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Science China(Technological Sciences) 2024年第6期67卷 1893-1906页

作者： AN kai WANG ZhenGuo huaNG wei Hypersonic Technology Laboratory National University of Defense TechnologyChangsha410073China

We propose an adaptive learning-based optimal control scheme for height-velocity control models considering model uncertainties and external disturbances of hypersonic winged-cone *** longitudinal nonlinear model is first established and transformed into the control-oriented error equations,and the control scheme is organized by a steady-compensation *** overcome and eliminate the impact of model uncertainties and external disturbances,an adaptive radial basis function neural network(RBFNN)is designed by a q-gradient *** the height-velocity error system with estimated uncertainties into account,the adaptive learning-based optimal tracking control(ALOTC)scheme is proposed by combining the critic-only adaptive dynamic programming(ADP)framework and parameter optimization of system settling ***,a novel weight update law is proposed to satisfy the online iteration requirements,and the algorithm convergence and closedloop stability are discussed by the Lyapunov ***,four simulation cases are provided to prove the effectiveness,accuracy,and robustness of the proposed scheme for the hypersonic longitudinal control system.

关键词： optimal tracking control adaptive dynamic programming RBFNN hypersonic vehicle

Correlation between longitudinal crack occurrence and mold heat transfer in continuous casting based on process data mining

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Journal of Iron and Steel Research International 2024年第5期31卷 1139-1152页

作者： Zhi-qiang Peng Zi-bing Hou kai Yi Kun-hui Guo Dong-wei Guo Guang-hua Wen College of Materials Science and Engineering Chongqing UniversityChongqing400044China Chongqing Key Laboratory of Vanadium-Titanium Metallurgy and New Materials Chongqing UniversityChongqing400044China

The correlation between the longitudinal crack occurrence and integrated heat transfer of the mold with data mining methods was ***,three kinds of support vector machine models based on principal component analysis with different input features were established to explore the effect of integrated heat transfer on the accuracy of the prediction model for the longitudinal *** results show that the accuracy was improved while features including mean and standard deviation of integrated heat transfer were ***,the difference in integrated heat transfer between defect and normal samples under the same process parameters was quantitatively *** with normal samples,the temperature difference of cooling water for defect samples decreased by 0.65%,and the temperature difference fluctuation increased by 31.1%.Finally,the literature data were used to provide support for the quantitative correlation according to defect formation mechanism.A new criterion for the prediction of longitudinal crack and a discovering method for correlation between product quality and process parameters in the manufacturing industry have been provided.

关键词： Continuous casting slab Longitudinal surface crack Heat transfer Data mining Quantitative correlation

Strong light–matter interactions based on excitons and the abnormal all-dielectric anapole mode with both large field enhancement and low loss

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Photonics Research 2024年第4期12卷 854-864页

作者： YAN-HUI DENG YU-wei LU HOU-JIAO ZHANG ZHONG-HONG SHI ZHANG-kai ZHOU XUE-hua WANG State Key Laboratory of Optoelectronic Materials and Technologies School of PhysicsSun Yat-sen UniversityGuangzhou 510275China Quantum Science Center of Guangdong–Hong Kong–Macao Greater Bay Area(Guangdong) Shenzhen 518045China

The room temperature strong coupling between the photonic modes of micro/nanocavities and quantum emitters(QEs) can bring about promising advantages for fundamental and applied *** the electric fields(EFs) by using plasmonic modes and reducing their losses by applying dielectric nanocavities are widely employed approaches to achieve room temperature strong ***,ideal photonic modes with both large EFs and low loss have been ***,we propose the abnormal anapole mode (AAM),showing both a strong EF enhancement of~70-fold (comparable to plasmonic modes) and a low loss of 34 meV,which is much smaller than previous records of isolated all-dielectric *** realizing strong coupling,we further show that by replacing the normal anapole mode with the AAM,the lasing threshold of the AAM-coupled QEs can be reduced by one order of magnitude,implying a vital step toward on-chip integration of nanophotonic devices.

关键词： dielectric mode coupling

Immunoproteomics of membrane proteins of Shigella flexneri 2a 2457T

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World Journal of Gastroenterology 2005年第43期11卷 6880-6883页

作者： Tian-Yi Ying Jun-Jun Wang Heng-Liang Wang Er-Ling Feng kai-hua wei Liu-Yu huang Pei-Tang huang Cui-Fen huang Beijing Institute of Biotechnology State Key Lab of Pathogen and Biosecurity Beijing 100071 China Beijing Institute of Pharmaceutical Chemistry Beijing 102205 China

AIM： To screen the immunogenic membrane proteins of Shigella Aexneri 2a 2457T. METHODS： The routine two-dimensional polyacrylamide gel electrophoresis （2-DE） and Western blotting were combined to screen immunogenic proteins of S. Aexneri 2a 2457T. Serum was gained from rabbits immunized with the same bacteria. Immunogenic spots were cut out from the polyacrylamide gel and digested by trypsin in-gel. Matrix-assisted laser desorption/ionization time of flight-mass spectrometry （MALDI-TOF-MS） was performed to determine the molecular weight of peptides. Electrospray ionization （ESI-MS/MS） was performed to determine the sequences of the interesting peptides. RESULTS： A total of 20 spots were successfully identified from Coomassie brilliant blue stained gels representing 13 protein entries, 5 known antigens and 8 novel antigens. A hypothetical protein （YaeT） was detected, which might be a candidate target of vaccine. CONCLUSION： Membrane proteins of S. flexneri 2a 2457T were successfully observed by 2-DE. Several known and novel antigens were identified by mass spectrum.

关键词： Shigella flexneri 2a 2457T Immunoproteomics Membrane proteins

Process,Material,and Regulatory Considerations for 3D Printed Medical Devices and Tissue Constructs

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Engineering 2024年第5期36卷 146-166页

作者： wei Long Ng Jia An Chee kai Chua Singapore Centre for 3D Printing(SC3DP) School of Mechanical and Aerospace EngineeringNanyang Technological UniversitySingapore 639798Singapore Centre for Healthcare Education Entrepreneurship and Research@SUTD(CHEERS)Singapore University of Technology and DesignSingapore 487372Singapore

Three-dimensional(3D)printing is a highly automated platform that facilitates material deposition in a layer-by-layer approach to fabricate pre-defined 3D complex structures on *** is a highly promising technique for the fabrication of personalized medical devices or even patient-specific tissue *** type of 3D printing technique has its unique advantages and limitations,and the selection of a suitable 3D printing technique is highly dependent on its intended *** this review paper,we present and highlight some of the critical processes(printing parameters,build orientation,build location,and support structures),material(batch-to-batch consistency,recycling,protein adsorption,biocompatibility,and degradation properties),and regulatory considerations(sterility and mechanical properties)for 3D printing of personalized medical *** goal of this review paper is to provide the readers with a good understanding of the various key considerations(process,material,and regulatory)in 3D printing,which are critical for the fabrication of improved patient-specific 3D printed medical devices and tissue constructs.

关键词： 3D printing Bioprinting Biofabrication Medical devices Tissue constructs

Mechanical performance of 22SiMn2TiB steel welded with lowtransformation- temperature filler wire and stainless steel filler wire

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Journal of Iron and Steel Research International 2024年第4期31卷 967-981页

作者： Zi-dong Lin kai-jie Song Zhen Sun Zi-qian Zhu Xue-feng Zhao Constantinos Goulas wei Ya Xing-hua Yu School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401120China Department of Design Production and Management Faculty of Engineering Technology.University of TwenteEnschede 7500 AETheNetherlands Rotterdam Additive Manufacture Fieldlab(RAMLAB) Rotterdam 3089 JWTheNetherlands

TX-80 low-transformation-temperature(LTT)welding wire was used to replace the traditional ER 307Si welding wire to realize the connection of 22SiMn2TiB armor steel in manual overlay *** previously existing issues,such as welding cracks,large welding deformation,and severe welding residual stress,were solved to ensure good strength and ductility *** particular,with the same welding conditions,TX-80 LTT wire eliminates welding *** reduces the welding deformation no matter the base pretreatment of pre-setting angle or no pre-setting *** comparison,it was found that the microstructure at the TX-80 weld is mainly composed of martensite and a small amount of retained *** contrast,the microstructure of the ER 307Si weld consists of a large amount of austenite and a small amount of skeleton-like *** variation trend of residual stress and microhardness from the weld to the base were investigated and compared with the mechanical properties of base *** TX-80 and the ER 307Si tensile samples elongation is 6.76%and 6.01%,while the ultimate tensile strengths are 877 and 667 MPa,*** average impact toughness at room temperature of the ER 307Si weld is 143.9 J/cm^(2),much higher than that of the TX-80 weld,which is only 36.7 J/cm^(2).The relationship between impact and tensile properties with microstructure species and distribution was *** addition,the fracture surface of the tensile and the impact samples was observed and *** dimples,fewer pores,larger radiation zone,and shear lips of TX-80 samples indicate better tensile ductility and worse impact toughness than those of ER 307Si weld.

关键词： Low-transformation-temperature material 22SiMn2TiB steel Welding deformation Residual stress Martensitic transformation Mechanical property

USP45 acts as an oncogene to regulate the proliferation of esophageal cancer cells

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Genes & Diseases 2024年第5期11卷 44-47页

作者： kai Li Qian Wang hua Bian Zhang Zhongjing College of Chinese Medicine Henan Key Laboratory of Zhang Zhongjing Formulae and Herbs for ImmunoregulationNanyang Institute of TechnologyNanyangHenan 473004China College of Orthopaedics and Traumatology Henan University of Chinese MedicineZhengzhouHenan 450046China

Deubiquitinases(DUBs)are a class of enzymes that are able to reverse the process of ubiquitination.1 Extensive research has revealed that there are more than 100 DUBs found in humans,which are classified into seven main families:ubiquitin-specific proteases(USPs),ubiquitin carboxyl-terminal hydrolases,the Machado-Joseph disease domain superfamily,the otubain/ovarian tumor-domain containing proteins,the ZUFSP(Zinc finger with UFM1-specific peptidase domain protein)family,the JAB1/MPN/MOV34 proteases,and the novel motif interacting with ubiquitin-containing DUB *** DUBs are cysteine proteases,except the JAB1/MPN/MOV34 proteases,which are Zn^(2+) metalloproteases.

关键词： esophageal cancer Zinc

How to Construct a Lower Risk FOF Based on Correlation Network? The Method of Principal Component Risk Parity Asset Allocation

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Journal of Systems Science & Complexity 2024年第3期37卷 1052-1079页

作者： BAI wei ZHANG Junting LIU Haifei LIU kai School of Management and Engineering Nanjing UniversityNanjing 210093China Postdoctoral Workstation of Bank of Jiangsu Co. LtdNanjing 210006China College of Finance Nanjing Agricultural UniversityNanjing 210095China University of Prince Edward Island 550 University AveCharlottetownPE C1A4P3Canada

In order to build a low-risk Fund of Funds(FOF), from the perspective of correlation, the principal component factor is used to improve the traditional risk parity model. Principal component analysis is used to decompose the underlying assets and generate unrelated principal component factors,and then the authors can construct a principal component risk parity portfolio. The proposed empirical results based on China’s mutual fund market show that the performance of principal component risk parity portfolio(PCRPP) is better than that of equal weight portfolio(EWP) and traditional risk parity portfolio(RPP). That is to say, not only the PCRPP in this paper has much lower risk than EWP and RPP, but also slightly better than EWP and RPP in terms of average return. Moreover, the study of dividing the underlying assets shows that the PCRPP in this paper is not sensitive to the underlying assets. The PCRPP in this paper is better than EWP and RPP for both the better performing funds and the worse performing funds. In addition, the empirical results on dynamic portfolio adjustments show that it is not appropriate to adjust asset allocation too frequently when the expected rate of return is calculated using the arithmetic mean.

关键词： Fund of funds(FOF) mutual funds portfolio risk principal component analysis risk parity portfolio

Wireless multisite sensing systems for continuous physiological monitoring

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Science China Materials 2024年第6期67卷 2045-2047页

作者： Ruilai wei Qilin hua Guozhen Shen School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081China Institute of Flexible Electronics Beijing Institute of TechnologyBeijing 102488China

Respiratory diseases rank as the third leading cause of adult mortality[1],while cardiopulmonary and gastrointestinal issues are the primary cause of death within the first five years of a child’s life[2].The monitoring of cardiac,respiratory,and gastrointestinal sounds plays a vital role in routine care,as alterations or absence of these body sounds can serve as indicators of underlying diseases.

关键词： routine continuous monitoring

Mobile Crowdsourcing Task Allocation Based on Dynamic Self-Attention GANs

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Computers, Materials & Continua 2024年第4期79卷 607-622页

作者： kai wei Song Yu Qingxian Pan School of Computer and Control Engineering Yantai UniversityYantai264005China School of Computer and Information Science Southwest UniversityChongqing400715China

Crowdsourcing technology is widely recognized for its effectiveness in task scheduling and resource *** traditional methods for task allocation can help reduce costs and improve efficiency,they may encounter challenges when dealing with abnormal data flow nodes,leading to decreased allocation accuracy and *** address these issues,this study proposes a novel two-part invalid detection task allocation *** the first step,an anomaly detection model is developed using a dynamic self-attentive GAN to identify anomalous *** to the baseline method,the model achieves an approximately 4%increase in the F1 value on the public *** the second step of the framework,task allocation modeling is performed using a twopart graph matching *** phase introduces a P-queue KM algorithm that implements a more efficient optimization *** allocation efficiency is improved by approximately 23.83%compared to the baseline *** results confirm the effectiveness of the proposed framework in detecting abnormal data nodes,enhancing allocation precision,and achieving efficient allocation.

关键词： Mobile crowdsourcing task allocation anomaly detection GAN attention mechanisms