检索结果-南通市图书馆

Bandgap characteristics analysis and graded design of a novel metamaterial for flexural wave suppression

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 1-24页

作者： Fan yang Zhaoyang MA Xingming GUO Shanghai Key Laboratory of Mechanics in Energy Engineering Shanghai Institute of Applied Mathematics and Mechanics School of Mechanics and Engineering ScienceShanghai University Shanghai Institute of Aircraft Mechanics and Control

A novel elastic metamaterial is proposed with the aim of achieving lowfrequency broad bandgaps and bandgap regulation. The band structure of the proposed metamaterial is calculated based on the Floquet-Bloch theorem, and the boundary modes of each bandgap are analyzed to understand the effects of each component of the unit cell on the bandgap formation. It is found that the metamaterials with a low elastic modulus of ligaments can generate flexural wave bandgaps below 300 Hz. Multi-frequency vibrations can be suppressed through the selective manipulation of bandgaps. The dual-graded design of metamaterials that can significantly improve the bandgap width is proposed based on parametric studies. A new way that can regulate the bandgap is revealed by studying the graded elastic modulus in the substrate. The results demonstrate that the nonlinear gradient of the elastic modulus in the substrate offers better bandgap performance. Based on these analyses, the proposed elastic metamaterials can pave the way for multi-frequency vibration control, low-frequency bandgap broadening, and bandgap tuning.

关键词：

氯霉素ELISA可视化微阵列芯片检测试剂盒评价研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国乳品工业 2017年第5期45卷 47-50页

作者：杜兵耀文芳臧长江邵伟李昊张养东杨开伦余雄姜金斗巩军新疆农业大学动物科学学院乌鲁木齐830052 中国农业科学院北京畜牧兽医研究所北京100193 农业部乳品质量监督检验测试中心(哈尔滨) 哈尔滨150090

为了了解氯霉素ELISA可视化微阵列芯片检测试剂盒的有效性和可靠性,从灵敏度、特异性、准确度、可重复性、检出限、耐变性、批间变异等方面进行了评价,结果表明该试剂盒在测试范围内线性回归良好,相关系数R2可达0.9943,与结构相似的甲... 详细信息

为了了解氯霉素ELISA可视化微阵列芯片检测试剂盒的有效性和可靠性,从灵敏度、特异性、准确度、可重复性、检出限、耐变性、批间变异等方面进行了评价,结果表明该试剂盒在测试范围内线性回归良好,相关系数R2可达0.9943,与结构相似的甲砜霉素、氟甲砜霉素的交叉反应率均小于1%,批间变异系数小于20%,牛奶中的平均回收率为108.5%,检出限为0.067μg/L,该试剂盒有较好的准确性、特异性与重复性,耐变性与批间变异均在可接受范围内,可用于牛奶样品中氯霉素的残留检测。

关键词：氯霉素 ELISA 试剂盒评价

高精料饲粮中添加烟酸对绵羊瘤胃内乳酸代谢及其相关酶活性的影响

在线全文

学校读者我要写书评

暂无评论

动物营养学报 2023年第10期35卷 6507-6515页

作者：成志强管勤超臧长江陈开旭刘建成焦毅灵李凤鸣李晓斌杨开伦雒秋江新疆农业大学动物科学学院新疆肉乳用草食动物营养实验室乌鲁木齐830052

本试验旨在研究高精料饲粮中添加烟酸对绵羊瘤胃内乳酸代谢及其相关酶活性的影响。选取8月龄左右、体重(36.04±1.81)kg、体况相近且健康的哈萨克公羊24只,试验前安装好永久性瘤胃瘘管,随机分为4组,每组6只。对照组饲喂精粗比为70∶30... 详细信息

本试验旨在研究高精料饲粮中添加烟酸对绵羊瘤胃内乳酸代谢及其相关酶活性的影响。选取8月龄左右、体重(36.04±1.81)kg、体况相近且健康的哈萨克公羊24只,试验前安装好永久性瘤胃瘘管,随机分为4组,每组6只。对照组饲喂精粗比为70∶30的基础饲粮,试验Ⅰ、Ⅱ、Ⅲ组分别在对照组饲粮的基础上添加100、130和160 mg/d烟酸。试验期共18 d,其中预试期14 d,正试期4 d。结果显示:1)与对照组相比,试验Ⅱ组在饲喂后1 h时瘤胃液中L-乳酸浓度显著降低(P<0.05);试验Ⅱ、Ⅲ组在饲喂后3 h时瘤胃液中L-乳酸浓度极显著降低(P<0.01)。与对照组和试验Ⅰ组相比,试验Ⅱ组在饲喂后1 h时瘤胃液中D-乳酸浓度极显著降低(P<0.01)。与对照组相比,在饲喂后3 h时,试验Ⅱ、Ⅲ组血清中L-乳酸浓度极显著降低(P<0.01),D-乳酸浓度显著降低(P<0.05)。2)在饲喂后1 h时,对照组瘤胃液中乳酸脱氢酶活性显著高于试验Ⅱ组(P<0.05),在饲喂后3、5 h时,对照组极显著高于试验Ⅱ、Ⅲ组(P<0.01);饲喂后3 h时,试验Ⅱ组瘤胃液中氧化态烟酰胺腺嘌呤二核苷酸(NAD+)浓度极显著高于对照组(P<0.01),对照组瘤胃液中还原态烟酰胺腺嘌呤二核苷酸(NADH)浓度极显著高于试验Ⅱ、Ⅲ组(P<0.01)。3)在饲喂后1 h时,试验Ⅱ组瘤胃液中丙酮酸激酶活性极显著高于对照组(P<0.01),瘤胃液中苹果酸脱氢酶活性极显著高于对照组和试验Ⅰ组(P<0.01),瘤胃液中琥珀酸脱氢酶活性极显著高于对照组(P<0.01)。4)在饲喂后1 h时,试验Ⅱ组瘤胃液中丙酮酸浓度极显著高于对照组(P<0.01),试验Ⅱ、Ⅲ组瘤胃液中苹果酸浓度显著高于对照组(P<0.05),试验Ⅱ、Ⅲ组瘤胃液中琥珀酸浓度极显著高于对照组(P<0.01)。综上所述,高精料饲粮中添加烟酸提高了绵羊瘤胃液中NAD+浓度,丙酮酸激酶、苹果酸脱氢酶、琥珀酸脱氢酶活性以及丙酮酸、苹果酸和琥珀酸浓度,同时降低了瘤胃液和血清中L-乳酸、D-乳酸浓度。本试验条件下,绵羊高精料饲粮中烟酸的推荐添加量为130 mg/d。

关键词：烟酸绵羊 L-乳酸 D-乳酸乳酸代谢相关酶

La-doped Copper Nitride Films Prepared by Reactive Magnetron Sputtering

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2009年第2期25卷 233-236页

作者： Xinn＇ao Li Jianping yang Anyou Zuo Zuobin Yuan Zuli Liu kailun Yao College of Mathematic and Physics Nanjing University of Posts and Telecommunications Nanjing 210003 China School of Science Hubei Institute for Nationalities Enshi 445000 China Department of Physics Huazhong University of Science and Technology Wuhan 430074 China International Center of Material Physics Chinese Academy of Science Shenyang 110016 China

Copper nitride film （Cu3N） and La-doped copper nitride films （LaxCu3N） were prepared on glass substrates by reactive magnetron sputtering of a pure Cu and a pure La targets under N2 atmosphere. The results show that La-free film was composed of Cu3N crystallites with anti-ReO3 structure with （111） texture. The formation of the LaxCu3N films is affected strongly by La, and the peak intensity of the preferred crystalline [111]-orientation decreases with increasing the concentration of La. High concentration of La may prevent the formation of the Cu3N from crystallization. Compared with the Cu3N films, the resistivity of the LaxCu3N films have been decreased.

关键词： Copper Crystal nitride film La-doped copper nitride films Magnetron sputtering structure

Sex differences in aging and injured brain

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2901-2902页

作者： Jordan N.Williamson Yuan yang University of Illinois Urbana-Champaign Grainger College of EngineeringDepartment of BioengineeringUrbanaILUSA Carle Foundation Hospital Stephenson Family Clinical Research InstituteClinical Imaging Research CenterUrbanaILUSA University of Illinois Urbana-Champaign Beckman Institute for Advanced Science and TechnologyUrbanaILUSA Northwestern University Department of Physical Therapy and Human Movement SciencesChicagoILUSA

Background:The prevalence,age of onset,and symptomatology of traumatic brain injury,stroke,and neurodegenerative diseases(such as Alzheimer’s disease(AD),Parkinson’s disease,amyotrophic lateral sclerosis,and Huntington’s disease)differ substantially between males and *** higher prevalence of these brain disorders has been attributed to females having a greater longevity compared with *** one of the greatest risk factors of acquired brain injury(such as stroke,traumatic brain injury caused by fall)and neurodegenerative disease is age.

关键词： Huntington prevalence traumatic

补喂脂肪对放牧伊犁马泌乳量、乳成分和血液指标的影响

在线全文

学校读者我要写书评

暂无评论

中国饲料 2022年第15期 83-91页

作者：郭晨鑫张文杰鲁豪石坚梅莹莹邓海峰马玉辉李海杨开伦新疆农业大学动物科学学院新疆肉乳用草食动物营养重点实验室新疆乌鲁木齐830052 新疆伊犁哈萨克自治州昭苏马场新疆昭苏835602 昭苏县畜牧兽医发展中心新疆昭苏835600

为探究补喂脂肪对放牧伊犁马泌乳量、乳成分和血液指标的影响,试验选择产驹日期、泌乳期和产奶量相近、生理状况一致伊犁马母马14匹,随机分为2组,分别为精料组和脂肪组,每组7匹马,所有试验马匹均采用放牧+补饲的饲养方式。其中,精料组... 详细信息

为探究补喂脂肪对放牧伊犁马泌乳量、乳成分和血液指标的影响,试验选择产驹日期、泌乳期和产奶量相近、生理状况一致伊犁马母马14匹,随机分为2组,分别为精料组和脂肪组,每组7匹马,所有试验马匹均采用放牧+补饲的饲养方式。其中,精料组每天每匹马补喂1 kg精料补充料,脂肪组每天每匹马补喂1 kg精料补充料和400 g脂肪(均衡乳化油粉),一个月后,脂肪增加至600 g,自由饮水,进行为期2个月的试验。结果表明:(1)较精料组,脂肪组马匹泌乳量在整个试验期有显著性提高(P0.05)。(3)脂肪组马乳月桂酸、亚油酸显著高于精料组(P0.05);第20天饲喂后2 h和第60天饲喂后2 h脂肪组马匹血浆高密度脂蛋白显著高于精料组(P0.05)。综上所述,补喂脂肪可提高放牧伊犁马泌乳量、乳脂产量、乳中月桂酸和亚油酸含量以及机体对脂肪酸的吸收利用,而对马乳成分、机体抗氧化能力没有影响。

关键词：伊犁马泌乳量乳成分脂肪代谢抗氧化能力

小鼠乳腺炎模型的建立及褪黑素对小鼠乳腺炎的防治作用

在线全文

学校读者我要写书评

暂无评论

动物营养学报 2023年第11期35卷 7379-7388页

作者：仇娅琪尹海娜王生月臧长江余英英李云梦刘拓南冰禹杨开伦谭世新米热古丽·依马木新疆农业大学动物科学学院新疆肉乳用草食动物营养重点实验室乌鲁木齐830052 莎车县科学技术局莎车844700 新疆天山畜牧生物工程股份有限公司昌吉831100

本试验首先通过脂多糖(LPS)诱导建立小鼠乳腺炎模型,然后在此基础上研究褪黑素(MT)对小鼠乳腺炎的防治作用。小鼠乳腺炎模型的建立:选取14只健康的产后7~14 d的母鼠,随机分为对照组和LPS组(每组7只)。LPS组母鼠在第4对乳腺导管灌注50μL... 详细信息

本试验首先通过脂多糖(LPS)诱导建立小鼠乳腺炎模型,然后在此基础上研究褪黑素(MT)对小鼠乳腺炎的防治作用。小鼠乳腺炎模型的建立:选取14只健康的产后7~14 d的母鼠,随机分为对照组和LPS组(每组7只)。LPS组母鼠在第4对乳腺导管灌注50μL0.2 mg/mL的LPS,LPS诱导24 h后采集其血液及乳腺组织样品,测定血清及乳腺组织中促炎细胞因子含量。MT对小鼠乳腺炎的防治作用:选取56只健康的产后3~5 d的母鼠,随机分为4组,每组14只。空白对照组和模型组每日灌胃0.2 mL生理盐水,MT低、高剂量组每日分别按照1、2 mg/kg BW的剂量灌胃MT(溶于0.2 mL生理盐水)。共灌胃14 d,分别于第7、14天灌胃4 h后,从模型组以及MT低、高剂量组各挑选7只小鼠按照上述方法构建乳腺炎模型,LPS诱导24 h后采集血液及乳腺组织样品,观察乳腺组织病理学变化,并测定血清中炎性细胞因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)与白细胞介素-10(IL-10)]和抗氧化指标[超氧化物歧化酶(SOD)、谷胱甘肽氧化物酶(GSH-Px)、过氧化氢酶(CAT)、丙二醛(MDA)]的含量或活性。结果显示:1)与对照组相比,LPS组血清及乳腺组织中TNF-α、IL-6、IL-1β含量极显著升高(P<0.01),IL-10含量极显著降低(P<0.01),说明在小鼠第4对乳腺两侧的乳腺导管各灌注50μL浓度为0.2 mg/mL的LPS可以成功建立小鼠乳腺炎模型。2)乳腺组织病理组织学变化显示,MT减轻了LPS诱导的小鼠乳腺组织的损伤程度。3)灌胃7或14 d后,MT极显著降低LPS诱导的小鼠血清中TNF-α、IL-6、IL-1β的含量(P<0.01),并极显著提高IL-10的含量(P<0.01)。4)灌喂7或14 d后,MT极显著增强LPS诱导的小鼠血清中SOD、GSH-Px与CAT活性(P<0.01),并极显著降低MDA含量(P<0.01)。综上所述,MT可以抑制促炎细胞因子的分泌,促进抗炎细胞因子的分泌,增强抗氧化酶的活性,从而缓解LPS对小鼠乳腺组织造成的损伤。

关键词：褪黑素脂多糖乳腺炎炎症抗氧化

同方期刊数据库

Magnetic Property of a Spin-5/2 Trigonal Prismatic as a Model for a Molecule-based Compound Cs_4Na_7[Fe_6(OH)_3(A-ɑ-GeW_9O_(34)(OH)_3)_2]·30H_2O

在线全文

学校读者我要写书评

暂无评论

Journal of Wuhan University of Technology(Materials Science) 2015年第4期30卷 868-872页

作者：李宗宝 YAO kailun Department of Physics Tongren University Department of Physics and Wuhan High Magnetic Field Center Huazhong University of Science and Technology International Center of Materials Physics Chinese Academy of Science

The magnetic susceptibility, high field magnetization, and specific heat of spin-5/2 trigonal prismatic ＂Fe6＂ model were investigated in terms of the Heisenberg model by algebraic method. The experimental results showed that the adequate magnetization description of the Heisenberg model were provided. The magnetization curve has tour clear plateaus while the susceptibility exhibits typical anti- ferromagnetic feature. Two board peaks of the specific heat are observed at around 3 K and 15 K, while only a small sharp-peak at low field. Meanwhile, the magnetic susceptibility displays a sharp peak structure at low temperature, which is well consistent with experimental results.

关键词： magnetic field heisenberg model magnetic properties thermodynamic propertie

Epigenetic regulation of the inflammatory response in stroke

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3045-3062页

作者： Jingyi Liang Fei yang Zixiao Li Qian Li School of Basic Medical Sciences Capital Medical UniversityBeijingChina Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Laboratory for Clinical Medicine Beijing Key Laboratory of Neural Regeneration and RepairCapital Medical UniversityBeijingChina Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina National Center for Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical SciencesBeijingChina Beijing Engineering Research Center of Digital Healthcare for Neurological Diseases BeijingChina Department of Biochemistry and Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Beijing Key Laboratory of Cancer Invasion and Metastasis Research Capital Medical UniversityBeijingChina

Stroke is classified as ischemic or hemorrhagic,and there are few effective treatments for either *** mechanisms play a critical role in secondary brain injury following a stroke,which manifests as cytokine release,blood–brain barrier disruption,neuronal cell death,and ultimately behavioral *** the inflammatory response has been shown to mitigate this cascade of events in experimental stroke ***,in clinical trials of anti-inflammatory agents,longterm immunosuppression has not demonstrated significant clinical benefits for *** may be attributable to the dichotomous roles of inflammation in both tissue injury and repair,as well as the complex pathophysiologic inflammatory processes in *** acute harmful inflammatory responses or inducing a phenotypic shift from a pro-inflammatory to an anti-inflammatory state at specific time points after a stroke are alternative and promising therapeutic *** agents that can modulate inflammation requires a detailed understanding of the inflammatory processes of ***,epigenetic reprogramming plays a crucial role in modulating post-stroke inflammation and can potentially be exploited for stroke *** this review,we summarize current findings on the epigenetic regulation of the inflammatory response in stroke,focusing on key signaling pathways including nuclear factor-kappa B,Janus kinase/signal transducer and activator of transcription,and mitogen-activated protein kinase as well as inflammasome *** also discuss promising molecular targets for stroke *** evidence to date indicates that therapeutic targeting of the epigenetic regulation of inflammation can shift the balance from inflammation-induced tissue injury to repair following stroke,leading to improved post-stroke outcomes.

关键词： DNA methylation histone modification intracerebral hemorrhage ischemic stroke neuroinflammation neuroprotection non-coding RNA RNA methylation subarachnoid hemorrhage treatment