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Undergraduate nursing students' knowledge of aging, attitudes toward and perceptions of working with older adults in Kathmandu Nepal

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International Journal of Nursing Sciences 2019年第2期6卷 204-210页

作者： Saruna Ghimire Nitisha Shrestha karen e.callahan Dhirendra Nath Binaya Kumar Baral Nirmala Lekhak Devendra Raj Singh Agrata Health and education(AHeAD)-Nepal KathmanduNepal School of Public Health University of NevadaLas VegasUSA Asian College for Advanced Studies Purbanchal UniversityLalitpurNepal Southeast Asia Development Actions Network(SADAN) LalitpurNepal Department of Biochemistry Nepal Medical College and Teaching HospitalKathmanduNepal School of Nursing University of NevadaLas VegasUSA

Objectives: This study aims to examine Nepalese undergraduate nursing students' knowledge of aging,attitudes towards older adults and perceptions of working with older adults,and to assess differences in these outcomes by socio-demographic characteristics as well as type of nursing ***: A cross-sectional study was conducted among 385 undergraduate nursing students in six nursing colleges located in the Kathmandu Valley,Knowledge of aging,attitudes toward older adults and perceptions of working with older adults were assessed using standardized tools,the Palmore Facts on Aging Quiz,Kogan's Attitudes towards Older People Scale,and Nolan's Intent to Work with Older People Questionnaire,***: The mean knowledge scores on older adults and aging were relatively low;participants scored an average of 26.9 out of *** assessing attitudes towards and perceptions of working with older adults were more *** to students pursuing a Bachelor of Science in Nursing (BSN),students pursuing a Bachelor of Nursing (BN) had a significantly higher score on the knowledge,attitudes and perception of aging *** regression analyses showed that the students' knowledge of aging (β =0.55;95% CI =0.25-0.86) and perceptions of working with older adults (β =0.22;95% Cl =0.05 -0.38) had a significant positive association with their attitudes toward older ***: Undergraduate nursing students in the Kathmandu Valley of Nepal displayed a relatively low level of knowledge,but a positive attitude towards older adults,and a positive perception of working with older *** differences in knowledge,attitude,and perception scores between students in BSN and BN programs needs further investigation;closing this gap may be important for bolstering undergraduate gerontological preparation in Nepal.

关键词： Aged Attitudes Knowledge Perceptions Students Nursing Nepal

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Prospective cohort study on facial profile changes in infants with Robin sequence and healthy controls

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World Journal of Pediatrics 2024年第6期20卷 581-589页

作者： Cornelia Wiechers Julian Sowula karen Kreutzer Christoph e.Schwarz Christina Weismann Michael Krimmel Christian F.Poets Bernd Koos Department of Neonatology Tuebingen University HospitalCalwerstrasse 772076 TuebingenGermany Center for Cleft Lip Palate and Craniofacial MalformationsTuebingen University HospitalTuebingenGermany Department of Orthodontics Tuebingen University HospitalTuebingenGermany Department of Oral and Maxillofacial Surgery Tuebingen University HospitalTuebingenGermany

Background Various conservative and surgical approaches exist to treat Robin sequence(RS),but their effects on facial profile and mandibular catch-up growth are unclear.A functional treatment concept,used in our centre for 25 years,includes an individualized palatal plate with a velo-pharyngeal extension and intensive feeding *** We performed a prospective study to objectively describe facial profiles in infants with RS treated with the above *** with isolated RS were admitted to our tertiary perinatal and national referral centre for craniofacial malformations between May 2018 and Nov *** with RS received 3D-photographs during clinically indicated *** controls were recruited from Dec 2018 to Sep 2019 and received 3D-photographs every 3 *** digitally measured jaw index(JI),defined as alveolar overjet(O)x maxillary arch(U)/mandibular arch(L),and the soft tissue reference points A’-point,Nasion’,B’-point angle(ANB’),describing the relative position of maxilla to mandible,were *** mixed models were used to examine time trajectories in JI and ANB’.Results A total of 2073D images,obtained in 19 infants with RS and 32 controls,were *** and ANB’decreased over time in both groups[for JI−0.18(95%CI−0.25 to−0.10);for ANB’:−0.40°per month[(95%CI−0.48 to−0.32)]]but remained lower in controls[for JI−2.5(95%CI−3.2 to−1.8);for ANB’-1.7°(95%CI−2.4 to−1.0)].Also,the ANB’model showed a significant effect of the interaction term diagnosis x *** Based on longitudinal 3D images,we describe changes in objective parameters of facial profile in infants with and without RS during the first year of *** findings indicate catch-up growth in infants treated for RS.

关键词： Infant Mandibular catch-up growth Pre-epiglottic Baton Plate Robin sequence Three-dimensional photography

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Confirmation of a Sub-Saturn-size Transiting exoplanet Orbiting a G Dwarf:TOI-1194 b and a Very Low Mass Companion Star: TOI-1251 B from TeSS

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Research in Astronomy and Astrophysics 2024年第3期24卷 129-143页

作者： Jia-Qi Wang Xiao-Jun Jiang Jie Zheng Hanna Kellermann Arno Riffeser Liang Wang karen A.Collins Allyson Bieryla Lars A.Buchhave Steve B.Howell elise Furlan eric Girardin Joao Gregorio eric Jensen Felipe Murgas Mesut Yilmaz Sam Quinn Xing Gao Ruo-Yu Zhou Frank Grupp Hui-Juan Wang CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy Of SciencesBeijing 10010China University of Chinese Academy of Sciences Beijing 100049China University Observatory Munich Scheinertrsse 1.D-81679 MunichGemany Max Planck Institute for extraterrestrial Physics Giessenbachstr.1D-85748 GarchingGermany National Astronomical Observatories/Nanjing Institute of Astronomical Optics&Technology Chinese Academy of SciencesNanjing210042China CAS Key Laboratory of Astronomical Optics&Technology Nanjing Institute of Astronomical Optics&TechnologyNanjing 210042China Center for Astrophysics Harvard&Smithsonian60 Garden Street.CambridgeMA 02138USA National Space Institute Technical University of DenmarkElektrovejDK-2800 KgsLyngbyDenmark NASA Ames Research Center Moffett FieldCA 94035USA NASA exoplanet Science Institute Caltech/IPACMail Code 100-221200 E.California Blvd.PasadenaCA91125USA Grand Pra Observatory Switzerland Department of Physics Washington UniversitySt.LouisMO 63130.USA Department of Physics and Astronomy Swarthmore CollegeSwarthmorePA 19081USA Instituto de Astrofísica de Canarias(IAC) E-38205 La Laguna.TenerifeSpain Departamento de Astrofísica Universidad de La LagunaSpain Dept.of Astronomy and Space Sciences Ankara UniversityTandogan 06100AnkaraTurkey Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Urumqi No.1 Senior High School Urumqi 830002China Lijiang Gemini Observatory Lijiang 674199China

We report the confirmation of a sub-Saturn-size exoplanet,TOI-1194 b,with a mass of about 0.456+0.055-0.051M_(J),and a very low mass companion star with a mass of about 96.5±1.5 MJ,TOI-1251 *** candidates provided by the Transiting exoplanet Survey Satellite(TeSS)are suitable for further follow-up observations by ground-based telescopes with small and medium *** analysis is performed based on data from several telescopes worldwide,including telescopes in the Sino-German multiband photometric campaign,which aimed at confirming TeSS Objects of Interest(TOIs)using ground-based small-aperture and medium-aperture telescopes,especially for long-period ***-1194 b is confirmed based on the consistent periodic transit depths from the multiband photometric *** measure an orbital period of 2.310644±0.000001 days,the radius is 0.767+0.045-0.041RJ and the amplitude of the RV curve is 69.4_(-7.3)^(+7.9)m s^(-1).TOI-1251 B is confirmed based on the multiband photometric and high-resolution spectroscopic data,whose orbital period is 5.963054+0.000002-0.000001days,radius is 0.947+0.035-0.033 R_(J) and amplitude of the RV curve is 9849_(-40)^(+42)ms^(-1).

关键词： planets and satellites fundamental parameters-planets and satellites gaseous planets-stars fundamental parameters-stars low-mass-methods data analysis-techniques photometric-techniques spectroscopic

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Outcomes and management of viral hepatitis and human immunodeficiency virus co-infection in liver transplantation

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World Journal of Gastroenterology 2014年第2期20卷 414-424页

作者： Stephen e Congly karen e Doucette Carla S Coffin Liver Unit Division of Gastroenterology and HepatologyUniversity of CalgaryCalgaryAB T2N 4Z6Canada Division of Infectious Diseases University of AlbertaEdmontonAB T6G 2R3Canada

Liver transplantation for human immunodeficiency virus(HIV)positive patients with viral hepatitis co-infection is increasingly offered in many North American and european liver transplant *** studies have demonstrated acceptable post-transplant outcomes and no increased risk of HIV complications in patients coinfected with hepatitis B virus(HBV).However,liver transplantation in HIV positive patients with hepatitis C virus(HCV)has poorer outcomes overall,requiring careful selection of *** review aims to summarize the published literature on outcomes after transplant in HIV patients with HBV or HCV related end-stage liver disease and recommendations for *** particular the pre-transplant factors impacting outcomes in HCV/HIV co-infected candidates and importance of multidisciplinary management will be discussed.

关键词： Hepatitis B virus Human immunodeficiency virus co-infection Hepatitis C virus Co-infection Liver transplantation

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Identification of a novel population of human cord blood cells with hema-topoietic and chondrocytic potential

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Cell Research 2004年第4期14卷 268-282页

作者： karen e JAY,Anne ROULeAU,T Michael UNDeRHILL,Mickie BHATIA Stem Cell Biology and Regenerative Medicine The John P. Robarts Research Institute 100 Perth Drive London Ontario N6A 5K8 Canada Department of Microbiology and Immunology The University of Western Ontario London Ontario Canada Stem Cell Biology and Regenerative Medicine The John P. Robarts Research Institute 100 Perth Drive London Ontario N6A 5K8 Canada Department of Physiology The University of Western Ontario London Ontario Canada Stem Cell Biology and Regenerative Medicine The John P. Robarts Research Institute 100 Perth Drive London Ontario N6A 5K8 Canada Department of Microbiology and Immunology The University of Western Ontario London Ontario Canada. Department of Physiology The University of Western Ontario London Ontario Canada

With the exception of mature erythrocytes, cells within the human hematopoietic system are characterized by the cell surface expression of the pan-leukocyte receptor CD45. Here, we identify a novel subset among mononuclear cord blood cells depleted of lineage commitment markers (Lin) that are devoid of CD45 expression. Surprisingly, functional examination of Lin"CD45" cells also lacking cell surface CD34 revealed they were capable of multipotential hematopoietic progenitor capacity. Co-culture with mouse embryonic limb bud cells demonstrated that Lin-CD45-CD34- cells were capable of contributing to cartilage nodules and differentiating into human chondrocytes. BMP-4, a mesodermal factor known to promote chondrogenesis, significantly augmented Lin-CD45-CD34- differentiation into chondrocytes. Moreover, unlike CD34+ human hematopoietic stem cells, Lin-CD45-CD34- cells were unable to proliferate or survive in liquid cultures, whereas single Lin-CD45-CD34- cells were able to chimerize the inner cell mass (IC

关键词： hematopoietic chondrocyte CD45 embryonic.

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Planning for Community Relocations Due to Climate Change in Fiji

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International Journal of Disaster Risk Science 2015年第3期6卷 315-319页

作者： karen e.Mc Namara Helene Jacot Des Combes School of Geography Planning and Environmental ManagementThe University of Queensland Pacific Centre for environment and Sustainable Development University of the South Pacific

As a consequence of the impacts of climate change, some households and entire communities across the Pacific are making the complex and challenging decision to leave their homelands and relocate to new environments that can sustain their livelihoods. This short article charts how the residents of Vunidogoloa village in Fiji relocated in early 2014 to reduce their vulnerability to encroaching sea level and inundation events that regularly devastated the community. As a consequence of the Vunidogoloa relocation, this article also explores how the Fiji Government is planning for similar resettlement transitions, including vulnerability and adaptation assessments to develop a list of potential community relocations and the development of national relocation guidelines. This study draws from key informant interviews(n = 8) with government officials, as well as representatives from intergovernmental and local nongovernmental organizations,who are involved in the relocation issue. Given the speed at which these national, top-down initiatives are being forged and especially in light of the absence of any mention of relocation in Fiji’s 2012 climate change policy, careful and inclusive engagement across all scales and stakeholders,including communities 'earmarked' for relocation, is paramount.

关键词： Climate change Community relocation Fiji Risk planning Sea level rise

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Colon adenoma features and their impact on risk of future advanced adenomas and colorectal cancer

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World Journal of Gastrointestinal Oncology 2016年第12期8卷 826-834页

作者： Audrey H Calderwood karen e Lasser Hemant K Roy Section of Gastroenterology Depart-ment of MedicineDartmouth-Hitchcock Medical Center Section of General Internal Medicine Depart-ment of MedicineBoston University School of Medicine Section of Gastroenterology Department of MedicineBoston University School of Medicine

AIMTo review the evidence on the association between specific colon adenoma features and the risk of future colonic neoplasia [adenomas and colorectal cancer (CRC)]. MeTHODSWe performed a literature search using the National Library of Medicine through PubMed from 1/1/2003 to 5/30/2015. Specific Medical Subject Headings terms (colon, colon polyps, adenomatous polyps, epidemiology, natural history, growth, cancer screening, colonoscopy, CRC) were used in conjunction with subject headings/key words (surveillance, adenoma surveillance, polypectomy surveillance, and serrated adenoma). We defined non-advanced adenomas as 1-2 adenomas each 25% villous histology or high-grade dysplasia. A combined endpoint of advanced neoplasia included advanced adenomas and invasive CRC. ReSULTSOur search strategy identified 592 candidate articles of which 8 met inclusion criteria and were relevant for assessment of histology (low grade vs high grade dysplasia, villous features) and adenoma size. Six of these studies met the accepted quality indicator threshold for overall adenoma detection rate > 25% among study patients. We found 254 articles of which 7 met inclusion criteria for the evaluation of multiple adenomas. Lastly, our search revealed 222 candidate articles of which 6 met inclusion criteria for evaluation of serrated polyps. Our review found that villous features, high grade dysplasia, larger adenoma size, and having ≥ 3 adenomas at baseline are associated with an increased risk of future colonic neoplasia in some but not all studies. Serrated polyps in the proximal colon are associated with an increased risk of future colonic neoplasia, comparable to having a baseline advanced adenoma. CONCLUSIONData on adenoma features and risk of future adenomas and CRC are compelling yet modest in absolute effect size. Future research should refine this risk stratification.

关键词： Colon adenoma Colorectal cancer screening Surveillance Colonoscopy

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Stable ischemic heart disease in the older adults

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Journal of Geriatric Cardiology 2016年第2期13卷 109-114页

作者： Xuming DAI Jan Busby-Whitehead Daniel e Forman karen P Alexander Division of Cardiology University of North Carolina at Chapel Hill Chapel Hill North Carolina USA Division of Geriatric Medicine Center for Aging and Health University of North Carolina at Chapel Hill North Carolina USA Section of Geriatric Cardiology University of Pittsburgh Medical Center Geriatrics Research Education and Clinical Center VA Pittsburgh Healthcare System Pittsburgh PA USA Division of Cardiology Duke University Medical Center Durham North Carolina USA

1 Introduction Ischemic heart disease is caused by atherosclerotic and/or thrombotic obstruction of coronary arteries. Clinical spec- trum of ischemic heart disease expands from asymptomatic atherosclerosis of coronary arteries to acute coronary syn- dromes （ACS） including unstable angina, acute myocardial infarction （non-ST elevation myocardial infarction and ST elevation myocardial infarction）. Stable ischemic heart dis- ease （SIHD） refers to patients with known or suspected SIHD who have no recent or acute changes in their symp- tomatic status, suggesting no active thrombotic process is underway.

关键词： Aging Coronary artery disease Older adults Risk assessment Stable ischemic heart disease

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Natal dispersal in a social landscape： Considering individual behavioral phenotypes and social environment in dispersal ecology

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Current Zoology 2015年第3期61卷 543-556页

作者： Tina W. WeY Orr SPIeGeL Pierre-Olivier MONTIGLIO karen e. MABRY Biology Department New Mexico State University Las Cruces NM 88003 USA Department of environmental Science & Policy University of California at Davis Davis CA 95616 USA

Natal dispersal, the movement of an organism from its birthplace to the site of first reproduction, is fundamental to many ecological and evolutionary processes. Mechanistically, individual dispersal decisions can depend on both individual phe- notype and environmental cues. In particular, many established evolutionary theories of dispersal highlight the importance of the social environment. More recent research in behavioral ecology has focused on the importance of individual behavioral pheno- types. We reviewed the literature on individual behavioral phenotypes and dispersal and suggest that how individual behavioral phenotypes interact with the immediate social environment experienced by individuals in influencing dispersal is still poorly un- derstood, despite growing interest. We found that very few studies had examined the interaction of individual behavioral pheno- types and social factors, and behavioral phenotypes related to social tendencies were less commonly measured than were beha- vioral phenotypes related to exploration or response to risk. Further, and unsurprisingly, studies on social behavioral phenotypes and dispersal behaviors during the transience stage of dispersal were underrepresented compared to the departure or settlement stages. Future studies in this area should aim to＂ a） make explicit links between behavioral traits and their proposed effects on dispersal decisions throughout multiple stages of dispersal, b） integrate more continuous dispersal variables, and c） consider the effects of the spatial distribution and phenotypes of conspecifics （i.e., the social landscape） encountered by individual dispersers

关键词： Animal dispersal Animal personality Behavioral syndromes Individual differences Social landscape

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effects of historic wildfire and prescribed fire on site occupancy of bats in Shenandoah National Park,Virginia,USA

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Journal of Forestry Research 2020年第4期31卷 1255-1270页

作者： Lauren V.Austin Alexander Silvis W.Mark Ford karen e.Powers Department of Fish and Wildlife Conservation Virginia TechBlacksburgVA 24061USA Resource environmental Solutions WarrentonVA 20187USA U.S.Geological Survey Virginia Cooperative Fish and Wildlife Research UnitBlacksburgVA 24061USA Biology Department Radford UniversityRadfordVA 24141USA

Given the likelihood of regional extirpation of several once-common bat species in eastern North America from white-nose syndrome,it is critical that the impacts of forest management activities,such as prescribed fire,are known in order to minimize potentially additive negative effects on bat *** wildfires may offer a suitable surrogate to assess long-term burn impacts on bats for planning,implementing and assessing burn *** examine the effects of historic fire on bats,we sampled bat activities at 24 transect locations in burned and unburned forest stands in the central Appalachian Mountains of Shenandoah National Park(SNP),Virginia,*** was limited evidence of positive fire effects over time on hoary bats(Lasiurus cinereus Beauvois)and big brown bats(eptesicus fuscus Beauvois)***,there were few or mostly equivocal relationships of bat occupancy relative to burn conditions or time since fire in SNP across species using a false-positive occupancy *** results suggest that fire does not strongly affect bat site occupancy short-or long-term in the central Appalachians.

关键词： Appalachian mountains Bats False-positive occupancy Prescribed fire Wildfire

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