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Optimizing near-carbon-free nuclear energy systems:advances in reactor operation digital twin through hybrid machine learning algorithms for parameter identification and state estimation

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Nuclear Science and Techniques 2024年第8期35卷 177-203页

作者： li‑Zhan Hong He‑lin Gong Hong‑Jun Ji jia‑liang Lu Han li Qing li Paris Elite Institute of Technology Shanghai Jiao Tong UniversityShanghai 200240China Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of ChinaChengdu 610041China

Accurate and efficient online parameter identification and state estimation are crucial for leveraging digital twin simulations to optimize the operation of near-carbon-free nuclear energy *** previous studies,we developed a reactor operation digital twin(RODT).However,non-differentiabilities and discontinuities arise when employing machine learning-based surrogate forward models,challenging traditional gradient-based inverse methods and their *** study investigated deterministic and metaheuristic algorithms and developed hybrid algorithms to address these *** efficient modular RODT software framework that incorporates these methods into its post-evaluation module is presented for comprehensive *** methods were rigorously assessed based on convergence profiles,stability with respect to noise,and computational *** numerical results show that the hybrid KNNLHS algorithm excels in real-time online applications,balancing accuracy and efficiency with a prediction error rate of only 1%and processing times of less than 0.1 ***,algorithms such as FSA,DE,and ADE,although slightly slower(approximately 1 s),demonstrated higher accuracy with a 0.3%relative L_2 error,which advances RODT methodologies to harness machine learning and system modeling for improved reactor monitoring,systematic diagnosis of off-normal events,and lifetime management *** developed modular software and novel optimization methods presented offer pathways to realize the full potential of RODT for transforming energy engineering practices.

关键词： Parameter identification State estimation Reactor operation digital twin Reduced order model Inverse problem

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Equipment damage measurement method of wartime based on FCE-PCA-RF

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Journal of Systems Engineering and Electronics 2024年第3期35卷 707-719页

作者： li Mingyu GAO Lu XU Hongwei li kai HUANG Yisong Shijiazhuang Campus of Army Engineering University Shijiazhuang 050003China Shijiazhuang Campus of Army Infantry Academy Shijiazhuang 050227China

As the“engine”of equipment continuous operation and repeated operation, equipment maintenance support plays a more prominent role in the confrontation of symmetrical combat systems. As the basis and guide for the planning and implementation of equipment maintenance tasks, the equipment damage measurement is an important guarantee for the effective implementation of maintenance support. Firstly,this article comprehensively analyses the influence factors to damage measurement from the enemy’s attributes, our attributes and the battlefield environment starting from the basic problem of wartime equipment damage measurement. Secondly, this article determines the key factors based on fuzzy comprehensive evaluation(FCE) and performed principal component analysis (PCA) on the key factors. Finally, the principal components representing more than 85%of the data features are taken as the input and the equipment damage quantity is taken as the output. The data are trained and tested by artificial neural network (ANN) and random forest (RF). In a word, FCE-PCA-RF can be used as a reference for the research of equipment damage estimation in wartime.

关键词： wartime equipment damage fuzzy comprehensive evaluation(FCE) principal component analysis(PCA) artificial neural network(ANN) random forest(RF)

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Application of GNSS-PPP on Dynamic Deformation Monitoring of Offshore Platforms

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China Ocean Engineering 2024年第2期38卷 352-361页

作者： YU li-na XIONG Kuan GAO Xi-feng li Zhi FAN li-long ZHANG kai Institute of Ocean Energy and Intelligent Construction Tianjin University of TechnologyTianjin 300384China China Railway Construction Bridge Engineering Bureau Group Co.LTD Tianjin 300300China School of Civil Engineering Tianjin UniversityTianjin 300072China Department of Land Surveying and Geo-Informatics The Hong Kong Polytechnic UniversityHong KongChina State Key Laboratory of Precision Blasting Jianghan UniversityWuhan 430056China

The real-time dynamic deformation monitoring of offshore platforms under environmental excitation is crucial to their safe *** Global Navigation Satellite System-Precise Point Positioning(GNSS-PPP)has been considered for this purpose,its monitoring accuracy is relatively ***,the influence of background noise on the dynamic monitoring accuracy of GNSS-PPP remains ***,it is imperative to further validate the feasibility of GNSS-PPP for deformation monitoring of offshore *** address these concerns,vibration table tests with different amplitudes and frequencies are *** results demonstrate that GNSS-PPP can effectively monitor horizontal vibration displacement as low as±30 mm,which is consistent with ***,the spectral characteristic of background noise in GNSS-PPP is similar to that of GNSS-RTK(Real Time Kinematic).Building on this observation,an improved Complete Ensemble Empirical Mode Decomposition with Adaptive Noise(CEEMDAN)has been proposed to de-noise the data and enhance the dynamic monitoring accuracy of *** monitoring application research is also undertaken,successfully extracting and analyzing the dynamic deformation of an offshore platform structure under environmental excitation using GNSS-PPP monitoring in conjunction with improved CEEMDAN *** comparing the de-noised dynamic deformation trajectories of the offshore platform during different periods,it is observed that the platform exhibits reversible alternating vibration responses under environmental excitation,with more pronounced displacement deformation in the direction of load *** research results confirm the feasibility and potential of GNSS-PPP for dynamic deformation monitoring of offshore platforms.

关键词： GNSS-PPP offshore platform dynamic deformation monitoring improved CEEMDAN de-noising

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Spatial transcriptomics:recent developments and insights in respiratory research

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Military Medical Research 2024年第3期11卷 430-448页

作者： Wen-jia Wang liu-Xi Chu li-Yong He Ming-Jing Zhang kai-Tong Dang Chen Gao Qin-Yu Ge Zhou-Guang Wang Xiang-Wei Zhao State Key Laboratory of Bioelectronics School of Biological Science and Medical EngineeringSoutheast UniversityNanjing 210096China Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine Vision and Brain Health)School of Pharmaceutical SciencesWenzhou Medical UniversityWenzhou 325035ZhejiangChina Orthopaedic Bioengineering Research Group Division of Surgery and Interventional ScienceUniversity College LondonLondon HA74LPUK

The respiratory system's complex cellular heterogeneity presents unique challenges to researchers in this *** bulk RNA sequencing and single-cell RNA sequencing(scRNA-seq)have provided insights into cell types and heterogeneity in the respiratory system,the relevant specific spatial localization and cellular interactions have not been clearly *** transcriptomics(ST)has filled this gap and has been widely used in respiratory *** review focuses on the latest iterative technology of ST in recent years,summarizing how ST can be applied to the physiological and pathological processes of the respiratory system,with emphasis on the ***,the current challenges and potential development directions are proposed,including high-throughput full-length transcriptome,integration of multi-omics,temporal and spatial omics,bioinformatics analysis,*** viewpoints are expected to advance the study of systematic mechanisms,including respiratory studies.

关键词： Spatial transcriptomics Lung Tumor Spatial multi-omics

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Synthesis,Characterization of Polyethylene Ionomers and Their Antibacterial Properties

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Chinese Journal of Polymer Science 2024年第8期42卷 1077-1084页

作者： jia-jia Wu Fei Wang Peng-Qi Wan li Pan Chun-Sheng Xiao Zhe Ma Yue-Sheng li Tianjin Key Lab Composite&Functional Materials School of Materials Science and EngineeringTianjin UniversityTianjin 300350China Key Lab Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China

Owing to its high production volume and wide range of application s,polyethylene has gained a great deal of attention,but its low surface energy and non-polar nature have limited its application in some important *** this study,ethylene/11-iodo-1-undecene copolymers were prepared and used as the intermediates to afford a series of imidazolium-based ionomers bearing methanesulfonate(CH_(3)SO_(3)^(-)),trifluoromethanesulfonate(CF_(3)SO_(3)^(-)),or bis(trifluoromethane)sulfonimide(Tf_(2)N^(-))*** tensile test results showed that the stress-at-break(7.8-25.6 MPa)and the elongation-at-break(445%-847%)of the ionomers could be adjusted by changing the counterion species and the ionic group *** importantly,the ionomers exhibited marvelous antibacterial activities against Staphylococcus aureus(***)and Escherichia coli(***).The ionomers bearing Tf_(2)N^(-)exhibited antibacterial activities>99%against both *** and *** when ionic content reached 9.1%.The imidazolium-based ionomers prepared in this work demonstrated excellent comprehensive properties,especially highefficient and broad-spectrum antibacterial ability,exhibiting the potential fo r the application as the antibacterial materials in packaging,medical,and other fields.

关键词： Polyethylene Ionomer Polymerization catalysis Imidazolium Antibacterial material

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Optical and electrical anisotropy regulation engineering of low-dimensional materials toward polarized detection and imaging applications

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Rare Metals 2024年第7期43卷 2968-2993页

作者： jian-Bin Zhang Nan Zhou li-Hui Zhang Cong-Hui Shang jia-Xuan li Yi Zhao Guo-Hui jia Ru-Sen Yang Hua Xu Xiao-Bo li Shaanxi Joint Key Laboratory of Graphene Shaanxi Key Laboratory of High-Orbits-Electron Materials and Protection Technology for AerospaceShaanxi Joint Key Laboratory of GrapheneSchool of Advanced Materials and NanotechnologyXidian UniversityXi'an710126China Guangzhou Institute of Technology Xidian UniversityGuangzhou 710068China Xi'an Thermal Power Research Institute Co. LtdXi'an 710054China Key Laboratory of Applied Surface and Colloid Chemistry Ministry of EducationShaanxi Key Laboratory for Advanced Energy DevicesShaanxi Engineering Lab for Advanced Energy TechnologySchool of Materials Science and EngineeringShaanxi Normal UniversityXi'an Xi'an 710119China

Polarized-sensitive image sensors are a kind of photodetector with great development potential due to their enhanced ability to detect and identify the target objects from the aspect of spatial,spectral and polarized ***,low-dimensional anisotropic materials with inherent anisotropic properties,ultrathin thickness,tunable bandgap and feasible integration with complementary metal oxide semiconductor(CMOS)fabrication processes have attracted great interest for their facilitation of polarized photodetector devices *** the polarized detection performance of low-dimensional materials to satisfy realistic needs stimulates the exploration of modulation of anisotropic *** this review,we comprehensively introduce the latest research progress in modulating the optical and optoelectronic anisotropy characteristics of low-dimensional *** strategy of anisotropy regulation through crystal structure engineering and coupling system is discussed ***,the latest progress in image recognition applications using anisotropic low-dimensional materials is reviewed in ***,we summarize the challenge and propose future opportunities in the practical application of polarized-sensitive imaging photodetectors based on low-dimensional anisotropic materials.

关键词： Anisotropy Polarized detection Image recognition Low-dimensional materials

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Novel heterozygous USH1C mutation impacts hair cell mechanotransduction and causes progressive hearing loss

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Science Bulletin 2024年第2期69卷 167-172页

作者： Yanyan jia Gaogan jia Luo Guo Nan Song Yu-Meng Wang Luoying jiang Yilai Shu Yan Chen Shujia Zhu Huawei li Wenyan li ENT Institute and Otorhinolaryngology Department of Eye&ENT Hospital State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain ScienceFudan UniversityShanghai 200031China Institutes of Biomedical Sciences Fudan UniversityShanghai 200032China NHC Key Laboratory of Hearing Medicine(Fudan University) Shanghai 200031China The Institutes of Brain Science and the Collaborative Innovation Center for Brain Science Fudan UniversityShanghai 200032China Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology Shanghai 201210China Institute of Neuroscience State Key Laboratory of NeuroscienceCAS Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai 200031China Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular MedicineXinhua Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghai 200092China

Hearing loss is one of the most common sensory disorders worldwide,affecting approximately 466 million people,including 34 million children[1].Genetic mutations accounts for approximately 60%of inherited hearing loss cases[2,3].These genetic changes result in a wide variety of clinical manifestations,ranging from nonsyndromic hearing loss(NSHL)to over 400 syndromes involving hearing loss and from mild adult-onset hearing loss to profound congenital deafness,covering the entire spectrum of Mendelian inheritance.

关键词： mec hearing approximate

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Interconnection of cellular autophagy and endosomal vesicle trafficking and its role in hepatitis B virus replication and release

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Virologica Sinica 2024年第1期39卷 24-30页

作者： jia li Yong lin Xueyu Wang Mengji Lu Institute for Virology University Hospital EssenUniversity of Duisburg-EssenEssen45122Germany Key Laboratory of Molecular Biology of Infectious Diseases(Chinese Ministry of Education) Chongqing Medical UniversityChongqing400016China The Key Laboratory for Diagnosis and Treatment of Infectious Diseases The First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou310000China

Hepatitis B virus(HBV)produces and releases various particle types,including complete virions,subviral particles with envelope proteins,and naked *** studies demonstrate that HBV exploits distinct intracellular membrane trafficking pathways,including the endosomal vesicle trafficking and autophagy pathway,to assemble and release viral and subviral ***,we summarize the findings about the distinct roles of autophagy and endosomal membrane trafficking and the interaction of both pathways in HBV replication,assembly,and release.

关键词： Amphisome Autophagy Endosomal vesicle Hepatitis B virus(HBV)

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Rapid chemical recycling of waste polyester plastics catalyzed by recyclable catalyst

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Green Chemical Engineering 2024年第2期5卷 257-265页

作者： Yu-Ji Luo jia-Yin Sun Zhi li School of Physical Science and Technology ShanghaiTech UniversityShanghai201210China

Waste plastics are serious environmental threats due to their low degradability and low recycling *** and efficient waste plastics recycling technologies are urgently demanded for a sustainable ***,we report a rapid,closed-loop,and streamlined process to convert polyesters such as poly(ethylene terephthalate)(PET)back to its purified *** trifluoromethanesulfonic acid or metal triflates as the recyclable catalyst,polyesters such as PET can be completely depolymerized by simple carboxylic acids within 1 *** coupling this acidolysis with a subsequent hydrogenolysis process,the consumed carboxylic acid was recovered and the closed-loop of PET depolymerization could be *** catalysts and depolymerization agents are fully recycled while only PET and hydrogen are consumed.

关键词： Chemical recycling Waste polyester plastics Acidolysis Recyclable catalyst

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Adsorption of tetrodotoxin by flexible shape-memory polymers synthesized from silica-stabilized Pickering high internal phase emulsion

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2021年第10期22卷 805-818页

作者： Hong-xiang OU Chen-xia GONG Hong-lai XUE Dong-sheng ZHOU kai-jia li Shu-cheng liU School of Environmental and Safety Engineering Changzhou UniversityChangzhou 213164China Institute of Public Safety and Emergency Management Changzhou UniversityChangzhou 213164China School of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China

Flexible shape-memory polymers were synthesized by Pickering high internal phase emulsion(HIPE)polymerization and used to adsorb and separate tetrodotoxin(TTX)from an aqueous ***_(2)nanoparticles were used to stabilize the Pickering oil-in-water(O/W)*** introduced imidazolium-modified bromobutyl rubber(IBR)with excellent mechanical properties and high viscosity into the emulsion system as the shape-memory *** properties,such as shape memory and morphology,were characterized by various methods,and batches of static adsorption experiments were conducted to analyze the adsorption performance of SiO_(2)@IBR on *** characterization revealed that the SiO_(2)@IBR had a porous structure and good shape ***,the combination of SiO_(2)particles and IBR prevented shedding of SiO_(2)and enhanced the mechanical and adsorption properties of SiO_(2)@*** results of the adsorption experiments indicated that the SiO_(2)@IBR had good adsorption of *** the Langmuir and Freundlich models fitted the isothermal adsorption experiment *** TTX adsorption capacity of SiO_(2)@IBR was about 290.44 mg/g at 308 *** fitting results of the pseudo-first-order and pseudosecond-order kinetic models showed that the adsorption process involved both chemical bonding and physical *** 10 adsorption and desorption experiments,the adsorption capacity of SiO_(2)@IBR decreased less than 0.03%,indicating that it had good adsorption and regeneration performance.

关键词： Tetrodotoxin(TTX) SiO_(2) Imidazolium-modified bromobutyl rubber(IBR) Pickering high internal phase emulsion(HIPE) Adsorption

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