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Study of the pressure transient behavior of directional wells considering the effect of non-uniform flux distribution

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Petroleum Science 2024年第3期21卷 1765-1779页

作者： Yan-Zhong Liang Bai-Lu teng Wan-jing Luo School of Energy Resources China University of Geosciences(Beijing)Beijing100083China

During the production,the fluid in the vicinity of the directional well enters the wellbore with different rates,leading to non-uniform flux distribution along the directional ***,in all existing studies,it is oversimplified to a uniform flux distribution,which can result in inaccurate results for field ***,this paper proposes a semi-analytical model of a directional well based on the assumption of non-uniform flux ***,the direction well is discretized into a carefully chosen series of linear sources,such that the complex well trajectory can be captured and the nonuniform flux distribution along the wellbore can be considered to model the three-dimensional flow *** using the finite difference method,we can obtain the numerical solutions of the transient flow within the *** the aid of Green's function method,we can obtain the analytical solutions of the transient flow from the matrix to the *** complete flow behavior of a directional well is perfectly represented by coupling the above two types of transient ***,on the basis of the proposed model,we conduct a comprehensive analysis of the pressure transient behavior of a directional *** computation results show that the flux variation along the direction well has a significant effect on pressure *** addition,the directional well in an infinite reservoir may exhibit the following flow regimes:wellbore afterflow,transition flow,inclined radial flow,elliptical flow,horizontal linear flow,and horizontal radial *** horizontal linear flow can be observed only if the formation thickness is much smaller than the well ***,a dip region that appears on the pressure derivative curve indicates the three-dimensional flow behavior near the wellbore.

关键词： Directional well Pressure transient behavior Semi-analytical model Non-uniform flux

The role of exosomes in adult neurogenesis:implications for neurodegenerative diseases

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Neural Regeneration Research 2024年第2期19卷 282-288页

作者： Zhuoyang Yu Yan teng jing Yang Lu Yang Institute of Neurology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Laboratory of Aging Research School of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina

Exosomes are cup-shaped extracellular vesicles with a lipid bilayer that is approximately 30 to 200 nm in *** are widely distributed in a range of body fluids,including urine,blood,milk,and *** exert biological function by transporting factors between different cells and by regulating biological pathways in recipient *** an important form of intercellular communication,exosomes are increasingly being investigated due to their ability to transfer bioactive molecules such as lipids,proteins,mRNAs,and microRNAs between cells,and because they can regulate physiological and pathological processes in the central nervous *** neurogenesis is a multistage process by which new neurons are generated and migrate to be integrated into existing neuronal *** the adult brain,neurogenesis is mainly localized in two specialized niches:the subventricular zone adjacent to the lateral ventricles and the subgranular zone of the dentate *** increasing body of evidence indicates that adult neurogenesis is tightly controlled by environmental conditions with the *** recent studies,exosomes released from different sources of cells were shown to play an active role in regulating neurogenesis both in vitro and in vivo,thereby participating in the progression of neurodegenerative disorders in patients and in various disease ***,we provide a state-of-the-art synopsis of existing research that aimed to identify the diverse components of exosome cargoes and elucidate the therapeutic potential of exosomal contents in the regulation of neurogenesis in several neurodegenerative *** emphasize that exosomal cargoes could serve as a potential biomarker to monitor functional neurogenesis in *** addition,exosomes can also be considered as a novel therapeutic approach to treat various neurodegenerative disorders by improving endogenous neurogenesis to mitigate neuronal loss in the central nervous system.

关键词： adult neurogenesis Alzheimer’s disease amyotrophic lateral sclerosis exosome Huntington’s disease neurodegenerative disease neurogenic niches Parkinson’s disease

Comparison of the Rose Bengal Plate and the Complement Fixation Tests with the Tube Agglutination Test for Diagnosis of Human Brucellosis

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Open Journal of Clinical Diagnostics 2017年第3期7卷 73-82页

作者： Ying-Hock teng jung-jing teng Samantha Chao Hsu Chao Suryakant D. Waghela Department of Emergency Medicine School of Medicine Chung Shan Medical University Taiwan Department of Emergency Medicine Chung Shan Medical University Hospital Taiwan Residency Program Civil Aviation General Hospital Peking University Health Science Center Beijing China Rice University Houston TX USA HGSC Baylor College of Medicine Houston TX USA Veterinary Research Laboratory Kabete Kenya Department of Veterinary Pathobiology Texas A&M University College Station TX USA

Brucellosis is a zoonotic disease of economic importance. The clinical manifestations vary in humans;therefore a good diagnostic test is required to confirm the disease. The serum tube agglutination (SA) test, though still the most widely test used, can be problematic for the diagnosis of chronic infections. The other supplementary tests, such as the complement fixation (CF) test and ELISA, require special equipment, reagents and trained personnel. The Rose Bengal plate (RBP) test has shown potential as a good rapid diagnostic test. This is a report of serum samples from suspected cases of brucellosis that were tested using the RBP, SA and CF tests. The RBP test was shown to have a better relative sensitivity and as good specificity as the SA when compared with the CF test, and may be a useful initial diagnostic test for hospitals in remote rural areas if properly conducted with well stored antigen.

关键词： Brucellosis Human Diagnosis Rose Bengal Plate Test

Robust multi-sensor image matching based on normalized self-similarity region descriptor

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Chinese Journal of Aeronautics 2024年第1期37卷 271-286页

作者： Xuecong LIU Xichao teng jing LUO Zhang LI Qifeng YU Yijie BIAN College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073China High-Tech Institute Qingzhou 262500China

Multi-modal image matching is crucial in aerospace applications because it can fully exploit the complementary and valuable information contained in the amount and diversity of remote sensing ***,it remains a challenging task due to significant non-linear radiometric,geometric differences,and noise across different *** improve the performance of heterologous image matching,this paper proposes a normalized self-similarity region descriptor to extract consistent structural *** first construct the pointwise self-similarity region descriptor based on the Euclidean distance between adjacent image blocks to reflect the structural properties of multi-modal ***,a linear normalization approach is used to form Modality Independent Region Descriptor(MIRD),which can effectively distinguish structural features such as points,lines,corners,and flat between multi-modal *** further improve the matching accuracy,the included angle cosine similarity metric is adopted to exploit the directional vector information of multi-dimensional feature *** experimental results show that the proposed MIRD has better matching accuracy and robustness for various multi-modal image matching than the state-of-the-art *** can effectively extract consistent geometric structure features and suppress the influence of SAR speckle noise using non-local neighboring image blocks operation,effectively applied to various multi-modal image matching.

关键词： Remote sensing Multi-modal image matching Template matching Feature descriptor Similarity metric Synthetic Aperture Radar(SAR)

X-ray excited Mn^(2+)-doped persistent luminescence materials with biological window emission for in vivo bioimaging

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Journal of Rare Earths 2024年第1期42卷 28-35,I0001页

作者： Hanrun Zheng Lin Liu Yi’ang Li Rui Rong Liang Song Junpeng Shi jing teng Xia Sun Yun Zhang State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou350002China University of the Chinese Academy of Sciences Beijing100049China Xiamen Hospital of Traditional Chinese Medicine Xiamen361015China Fujian Science and Technology Innovation Laboratory for Optoelectronic Information of China Fuzhou350108China

In recent years,persistent luminescence materials(PLMs)excited by X-rays and emitting in biological windows have received extensive attention in the field of high-sensitivity *** metal Mn^(2+)is an ideal emission center,but few studies focus on Mn^(2+)-doped PLMs with X-ray excitation and biological window ***,we report a Mn^(2+)-doped PLM,LiYGeO_(4):Mn^(2+)(LYGM),with excellent biological window persistent luminescence *** excitation by UV,LYGM produces a durable biological window of persistent luminescence emission at 660 nm for up to 20 *** *** can be repeatedly excited by X-rays,resulting in long-term biological window persistent luminescence *** addition,we obtain LYGM around 200 nm in diameter by ball milling and centrifugation and improve its biocompatibility by surface modification to apply it to in vivo imaging in *** LYGM are injected into mice through the tail vein,in situ excitation of X-rays can be *** the persistent luminescence decays,LYGM can be re-excited for repeated ***,LYGM shows potential prospects for in vivo deep tissue and long-term bioimaging.

关键词： Persistent luminescence X-ray Biological window In vivo imaging Rare earths

Cell Wall Fixation,Translocation,and Vacuolar Detoxification of Cadmium Contribute to Differential Grain Cadmium Accumulation in Two Rice Cultivars

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Rice science 2024年第3期31卷 241-244,I0008-I0010页

作者： ZHU Xiaofang ZHAO Ling HUANG jing HE Jiatong SONG Jiayin teng Ying SHEN Renfang State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of ScienceNanjing 210008China State Key Laboratory of Subtropical Silviculture Zhejiang A&F UniversityHangzhou 311300China

Cadmium(Cd)toxicity in rice is a major concern for human health and the environment,as it can accumulate in rice grains when grown in Cd-contaminated *** mitigate the risk of Cd toxicity,it is crucial to cultivate rice varieties with low grain Cd *** the summers of 2021 and 2022,we conducted Cd analysis on two rice cultivars,Tianyouhuazhan(TYHZ)and Xiushui 14,grown in fields with varying Cd pollution *** cultivars were also subjected to hydroponic treatment with or without 1μmol/L Cd for 7 d to assess Cd accumulation,nitric oxide(NO)production。

关键词： cultivar soils pollution

Microstructure development of Ti scaffold by laser powder bed fusion with chemical polishing and its mechanical properties, biocompatibility

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BIOSURFACE AND BIOTRIBOLOGY 2024年第2期10卷 52-62页

作者： Lu, Changfu Chen, jing Ma, teng Chen, Yuxin Zeng, Da Gan, Yiliang Yang, Youwen Double Med Technol Inc Xiamen Peoples R China Jiangxi Univ Sci & Technol Inst Addit Mfg Nanchang Peoples R China Tongling Univ Key Lab Construct Hydraul Robots Anhui Higher Educ Tongling Peoples R China Nanjing Univ Coll Engn & Appl Sci Nanjing Peoples R China

Titanium (Ti) dental scaffolds are widely used in dental prosthetics due to their excellent mechanical properties and biocompatibility. However, conventional Ti scaffolds manufactured through machining often do not fit perfectly with the bone defect site. Laser powder bed fusion (LPBF) technology enables the personalised manufacturing of custom-made Ti scaffolds. A custom-made Ti scaffold was prepared using LPBF and its surface roughness was improved through chemical polishing. To enhance the surface roughness, a nitric acid mixed solution with a specific composition of HF: HNO3:C3H6O3 = 2:2:3 was used. The polishing mechanism was investigated by adjusting the F/Ti ratio to control the formation and dissolution of the oxide film. As a result, the surface of the Ti scaffold after polishing exhibited a smooth and flat appearance compared to the LPBF part, with a reduced surface roughness (Ra) of 1.23 +/- 0.19 mu m. The custom-made Ti scaffold also demonstrated favourable mechanical properties, with a bending strength of 335.18 +/- 33.62 MPa and stiffness of 2.13 +/- 0.21 GPa. Furthermore, in vitro cell tests confirmed the excellent biocompatibility of the custom-made Ti scaffold. The authors present a feasible strategy for the further clinical application of custom-made Ti scaffolds, offering enhanced surface properties and addressing the limitations of conventional machining methods.

关键词： additive manufacturing dental material property surface roughness GUIDED BONE REGENERATION ALLOY OPTIMIZATION PARAMETERS MEMBRANE BEHAVIOR

Simulated Indonesian Throughflow in Makassar Strait across the SODA3 products

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Acta Oceanologica Sinica 2024年第1期43卷 80-98页

作者： tengfei Xu Zexun Wei Haifeng Zhao Sheng Guan Shujiang Li Guanlin Wang Fei teng Yongchui Zhang jing Wang First Institute of Oceanography/Key Laboratory of Marine Science and Numerical Modeling Ministry of Natural ResourcesQingdao 266061China Laboratory for Regional Oceanography and Numerical Modeling Qingdao Marine Science and Technology CenterQingdao 266237China College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410073China CAS Key Laboratory of Ocean Circulation and Waves Center for Ocean Mega-ScienceInstitute of OceanologyChinese Academy of ScienceQingdao 266071China

The Indonesian Throughflow(ITF), which connects the tropical Pacific and Indian oceans, plays important roles in the inter-ocean water exchange and regional or even global climate variability. The Makassar Strait is the main inflow passage of the ITF, carrying about 77% of the total ITF volume transport. In this study, we analyze the simulated ITF in the Makassar Strait in the Simple Ocean Data Assimilation version 3(SODA3) datasets. A total of nine ensemble members of the SODA3 datasets, of which are driven by different surface forcings and bulk formulas, and with or without data assimilation, are used in this study. The annual mean water transports(i.e.,volume, heat and freshwater) are related to the combination of surface forcing and bulk formula, as well as whether data assimilation is employed. The phases of the seasonal and interannual variability in water transports cross the Makassar Strait, are basically consistent with each other among the SODA3 ensemble members. The interannual variability in Makassar Strait volume and heat transports are significantly correlated with El Ni?oSouthern Oscillation(ENSO) at time lags of-6 to 7 months. There is no statistically significant correlation between the freshwater transport and the ENSO. The Makassar Strait water transports are not significantly correlated with the Indian Ocean Dipole(IOD), which may attribute to model deficiency in simulating the propagation of semiannual Kelvin waves from the Indian Ocean to the Makassar Strait.

关键词： Indonesian Throughflow Simple Ocean Data Assimilation(SODA) El Ni?o-Southern Oscillation(ENSO) Indian Ocean Dipole(IOD) data assimilation

Natural rubber latex as a potential additive for water-based drilling fluids

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Petroleum Science 2024年第4期21卷 2677-2687页

作者： Jun Yang Guan-Cheng Jiang jing-Tian Yi Yin-Bo He Li-Li Yang teng-Fei Dong Guo-Shuai Wang College of Petroleum Engineering China University of Petroleum (Beijing) National Engineering Research Center of Oil & Gas Drilling and Completion Technology Changqing Drilling General Company CNPC Chuanqing Drilling Engineering Company Limited

The environmental hazards and "carbon footprint" of oil and gas drilling can be significantly reduced by replacing traditional petroleum-based chemical additives with natural materials derived from plants and animals. This paper explored for the first time the interaction mechanism between natural rubber latex(NRL) and bentonite suspensions(BTs) through a series of characterization experiments, as well as the potential applications in water-based drilling fluids(WBDF). The gel viscoelasticity experiments showed that NRL could decrease the consistency coefficient(k) and flow index(n) of BTs, and enhance the shear thinning performance of BTs as pseudo-plastic fluids. In addition, 0.5 w/v% NRL not only increased the critical yield stress and strengthened the structural strength between the bentonite particles, but also facilitated the compatibility of pressure loss and flow efficiency. The evaluation of colloidal stability and WBDF performance indicated that NRL particles could promote the hydration and charge stability on the surface of BTs particles, and optimize the particle size distribution and flow resistance of WBDF under the "intercalation-exfoliation-encapsulation" synergistic interaction. Moreover, NRL can improve the rheological properties of WBDF at high temperatures(<150.C), and form a dense blocking layer by bridging and sealing the pores and cracks of the filter cake, which ultimately reduces the permeability of the cake and the filtration loss of WBDF.

关键词： Natural materials Water-based drilling fluids Natural rubber latex Bentonite suspensions Filtration loss