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The utilization of chitosan/Bletilla striata hydrogels to elevate anti-adhesion,anti-inflammatory and pro-angiogenesis properties of polypropylene mesh in abdominal wall repair

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Regenerative Biomaterials 2024年第4期3卷 111-124页

作者： Yuntao Di Lu Wang Wei He Shuyan Liu Yuqi He Jie Liao Ruihong Zhang Lan yin Zhiwei Xu Xiaoming Li Department of Neurosurgery The Fourth Central Hospital of Baoding CityBaoding 072350China Research Center for Biomedical Engineering Medical Innovation&Research DivisionChinese PLA General HospitalKey Laboratory of Biomedical Engineering and Translational MedicineMinistry of Industry and Information TechnologyBeijing 100853China Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijing 100083China College of Lab Medicine Hebei North UniversityZhangjiakou 075000China Key Laboratory of Advanced Materials of Ministry of Education Tsinghua UniversityBeijing 100084China

Polypropylene(PP)mesh is commonly used in abdominal wall repair due to its ability to reduce the risk of organ damage,infections and other ***,the PP mesh often leads to adhesion formation and does not promote functional tissue *** this study,we synthesized one kind of aldehyde Bletilla striata polysaccharide(BSPA)modified chitosan(CS)hydrogel based on Schiff base *** hydrogel exhibited a porous network structure,a highly hydrophilic surface and good *** wrapped the PP mesh inside the hydrogel and evaluated the performance of the resulting composites in a bilateral 1×1.5cm abdominal wall defect model in *** results of gross observation,histological staining and immunohistochemical staining demonstrated the positive impact of the CS hydrogel on anti-adhesion and wound healing ***,the addition of BSPA to the CS hydrogel further improved the performance of the composites in vivo,promoting wound healing by enhancing collagen deposition and capillary *** study suggested that the BSPA-modified CS hydrogel significantly promoted the anti-adhesion,anti-inflammatory and pro-angiogenesis properties of PP meshes during the healing ***,this work offers a novel approach to the design of abdominal wall repair patches.

关键词： abdominal wall wound healing hydrogel Bletilla striata anti-adhesion

The Application of GGE Biplot Analysis for Evaluating Test Locations and Mega-Environment Investigation of Cotton Regional Trials

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Journal of Integrative Agriculture 2014年第9期13卷 1921-1933页

作者： XU Nai-yin fok Michel ZHANG Guo-wei LI Jian ZHOU Zhi-guo Key Laboratory of Corp Growth Regulation Ministry of Agriculture/Nanjing Agricultural University Key Laboratory of Cotton and Rapeseed Ministry of Agriculture/Institute of Industrial Crops Jiangsu Academy of Agriculture Sciences Center of International Cooperation on Agronomic Research for Development (CIRAD) TA B102/0234398 Montpellier Cedex 5France

In the process to the marketing of cultivars, identification of superior test locations within multi-environment variety trial schemes is of critical relevance. It is relevant to breeding organizations as well as to governmental organizations in charge of cultivar registration. Where competition among breeding companies exists, effective and fair multi-environment variety trials are of utmost importance to motivate investment in breeding. The objective of this study was to use genotype main effect plus genotype by environment interaction（GGE） biplot analysis to evaluate test locations in terms of discrimination ability, representativeness and desirability, and to investigate the presence of multiple mega-environments in cotton production in the Yangtze River Valley（YaRV）, China. Four traits（cotton lint yield, fiber length, lint breaking tenacity, micronaire） and two composite selection indices were considered. It was found that the assumption of a single mega-environment in the YaRV for cotton production does not hold. The YaRV consists of three cotton mega-environments： a main one represented by 11 locations and two minor ones represented by two test locations each. This demands that the strategy of cotton variety registration or recommendation must be adjusted. GGE biplot analysis has also led to the identification of test location superior for cotton variety evaluation. Although test location desirable for selecting different traits varied greatly, Jinzhou, Hubei Province, China, was found to be desirable for selecting for all traits considered while Jianyang, Sichuan Province, China, was found to be desirable for none.

关键词： cotton multi-environmental trial GGE biplot test location mega-environment

Nitrite-driven anaerobic ethane oxidation

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Environmental Science and Ecotechnology 2024年第5期21卷 361-368页

作者： Cheng-Cheng Dang yin-Zhu Jin Xin Tan Wen-Bo Nie Yang Lu Bing-Feng Liu De-Feng Xing Nan-Qi Ren Guo-Jun Xie State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin150090China Key Laboratory of the Three Gorges Region's Eco-Environment Ministry of EducationCollege of Environment and EcologyChongqing UniversityChongqing400044China Water Innovation and Smart Environment Laboratory School of Civil and Environmental EngineeringFaculty of EngineeringQueensland University of TechnologyBrisbaneQueensland4001Australia

Ethane,the second most abundant gaseous hydrocarbon in vast anoxic environments,is an overlooked greenhouse *** anaerobic oxidation of ethane can be driven by available electron acceptors such as sulfate and ***,despite nitrite being a more thermodynamically feasible electron acceptor than sulfate or nitrate,little is known about nitrite-driven anaerobic ethane *** this study,a microbial culture capable of nitrite-driven anaerobic ethane oxidation was enriched through the long-term operation of a nitrite-and-ethane-fed *** continuous operation,the nitrite removal rate and the theoretical ethane oxidation rate remained stable at approximately 25.0 mg NO_(2) eN L^(-1) d^(-1) and 11.48 mg C2H6 L^(-1) d^(-1),*** tests demonstrated that ethane is essential for nitrite removal in this microbial *** function analysis revealed that a species affiliated with a novel genus within the family Rhodocyclaceae,designated as'Candidatus Alkanivoras nitrosoreducens',may perform the nitrite-driven anaerobic ethane *** the proposed metabolic model,despite the absence of known genes for ethane conversion to ethyl-succinate and succinate-CoA ligase,'***'encodes a prospective fumarate addition pathway for anaerobic ethane oxidation and a complete denitrification pathway for nitrite reduction to *** findings advance our understanding of nitrite-driven anaerobic ethane oxidation,highlighting the previously overlooked impact of anaerobic ethane oxidation in natural ecosystems.

关键词： Anaerobic ethane oxidation Denitrification Microbial culture Fumarate addition pathway Greenhouse gas

Probing quantum causality with geometric asymmetry in spatial-temporal correlations

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Science China(Information Sciences) 2024年第9期67卷 294-305页

作者： Yu MENG Zheng-Hao LIU Zhikuan ZHAO Peng yin Yi-Tao WANG Wei LIU Zhi-Peng LI Yuan-Ze YANG Zhao-An WANG Jin-Shi XU Shang YU Jian-Shun TANG Chuan-Feng LI Guang-Can GUO CAS Key Laboratory of Quantum Information University of Science and Technology of China CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of China Department of Computer Science Eidgen?ssische Technische Hochschule Zürich Hefei National Laboratory Department of Physics Imperial College London Research Center for Quantum Sensing Zhejiang Lab

Causation promotes the understanding of correlation to an advanced stage by elucidating its underlying mechanism. Although statisticians have specified the possible causal relations among correlations,inferring causal structures is impossible from only the observed correlations in the classical world. Quantum correlations encapsulating the most defining aspects of quantum physics have taken a new turn for the causal inference problem — the two-point spatial and temporal quantum correlations with observationally discernible characteristics correspond exactly to the two most basic causal structures. However, a direct causal interpretation for quantum correlations has only been established in very limited cases. Here, we explore to what extent quantum correlations promote causal inference. Theoretically, we have found that the distinguishable causal regime of two-point Pauli correlations can be expanded from a single value to an asymmetric interval, and the causal structures determining the quantum correlations can be interpreted by a simple distance criterion. Experimentally, we have devised and implemented a versatile non-unital quantum channel in an optical architecture to directly observe such an asymmetric interval. The setup enabled quantum causal inference without any requirement of active intervention, which is impossible in the classical realm. Our work facilitates the identification of causal links among quantum variables and provides insight into characterizing causation and spatial-temporal correlation in quantum mechanics.

关键词： causality quantum information quantum channel channel-state duality non-unital channel

D53 represses rice blast resistance by directly targeting phenylalanine ammonia lyases

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Journal of Integrative Plant Biology 2024年第9期66卷 1827-1830页

作者： Haitao Ye Qingqing Hou Haitao Lv Hui Shi Duo Wang Yujie Chen Tangshuai Xu Mei Wang Min He Junjie yin Xiang Lu Yongyan Tang Xiaobo Zhu Lijuan Zou Xuewei Chen Jiayang Li Bing Wang Jing Wang State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengdu 611130China Key Laboratory of Seed Innovation Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China Yazhouwan National Laboratory Sanya 572024China

Phytohormones play important roles in orchestrating plantimmune responses to pathogen ***(SLs),a group of carotenoid-derived phytohormones,modulate diverse biological processes in plants,including shoot branching,plant height,root architecture,leaf senescence,seed germination of parasitic plants,and symbiosis of arbuscular mycorrhizal fungi(Burger and Chory,2020).Recently,increasing evidence has indicated potential roles for SLs in regulating responses against biotic stresses,including defense responses against certain pathogenic fungi and bacteria in roots and leaves(Yi et al.,2023).

关键词： ammonia resistance branching

Mini-review on initiatives to interfere with the propagation and clearance of alphasynuclein in Parkinson’s disease

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Translational Neurodegeneration 2017年第1期6卷 333-337页

作者： Daniel Kam yin Chan ying Hua Xu Luke kar Man Chan Nady Braidy George D.Mellick Department of Aged Care and Rehabilitation Bankstown HospitalBankstownNSW 2200Australia Ingham Institute LiverpoolNSW 2170Australia University of New South Wales Faculty of MedicineSydneyAustralia Faculty of Medical Science Griffith UniversityNathanQLDAustralia Griffith Institute for Drug Discovery Griffith UniversityNathanQLDAustralia

In this mini-review,we summarize recent findings relating to the prion-like propagation ofα-synuclein(α-syn)and the development of novel therapeutic strategies to target synucleinopathy in Parkinson’s disease(PD).We link the Braak’s staging hypothesis of PD with the recent evidence from in-vivo and in-vitro studies for the prion-like cell-to-cell propagation ofα-syn(via exocytosis and endocytosis).The classical accumulation of aggregatedα-syn in PD may result from an increased production or a failure in the mechanisms of clearance ofα-*** discuss novel agents,currently in clinical trial for PD including the ones that impact the aggregation ofα-syn and others that interfere withα-syn endocytosis as a means to target the progression of the disease.

关键词： Parkinson’s disease α-synuclein Endocytosis Aggregation

Metabolic syndrome and benign prostatic hyperplasia:An update

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Asian Journal of Urology 2017年第3期4卷 164-173页

作者： Ho-yin Ngai kar-Kei Steffi Yuen Chi-Man Ng Cheung-Hing Cheng Sau-Kwan Peggy Chu Division of Urology Department of SurgeryQueen Elizabeth HospitalHong KongChina Division of Urology Department of SurgeryTuen Mun HospitalHong KongChina

Metabolic syndrome(MetS)is a cluster of metabolic abnormalities related to central adiposity and insulin *** importance is increasingly recognized as it associates with increased risks of metabolic and cardiovascular *** metabolic aberrations of MetS may lead to development of benign prostatic hyperplasia(BPH)and lower urinary tract symptoms(LUTS)in men.A 26.5%-55.6% prevalence of MetS in men with LUTS was reported in worldwide *** the exact biological pathway is not clear yet,insulin resistance,increased visceral adiposity,sex hormone alterations and cellular inflammatory reactions played significant roles in the related pathophysiological *** should recognize the cardiovascular and metabolic impacts of MetS in men with LUTS,early risk factors optimization and use of appropriate medical therapy may possibly alter or slower the progression of LUTS/BPH,and potentially avoid unnecessary morbidities and mortalities from cardiovascular and metabolic diseases for those men.

关键词： Inflammation Insulin resistance Lower urinary tract symptoms Metabolic syndromeX Prostatic hyperplasia

RNA editing machinery in plant organelles

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Science China(Life Sciences) 2018年第2期61卷 162-169页

作者： Junjie Yan Qunxia Zhang Ping yin National Key Laboratory of Crop Genetic Improvement and National Centre of Plant Gene Research Huazhong Agricultural University

RNA editing is a type of post-transcriptional modification that includes nucleotide insertion/deletion or conversion. Different categories of RNA editing have been widely observed in distinct RNAs from divergent organisms. In flowering plants, RNA editing usually alters cytidine to uridine in plastids and mitochondria, playing important roles in various plant developmental processes, including organelle biogenesis, adaptation to environmental changes, and signal transduction. Numerous studies have demonstrated that a number of factors are involved in plant RNA editing, such as pentatricopeptide repeat(PPR) proteins, multiple organelle RNA editing factors(MORF, also known as RIP), organelle RNA recognition motif(ORRM) containing proteins,protoporphyrinogen IX oxidase 1(PPO1) and organelle zinc finger 1(OZ1). These factors play diverse roles in plant RNA editing due to their distinct characteristics. In this review, we discuss the functional roles of the individual editing factors and their associations in plant RNA editing.

关键词： RNA editing editosome plant organelles

Cross-Ice Acoustic Communication:Cascade Acoustic Channel Model and Experimental Results

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China Communications 2021年第2期18卷 228-240页

作者： Jingwei yin Wei Men Guangping Zhu Xiao Han Acoustic science and Technology laboratory Harbin Engineering UniversityHarbin 150001China Key Laboratory of Marine Information Acquisition and Security(Harbin Engineering University) Ministry of Industry and Information TechnologyHarbin 150001China College of Underwater Acoustic Engineering Harbin Engineering UniversityHarbin 150001China

Cross-ice acoustic information transmission is an effective means of communication in polar sea areas covered by ***,the channel is extremely complicated because of the combined influence of water,ice,and *** on the normalmode theory,this paper establishes a cascade acoustic channel(CAC)model for the transmission of underwater acoustic waves across ice *** model can calculate the displacement response of the ice layer’s upper surface by separating the upward waves from normal modes in the water and multiplying it by a transmission coefficient *** relationship between the displacement response of the upper surface of ice layer and the acoustic frequency is calculated by the finite-element method,and the calculation result was consistent with that of the CAC *** verify the applicability of the model,a cross-ice acoustic communication experiment was conducted in Songhua River in January *** results show the energy of the acoustic signals received by geophones is closely related to sound frequency and crossice acoustic communication is *** result of present research is important for understanding crossice acoustic channel characteristics and developing future cross-ice acoustic communication in polar sea areas.

关键词： cross-ice acoustic communication normal mode CAC model transmission coefficient