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Bacteriophages in water pollution control:Advantages and limitations

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Frontiers of Environmental Science & Engineering 2021年第5期15卷 29-43页

作者： Mengzhi Ji Zichen Liu kaili sun Zhongfang Li Xiangyu Fan Qiang Li School of Biological Science and Technology University of JinanJinan250022China College of Food and Bioengineering Hezhou UniversityHezhou542899China

Wastewater is a breeding ground for many pathogens,which may pose a threat to human health through various water transmission ***,a simple and effective method is urgently required to monitor and treat *** bacterial viruses,bacteriophages(phages)are the most widely distributed and abundant organisms in the *** to their capacity to specifically infect bacterial hosts,they have recently been used as novel tools in water pollution *** purpose of this review is to summarize and evaluate the roles of phages in monitoring pathogens,tracking pollution sources,treating pathogenic bacteria,infecting bloom-forming cyanobacteria,and controlling bulking sludge and biofilm pollution in wastewater treatment *** also discuss the limitations of phage usage in water pollution control,including phage-mediated horizontal gene transfer,the evolution of bacterial resistance,and phage concentration *** review provides an integrated outlook on the use of phages in water pollution control.

关键词： Phage Water pollution monitoring Harmful bacteria biocontrol Horizontal gene transfer Bacterial resistance

Bibliometric analysis of papers on mild cognitive impairment nursing in China

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International Journal of Nursing Sciences 2017年第1期4卷 73-79页

作者： Yating Ai kaili sun Hui Hu School of Nursing Hubei University of Chinese Medicine Wuhan China

Purpose: To supply further references by analyzing the status of research on mild cognitive impairment nursing in ***: Papers on mild cognitive impairment nursing published between 2005 and 2014 were collected from China National Knowledge Infrastructure,Wanfang Data,and China Biological Medicine database,while their publication dates,journals,and types were subjected to a bibliometric analysis using NoteExpress and ***: A total of 68 papers were collected from the selected *** number of papers on mild cognitive impairment nursing increased *** selected papers were published in 44 journals,55.88% of them were published in core journals,35.29% received funding support,35.29% were published by hospitals affiliated to colleges,47.06% were published by other local hospitals,author collaboration is 2.66,and 66.18% showed *** papers covered a wide range of topics,but were only conducted based on clinical *** 29.41% of these papers had a citation frequency of over 5,the highest citation frequency was 29,and the highest h-index was ***: Beijing and Shanghai established core author groups for mild cognitive impairment nursing *** studies should focus on the community and psychological nursing of such *** nursing interventions on different types of mild cognitive impairment should be adopted,new avenues for research should be opened,and various research methods should be introduced.

关键词： Mild cognitive impairment Nursing Bibliometric

Progresses of mycobacteriophage-based Mycobacterium tuberculosis detection

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BIOCELL 2020年第4期44卷 683-694页

作者： ZICHEN LIU SIYAO GUO MENGZHI JI kaili sun ZHONGFANG LI XIANGYU FAN School of Biological Science and Technology University of JinanJinan250022China Nanyang Technological University Food Technology Centre(NAFTEC) 637459Singapore School of Chemical and Biomedical Engineering Nanyang Technological University637459Singapore College of Food and Bioengineering Hezhou UniversityHezhou542899China

Tuberculosis(TB)remains a major cause of morbidity and mortality worldwide,particularly in developing countries.A rapid and efficient method for TB diagnosis is indispensable to check the trend of tuberculosis *** emergence of drug-resistant bacteria has increased the challenge of rapid drug resistance *** to its high specificity and sensitivity,bacteriophage-based diagnosis is intensively *** this review,we mainly described mycobacteriophage-based diagnosis in TB detection,especially two prevalent approaches:fluorescent reporter phage and phage amplified biologically assay(PhaB).The rationale of reporter phage is that phage carrying fluorescent genes can infect host bacteria *** amplified biological assay based on the principle that phages can infect the live Mycobacterium tuberculosis in the specimen under suitable conditions and produce *** phage-based diagnostic methods,such as a combination of the amplified biologically assay and nucleic acid amplification or lateral flow assays,are also actively *** review will help us improve the understanding of mycobacteriophages in TB detection and better promote the development of the rapid diagnosis of ***.

关键词： Mycobacteriophage Tuberculosis Diagnosis Reporter phage Phage amplified biologically assay

Ultrafast Laser-Induced Excellent Thermoelectric Performance of PEDOT:PSS Films

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Energy & Environmental Materials 2024年第3期7卷 425-431页

作者： Xuewen Wang Yuzhe Feng kaili sun Nianyao Chai Bo Mai Sheng Li Xiangyu Chen Wenyu Zhao Qingjie Zhang State Key Laboratory of Advanced Technology for Materials Synthesis and Processing International School of Materials Science and EngineeringWuhan University of TechnologyNo.122Luoshi Rd.Wuhan 430070China Foshan Xianhu Laboratory of the Advanced Energy Science and Technology Guangdong Laboratory No.1Yangming Rd.Foshan 528200China

Because poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate)(PEDOT:PSS)is water processable,thermally stable,and highly conductive,PEDOT:PSS and its composites have been considered to be one of the most promising flexible thermoelectric ***,the PEDOT:PSS film prepared from its commercial aqueous dispersion usually has very low conductivity,thus cannot be directly utilized for TE ***,a simple environmental friendly strategy via femtosecond laser irradiation without any chemical dopants and treatments was *** optimal conditions,the electrical conductivity of the treated film is increased to 803.1 S cm^(-1)from 1.2 S cm^(-1)around three order of magnitude higher,and the power factor is improved to 19.0μW m^(-1)K^(-2),which is enhanced more than 200 *** mechanism for such remarkable enhancement was attributed to the transition of the PEDOT chains from a coil to a linear or expanded coil conformation,reduction of the interplanar stacking distance,and the removal of insulating PSS with increasing the oxidation level of PEDOT,facilitating the charge *** work presents an effective route for fabricating high-performance flexible conductive polymer films and wearable thermoelectric devices.

关键词： electrical conductivity PEDOT:PSS thermoelectric film ultrafast laser irradiation

Static analysis of tympanic membrane in aero-otitis media by three-dimensional model of the middle ear

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Theoretical & Applied Mechanics Letters 2022年第2期12卷 111-117页

作者： kaili sun Xu Bie Zhixing Feng Shen Yu Xiuzhen sun Jizhe Wang Yingxi Liu Lina Peng Zhaoxu Yao Department of Otolaryngology-Head and Neck Surgery The 2nd Affiliated Hospital of Dalian Medical UniversityDalian 116027China Department of Otolaryngology-Head and Neck Surgery Handan Central HospitalHandan 056001China Department of Engineering Mechanics Dalian University of TechnologyDalian 116024China

The three-dimensional(3D)model of the middle ear is of great significance to the research of middle ear related *** particular focus of this work is to simulate the impact of aircraft altitude and speed changes on the tympanic membrane(TM)during the descent phase,so as to analyze the pathogenesis of aero-otitis media and the mechanical response characteristics of TM under static *** simulations showed that the stress and strain of TM increase as the altitude difference and speed of the aircraft increase,and the maximum stress and strain areas are consistent with the clinical observation of TM ***,among many prevention and treatment measures of aero-otitis media,it is a therapeutic method to directly balance the pressure difference between the inner and outer TM.

关键词： Aero-otitis media The middle ear Numerical simulation Statics calculation Tympanostomy tube placement

Novel defined N7-methylguanosine modification-related lncRNAs for predicting the prognosis of laryngeal squamous cell carcinoma

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BIOCELL 2023年第9期47卷 1965-1975页

作者： ZHAOXU YAO HAIBIN MA LIN LIU QIAN ZHAO LONGCHAO QIN XUEYAN REN CHUANJUN WU kaili sun Department of Otolaryngology Handan Central HospitalHandan056001China

Objective:Through integrated bioinformatics analysis,the goal of this work was to find new,characterised N7-methylguanosine modification-related long non-coding RNAs(m7G-lncRNAs)that might be used to predict the prognosis of laryngeal squamous cell carcinoma(LSCC).Methods:The clinical data and LSCC gene expression data for the current investigation were initially retrieved from the TCGA database&***,using co-expression analysis of m7G-associated mRNAs&lncRNAs&differential expression analysis(DEA)among LSCC&normal sample categories,we discovered lncRNAs that were connected to *** prognosis prediction model was built for the training category using univariate&multivariate COX regression&LASSO regression analyses,&the model’s efficacy was checked against the test category *** addition,we conducted DEA of prognostic m7G-lncRNAs among LSCC&normal sample categories&compiled a list of co-expression networks&the structure of prognosis *** compare the prognoses for individuals with LSCC in the high-&low-risk categories in the prognosis prediction model,survival and risk assessments were also carried ***,we created a nomogram to accurately forecast the outcomes of LSCC patients&created receiver operating characteristic(ROC)curves to assess the prognosis prediction model’s predictive ***:Using co-expression network analysis&differential expression analysis,we discovered 774 m7G-lncRNAs and 551 DEm7G-lncRNAs,*** then constructed a prognosis prediction model for six m7G-lncRNAs(FLG−AS1,RHOA−IT1,AC020913.3,AC027307.2,AC010973.2 and AC010789.1),identified 32 DEPm7G-lncRNAs,analyzed the correlation between 32 DEPm7G-lncRNAs and 13 DEPm7G-mRNAs,and performed survival analyses and risk analyses of the prognosis prediction model to assess the prognostic performance of LSCC *** displaying ROC curves and a nomogram,we finally checked the prognosis prediction model's ***:By creating novel predictive

关键词： N7-methylguanosine modification Prognostic lncRNAs signatures Prognosis prediction model Laryngeal squamous cell carcinoma

1D quasi-bound states in the continuum with large operation bandwidth in theω~k space for nonlinear optical applications

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Photonics Research 2022年第7期10卷 1575-1581页

作者： kaili sun HUI JIANG DMITRY ABYKOV VIEN VAN URIEL LEVY YANGJIAN CAI ZHANGHUA HAN Shandong Provincial Key Laboratory of Optics and Photonic Devices Center of Light Manipulation and ApplicationsSchool of Physics and ElectronicsShandong Normal UniversityJinan 250358China Image Processing Systems Institute—Branch of the Federal Scientific Research Centre“Crystallography and Photonics”of Russian Academy of Sciences Samara 443001Russia Department of Electrical and Computer Engineering University of AlbertaEdmontonAlberta T6G 2V4Canada Department of Applied Physics and Center for Nanoscience and NanotechnologyThe Hebrew University of JerusalemJerusalemIsrael

The phenomenon of bound state in the continuum(BIC)with an infinite quality factor and lifetime has emerged in recent years in photonics as a new tool to manipulate light-matter ***,most of the investigated structures only support BIC resonances at very few discrete points in theω~k *** when the BIC is switched to a quasi-BIC(QBIC)resonance through perturbation,its frequency will still be located within a narrow spectral band close to that of the original BIC,restricting their applications in many fields where random or multiple input frequencies beyond the narrow band are *** this work,we demonstrate that a new set of QBIC resonances can be supported by using a special binary grating consisting of two alternatingly aligned ridge arrays with the same period and zero-approaching ridge width difference on a slab *** QBIC resonances are distributed continuously over a broad band along a line in theω~k space and can thus be considered as 1 D *** the Q factors generally affected by the ridge difference,it is now possible to arbitrarily choose any frequencies on the dispersion line to achieve significantly enhanced light-matter interactions,facilitating many applications where multiple input wavelengths are required;e.g.,sum or difference frequency generations in nonlinear optics.

关键词： quasi nonlinear narrow

微纳光学结构与太赫兹辐射产生技术的研究进展

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光学学报 2021年第8期41卷 258-270页

作者：韩张华孙开礼蔡阳健山东师范大学光场调控及应用中心山东济南250358 山东省光学与光子器件技术重点实验室山东济南250358 山东省光场调控工程技术中心山东济南250358

太赫兹(THz)技术在基础研究与产业应用中具有重要研究意义,但其广泛应用仍受限于高效、紧凑的THz源,特别是0.5~2.0 THz波段。目前,人们已经采用了多种技术产生THz辐射,基于光学的方法是其中最重要的手段。首先,针对THz脉冲波及连续波,... 详细信息

太赫兹(THz)技术在基础研究与产业应用中具有重要研究意义,但其广泛应用仍受限于高效、紧凑的THz源,特别是0.5~2.0 THz波段。目前,人们已经采用了多种技术产生THz辐射,基于光学的方法是其中最重要的手段。首先,针对THz脉冲波及连续波,基于光电导效应及非线性光学差频的THz辐射产生机理,总结了近年来微纳光学结构在提高泵浦光至THz转换效率上的应用。然后,分析了金属纳米光天线通过增强泵浦光局域电场提高THz辐射效率和将金属纳米光天线作为THz辐射源两种增强情况。最后,展望了其他类型的光学微纳结构,尤其是全介质光学天线支持的米氏谐振、无辐射模式以及连续域中束缚态等新颖物理现象在THz辐射产生中的增强作用。

关键词：光学器件太赫兹辐射光学纳米天线局域场增强光电导天线光整流

Adsorption Properties of Calcined Modified Sepiolite on SO4^2- and Cl^-

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Journal of Wuhan University of Technology(Materials Science) 2020年第1期35卷 32-41页

作者：孙凯利王彩辉 ZHANG Guanglei NIU Han FU Shifeng WU Yueze YANG Jinhui State Key Laboratory of Mechanical Behavior and System Safety of Traffic Engineering Structures Shijiazhuang Tiedao UniversityShijiazhuang 050043China Hebei Institute of Technology Co. Ltd.ShiJiaZhuang 050021China

Three different kinds of sepiolite(Type A, Type B and Sepiolite fiber) were processed by calcination and analyzed by thermogravimetric analysis(TG), X-ray diffraction diffractometer(XRD), scanning electron microscopy(SEM), BET(specific surface area from N2 adsorption isotherms), mercury intrusion porosimetry(MIP), and infrared spectroscopic analysis(IR), respectively. The results show that the adsorption performance of sepiolite can be changed by calcination and environment temperatures, especially for calcination. The adsorption capacity of sepiolite fiber is bigger than that of Type A and B, and adsorption capacity of each sepiolite to sulfate is smaller than that of the chloride ions. Especially, the maximum value for adsorption of the sepiolite fibers, calcined at 600 ℃ and water bath at 60 ℃, to chlorine ion and sulfate are 5.95 and 5.71 mg/g, respectively(mg/g : the ions quantity adsorbed by a unit of sepiolite weight). The minimum adsorption of calcined sepiolite fiber to sulfate ions increased from 5.02 to 5.55 mg/g. While microstructure analysis of sepiolite by TG indicated that its structure was, for temperature not exceeding 700 ℃, was not changed significantly. Sepiolite has a porous structure, especially for sepiolite fiber, which can be observed by SEM. BET indicates that sepiolite fiber has a larger pore volume than others and this can be increased by calcination. IR shows that the adsorption of sepiolite to Cl-and SO42- belongs to physical absorption, instead of chemisorption.

关键词： adsorption chloridion sepiolite sulfate ion temperature