检索结果-南通市图书馆

Aggregate 2023年第3期4卷 55-70页

作者： Govardhana Babu Bodedla Xunjin Zhu wai-Yeung wong Department of Applied Biology&Chemical Technology and Research Institute for Smart Energy The Hong Kong Polytechnic UniversityHong KongP.R.China The Hong Kong Polytechnic University Shenzhen Research Institute ShenzhenP.R.China Department of Chemistry Hong Kong Baptist UniversityHong KongP.R.China

One of the major obstacles of porphyrins is the aggregation-caused quenching(ACQ)of photoluminescence due to the strong intermolecularπ–πinteraction of the planar porphyrin core in the solid ***,ACQ leads to the nonradiative deactivation of the photoexcited states which results in short-lived charge-separated states and thus low photoluminescence and singlet quantum *** phenomenon would limit the utilization of porphyrins in near-infrared fluorescent bioimaging,photodynamic therapy,photocatalytic hydrogen evolution,electrochemiluminescence,and chiroptical ***,to address the ACQ property of porphyrins and enhance the performance of the above applications,a limited number of AIEgen-decorated porphyrins have been designed,synthesized,and tested for their *** has been found that the introduction of AIEgens,such as tetraphenylethylene,diphenylacrylonitrile,(3,6-bis-(1-methyl-4-vinylpyridinium)-carbazole diiodide,and iridium motif into the porphyrin core,transformed the porphyrins from ACQ to aggregation-induced emission(AIE)in their solid state due to the reduced strong intermolecularπ–πstacking of ***,such porphyrins containing AIE features are employed as potential candidates in the above-mentioned *** this review,we summarize the AIEgen-decorated porphyrins which have been published to date,and also discuss the benefits of converting porphyrins from ACQ to AIE for enhanced performance within each *** far as we know,there is no review that summarizes the structures and applications of AIEgen-decorated porphyrins to ***,we presume that this review would be helpful to design more efficient AIEgen-decorated porphyrins for a wide range of applications in the future.

关键词： aggregation-caused quenching aggregation-induced emission AIE luminogen FRET and solid state emission porphyrin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Inhibitory effect of different Dendrobium species on LPS-induced inflammation in macrophages via suppression of MAPK pathways

引用

Chinese Journal of Natural Medicines 2018年第7期16卷 481-489页

作者： ZENG Qiang Chun-Hay Ko Wing-Sum Siu LI kai-kai Chun-wai wong HAN Xiao-Qiang YANG Liu Clara Bik-San Lau HU Jiang-Miao Ping-Chung Leung Institute of Chinese Medicine The Chinese University of Hong Kong State Key Laboratory of Phytochemistry and Plant Resources in West China The Chinese University of Hong Kong Shenzhen Research Institute The Chinese University of Hong Kong Kunming Institute of Botany Chinese Academy of Sciences

Dendrobii Caulis(DC), named ‘Shihu' in Chinese, is a precious herb in traditional Chinese medicine. It is widely used to nourish stomach, enhance body fluid production, tonify "Yin" and reduce heat. More than thirty Dendrobium species are used as folk medicine. Some compounds from DC exhibit inhibitory effects on macrophage inflammation. In the present study, we compared the anti-inflammatory effects among eight Dendrobium species. The results provided evidences to support Dendrobium as folk medicine, which exerted its medicinal function partially by its inhibitory effects on inflammation. To investigate the anti-inflammatory effect of Dendrobium species, mouse macrophage cell line RAW264.7 was activated by lipopolysaccharide. The nitric oxide(NO) level was measured using Griess reagent while the pro-inflammatory cytokines were tested by ELISA. The protein expressions of inducible NO synthase(iNOS), cyclooxygenase-2(COX-2) and mitogen-activated protein kinases(MAPKs) phosphorylation were evaluated by Western blotting analysis. Among the eight Dendrobium species, both water extracts of D. thyrsiflorum ***(DTW) and D. chrysotoxum Lindl(DCHW) showed most significant inhibitory effects on NO production in a concentration-dependent manner. DTW also significantly reduced TNF-α, MCP-1, and IL-6 production. Further investigations showed that DTW suppressed iNOS and COX-2 expression as well as ERK and JNK phosphorylation, suggesting that the inhibitory effects of DTW on LPS-induced macrophage inflammation was through the suppression of MAPK pathways. In conclusion, D. thyrsiflorum *** was demonstrated to have potential to be used as alternative or adjuvant therapy for inflammation.

关键词： Dendrobium species Anti-inflammation Macrophage MAPK pathways

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Steering S-scheme charge transfer via interfacial dipoles induced by amine-containing polyelectrolytes

引用

Science China Chemistry 2023年第7期66卷 2098-2108页

作者： Tao Li Chuang Feng Biquan Xiong Xuhui Zhu Zhicai He wai-Yeung wong Institute of Polymer Optoelectronic Materials and Devices State Key Laboratory of Luminescent Materials and DevicesSchool of Material Science and EngineeringSouth China University of TechnologyGuangzhou 510640China Department of Applied Biology&Chemical Technology and Research Institute for Smart Energy The Hong Kong Polytechnic UniversityHung HomHong KongChina

The lack of a robust interfacial driving source over multicomponent photocatalysts is an essential contributor to the sluggish spatial charge transfer across the heterointerface and severe carrier recombination,thereby rendering maneuvering charge transfer of composite materials a thorny ***,we demonstrate an electric dipole moment-driven charge transfer photosystem utilizing amine-containing polyfluorene polyelectrolyte(i.e.,PFN)and inorganic semiconductor matrices(i.e.,WO_(3))as the building blocks to direct the interfacial charge transfer,effectively targeting the photoexcited charge carriers to the active *** results and theoretical simulations reveal that the electronic coupling interaction between the pendant electron-rich amine groups along the PFN backbone and WO_(3)surface enables the nonuniform charge distribution at the interface over the WO_(3)@PFN heterojunction,which ultimately fosters the formation of interfacial dipoles oriented from conjugated macromolecular backbone of PFN to the surface of WO_(3)*** interfacial dipoles with excellent charge transfer kinetics spontaneously activate the unidirectional and accelerated S-scheme charge motion from the WO_(3)framework to the conjugated chain of PFN due to the suitable band offsets at the interface,thus endowing WO_(3)@PFN heterostructures with a significantly enhanced net efficiency of *** findings would provide some insights into the design of advanced heterojunction photocatalysts for solar energy conversion as well as the study of the working mechanism of polyelectrolyte interlayers in optoelectronic devices.

关键词： photocatalysis heterojunction interfacial dipole polyelectrolyte S-scheme

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Engineering advanced dynamic biomaterials to optimize adoptive T-cell immunotherapy

引用

Engineered Regeneration 2021年第1期2卷 70-81页

作者： wai Ki wong Bohan Yin Anel Rakhmatullina Jingying Zhou Siu Hong Dexter wong Department of Bioengineering Imperial College LondonLondon SW72AZUnited Kingdom Department of Biomedical Engineering The Hong Kong Polytechnic UniversityKowloonHong KongChina School of Biomedical Sciences The Chinese University of Hong KongShatinHong KongChina

Adoptive T-cell therapy(ACT)is a promising therapeutic approach based on the concept of potent T-cell mediated immunity against the *** outcome of antigen-specific T-cells responses relies on the interaction between T-cells and antigen-presenting cells,which provides signals for generating different T-cell phenotypes with different roles in tumor ***,such interaction is often not optimal in vivo and results in low therapeutic *** reach the full potential of the T-cell response,current research put effort into developing dynamic biomaterials as artificial antigen-presenting cells to study and regulate the T-cell activity for controlling T-cell *** this perspective,we provide(1)an overview of ACT and general T-cells behaviors,(2)explore the insight on how biomaterials can be used for studying and regulating T-cell behaviors,(3)and discuss conceptual gaps in knowledge for biomaterials-based immunotherapy.

关键词： T-cell mechanobiology Dynamic nanobiomaterials Adoptive T-cell immunotherapy T-Ligand presentation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A fuzzy risk assessment model used for assessing the introduction of African swine fever into Australia from overseas

引用

Artificial Intelligence in Agriculture 2023年第1期7卷 27-34页

作者： Hongkun Liu YongLin Ren Huanhuan Chu Hu Shan Kok wai wong College of Veterinary Medicine Qingdao Agriculture UniversityQingdaoPR China Murdoch University 90 South StreetMurdochWestern Australia 6150Australia

African swine fever(ASF)is a contagious and lethal hemorrhagic disease with a high case fatality *** 2007,ASF has been spreading into many countries,especially in Europe and *** that there is no effective vaccine and treatment to deal with ASF,prevention is an important way for a country to avoid the effects of the *** is currently ASF-free but the disease has been reported in many neighboring countries,such as Indonesia,Timor-Leste,and Papua New ***,it is necessary for Australia to maintain hypervigilance to prevent the ASF *** this paper,we propose the use of fuzzy concepts to establish a fuzzy risk assessment model to predict the ASF introduction risk in *** the analysis,the international passengers(IP)and international import trade(IIT)are concluded as the two main ASF introduction factors based on transmission features and past *** the established fuzzy risk assessment model based on the analysis of the 2019 and 2020 data,the risks of ASF introduction into Australia are considered to be *** model further deduced that the Asian region was the major source of potential ***,in order to validate the effectiveness of the established fuzzy risk assessment model,the qualitative data from the Department for Environment,Food&Rural Affairs of the United Kingdom was *** the validation results,it has shown that the results were consistent when the same data is adopted,and thus proved that the functionality of the established fuzzy risk assessment model for assessing the risk in Australia.

关键词： Risk assessment Fuzzy model African swine fever(ASF) ASF introduction Australia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Epidemiology and Clinical Outcomes of Metabolic(Dysfunction)-associated Fatty Liver Disease

引用

Journal of Clinical and Translational Hepatology 2021年第6期9卷 972-982页

作者： Huapeng Lin Xinrong Zhang Guanlin Li Grace Lai-Hung wong Vincent wai-Sun wong Department of Medicine and Therapeutics State Key Laboratory of Digestive diseaseand Medical Data Analytics CentreThe Chinese University of Hong KongHong KongChina

Metabolic(dysfunction)-associated fatty liver disease(MAFLD)is currently the most common chronic liver disease and affects at least a quarter of the global adult *** has rapidly become one of the leading causes of hepatocellular carcinoma and cirrhosis in Western *** this review,we discuss the nomenclature and definition of MAFLD as well as its prevalence and incidence in different geographical *** cardiovascular disease remains the leading cause of death in MAFLD patients,the proportion of patients dying from hepatic complications increases sharply as the disease progresses to advanced liver fibrosis and *** addition,patients with MAFLD are at increased risk of various extrahepatic *** a causal relationship between MAFLD and extrahepatic cancers has not been established,clinicians should recognize the association and consider cancer screening(e.g.,for colorectal cancer)as appropriate.

关键词： Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis Obesity Prevalence Incidence Hepatocellular carcinoma Cirrhosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Design, Synthesis, Photophysical Studies and Electrochemistry of Carbazole-, Oxadiazole-, and Oxadiazole-Triarylamine-Containing Rhenium(Ⅰ) Diimine Alkynyl Complexes

引用

Chinese Journal of Chemistry 2014年第10期32卷 1015-1021页

作者： wai-Kin Chung Keith Man-Chung wong Vivian Wing-Wah Yam and Department of ChemistryThe University of Hong KongPokfulam RoadHong KongChina

A series of rhenium(I)diimine alkynyl complexes with various electron-and hole-transporting moieties has been synthesized and *** electronic absorption,emission and electrochemical properties have also been studied.

关键词： electrochemistry luminescence metal alkynyl rhenium(Ⅰ)diimine,UV/Vis spectroscopy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optimal location query based on k nearest neighbours

引用

Frontiers of Computer Science 2021年第2期15卷 105-117页

作者： Yubao LIU Zitong CHEN Ada wai-Chee FU Raymond Chi-Wing wong Genan DAI School of Data and Computer Science Sun Yat-Sen UniversityGuangzhou510006China Guangdong Key Laboratory of Big Data Analysis and Processing Guangzhou510006China Department of Computer Science and Engineering Chinese University of Hong KongHong Kong999077China Department of Computer Science and Engineering The Hong Kong University of Science and TechnologyHong Kong999077China

Optimal location query in road networks is a basic operation in the location intelligence *** a set of clients and servers on a road network,the purpose of optimal location query is to obtain a location for a new server,so that a certain objective function calculated based on the locations of clients and servers is *** works assume no labels for servers and that a client only visits the nearest *** assumptions are not realistic and it renders the existing work not useful in many *** this paper,we relax these assumptions and consider the k nearest neighbours(KNN)of *** introduce the problem of KNN-based optimal location query(KOLQ)which considers the k nearest servers of clients and labeled *** also introduce a variant problem called relocation KOLQ(RKOLQ)which aims at relocating an existing server to an optimal *** main analysis algorithms are proposed for these *** experiments on the real road networks illustrate the efficiency of our proposed solutions.

关键词： optimal location query k nearest neighbours road network

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Overview of Terahertz Antennas

引用

China Communications 2020年第7期17卷 124-165页

作者： Yejun He Yaling Chen Long Zhang Sai-wai wong Zhi Ning Chen Guangdong Engineering Research Center of Base Station Antennas and Propagation Shenzhen Key Laboratory of Antennas and PropagationCollege of Electronics and Information EngineeringShenzhen UniversityShenzhen 518060China Department of Electrical and Computer Engineering National University of Singapore117583Singapore

The terahertz(THz)antennas,which have features of small size,wide frequency bandwidth and high data rate,are important devices for transmitting and receiving THz electromagnetic waves in the emerging THz ***,most of THz antennas suffer from relatively high loss and low fabrication precision due to their small sizes in high frequency bands of THz ***,this paper presents a detailed overview of the most recent research on the performance improvement of THz ***,the development of THz antennas is briefly reviewed and the basic design ideas of THz antennas are ***,THz antennas are categorized as metallic antennas,dielectric antennas and new material *** that,the latest research progress in THz photoconductive antennas,THz horn antennas,THz lens antennas,THz microstrip antennas and THz on-chip antennas are *** particular,the practical difficulties for the development of THz antennas are discussed with promising *** addition,this paper also presents a short review of the process technology of THz ***,the vital challenges and the future research directions for THz antennas are presented.

关键词： sizes directions dielectric

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Survey on Recent Advances and Challenges in Reinforcement Learning Methods for Task-oriented Dialogue Policy Learning

引用

Machine Intelligence Research 2023年第3期20卷 318-334页

作者： wai-Chung Kwan Hong-Ru Wang Hui-Min Wang Kam-Fai wong The Systems Engineering and Engineering Management Department The Chinese University of Hong KongHong Kong 999077China

Dialogue policy learning(DPL)is a key component in a task-oriented dialogue(TOD)*** goal is to decide the next action of the dialogue system,given the dialogue state at each turn based on a learned dialogue *** learning(RL)is widely used to optimize this dialogue *** the learning process,the user is regarded as the environment and the system as the *** this paper,we present an overview of the recent advances and challenges in dialogue policy from the perspective of *** specifically,we identify the problems and summarize corresponding solutions for RL-based dialogue policy *** addition,we provide a comprehensive survey of applying RL to DPL by categorizing recent methods into five basic elements in *** believe this survey can shed light on future research in DPL.

关键词： Dialogue policy learning(DPL) task-oriented dialogue system(TOD) reinforcement learning(RL) dialogue system Markov decision process

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：