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Outcomes and management of viral hepatitis and human immunodeficiency virus co-infection in liver transplantation

Outcomes and management of viral hepatitis and human immunodeficiency virus co-infection in liver transplantation

作     者:Stephen E Congly Karen E Doucette Carla S Coffin 

作者机构:Liver UnitDivision of Gastroenterology and HepatologyUniversity of CalgaryCalgaryAB T2N 4Z6Canada Division of Infectious DiseasesUniversity of AlbertaEdmontonAB T6G 2R3Canada 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2014年第20卷第2期

页      面:414-424页

核心收录:

学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主  题:Hepatitis B virus Human immunodeficiency virus co-infection Hepatitis C virus Co-infection Liver transplantation 

摘      要:Liver transplantation for human immunodeficiency virus(HIV)positive patients with viral hepatitis co-infection is increasingly offered in many North American and European liver transplant *** studies have demonstrated acceptable post-transplant outcomes and no increased risk of HIV complications in patients coinfected with hepatitis B virus(HBV).However,liver transplantation in HIV positive patients with hepatitis C virus(HCV)has poorer outcomes overall,requiring careful selection of *** review aims to summarize the published literature on outcomes after transplant in HIV patients with HBV or HCV related end-stage liver disease and recommendations for *** particular the pre-transplant factors impacting outcomes in HCV/HIV co-infected candidates and importance of multidisciplinary management will be discussed.

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