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Gastroenterology Report 2022年第1期10卷 650-652页

作者： Fumiue Harada kana yamamoto Tomoki Matsuda Chika yamamoto Yuta Tani Mutsuko Ohnishi Morihito Takita Tetsuya Tanimoto Masahiro Kami Ryusaburo Shineha Department of Internal Medicine Soma Central HospitalSomaFukushimaJapan Department of Disaster and Comprehensive Medicine Fukushima Medical UniversityFukushimaFukushimaJapan Department of Radiation Health Management Fukushima Medical UniversityFukushimaFukushimaJapan Research Division Medical Governance Research InstituteMinatoTokyoJapan

Introduction SARS-CoV-2 vaccination is an effective means to prevent severe illness and death due to SARS-CoV-2 infection[1].Vaccine safety has been carefully monitored to be sure that the benefit outweighs the risk of adverse events(AEs).Common AEs of the BNT162b2 mRNA vaccine,for example,include fatigue(45%),headache(40%),and chills(28%)after the first administration in accordance with the adult phase Ⅲ clinical trial[1].

关键词： headache death administration

An Effective Runge-Kutta Optimizer Based on Adaptive Population Size and Search Step Size

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Computers, Materials & Continua 2023年第9期76卷 3443-3464页

作者： Ala kana Imtiaz Ahmad Department of Computer Engineering College of Engineering and PetroleumKuwait UniversityKuwait CityKuwait

A newly proposed competent population-based optimization algorithm called RUN,which uses the principle of slope variations calculated by applying the Runge Kutta method as the key search mechanism,has gained wider interest in solving optimization ***,in high-dimensional problems,the search capabilities,convergence speed,and runtime of RUN *** work aims at filling this gap by proposing an improved variant of the RUN algorithm called the *** size plays a vital role in both runtime efficiency and optimization effectiveness of metaheuristic *** the original RUN where population size is fixed throughout the search process,Adaptive-RUN automatically adjusts population size according to two population size adaptation techniques,which are linear staircase reduction and iterative halving,during the search process to achieve a good balance between exploration and exploitation *** addition,the proposed methodology employs an adaptive search step size technique to determine a better solution in the early stages of evolution to improve the solution quality,fitness,and convergence speed of the original ***-RUN performance is analyzed over 23 IEEE CEC-2017 benchmark functions for two cases,where the first one applies linear staircase reduction with adaptive search step size(LSRUN),and the second one applies iterative halving with adaptive search step size(HRUN),with the original *** promote green computing,the carbon footprint metric is included in the performance evaluation in addition to runtime and *** results based on the Friedman andWilcoxon tests revealed that Adaptive-RUN can produce high-quality solutions with lower runtime and carbon footprint values as compared to the original RUN and three recent ***,with its higher computation efficiency,Adaptive-RUN is a much more favorable choice as compared to RUN in time stringent applications.

关键词： Optimization Runge Kutta(RUN) metaheuristic algorithm exploration exploitation population size adaptation adaptive search step size

Hazard Mitigation Planning for Debris flow Based on Numerical Simulation Using kanako Simulator

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Journal of Mountain Science 2012年第4期9卷 529-537页

作者： LIU Jinfeng NAKATANI kana MIZUYAMA Takahisa Key Laboratory of Mountain Surface Process and Hazards Institute of Mountain Hazards and EnvironmentChineseAcademy of SciencesChengdu 610041China Department of Erosion Control Engineering Kyoto UniversityKyoto 6068502Japan

Debris flow often causes enormous loss to life and property,especially on alluvial *** structures such as retention check dams are essential to reduce the *** hazard mitigation evaluation and planning it is of significance to determine the location,size and type of dam and the effects of damage *** present a numerical simulation method using kanako simulator for hazard mitigation planning of debris flow disaster in Tanjutani Gully,Kyoto City,*** simulations were carried out for three situations:1) the simulations of erosion,deposition,hydrograph changing and inundation when there were no mitigation measures;2) the simulations of check dams in four locations(470 m,810 m,1,210 m and 1,610 m from the upstream end) to identify the best location;3) the simulations of check dams of three types(closed,slit and grid) to analyze their effects on sediment trapping and discharge *** on the simulations,it was concluded that two closed check dams(located at 470 m and 1,610 m from the upstream end) in the channel and a drainage channel on the alluvial fan can reduce the risk on the alluvial fan to an acceptable level.

关键词： Hazard mitigation planning Debrisflow Numerical simulation kanako Simulator

A Support System of Sightseeing Tour Planning Using Public Transportation in Japanese Rural Areas

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Journal of Civil Engineering and Architecture 2020年第6期14卷 316-332页

作者： kana Ikizawa-Naitou Kayoko yamamoto Graduate School of Informatics and Engineering University of Electro-CommunicationsTokyo 182-8585Japan

Though most of tourists tend to visit multiple sightseeing spots during their sightseeing tours,it is difficult for them to efficiently acquire information necessary for their sightseeing tour ***,in rural area,many people hope to use public transportation which has not developed as much as in urban *** present study aims to design and develop a support system of sightseeing tour planning in Japanese rural areas,adopting the information related to real timetables of public transportation on both the sea and the ground,and genetic algorism(GA).The system was developed integrating moving route recommendation system,web-geographic information systems(Web-GIS),and augmented reality(AR)***,Kagawa Prefecture in the western part was selected as the operation target *** operation of the system was conducted for two months,targeting those inside and outside the operation target area,and web questionnaire surveys were *** the evaluation results based on the web questionnaire surveys,the usefulness of all the original functions as well as of the entire system was ***,though some users could not easily use the system,it is expected that they will get used to utilizing it by their continuous use.

关键词： Sightseeing tour planning Web-GIS moving route recommendation system AR GA public transportation

Case study of debris flow disaster scenario caused by torrential rain on Kiyomizu-dera, Kyoto, Japan - using Hyper kanaKO system

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Journal of Mountain Science 2016年第2期13卷 193-202页

作者： kana NAKATANI Satoshi HAYAMI Yoshifumi SATOFUKA Takahisa MIZUYAMA Department of Erosion Control Engineering Kyoto University Kyoto 606-8502 Japan CTI Engineering Co. Ltd. Osaka 541-0045 Japan Department of Civil Engineering Ritsumeikan University Shiga 606-8502 Japan National Graduate Institute for Policy Studies Tokyo106-8677 Japan

This paper presents debris-flow numerical simulations using the Hyper kanaKO system,developed by the *** system uses the debris flow simulator kanaKO 2D equipped with a graphical user interface(GUI);hence,a user can easily produce appropriate landform data for simulations using standard laser profiler data,and visualize the results using a *** kanaKO was applied to the streams around Kiyomizu-dera in Kyoto,***-dera is a famous temple in Japan which is visited by numerous tourists throughout the *** simulated a disaster scenario of debris flow caused by torrential *** set the hydrograph using rainfall intensity data,and set the landform data using information from the Geospatial Information Authority of Japan(GSI) and a digital elevation model(DEM).We evaluated different mesh sizes and also used a digital surface model(DSM) to consider the building *** simulation results showed that with small mesh size,the debris flowmoved through the roads,which seems realistic for a disaster *** buildings were considered,the flow direction changed,and a 1-m flow depth,which was deeper than in other cases,appeared in the flow *** may pose a dangerous situation for evacuations.

关键词： Debris flow Simulation GIS Hyper kanaKO system Torrential rain Kiyomizu-dera

Influence of Housing and Urban Development on Debris Flow Flooding and Deposition

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Journal of Mountain Science 2013年第2期10卷 273-280页

作者： kana NAKATANI Yuki OKUYAMA Yuji HASEGAWA Yoshifumi SATOFUKA Takahisa MIZUYAMA Graduate School of Agriculture Kyoto UniversityKitashirakawa Oiwake-choSakyo-kuKyoto City606-8502Japan National Institute for Land and Infrastructure Management AsahiTsukuba CityIbaraki305-0804Japan Civil Engineering Research Laboratory 904-1 TohigashiTsukuba CityIbaraki300-2633Japan Department of Civil Engineering Ritsumeikan University1-1-1 Noji-higashiKusatsu CityShiga525-8577Japan

Debris flows form deposits when they reach an alluvial fan until they eventually ***,houses located in the alluvial fan might affect the debris flow flooding and deposition *** previous studies have considered the effects of houses on debris flow flooding and *** study conducted model experiments and numerical simulations using the kanako2D debris flow simulator to determine the influence of houses on debris flow flooding and *** model experiments showed that when houses are present,the debris flow spreads widely in the cross direction immediately upstream of the houses,especially when the flow discharge is large or the grain size is *** located in the alluvial fan also influence the deposition *** presence of houses led to flooding and deposition damage in some places and reduced the damage in *** simulation also demonstrated the influence of *** the model experiment and the simulation showed that houses change the flooding and deposition areas.

关键词： Debris flow Alluvial fan House Modelexperiment Numerical simulation

Multi-Physics CFD Simulations in Engineering

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Journal of Thermal Science 2013年第4期22卷 287-293页

作者： Makoto yamamoto Tokyo University of Science Department of Mechanical Engineering 6-3-1 NiijukuKatsushika-ku Tokyo 125-8585 Japan

Nowadays Computational Fluid Dynamics （CFD） software is adopted as a design and analysis tool in a great number of engineering fields. We can say that single-physics CFD has been suffciently matured in the practical point of view. The main target of existing CFD software is single-phase flows such as water and air. However, many multi-physics problems exist in engineering. Most of them consist of flow and other physics, and the interactions between different physics are very important. Obviously, multi-physics phenomena are critical in devel- oping machines and processes. A multi-physics phenomenon seems to be very complex, and it is so difficult to be predicted by adding other physics to flow phenomenon. Therefore, multi-physics CFD techniques are still under research and development. This would be caused from the facts that processing speed of current computers is not fast enough for conducting a multi-physics simulation, and furthermore physical models except for flow physics have not been suitably established. Therefore, in near future, we have to develop various physical models and ef- ficient CFD techniques, in order to success multi-physics simulations in engineering. In the present paper, I will describe the present states of multi-physics CFD simulations, and then show some numerical results such as ice accretion and electro-chemical machining process of a three-dimensional compressor blade which were obtained in my laboratory. Multi-physics CFD simulations would be a key technology in near future.

关键词： Computational fluid dynamics Multi-physics Engineering problems

SYNTHESIS AND CHARACTERIZATION OF SOLUBLE POLYPHENYLENE COMPOSED OF p-PHENYLENE AND m-PHENYLENE UNITS

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Chinese Journal of Polymer Science 2002年第4期20卷 333-337页

作者： Takakazu yamamoto Chemical Resources Laboratory Tokyo Institute of Technology Tokyo Japan

NiCl2(bpy) catalyzed polycondensation between p-dibromobenzene and m-dibromobenzene has been carried out under various conditions. The polycondensation endows the copolymer with an M-n of 2300 (by GPC, polystyrene standards) and good solubility in organic solvents. The fluorescence spectra of the copolymer measured with tetrahydrofuran solution shows an emission maximum (lambda(max)) at 372.8 nm, whereas for the film the maximum shifts to 436.6 nm.

关键词： polyphenylene copolycondensation conjugated polymer

Flow separation control by using bowed blade in highly loaded turbine cascades

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Science China(Technological Sciences) 2009年第6期52卷 1471-1477页

作者： yamamoto Atsumasa Japan Aerospace Exploration Agency

Due to the serious flow separations and centralized vortices,there are high secondary losses in highly loaded *** is imperative to find measures to control the flow separation and vortices hence improve the turbine *** paper reports our recent progress on flow separation and vor-tices control in highly loaded turbine cascades by using bowed *** sets of highly loaded tur-bine cascades with the turning angles of 113° and 160°,and each with 7 bowed blade angles 0°(straight),±10°,±20° and ±30° were experimentally *** internal flow field measurement and flow visualization on the blade surfaces were conducted,and the effects of blade bowing on the flow topology,distribution of vorticity and the flow energy loss were *** results show that,for the cascade with the turning angle of 113°,the appropriately positive bow angle could reduce the flow energy loss;whereas for the cascade with the turning angle of 160°,the well selected negative bow angle can give the better aerodynamic performance.

关键词： turbine cascade turning angle flow separation bowed blade

Prevention of recurrence after surgery for Crohn's disease: Efficacy of infliximab

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World Journal of Gastroenterology 2010年第43期16卷 5405-5410页

作者： Takayuki yamamoto Inflammatory Bowel Disease Center and Department of Surgery Yokkaichi Social Insurance Hospital

After surgery for Crohn's disease (CD), early endoscopic lesions are frequently observed despite no symptomatic recurrence. The severity of lesions found at postoperative endoscopy is reported to be a strong predictive factor for future clinical recurrence. If endoscopic lesions in the early postoperative period can be reduced with medications, symptomatic recurrence will likely be delayed and decreased. Before the introduction of biologic therapies, various medications were used for the maintenance of clinical remission after surgery; however, few demonstrated consistent efficacy. Infliximab is a recombinant anti-tumor necrosis factor-α antibody. Although infliximab is one of the most effective medications in the management of CD, its efficacy for early endoscopic lesions after surgery has not yet been assessed. The author and colleagues recently conducted a prospective study in order to investigate the impact of infliximab on early endoscopic lesions after resection for CD. We found that infliximab therapy showed clear suppressive effects on clinical and endoscopic disease activity in patients with early endoscopic lesions after resection.

关键词： Crohn’s disease Postoperative recurrence Endoscopic lesion Infliximab