inflation,frontal breakouts would incorporate this FTB rubble,with thickening of the flow carrying the rubble into the flow *** implies that,far from sinking into the molten interior,the FTB blocks may have been rising,until lava supply and inflation stopped,the flow began solidifying,and joint columns developed outward from each cold FTB inclusion as already inferred,forming the FTB-cored *** rubbly pahoehoe flows which began recycling most of their FTB became the 'a'a flows of the deccan.

关键词： Rubbly pahoehoe Columnar jointing Flow-top breccia Volcanism Flood basalt deccan Traps

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bacterial extracellular vesicle applications in cancer immunotherapy

引用

Bioactive Materials 2023年第4期22卷 551-566页

作者： Kanika Suri Anisha d.souza di Huang Aashray Bhavsar Mansoor Amiji department of Bioengineering College of EngineeringNortheastern UniversityBostonMA02115USA department of Pharmaceutical Sciences School of PharmacyNortheastern UniversityBostonMA02115USA Massachusetts Eye and Ear Infirmary Harvard Medical SchoolBostonMA20115USA department of Chemical Engineering College of EngineeringNortheastern UniversityBostonMA02115USA

Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various approaches to activate the host immune *** research to identify appropriate immune cells and activate anti-tumor immunity continues to expand,scientists are looking at microbial sources given their inherent ability to elicit an immune *** extracellular vesicles(BEVs)are actively studied to control systemic humoral and cellular immune responses instead of using whole microorganisms or other types of extracellular vesicles(EVs).BEVs also provide the opportunity as versatile drug delivery *** mammalian EVs,BEVs have already made it to the clinic with the meningococcal vaccine(Bexsero®).However,there are still many unanswered questions in the use of BEVs,especially for chronic systemically administered *** this review,we address the opportunities and challenges in the use of BEVs for cancer immunotherapy and provide an outlook towards development of BEV products that can ultimately translate to the clinic.

关键词： Cancer immunotherapy Bacterial extracellular vesicles Membrane vesicles Outer membrane vesicles Mammalian extracellular vesicles

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A novel ZnO/reduced graphene oxide and Prussian blue modified carbon paste electrode for the sensitive determination of Rutin

引用

Science China Chemistry 2019年第2期62卷 262-270页

作者： Ozma J d.souza Ronald J Mascarenhas Ashis K Satpati Basavanakote M Basavaraja Research and development Centre Bharathiar University Electrochemistry Research Group Department of Chemistry St.Joseph's College Analytical Chemistry division Bhabha Atomic Research Centre Anushakthi Nagar Trombay department of Chemistry PES University

A carbon paste modified sensor based on a novel composite of zinc oxide nanoparticles deposited on reduced graphene oxide(ZnO-rGrO) and Prussian blue(PB) was drop-cast(ZnO-rGrO-PB/MCPE) for the sensitive estimation of Rutin(Rtn) at pH *** high surface area of ZnO-rGrO and electrocatalytic property of PB promotes the oxidation of Rtn. Field emission scanning electron microscope(FE-SEM) and energy-dispersive X-ray spectroscopy(EdX) techniques were employed to confirm the deposition of ZnO-rGrO and PB on carbon paste electrode(CPE). The ability of ZnO-rGrO-PB/MCPE in charge transfer at the interface was investigated using electrochemical impedance spectroscopy(EIS). The heterogeneous rate constant(ks) and the charge transfer coefficient(α) have been calculated as 6.08 s^(-1) and 0.74 respectively. This sensor showed a wide linear response for Rtn from 7.0×10^(-8)to 7.0×10^(-6) M and 7.0×10^(-6) to 1.0×10^(-4) M with a limit of detection(2.05±0.04)×10^(-8) M(S/N=3). The application of ZnO-rGrO-PB/MCPE was found in the analysis of Rtn in fruit juice samples using standard addition method. This sensor showed good reproducibility, stability, selectivity and sensitivity.

关键词： Rutin zinc oxide nanoparticles reduced graphene oxide Prussian blue modified carbon paste electrode ascorbic acid

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Concerns about the application of resistance exercise with blood-flow restriction and thrombosis risk in hemodialysis patients

引用

Journal of Sport and Health Science 2024年第4期13卷 548-558,F0003页

作者： Hugo de Luca Correa Lysleine Alves deus dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araujo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinesio Silva Neto Claudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-Silva Fernando Honorato souza Vitoria Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos Rosangela Vieira Andrade Jonato Prestes Thiago dos Santos Rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home dialysis Center and RenalClass Sao Paulo 01239-040Brazil department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Background:Hemodialysis(Hd) per se is a risk factor for *** the growing body of evidence on blood-flow restriction(BFR) exercise in Hd patients,identification of possible risk factors related to the prothrombotic agent d-dimer is required for the safety and feasibility of this training *** aim of the present study was to identify risk factors associated with higher d-dimer levels and to determine the acute effect of resistance exercise(RE) with BFR on this ***:Two hundred and six Hd patients volunteered for this study(all with a glomerular filtration rate of d of 50% arterial occlusion pressure during 50 min sessions of Hd(intradialytic exercise).RE repetitions included concentric and eccentric lifting phases(each lasting 2 s) and were supervised by a strength and conditioning ***:Several variables were associated with elevated levels of d-dimer,including higher blood glucose,citrate use,recent cardiovascular events,recent intercurrents,higher inflammatory status,catheter as vascular access,older patients(>70 years old),and Hd ***,RE+BFR significantly increases d-dimer after 4 *** with borderline baseline d-dimer levels(400-490 ng/mL) displayed increased risk of elevating d-dimer over the normal range(≥500 ng/mL).Conclusion:These results identified factors associated with a heightened prothrombotic state and may assist in the screening process for Hd patients who wish to undergo RE+BFR.d-dimer and/or other fibrinolysis factors should be assessed at baseline and throughout the protocol as a precautionary measure to maximize safety during RE+BFR.

关键词： Blood-flow restriction Chronic kidney disease Coagulation Hemodialysis Vascular occlusion exercises

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Properties of Charmonium States in a Phenomenological Approach

引用

Communications in Theoretical Physics 2019年第2期71卷 192-202页

作者： Praveen P d.souza Antony Prakash Monteiro K.B.Vijaya Kumar department of Physics St Philomena College department of Physics Mangalore University

We investigate the spectrum and decay rates of charmonium states within the framework of the non relativistic quark model by employing a Coulomb like potential from the perturbative one gluon exchange and the linear confining potential along with the potential derived from instanton vacuum to account for the hyperfine mass splitting of charmonium states in variational approach. We predict radiative E1, M1, two-photon, lepton and two-gluon decay rates of low lying charmonium states. An overall agreement is obtained with the experimental masses and decay *** have estimated the branching ratio of two gluons decaying into light hadrons.

关键词： non-relativistic quark model instantons charmonium radiative decay two gluon decay two photon decay leptonic decay branching ratio

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：