What constitutes failure of medical therapy in the changing landscape of Crohn's disease?
作者机构：Division of Colorectal SurgeryDepartment of SurgeryWestmead HospitalSydneyNew South WalesAustralia Westmead Clinical SchoolThe University of SydneySydneyNew South WalesAustralia
出 版 物：《Laparoscopic, Endoscopic and Robotic Surgery》 (腔镜、内镜与机器人外科（英文）)
年 卷 期：2022年第5卷第4期
页 面：158-160页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Crohn's disease Phlegmon Laparoscopic surgery Failure of medical therapy Ileocecal resection
摘 要：The management of Crohn s disease has evolved rapidly in the era of immunomodulators and *** this,a significant proportion of patients with Crohn s disease ultimately require surgical *** of the indications for operative management includes failure of medical *** report two cases of patients with complicated Crohn s disease who have exhausted medical therapy and failed medical *** both cases,the patients developed large complex intra-abdominal phlegmons and intractable symptoms of intermittent pain,partial obstruction and/or infectious complications requiring operative *** s disease can present with a wide spectrum of *** the complexity of management in Crohn s disease,it is important for both physicians and surgeons to be aware of what constitutes failure of medical therapy and when it may be important to consider surgical involvement.
维普期刊数据库