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SCREENING OF MEDICINAL PLANTS FROM REUNION ISLAND FOR ANTIMALARIAL ACTIVITY

Advances in Biological Chemistry（生物化学进展） 2021年第5期

作者： Gneiny Whad Tchani Kossi Sitsopé Agbeme Kokou Agbékonyi Agbodan Gnon Baba kafui kpegba(laboratoire de chimie organique et des substances naturelles (Lab COSNat) Faculté des Sciences Université de Lomé Lomé Togo laboratoire de Génie des Procédés et Ressources naturelles (LAGEPREN) Département de chimie Université de Lomé Lomé Togo)

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World Journal of Traditional Chinese Medicine 2015年第4期1卷 95-96页

作者： Ledoux Allison Cao Martine Pierre-Eric Campos Grondin Isabelle Smadja Jacqueline Frédérich Michel CIRM Laboratoire de pharmacognosie Université de Liège LCSNSA Laboratoire de Chimie des Substances Naturelles et des Sciences des Aliments Faculté des Sciences et Technologies-Université de La Réunion

According to the last World Malaria Report,there were an estimated 584 000 malaria deaths worldwide in *** problem of parasite resistance towards available medicines is *** products could play an important role to discover new antimalarial *** aim of the study was to highlight the anti-plasmodial properties of plants used in traditional medicine on the Mascarene Islands.85

关键词： SCREENING OF MEDICINAL PLANTS FROM REUNION ISLAND FOR ANTIMALARIAL ACTIVITY IC

Phytochemical Study and Comparative Antioxidant Activity of Extracts from Aerial Parts of <i>Chenopodium ambrosioides</i>Linn. (Chenopodiaceae)

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Advances in Biological Chemistry 2021年第5期11卷 220-233页

作者： Gneiny Whad Tchani Kossi Sitsopé Agbeme Kokou Agbékonyi Agbodan Gnon Baba kafui kpegba laboratoire de chimie organique et des substances naturelles (Lab COSNat) Faculté des Sciences Université de Lomé Lomé Togo laboratoire de Génie des Procédés et Ressources naturelles (LAGEPREN) Département de Chimie Université de Lomé Lomé Togo

The use of Chenopodium ambrosioides in some communities in Togo reveals its importance and its medicinal properties. The plant is often infused for medicinal drinks before use. Thus, through a comparative study, this work focused on the identification of the different phytochemical groups and then on the anti-radical capacities of ethanolic and aqueous extracts of aerial parts (lea- ves and seeds) of Chenopodium ambrosiooides obtained by maceration and infusion. The phytochemical tests, carried out on the various extracts, showed that they contained certain biomolecules such as flavonoids and tannins. Likewise, the presence of terpenoids and terpenes has been detected. However, it is only in aqueous extracts that the alkaloids have been revealed. The determination of the polyphenol content of the extracts revealed that the aqueous infusion contains 25.699 mgGAE/g DE, followed by the aqueous macera

PHYTOCHEMICAL STUDY OF CITRUS AURANTIUM BERGAMIA: ANALYSIS OF BIOACTIVE COMPOUNDS PRESENT IN JUICE, TISSUES AND ESSENTIAL OIL OF THE FRUIT

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World Journal of Traditional Chinese Medicine 2015年第4期1卷 104-104页

作者： E.Tsiokanos N.Tsafantakis C.Kanakis C.Stévigny A-L.Skaltsounis laboratoire de Pharmacognosie Bromatologie et Nutrition humaine Université Libre de Bruxelles ULB laboratoire de Pharmacognosie et chimie des substances naturelles Université Nationale et Capodistrienne d'Athènes

Flavonoids are secondary metabolites from aromatic plants and one of the most present classes in the vegetable *** is thanks to its antioxidant properties but also through its benefits on the human body that these molecules have become the center of interest of many researchers in recent *** are found in large quantities in citrus *** aim of this study is

关键词： ANALYSIS OF BIOACTIVE COMPOUNDS PRESENT IN JUICE PHYTOCHEMICAL STUDY OF CITRUS AURANTIUM BERGAMIA TISSUES AND ESSENTIAL OIL OF THE FRUIT

Synthesis and Biological Evaluation of a Highly Constrained Analogue of Methylthioadenosine (MTA)

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International Journal of Organic Chemistry 2012年第4期2卷 398-403页

作者： Gustavo Senra G. de Carvalho Rafael Mafra de P. Dias Jean-Louis Fourrey Vania L. Silva Cláudio G. Diniz Adilson D. da Silva departamento de Parasitologia Microbiologia e Imunologia Instituto de Ciências Biológicas (ICB) Universidade Federal de Juiz de Fora Juiz de Fora-MG Brasil departamento de Química Instituto de Ciências Exatas (ICE) Universidade Federal de Juiz de Fora Juiz de Fora-MG Brasil Institut de chimie des substances naturelles Gif-sur-Yvette Cedex France

We describe the synthesis and the antibacterial evaluation 2’,N3-cyclonucleoside 3 analogue of MTA that is characterized by the presence of an additional linkage between the heterocyclic ring and the sugar moiety.

关键词： Synthesis Biological Evaluation Antibacterial Analogue Methylthioadenosine

A Phelipanche ramosa KAI2 protein perceives strigolactones and isothiocyanates enzymatically

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Plant Communications 2021年第5期2卷 132-147页

作者： Alexandre de Saint Germain Anse Jacobs Guillaume Brun Jean-Bernard Pouvreau Lukas Braem David Cornu Guillaume Clavé Emmanuelle Baudu Vincent Steinmetz Vincent Servajean Susann Wicke Kris Gevaert Philippe Simier Sofie Goormachtig Philippe delavault François-Didier Boyer Institut Jean-Pierre Bourgin INRAEAgroParisTechUniversitéParis-Saclay78000 VersaillesFrance department of Plant Biotechnology and Bioinformatics Ghent University9052 GentBelgium Center for Plant Systems Biology VIB9052 GentBelgium department of Biomolecular Medicine Ghent University9000 GhentBelgium Center for Medical Biotechnology VIB9000 GhentBelgium laboratoire de Biologie et Pathologie Végétales(LBPV) Equipe d’Accueil 1157Universitéde Nantes44000 NantesFrance Institute for Biology Humboldt-Universit€at zu Berlin10115 BerlinGermany UniversitéParis-Saclay CEACNRSInstitute for Integrative Biology of the Cell(I2BC)91198Gif-sur-YvetteFrance UniversitéParis-Saclay CNRSInstitut de Chimie des Substances NaturellesUPR 230191198Gif-sur-YvetteFrance

Phelipanche ramosa is an obligate root-parasitic weed that threatens major crops in central *** order to germinate,it must perceive various structurally divergent host-exuded signals,including isothiocyanates(ITCs)and strigolactones(SLs).However,the receptors involved are still ***,we identify five putative SL receptors in *** and show that PrKAI2d3 is involved in the stimulation of seed *** demonstrate the high plasticity of PrKAI2d3,which allows it to interact with different chemicals,including *** SL perception mechanism of PrKAI2d3 is similar to that of endogenous SLs in non-parasitic *** provide evidence that PrKAI2d3 enzymatic activity confers hypersensitivity to ***,we demonstrate that methylbutenolide-OH binds PrKAI2d3 and stimulates *** germination with bioactivity comparable to that of *** study demonstrates that *** has extended its signal perception system during evolution,a fact that should be considered for the development of specific and efficient biocontrol methods.

关键词： a/b-hydrolase receptor seed germination stimulant strigolactones isothiocyanates Phelipanche ramosa

New Strigolactone Analogs as Plant Hormones with Low Activities in the Rhizosphere

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Molecular Plant 2014年第4期7卷 675-690页

作者： Francois-Didier Boyer Alexandre de Saint Germain Jean-Bernard Pouvreau Guillaume Clave Jean-Paul Pillot Amelie Roux Amanda Rasmussen Stephen depuydt Dominique Lauresserguesh Nicolas Frei dit Frey Thomas S.A. Heugebaert Christian V. Stevens Danny Geelen Sofie Goormachtig Catherine Rameau Institut Jean-Pierre Bourgin UMR1318 Institut National de la Recherche Agronomique (INRA)-AgroParisTech Route de Saint-Cyr (RD 10) F-78026 Versailles Cedex France Centre de Recherche de Gif Institut de Chimie des Substances Naturelles UPR2301 Centre National de la Recherche Scientifique (CNRS) 1 avenue de la Terrasse F-91198 Gif-sur-Yvette Cedex France laboratoire de Biologie et de Pathologie Vegetales EA 1157 SFR 4207 QUASAV Universite de Nantes 44322 Nantes France Plant Production Faculty of Bioscience Engineering Ghent University Coupure links 653 Ghent 9000 Belgium Present address: School of Biosciences Division of Plant and Crop Production The University of Nottingham Sutton Bonington Leicestershire LE12 5RD UK department of Plant Systems Biology VIB Ghent 9052 Belgium department of Plant Biotechnology and Bioinformatics Ghent University Ghent 9052 Belgium laboratoire de Recherche en Sciences Vegetales UMR 5546 Universite de Toulouse- Centre National de la Recherche Scientifique (CNRS) BP 42617 Auzeville F-31326 Castanet-Tolosan France Research Group SynBioC Department of Sustainable Organic Chemistry and Technology Faculty of Bioscience Engineering Ghent University Coupure links 653 B-9000 Gent Belgium

Strigolactones （SLs） are known not only as plant hormones, but also as rhizosphere signals for establishing symbiotic and parasitic interactions. The design of new specific SL analogs is a challenging goal in understanding the basic plant biology and is also useful to control plant architectures without favoring the development of parasitic plants. Two different molecules （23 （3＇-methyI-GR24）, 31 （thia-3＇-methyl-debranone-like molecule）） already described, and a new one （AR36）, for which the synthesis is presented, are biologically compared with the well-known GR24 and the recently identified CISA-1. These different structures emphasize the wide range of parts attached to the D-ring for the bioactivity as a plant hormone. These new compounds possess a common dimethylbutenolide motif but their structure varies in the ABC part of the molecules： 23 has the same ABC part as GR24, while 31 and AR36 carry, respectively, an aromatic ring and an acyclic carbon chain. detailed information is given for the bioactivity of such derivatives in strigolactone synthesis or in perception mutant plants （pea rmsl and rms4, Arabidopsis max2 and, max4） for different hormonal functions along with their action in the rhizosphere on arbuscular mycorrhizal hyphal growth and parasitic weed germination.

关键词： strigolactones synthetic analogs Pisum sativum Arabidopsis root parasitic plants Gigaspora rosea plant growth regulator.