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Data-driven nonlinear control of a solid oxide fuel cell system

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Journal of Central South University 2012年第7期19卷 1892-1901页

作者：李益国沈炯 k.y.lee 刘西陲费文哲 key Laboratory of Energy Thermal Conversion and Control of Ministry of Education(School of Energy and Environment Southeast University) Department of Electrical and Computer Engineering Baylor UniversityWacoTX 76798-7356USA

Solid oxide fuel cells (SOFCs) are considered to be one of the most important clean,distributed resources. However,SOFCs present a challenging control problem owing to their slow dynamics,nonlinearity and tight operating constraints. A novel data-driven nonlinear control strategy was proposed to solve the SOFC control problem by combining a virtual reference feedback tuning (VRFT) method and support vector machine. In order to fulfill the requirement for fuel utilization and control constraints,a dynamic constraints unit and an anti-windup scheme were adopted. In addition,a feedforward loop was designed to deal with the current disturbance. Detailed simulations demonstrate that the fast response of fuel flow for the current demand disturbance and zero steady error of the output voltage are both achieved. Meanwhile,fuel utilization is kept almost within the safe region.

关键词： solid oxide fuel cell (SOFC) data-driven method virtual reference feedback tuning (VRFT) support vector machine(SVM) anti-windup

The effect of the magnetic fields from three different configurations of the MRIgRT systems on the dose deposition from lateral opposing photon beams in a laryngeal geometry–A Monte Carlo study

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Radiation Medicine and Protection 2021年第3期2卷 103-111页

作者： Vivien W.S.Chu Monica W.k.kan Louis k.y.lee kenneth C.W.Wong Macy Tong Anthony T.C.Chan Department of Clinical Oncology Prince of Wales HospitalHong KongChina Department of Clinical Oncology The Chinese University of Hong KongHong KongChina Medical Center The Chinese University of Hong KongChina State key Laboratory of Translational Oncology Sir YK Pao Center for CancerDepartment of Clinical OncologyHong Kong Cancer Institute and Prince of Wales HospitalThe Chinese University of Hong KongHong KongChina

Objective:To investigate the impact of different magnetic field strengths and orientations on the dose deposition from lateral opposing photon beams irradiating a laryngeal geometry,with particular attention focused on the dose homogeneity of the area around the air cavity inside the ***:Geant4 simulation toolkit was used to perform Monte Carlo simulations on a phantom resembling the *** energy spectrum of a 6 MV photon beam from a Varian Clinac iX machine was used to provide the source of *** configurations of the Magnetic Resonance Image-Guided Radiation Therapy(MRIgRT)system were simulated:the Fixed Cylindrical(FC)geometry,the Longitudinal Rotating Biplanar(LRBP)geometry,and the Transverse Rotating Biplanar(TRBP)*** magnetic fields of different field strengths were *** relative dose maps and the homogeneity index(HI)were obtained for ***:The LRBP geometry together with a magnetic field strength of 0.5 T produced the most homogeneous dose distribution with a HI of 0.139 for the region of interest around the air cavity,compared with a HI of 0.180 when the magnetic field was *** TRBP geometry,the dose distribution shifted towards the cranial direction,leading to a region of hot spots at the superior edge and a region of cold spots at the inferior edge of the irradiated *** HI around the air cavity was therefore *** addition,strong electron streaming effect(ESE)was *** the FC geometry,hot and cold spots were formed around the air cavity which increased the ***:Out of the three configurations of the MRIgRT systems,the LRBP geometry produced the most clinically beneficial dose distribution in which it provided a higher dose to the treatment area and a boost in dose to the tissue immediately adjacent to the air cavity.

关键词： Monte Carlo MRIgRT MR-Linac Magnetic field Air cavity

比较胸片、胸部数字体层合成及低剂量MDCT检测肺磨玻璃样小结节:拟人胸部模型研究

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国际医学放射学杂志 2015年第1期 101-101页

作者： k.W.Doo E.y.kang H.S.yong S.y.Ham k.y.lee J.y.Choo Department of Radiology Korea University Guro HospitalKorea University College of Medicine

目的旨在使用拟人胸部模型评估胸片(CXR)、胸部的数字体层合成(DT)和低剂量多层CT(LDCT)检测肺磨玻璃(GGO)小结节的诊断性能。方法人工肺结节被放置于

关键词：胸部躯干胸片低剂量小结节体层

以CT作参照比较数字X线断层影像和胸片在评估气道病变方面的诊断效能

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国际医学放射学杂志 2016年第6期 703-703页

作者： J.y.Choo k.y.lee Ami yu J.H.kim S.H.lee J.W.Choi 郑文松 Department of Radiology Korea University Ansan HospitalKorea University College of Medicine

摘要目的以CT作参照比较数字X线断层影像(DTS)和胸片在评估气道异常方面的诊断效能。方法评价了149例病人的161个数据资料(91个有气道异常,70个无气道异

关键词：胸片 DTS 断层影像诊断效能气道病变 CT

Cortical hem signaling center: functions, development, and potential implications for evolution and brain disorders

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Neural Regeneration Research 2025年第4期20卷 1079-1080页

作者： Victor V.Chizhikov Igor y.Iskusnykh Department of Anatomy and Neurobiology University of Tennessee Health Science CenterMemphisTNUSA

Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical *** such signaling center is the cortical hem,which arises during embryonic development at the telencephalic dorsal midline,adjacent to the choroid plexus and hippocampal primordium(Figure 1A).While the cortical hem has also been described in reptiles and birds,most of our knowledge about the developmental roles of the cortical hem is derived from the analysis in *** cortical hem produces several types of secreted molecules,including wingless-related integration site(Wnt)and bone morphogenetic(Bmp)*** cortical hem is particularly important for the development of the hippocampus,which is involved in learning and memory,and the neocortex,which is the most complex brain region that mediates multiple types of behavior and higher cognitive functions(Mangale et al.,2008;Dal-Valle-Anton and Borrell,2022).

关键词： epithelium Figure center

Exercise preconditioning alleviates ischemia-induced memory deficits by increasing circulating adiponectin

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Neural Regeneration Research 2025年第5期20卷 1445-1454页

作者： Meifeng Zheng Borui Zhang Sonata S y yau kwok-Fai So Li Zhang Haining Ou Department of Rehabilitation Medicine Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation Medicine The Fifth Clinical College of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina key Laboratory of CNS Regeneration(Ministry of Education) Guangdong-Hong Kong-Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation Sciences The Hong Kong Polytechnic UniversityHong Kong Special Administrative RegionChina State key Laboratory of Brain and Cognitive Science Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Center for Exercise and Brain Science School of PsychologyShanghai University of SportShanghaiChina Neuroscience and Neurorehabilitation Institute University of Health and Rehabilitation SciencesQingdaoShandong ProvinceChina

Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug *** exercise enhances neurogenesis and synaptogenesis,and has been widely used for functional rehabilitation after *** this study,we determined whether exercise training before disease onset can alleviate the severity of cerebral *** also examined the role of exercise-induced circulating factors in these *** mice were subjected to 14 days of treadmill exercise training before surgery for middle cerebral artery *** found that this exercise pre-conditioning strategy effectively attenuated brain infarct area,inhibited gliogenesis,protected synaptic proteins,and improved novel object and spatial memory *** analysis showed that circulating adiponectin plays a critical role in these preventive effects of *** activation of adiponectin receptors by Adipo Ron mimicked the effects of exercise,while inhibiting receptor activation abolished the exercise *** summary,our results suggest a crucial role of circulating adiponectin in the effects of exercise pre-conditioning in protecting against cerebral ischemia and supporting the health benefits of exercise.

关键词： adiponectin cerebral ischemia exercise pre-conditioning hippocampus memory function middle cerebral artery occlusion prefrontal cortex synaptic proteins treadmill exercise

A G^E/Equation of State Mixing Rule for Vapor-Liquid Equilibria

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Chinese Journal of Chemical Engineering 1998年第3期6卷 14-28页

作者：屈一新汪文川 lee y.y. Chung k.y. lee y.W. korea Institute of Science and Technology SeoulKorea

A new excess Gibbs free energy/equation of state type mixing 0rule was derived byremoving the infinite pressure boundary condition imposed by Wong and *** mixing rulewas extensively tested in terms of a comprehensive data base,consisting of 52 simple nonpolar-nonpolar,carbon dioxide containing,hydrocarbon-hydrocarbon,CFC,polar-polar,nonpolar-polarbinary and multicomponent *** on the complete predictive capability,a comparisonbetween the Wong-Sandler and the mixing rule proposed was *** results indicate that thenew mixing rule is in general superior to the Wong-Sandler’s,and the binary interaction parameteras required by the latter is removed,which reduces computing effort and is reliable in predictions ofvapor-liquid equilibria from low pressures to high pressures.

关键词： vapor-liquid equilibria equation of state mixing rule

Effect of Thermal Refining on Mechanical Properties of Annealed SAE 4130 by Multilayer GTAW

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Journal of Iron and Steel Research International 2012年第7期19卷 71-78页

作者： I k lee C L Chung y T lee y T Chien Department of Materials Science and Engineering Da-Yeh University

During the first welding process in manufacturing a precise seam container, the steel material must first undergo a full annealing treatment. Multilayer welding operations are conducted and then applied with refining treatment to obtain the goal by hardening. The influence of thermal refining on mechanical properties of annealed SAE 4130 by multilayer GTAW （gas tungsten arc welding） was discussed. The AW （annealing＋welding） and AWST （annealing＋welding＋solution＋tempering） occurred with a minimum hardness value at GGHAZ （grain growth heat affected zone） due to coarse grain growth~ the hardness occurred with sudden drops between the multilayer welding, but was still larger than the minimum value at HAZ （heat affected zone）. The welded joint efficiency of the AWST was 89.9%, with the elongation reduced to 77.2% of AST （annealing＋solution＋tempering）. The cross section of the tensile samples both appeared with a uniform dimple-shaped structure, and however the necking for AST was greater than that for AWST. The impact value for AWST was 166.5% of AST. Moreover, from microstructure observations, it was found that AWST had a greater tendency to ductile failure than AST. These results can be inferred., the process of steady pressure and the initial position of the precision tube breakage HAZ. However, when stress occurs instantly, HAZ can absorb more energy, therefore the initial damage does not occur.

关键词： thermal refining SAE 4130 multilayer welding GTAW

Gene therapy for spinal muscular atrophy:perspectives on the possibility of optimizing SMN1 delivery to correct all neurological and systemic perturbations

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Neural Regeneration Research 2025年第7期20卷 2011-2012页

作者： Sharon J.Brown Rafael J.yáñez-Muñoz Heidi R.Fuller School of Pharmacy and Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscular Disease TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and *** genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene *** was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between ***,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice ***,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.

关键词： atrophy traditionally absolute