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Regression analysis of squeezing-induced hybrid nanofluid flow in Darcy-Forchheimer porous medium

Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 193-208页

作者： k.MUHAMMAD M.SARFRAZ Department of Humanities and Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of Mathematics Quaid-i-Azam University

this article presents a mathematical model addressing a scenario involving a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing velocity. the space between these plates contains a Darcy-Forchheimer porous medium. A mixture of water-based fluid with gold(Au) and silicon dioxide(Si O2) nanoparticles is formulated. In contrast to the conventional Fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform magnetic field is applied perpendicular to the flow direction, invoking magnetohydrodynamic(MHD) effects. Further, the model accounts for Joule heating, which is the heat generated when an electric current passes through the fluid. the problem is solved via NDSolve in MAtHEMAtICA. Numerical and statistical analyses are conducted to provide insights into the behavior of the nanomaterials between the parallel plates with respect to the flow, energy transport, and skin *** findings of this study have potential applications in enhancing cooling systems and optimizing thermal management strategies. It is observed that the squeezing motion generates additional pressure gradients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vigorously between the plates, increasing the flow velocity. As the fluid experiences higher flow rates due to the increased squeezing effect, it spends less time in the region between the plates. the thermal relaxation, however, abruptly changes the temperature, leading to a decrease in the temperature fluctuations.

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Effects of P301L-tAU on post-translational modifications of microtubules in human iPSC-derived cortical neurons and tAU transgenic mice

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Neural Regeneration Research 2025年第8期20卷 2348-2360页

作者： Mohamed Aghyad Al kabbani Christoph köhler Hans Zempel Institute of Human Genetics Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Center for Molecular Medicine Cologne(CMMC) University of CologneCologneGermany Center Anatomy Department ⅡMedical FacultyUniversity of CologneCologneGermany

tAU is a microtubule-associated protein that promotes microtubule assembly and stability in the *** is missorted and aggregated in an array of diseases known as *** are essential for neuronal function and regulated via a complex set of post-translational modifications,changes of which affect microtubule stability and dynamics,microtubule interaction with other proteins and cellular structures,and mediate recruitment of microtubule-severing *** impairment of microtubule dynamics causes neuronal dysfunction,we hypothesize cognitive impairment in human disease to be impacted by impairment of microtubule *** therefore aimed to study the effects of a disease-causing mutation of tAU(P301L)on the levels and localization of microtubule post-translational modifications indicative of microtubule stability and dynamics,to assess whether P301L-tAU causes stability-changing modifications to *** investigate tAU localization,phosphorylation,and effects on tubulin post-translational modifications,we expressed wild-type or P301L-tAU in human MAPt-kO induced pluripotent stem cell-derived neurons(i Neurons)and studied tAU in neurons in the hippocampus of mice transgenic for human P301L-tAU(p R5 mice).Human neurons expressing the longest tAU isoform(2N4R)with the P301L mutation showed increased tAU phosphorylation at the At8,but not the p-Ser-262 epitope,and increased polyglutamylation and acetylation of microtubules compared with endogenous tAU-expressing neurons.P301L-tAU showed pronounced somatodendritic presence,but also successful axonal enrichment and a similar axodendritic distribution comparable to exogenously expressed 2N4R-wildtype-tAU.P301L-tAU-expressing hippocampal neurons in transgenic mice showed prominent missorting and tauopathy-typical At8-phosphorylation of tAU and increased polyglutamylation,but reduced acetylation,of microtubules compared with non-transgenic *** sum,P301L-tAU results in changes in micr

关键词： human induced pluripotent stem cell microtubules P301L pR5 mice tAU tauopathy tubulin code

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From a CCtV Documentary Director to an ENtREPRENEUR OF tIBEtAN BOUtIQUE HOtELS

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China's tibet 2016年第5期27卷 46-53页

作者： gawa tashi Padma Dorje

Some media have rated the Songtsen Linka as the best boutique hotel chain in *** Dorje,who was born in Shangrila,Yunnan,is the founder of the tibetan hotel *** to High Appreciation for CCtV twenty years ago,Padma Dorj... 详细信息

关键词：酒店精品企业家纪录片导演 Padma 创始人

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transport mechanism in chemically reactive hybrid nanofluid flow containing gyrotactic micro-organisms over a curved oscillatory surface

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 177-192页

作者： M.NAVEED M.IMRAN t.ASGHAR Z.ABBAS Department of Mathematics Division of Science and TechnologyUniversity of Education Department of Mathematics The Islamia University of Bahawalpur

this paper examines the transport analysis, including both heat transfer and mass transfer, in hybrid nanofluid flow containing gyrotactic microorganisms towards a curved oscillatory surface. the influence of magnetic fields is also inspected in terms of their physical characteristics. to depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterogeneous and homogeneous chemical reactions are also incorporated. Utilizing a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorganism field, and energy. An analytical solution to the obtained flow equations is achieved utilizing the homotopy analysis method(HAM).the effects of significant flow parameters on the pressure and microorganism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via graphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. Graphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homogeneous reaction strength parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterogeneous reaction strength *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorganism difference parameter, and the bio-convective Lewis number.

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AN ESSAY ON tHE tRADItION OF tIBEtAN tEA

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China's tibet 2014年第4期25卷 47-51页

作者： gawa tashi

One day,I was searching the Internet to find a gift for a distant *** I browsed lists of teas,immediately I found something that has been regarded as a necessity of life since I was young and nowadays had been package... 详细信息

关键词：传统茶网上搜索收藏品吸引力

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Human endogenous retrovirus type-W and multiple sclerosis–related smoldering neuroinflammation

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Neural Regeneration Research 2025年第3期20卷 813-814页

作者： Joel Gruchot Laura Reiche Andrew Chan Robert Hoepner Patrick küry Department of Neurology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neurology InselspitalBern University Hospital and University of BernBernSwitzerland

Introduction to human endogenous retrovirus type-W(HERV-W): Genomic inheritance from the past includes retroviral sequences that have been stably incorporated into our genomes and account for up to 8% of human DNA.

关键词： endogenous inflammation Human

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Nucleoside modified mRNA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord

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Neural Regeneration Research 2025年第8期20卷 2311-2312页

作者： krisztián Pajer tamás Bellák Antal Nógrádi Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spinal cord injury and treatment opportunities:the adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular *** the spinal cord neurons have the capacity to regenerate their axons,the expression of growth inhibitory factors,lack or suppression of proper guidance cues,and profound inflammatory responses do not permit successful regeneration(khyeam et al.,2021).

关键词： injured capacity modified

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From Waiter to StRING ARtISt

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China's tibet 2016年第3期27卷 62-67页

作者： gawa tashi Gerong Norbu

One night six or seven years ago,while I was having dinner with several friends at Makye Ame tibetan Restaurant in Beijing,the house String(a bowed string instrument,also known as the ox horn instrument)player,Gerong Norbu,who just finished his set,came off the stage and had a couple of drinks with *** was a typical khampa man:tall and darkly handsome,a bit rough around the edges,but when I talked with him,he turned out to

关键词：弓弦乐器艺术家服务员字符串割绒

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the Isentropic Exponent of Single-Ionized Mono-Atomic Plasmas

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Plasma Science and technology 2012年第8期14卷 699-701页

作者： k.t.A.L.BURM PlasmAIX for Plasma Research Heimerik 472440 GeelBelgium

the isentropic exponent of single-ionized mono-atomic plasmas in thermal equilib- rium is studied. Its behavior as a function of the ionization degree and temperature is examined for argon and zinc plasmas at two pressures （1 bar and 1 mbar, 1 mPa and 1 Pa）, respectively. the results show that for the two sorts of plasma the isentropic exponent equals typically about 1.1-1.2 within a considerably wide range of the ionization degree （5%-80%）.

关键词： plasma modelling isentropic exponent

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Pressure Drop of Non-Newtonian Liquid Flow through Elbows

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Chinese Journal of Chemical Engineering 2000年第4期8卷 388-390页

作者： t.k.Banerjee S.k.DAS Chemical Engineering Department University of Calcutta92A.P.C.RoadCalcutta-700 009IndiaChemical Engineering DepartmentUniversity of Calcutta92A.P.C.RoadCalcutta-700 009India

Experimental data on the pressure drop across different types of elbow for non-Newtonian pseudoplastic liquid flow in laminar condition have been presented. A generalized correlation has been developed for predicting ... 详细信息

关键词： non-Newtonian liquid pseudoplastic elbow

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