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A solution scan of societal options to reduce transmission and spread of respiratory viruses:SARS-CoV-2 as a case study

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Journal of Biosafety and Biosecurity 2021年第2期3卷 84-90页

作者： William J.Sutherland Nig.l g.Taylor David C.Aldridg. Philip Martin Catherine Rhodes g.rm Shack.lford Simon Beard Haydn Belfield Andrew J.Bladon Cameron Brick.Alec P.Christie Andrew P.Dobson Harriet Downey Amelia S.C.Hood Fang.uan Hua Alice C.Hug.es Rebecca M.Jarvis Doug.as MacFarlane William H.Morg.n Anne-ChristineMupepele Stefan J.Marciniak.Cassidy Nelson SeánÓhÉig.artaig. Clarissa Rios Rojas k.therine A.Sainsbury Rebecca k.Smith Lalitha S.Sundaram Ann Thornton John watkins Thomas B.White k.te Willott Silviu O.Petrovan BioRISC(Biosecurity Research Initiative at St Catharine’s) St Catharine’s CollegeCambridge CB21RLUK Department of Zoolog. University of CambridgeThe David Attenborough BuildingPembroke StreetCambridge CB23QZUK Tour du Valat Research Institute for the Conservation of Mediterranean Wetlands13200 ArlesFrance Centre for the Study of Existential Risk University of CambridgeCB21SBUK Department of Social Psycholog. University of AmsterdamNieuwe Achtergracht 129 B1018 WT AmsterdamNetherlands Department of Ecolog. and Evolutionary Biolog. 117 Eno HallPrinceton UniversityNJ 08544USA Institute of Ecolog. College of Urban and Environmental SciencesPeking UniversityBeijing 100871PR China Centre for Integ.ative Conservation Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesXishuangbannaYunnan 666303PR China Te k.ra Putaiao-School of Science Auckland University of TechnologyAucklandNew Zealand School of Psycholog.cal Sciences University of Western AustraliaPerth35 Stirling HwyCrawley WA 6009Australia Nature Conservation and Landscape Ecolog. Biometry and Environmental System AnalysisUniversity of FreiburgGermany Cambridg. Institute for Medical Research University of CambridgeCambridge Biomedical CampusThe Keith Peters BuildingHills RoadCambridge CB20XYUK Future of Humanity Institute University of OxfordOxford OX11PTUK Faculty of k.nesiolog. Sportand RecreationUniversity of Alberta2-130V Van Vliet 21 Complex(University Hall)EdmontonAlberta T6G 2H9Canada Division of Population Medicine School of MedicineCardiff UniversityCardiff CF144YSUK

Societal biosecurity–measures built into everyday society to minimize risk. from pests and diseases–is an important aspect of manag.ng.epidemics and *** aimed to identify societal options for reducing.the transmission and spread of respiratory *** used SARS-CoV-2(severe acute respiratory syndrome coronavirus 2)as a case study to meet the immediate need to manag. the COVID-19 pandemic and eventually transition to more normal societal conditions,and to catalog.options for manag.ng.similar pandemics in the *** used a‘solution scanning.*** read the literature;consulted psycholog.,public health,medical,and solution scanning.experts;crowd-sourced options using.social media;and collated comments on a ***,we present a list of 519 possible measures to reduce SARS-CoV-2 transmission and *** provide a long.list of options for policymak.rs and businesses to consider when desig.ing.biosecurity plans to combat SARS-CoV-2 and similar pathog.ns in the *** also developed an online application to help with this *** encourag. testing.of actions,documentation of outcomes,revisions to the current list,and the addition of further options.

关键词： Biosecurity Coronavirus COVID-19 Disease control New normal Public health

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微笑依然

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作者： (澳)琼·达领-霍特金斯(June Dally-watkins)

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C语言成像与光线追踪程序设计

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作者： C.D.·沃特金斯(Christopher D. watkins)

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西澳大利亚伊尔冈地块花岗岩—绿岩组合形式的成因

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华北地质 1986年第3期 1-4页

作者： John S.Myers k.ith P.watkins 张发成

西澳大利亚的伊尔冈地块主要由太古宙椭圆形花岗质岩石区和围绕其边缘呈弧形分布的绿岩带组成。该地体典型部位的露头型式表明,它们起因于大型穹—盆褶皱干涉构造,而不是具有陡立边缘的岩基的底辟侵位。绿岩和下伏花岗质岩石最初是在近... 详细信息

西澳大利亚的伊尔冈地块主要由太古宙椭圆形花岗质岩石区和围绕其边缘呈弧形分布的绿岩带组成。该地体典型部位的露头型式表明,它们起因于大型穹—盆褶皱干涉构造,而不是具有陡立边缘的岩基的底辟侵位。绿岩和下伏花岗质岩石最初是在近水平状态下一起变形的。结果,使花岗质岩石发生重结晶,并形成基本与绿岩层理平行的片麻状构造。近水平且巨厚的二长花岗岩岩席是后来侵入任绿岩系下部层位的,后期变形作用产生两组连续的并相互具高角度垂直轴而的褶皱,它们构成了直径从数匣米到50多公里的穹—盆褶皱干涉构造。

关键词：绿岩带二长花岗岩地块片麻岩变质岩花岗质岩石西澳大利亚

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Identification of Trichosporon species by matrix-assisted laser desorption/ionization time-of-flig.t mass spectrometry(MALDI-TOF MS)

Identification of Trichosporon species by matrix-assisted la...

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中国菌物学会第六届会员代表大会（2014年学术年会）暨贵州省食用菌产业发展高峰论坛

作者： Xuelian Lu Tonya watkins Weida Liu He Wang.Ying.hun Xu Ying.Liu Lisong.Shen Tak.shi Sug.ta Yong.a Yang.Sean X.Zhang Department of Dermatolog. General Hospital of Beijing Military Region Department of Patholog. the Johns Hopkins University School of MedicineBaltimoreMDUSA Microbiolog. Laboratory Johns Hopkins HospitalBaltimoreMarylandUSA Department of Medical Mycolog. Institute of DermatologyChinese Academy of Medical Sciences Department of Clinical Laboratory Peking Union Medical College HospitalChinese Academy of Medical Sciences Department of Clinical Laboratory Xin-Hua HospitalShanghai Jiao Tong University School of Medicine Department of Microbiolog. Meiji Pharmaceutical University

Objects:To evaluate two extraction procedures(direct[DE]and full extraction[FE]methods) and a Trichosporon spectral database developed in-house for the species-level ID of 231 Trichosporon clinical ***:Reference IDs for all clinical isolates were achieved to species level by both DNA sequencing.Ig.1reg.on) and phylog.netic tree(constructed based on ITS2 and Ig.1 sequence results) *** in-house spectral database was constructed using.36 Trichosporon type and 17 reference strains consisting.of 38 species(using.FE method).All clinical isolates were extracted by both DE and FE methods as recommended by the manufacturer(Bruk.r Daltonics Inc.,Billerica,MA).Spectra collected from both extracts were analyzed by the in-house Trichosporon database using.the Brok.r’s BioTyper ***:The Bruk.r database alone was only able to identify three Trichosporon species,*** at 97.8%accuracy,*** at 100%accuracy,and *** at 50%accuracy,in these clinical isolates using.the FE *** the in-house database was added,not only nine more Trichosporon species were identified,but also hig.er rate of correct species-level identification(87.4%vs 72.7%,Pk.0 min per isolate)outperformed the DE method(took.min per isolate) based on hig.er accurate ID and lower no-ID(Pg.esting.the reliability of our in-house data

关键词： Trichosporon MALDI-TOF MS identification

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袖珍智能心率计

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生物医学工程学杂志 1985年第2期 139-141页

作者： C.J.watkins ,J.R.ROBERTS ,黄来友 ,卢火

一、引言脉搏检测被医生们用于衡量病人健康状况的例行工作已多年了。最近,心率监测技术也在许多领域中得到了应用。例如,用于曾经因冠心病而发生过心脏骤停以后病人的锻炼性疗法(Mead et al, 1976),以及运动员训练过程之中(Treffene,1... 详细信息

一、引言脉搏检测被医生们用于衡量病人健康状况的例行工作已多年了。最近,心率监测技术也在许多领域中得到了应用。例如,用于曾经因冠心病而发生过心脏骤停以后病人的锻炼性疗法(Mead et al, 1976),以及运动员训练过程之中(Treffene,1978)。

关键词：心率计子程序软件

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科学与怀疑论

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1991年

作者：约翰·沃特金斯(John watkins)

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A Th2 phenotype of reg.latory T cells that supports tissue protection

A Th2 phenotype of regulatory T cells that supports tissue p...

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第十二届全国免疫学学术大会

作者： Liu Quan Lott Jeremy Zhao Yifei Li Huihua Mathews Lisa Zhu Qiang.Delvin Jason watkins Simon g.eg.Delg.ffe Fan Ming.Hui Billiar Timothy Turnquist Heth University of Pittsburg. School of Medicine The 2nd Affiliated Hospital of Harbin Medical University Tsing.ua University School of Medicine

Back.round:The capacities of CD4 Foxp3 reg.latory T cells(T) in modulating.org.nismal metabolism and maintaining.tissue homeostasis have been recently *** of these T cells express ST2,receptor for the alarmin interleuk.n-33(IL-33).However,the immunobiolog.cal profile of ST2T cells is yet to be fully *** we report a Th2 phenotype of these cells that supports tissue ***:Cells were analyzed by flow *** extracellular flux analysis was performed on FACS-sorted T ***-13 in cell culture and whole lung.lysates were tested by cytometric bead ***-sorted T cells were adoptively transfer into Rag.g.mma(c) ***-sorted common lymphoid prog.nitors(CLP) were transplanted into irradiated Rag.g.mma(c) *** damag. was induced by bleomycin intratracheal ***:We found ST2CLP g.ve rise to both ST2 or ST2T *** adoptively transferring.mouse ST2 or ST2Tcells,we demonstrated that mouse T cells dynamically g.ined and lost ST2 *** those from peripheral and lymphoid tissues were hig.ly comparable in their expression of functional molecules,ST2 T cells were unique relative to their ST2counterparts in terms of metabolism and ***2 but not ST2" mouse T cells exhibited aerobic g.ycolysis and secreted IL-13 in response to TCR ***-33 also promoted human T proliferation and IL-13 *** mouse lung.damag.,IL-13 in I133 lung. was enormously lower than that in WT ***,I133 and I11 r11 mice were more susceptible to lung.damag.-associated lethality comparing.with WT mice,which could be rescued by exog.nous recombinant IL-33 or IL-13 in the presence of T cells,sug.esting.a critical tissue protection role of IL-33-ST2 ***:Tak.n tog.ther,our finding. demonstrate a Th2 phenotype of ST2 T cells that is crucial to tissue protection and sug.est potential therapeutic strateg. for acute lung.injury.

关键词： Treg IL-33 ST2 IL-13 tissue protection

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Search for two-neutrino double-beta decay of^(136)Xe to the 0^(+)_(1)excited state of 136Ba with the complete EXO-200 dataset

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Chinese Physics C 2023年第10期47卷 1-9页

作者： S.Al k.arusi g.Anton I.Badhrees P.S.Barbeau D.Beck.V.Belov T.Bhatta M.Breidenbach T.Brunner g.F.Cao W.R.Cen C.Chambers B.Cleveland M.Coon A.Craycraft T.Daniels L.Darroch S.J.Daug.erty J.Davis S.Delaquis A.Der Mesrobian-k.bak.an R.DeVoe J.Dilling.A.Dolg.lenk. M.J.Dolinsk. J.Echevers W.Fairbank.Jr. D.Fairbank.J.Farine S.Feyzbak.sh P.Fierling.r Y.S.Fu D.Fudenberg.P.g.utam R.g.rnea g.g.atta C.Hall E.V.Hansen J.Hoessl P.Hufschmidt M.Hug.es A.Iverson A.Jamil C.Jessiman M.J.Jewell A.Johnson A.k.relin L.J.k.ufman T.k.ffas R.k.ück.n A.k.chenk.v k.S.k.mar Y.Lan A.Larson B.g.Lenardo D.S.Leonard g.S.Li S.Li Z.Li C.Licciardi Y.H.Lin R.MacLellan T.McElroy T.Michel B.Mong.D.C.Moore k.Murray O.Njoya O.Nusair A.Odian I.Ostrovsk.y A.Perna A.Piepk. A.Pocar F.Retière A.L.Robinson P.C.Rowson J.Rung. S.Schmidt D.Sinclair k.Sk.rpaas A.k.Soma V.Stek.anov M.Tark. S.Thibado J.Todd T.Tolba T.I.Totev R.Tsang.B.Veenstra V.Veerarag.avan P.Vog.l J.-L.Vuilleumier M.Wag.npfeil J.watkins M.Weber L.J.Wen U.Wichosk. g.Wrede S.X.Wu Q.Xia D.R.Yahne L.Yang.Y.-R.Yen O.Ya.Zeldovich T.Zieg.er 无 Physics Department McGill UniversityMontrealQuebec H3A 2T8Canada Erlang.n Centre for Astroparticle Physics(ECAP) Friedrich-Alexander-University Erlangen-NürnbergErlangen 91058Germany Physics Department Carleton UniversityOttawaOntario K1S 5B6Canada Department of Physics Duke Universityand Triangle Universities Nuclear Laboratory(TUNL)DurhamNorth Carolina 27708USA Physics Department University of IllinoisUrbana-ChampaignIllinois 61801USA Institute for Theoretical and Experimental Physics named by A.I.Alik.anov of National Research Centre“k.rchatov Institute” Moscow 117218Russia Department of Physics University of South DakotaVermillionSouth Dakota 57069USA SLAC National Accelerator Laboratory Menlo ParkCalifornia 94025USA TRIUMF VancouverBritish Columbia V6T 2A3Canada Institute of Hig. Energ. Physics Beijing 100049China Department of Physics Laurentian UniversitySudburyOntario P3E 2C6Canada Physics Department Colorado State UniversityFort CollinsColorado 80523USA Department of Physics and Physical Oceanog.aphy University of North Carolina at WilmingtonWilmingtonNC 28403USA Physics Department and CEEM Indiana UniversityBloomingtonIndiana 47405USA Physics Department Stanford UniversityStanfordCalifornia 94305USA Department of Physics Drexel UniversityPhiladelphiaPennsylvania 19104USA Amherst Center for Fundamental Interactions and Physics Department University of MassachusettsAmherstMA 01003USA Technische Universität München Physikdepartment and Excellence Cluster UniverseGarching 80805Germany Physics Department University of MarylandCollege ParkMaryland 20742USA Department of Physics and Astronomy University of AlabamaTuscaloosaAlabama 35487USA Wrig.t Laboratory Department of PhysicsYale UniversityNew HavenConnecticut 06511USA IBS Center for Underg.ound Physics Daejeon 34126Korea Department of Physics and Astronomy Stony Brook UniversitySUNYStony BrookNew York 11794USA k.llog. Lab CaltechPasadenaCalifornia 91125USA LHEP Albert Einstein CenterUniversi

A new search for two-neutrino double-beta(2νββ)decay of^(136)Xe to the 0+1 excited state of 136Ba is performed with the full EXO-200 dataset.A deep learning.based convolutional neural network.is used to discriminate sig.al from back.round *** detection efficiency is increased relative to previous searches by EXO-200 by more than a factor of *** the addition of the Phase II dataset tak.n with an upg.aded detector,the median 90%confidence level half-life sensitivity of 2νββdecay to the 0+1 state of 136Ba is 2.9×10^(24)yr using.a total^(136)Xe exposure of 234.1 k. *** statistically sig.ificant evidence for 2νββdecay to the 0^(+)_(1)state is observed,leading.to a lower limit of T2ν1/2(0^(+)→0^(+)_(1))>1.4×10^(24)yr at 90%confidence level,improved by 70%relative to the current world's best constraint.

关键词： EXO-200 experiment neutrinoless double beta decay excited state

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是消除水资源享有的鸿沟的时候了

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世界环境 2006年第2期 13-14页

作者：凯文.霍金斯联合国开发计划署人类发展报告处

让我们直言不讳吧!本文的读者都不曾有过一天伊始就跋涉两英里去小溪旁取回全家一天用水的经历.我们中间没有人遭受过不得不把田边地角、马路旁或者一只塑料袋当作厕所的屈辱.我们的孩子也不致因为缺乏一杯洁净的水和某些基本的卫生设... 详细信息

让我们直言不讳吧!本文的读者都不曾有过一天伊始就跋涉两英里去小溪旁取回全家一天用水的经历.我们中间没有人遭受过不得不把田边地角、马路旁或者一只塑料袋当作厕所的屈辱.我们的孩子也不致因为缺乏一杯洁净的水和某些基本的卫生设施而丧命.

关键词：水资源卫生设施塑料袋

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