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Nucleoside modified mRNA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord

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Neural Regeneration Research 2025年第8期20卷 2311-2312页

作者： krisztián Pajer Tamás Bellák Antal Nógrádi Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spinal cord injury and treatment opportunities:The adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular *** the spinal cord neurons have the capacity to regenerate their axons,the expression of growth inhibitory factors,lack or suppression of proper guidance cues,and profound inflammatory responses do not permit successful regeneration(khyeam et al.,2021).

关键词： injured capacity modified

Effect of graphene oxide and reduced graphene oxide nanosheets on the microstructure and mechanical properties of mild steel jointing by flux-cored arc welding

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International Journal of Minerals,Metallurgy and Materials 2020年第4期27卷 505-514页

作者： Mohammad khosravi Mohammad mansouri Ali Gholami Yadollah Yaghoubinezhad Department of Mechanical Engineering Birjand University of Technology BirjandP.O.Box 97175-569235Iran Department of Materials Engineering Birjand University of Technology BirjandP.O.Box 97175-569315Iran

The effect of graphene oxide(GO)and reduced graphene oxide(RGO)nanosheets on the microstructure and mechanical properties of welded joints of mild steel was evaluated by flux-cored arc *** was synthesized by the Hummer’s method and was reduced under hydrothermal conditions at a pressure of 1.1 MPa at 180°C for 12 h.1,3,and 10 mg/mL paste fillers were used in GO and RGO,and applied to the weld *** results clearly showed that by increasing the concentration of RGO up to 10 mg/mL,the tensile strength and hardness of the weld metal were improved by approximately 20.5%and 38.4%,respectively,because the coarse grains were changed into fine *** domain of the nanosheets cluster was 19.85×10^?9 ***,the RGO nanosheets contributed to modifying the mechanical properties of the welded steel,likely due to dislocation pinning.

关键词： graphene oxide reduced graphene oxide flux-cored arc welding steel mechanical properties

Regression analysis of squeezing-induced hybrid nanofluid flow in Darcy-Forchheimer porous medium

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 193-208页

作者： k.MUHAMMAD M.SARFRAZ Department of Humanities and Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of Mathematics Quaid-i-Azam University

This article presents a mathematical model addressing a scenario involving a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing velocity. The space between these plates contains a Darcy-Forchheimer porous medium. A mixture of water-based fluid with gold(Au) and silicon dioxide(Si O2) nanoparticles is formulated. In contrast to the conventional Fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform magnetic field is applied perpendicular to the flow direction, invoking magnetohydrodynamic(MHD) effects. Further, the model accounts for Joule heating, which is the heat generated when an electric current passes through the fluid. The problem is solved via NDSolve in MATHEMATICA. Numerical and statistical analyses are conducted to provide insights into the behavior of the nanomaterials between the parallel plates with respect to the flow, energy transport, and skin *** findings of this study have potential applications in enhancing cooling systems and optimizing thermal management strategies. It is observed that the squeezing motion generates additional pressure gradients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vigorously between the plates, increasing the flow velocity. As the fluid experiences higher flow rates due to the increased squeezing effect, it spends less time in the region between the plates. The thermal relaxation, however, abruptly changes the temperature, leading to a decrease in the temperature fluctuations.

关键词： convective boundary condition Darcy-Forchheimer medium hybrid nanofluid Joule heating magnetohydrodynamic (MHD) numerical solution squeezing flow regression analysis O361 O175.2

An Adaptive Infeasible Interior-Point Algorithm for Linear Complementarity Problems

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Journal of the Operations Research Society of China 2013年第4期1卷 523-536页

作者： Hossein mansouri Mohammad Pirhaji Department of Applied Mathematics Faculty of Mathematical SciencesShahrekord UniversityP.O.Box 115ShahrekordIran

Interior-Point Methods(IPMs)not only are the most effective methods in practice but also have polynomial-time *** researchers have proposed IPMs for Linear Optimization(LO)and achieved plentiful *** many cases these methods were extendable for LO to Linear Complementarity Problems(LCPs)*** this paper,motivated by the complexity results for linear optimization based on the study of *** et al.(mansouri and Zangiabadi in ***.62(2):285–297,2013),we extend their idea for LO to *** proposed algorithm requires two types of full-Newton steps are called,feasibility steps and(ordinary)centering steps,*** each iteration both feasibility and optimality are reduced exactly at the same *** each iteration of the algorithm we use the largest possible barrier parameter valueθwhich lies between the two values 117n and 113n,this makes the algorithm faster convergent for problems having a strictly complementarity solution.

关键词： Linear complementarity problem Infeasible-interior-point-method Central path Polynomial complexity

Effects of modified graphene oxide(GO) nanofluid on wettability and IFT changes: Experimental study for EOR applications

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Petroleum Science 2022年第4期19卷 1779-1792页

作者： Ehsan Jafarbeigi Farhad Salimi Ehsan kamari Mohsen mansouri Department of Chemical Engineering Kermanshah BranchIslamic Azad UniversityKermanshahIran Department of Petroleum Engineering Research Institute of Petroleum IndustryTehranIran Department of Chemical Engineering llam UniversityllamIran

The application of nanoparticles(NPs) in enhanced oil recovery(EOR) offers a practical approach to resolving some surface-related problems encountered in contemporary technological processes. In this study, graphene oxide nanosheets(GONs) were synthesized by Hummer's method and, then, were subjected to surface modification by hexamethyldisilazane(HMDS) and diazonium sulfonic(DS) compounds. The new combination was known as GO-Su-HMDS. The potential stability of GO-Su-HMDS nanofluids(NFs) was investigated using the zeta(ζ) potential test. A comparative study of the effect of the synthesized NFs on wettability alteration of the reservoir rock was performed using interfacial tension(IFT) and contact angle experiments. According to the results of this study, the contact angle decreased from the initial value of 161.(oil wet) to 35.(water wet). In addition, IFT decreased from18.45 mN/m for deionized(DI) water to 8.8 mN/m for 500 ppm GO-Su-HMDS NF. Moreover, the results of flooding experiments showed that the NPs of a GO-Su-HMDS concentration of 400 and 500 ppm could increase the oil recovery by 20% and 19%, respectively. The experimental results showed that GO-SuHMDS NFs with a concentration of 500 ppm have the best efficiency in terms of altering the wettability of the rock from oil wet to water wet. Thus, it can be said that this nanofluid can reduce the contact angle and IFT and also increase the sweeping efficiency of oil.

关键词： Wettability alteration Graphene oxide Contact angle Interfacial tension Zeta potential

Effects of Gibberellic Acid on Primary Terpenoids and △^9 -Tetrahydrocannabinol in Cannabis sativa at Flowering Stage

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Journal of Integrative Plant Biology 2009年第6期51卷 553-561页

作者： Hakimeh mansouri Zahra Asrar Mitra Mehrabani Faculty of Science Department of Biology Shahid Bahonar UniversityKerman Iran International Center for Science High Technology and Environmental Science(ICST)Kerman Iran Pharmacognosy Department Faculty of Pharmacy and Pharmaceutical Research Center Kerman University of Medical ScienceKerman Iran

Plants synthesize an astonishing diversity of isoprenoids, some of which play essential roles in photosynthesis, respiration, and the regulation of growth and development. Two independent pathways for the biosynthesis of isoprenoid precursors coexist within the plant cell： the cytosolic mevalonic acid （MVA） pathway and the plastidial methylerythritol phosphate （MEP） pathway. However, little is known about the effects of plant hormones on the regulation of these pathways. In the present study we investigated the effect of gibberellic acid （GA3） on changes in the amounts of many produced terpenoids and the activity of the key enzymes, 1-deoxy-D-xylulose 5-phosphate synthase （DXS） and 3-hydroxy-3-methylglutaryl coenzyme A reductase （HMGR）, in these pathways. Our results showed GA3 caused a decrease in DXS activity in both sexes that it was accompanied by a decrease in chlorophylls, carotenoids and Ag-tetrahydrocannabinol （THC） contents and an increase in α-tocopherol content. The treated plants with GA3 showed an increase in HMGR activity. This increase in HMGR activity was followed by accumulation of stigmasterol and β-sitosterol in male and female plants and campestrol in male plants. The pattern of the changes in the amounts of sterols was exactly similar to the changes in the HMGR activity. These data suggest that GA3 can probably influence the MEP and MVA pathways oppositely, with stimulatory and inhibitory effects on the produced primary terpenoids in MVA and DXS pathways, respectively.

关键词： α-tocopherol △^9 -tetrahydrocannabinol gibberellic acid phytosterols terpenoids.

Evaluation of sediment yield in PSIAC and MPSIAC models by using GIS at Toroq Watershed, Northeast of Iran

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Frontiers of Earth Science 2012年第1期6卷 83-94页

作者： Mohammad Reza mansouri Daneshvar Ali Bagherzadeh Department of Geography Mashhad Branch Islamic Azad University Mashhad Iran Department of Agriculture Mashhad Branch Islamic Azad University Mashhad Iran

Regarding the importance of watersheds in arid and semi-arid regions, it is necessary to better protect water supplies such as dam reservoirs. The most efficient way of conserving water sources is to apply proper management to decrease erosion and sedimentation. The first step of this process is to be aware of sediment yield （Qs）/production and identify erosive zones in upper reach of reservoirs. The present study aims to evaluate Qs and production in Pacific Southwest Inter-Agency Committee （PSIAC） and mod- ified PSIAC （MPSIAC） models by using satellite data, GIS analysis, and field observations. According to the results, the study area can be categorized into five erosive classes： very high, high, moderate, low and negligible. The east part of the watershed is slightly eroded due to its hard surface geology and relatively flat topography characteristics, while the northern and southern parts of the basin are highly eroded because of the high erodibility potential of soil and intensive cultivation of the area. A comparison of the output maps from PSIAC and MPSIAC models showed that the calculated Qs in most parts correspond well in both models and with field observa- tions. The results of regression between main determining factors （surface geology, soil, topography and land cover） and Qs derived from each model indicated moderate to strong correlation coefficient （R2 = 0.436-0.996 to 0.893- 0.998） after PSIAC and MPSIAC models, respec- tively.

关键词： evaluation of sediment yield (Qs) erodiblefactors Pacific Southwest Inter-Agency Committee(PSIAC) and modified PSIAC (MPSIAC) models sedimentproduction GIS Toroq Watershed Northeast of Iran

Hierarchical data replication strategy to improve performance in cloud computing

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Frontiers of Computer Science 2021年第2期15卷 63-79页

作者： Najme mansouri Mohammad Masoud JAVIDI Behnam Mohammad Hasani ZADE Department of Computer Science Shahid Bahonar University of KermanKerman76169-14111Iran Mahani Mathematical Research Center Shahid Bahonar University of KermanKerman76169-14111Iran

Cloud computing environment is getting more interesting as a new trend of data *** replication has been widely applied to improve data access in distributed systems such as Grid and ***,due to the finite storage capacity of each site,copies that are useful for future jobs can be wastefully deleted and replaced with less valuable ***,it is considerable to have appropriate replication strategy that can dynamically store the replicas while satisfying quality of service(QoS)requirements and storage capacity *** this paper,we present a dynamic replication algorithm,named hierarchical data replication strategy(HDRS).HDRS consists of the replica creation that can adaptively increase replicas based on exponential growth or decay rate,the replica placement according to the access load and labeling technique,and finally the replica replacement based on the value of file in the *** evaluate different dynamic data replication methods using CloudSim *** demonstrate that HDRS can reduce response time and bandwidth usage compared with other *** means that the HDRS can determine a popular file and replicates it to the best *** method avoids useless replications and decreases access latency by balancing the load of sites.

关键词： cloud computing data replication multi-tier architecture simulation load balance

Walk-off reduction,using an external optical plate and Bessel-Gaussian interaction

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Chinese Physics B 2015年第2期24卷 215-222页

作者： Masoume mansouri Mohsen Askarbioki Saeed Ghavami Sabouri Alireza khorsandi Department of Physics University of Isfahan

To reduce the walk-off angle of the extraordinary third-harmonic ultraviolet wave at 355 nm generated by type ⅡkTiOPO4 and type I β-BaB2O4 optical crystals,and the Gaussian output beam of a Q-switched Nd：YAG laser,a simple theoretical model was developed based on a rotatable Bk7 plate of variable *** rotating the plate up to 35°along the beam direction,we reduced the walk-off angle up to ~ 13%.The same phenomenon is predicted by the model,confirming the performance of the *** is found that,due to the walk-off effect,the intensity profile of the thirdharmonic generation beam is slightly *** compensate for the observed phenomena and further reduce the walkoff,we used a combination of a convex lens and an axicon to transform the beam profile of the interacting fundamental and second-harmonic generation waves to the zero-order Bessel-Gaussian *** a result,the walk-off is decreased to~ 48.81 mrad,providing ~ 30%relative *** using the same Bk7 plate rotated up to 35° along the third-harmonic beam direction,the walk-off angle is further reduced to 38.9 ***,it is observed that the beam profile of the emerged Bessel-Gaussian third-harmonic generation beam remains unchanged with no degradation.

关键词： Bessel-Gaussian beam walk-off third-harmonic generation