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Journal of Integrative Plant Biology 2011年第1期53卷 63-73页

作者： Kyaw Thu Moe Jong-Wook Chung Young-il Cho jung-Kyung Moon Ja-Hwan Ku Jin-Kyo jung jungran lee Yong-Jin Park Department of Plant Resources College of Industrial SciencesKongju National University The Rural Development Administration(RDA) Legume Bio-Resource Center of Green Manure(LBRCGM) Kongju National University

Mungbean （Vigna radiata （L.） Wilczek） is a unique species in its ability to fix atmospheric nitrogen, with early maturity, and relatively good drought resistance. We used 454 sequencing technology for transcriptome sequencing. A total of 150 159 and 142 993 reads produced 5 254 and 6 374 large contigs （〉_500 bp） with an average length of 833 and 853 for Sunhwa and Jangan, respectively. Functional annotation to known sequences yielded 41.34% and 41.74% unigenes for Jangan and Sunhwa. A higher number of simple sequence repeat （SSR） motifs was identified in Jangan （1 630） compared with that of Sunhwa （1 334）. A similar SSR distribution pattern was observed in both varieties. A total of 8 249 single nucleotide polymorphisms （SNPs） and indels with 2 098 high-confidence candidates were identified in the two mungbean varieties. The average distance between individual SNPs was -860 bp. Our report demonstrates the utility of transcriptomic data for implementing a functional annotation and development of genetic markers. We also provide large resource sequence data for mungbean improvement programs.

关键词： Sequence Information on Simple Sequence Repeats and Single Nucleotide Polymorphisms through Transcriptome Analysis of Mungbean SNPs

Flash‑Induced High‑Throughput Porous Graphene via Synergistic Photo‑Effects for Electromagnetic Interference Shielding

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Nano-Micro Letters 2023年第11期15卷 1-18页

作者： Jin Soo lee Jeong‑Wook Kim Jae Hee lee Yong Koo Son Young Bin Kim Kyoohee Woo Chanhee lee il‑Doo Kim Jae Young Seok Jong Won Yu jung Hwan Park Keon Jae lee Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak‑roYuseong‑guDaejeon 34141Republic of Korea School of Electrical Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak‑roYuseong‑guDaejeon 34141Republic of Korea Department of Printed Electronics Nano‑Convergence Manufacturing Systems Research DivisionKorea Institute of Machinery and Materials(KIMM)156 Gajeongbuk‑RoYuseong‑GuDaejeon 34103Republic of Korea Department of Mechanical System Design Engineering Seoul National University of Science and Technology232 Gongneung‑roNowon‑guSeoul 01811Republic of Korea Department of Mechanical Engineering(Department of Aeronautics Mechanical and Electronic Convergence Engineering)Kumoh National Institute of Technology61 Daehak‑roGumiGyeongbuk 39177Republic of Korea

Porous 2D materials with high conductivity and large surface area have been proposed for potential electromagnetic interference(EMI)shielding materials in future mobility and wearable applications to prevent signal noise,transmission inaccuracy,system malfunction,and health ***,we report on the synthesis of lightweight and flexible flash-induced porous graphene(FPG)with excellent EMI shielding *** broad spectrum of pulsed flashlight induces photo-chemical and photo-thermal reactions in polyimide films,forming 5×10 cm^(2)-size porous graphene with a hollow pillar structure in a few *** resulting material demonstrated low density(0.0354 g cm^(−3))and outstanding absolute EMI shielding effectiveness of 1.12×10^(5) dB cm^(2) g^(−1).The FPG was characterized via thorough material analyses,and its mechanical durability and flexibility were confirmed by a bending cycle ***,the FPG was utilized in drone and wearable applications,showing effective EMI shielding performance for internal/external EMI in a drone radar system and reducing the specific absorption rate in the human body.

关键词： Porous graphene Flash lamp Photo-pyrolysis High-throughput Electromagnetic interference shielding

E2E-BPF microscope:extended depth-of-field microscopy using learning-based implementation of binary phase filter and image deconvolution

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Light(Science & Applications) 2023年第12期12卷 2610-2623页

作者： Baekcheon Seong Woovin Kim Younghun Kim Kyung-A Hyun Hyo-il jung Jong-Seok lee Jeonghoon Yoo Chulmin Joo Department of Mechanical Engineering Yonsei UniversitySeoul 03722Republic of Korea The DABOM Inc Seoul 03722Republic of Korea School of Integrated Technology Yonsei UniversityIncheon 21983Republic of Korea

Several image-based biomedical diagnoses require high-resolution imaging capabilities at large spatial ***,conventional microscopes exhibit an inherent trade-off between depth-of-field(DoF)and spatial resolution,and thus require objects to be refocused at each lateral location,which is time ***,we present a computational imaging platform,termed E2E-BPF microscope,which enables large-area,high-resolution imaging of large-scale objects without serial *** method involves a physics-incorporated,deep-learned design of binary phase filter(BPF)and jointly optimized deconvolution neural network,which altogether produces high-resolution,high-contrast images over extended depth *** demonstrate the method through numerical simulations and experiments with fluorescently labeled beads,cells and tissue section,and present high-resolution imaging capability over a 15.5-fold larger DoF than the conventional *** method provides highly effective and scalable strategy for DoF-extended optical imaging system,and is expected to find numerous applications in rapid image-based diagnosis,optical vision,and metrology.

关键词： image diagnosis binary

Sex-dependent difference in the effect of metformin on colorectal cancer-specific mortality of diabetic colorectal cancer patients

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World Journal of Gastroenterology 2017年第28期23卷 5196-5205页

作者： jung Won Park Jin Ha lee Ye Hyun Park Soo jung Park Jae Hee Cheon Won Ho Kim Tae il Kim Department of Internal Medicine and Institute of Gastroenterology Yonsei University College of Medicine Cancer Prevention Center Yonsei University College of Medicine

To assess factors associated with the higher effect of metformin on mortality in diabetic colorectal cancer (CRC) patients, since the factors related to the effectiveness of metformin have not been identified *** January 2000 and December 2010, 413 patients diagnosed with both stage 3/4 CRC and diabetes mellitus were identified. Patients’ demographics and clinical characteristics were analyzed. The effect of metformin on CRC-specific mortality and the interactions between metformin and each adjusted factor were *** follow-up duration was median 50 mo (range: 1-218 mo). There were 85 deaths (45.9%) and 72 CRC-specific deaths (38.9%) among 185 patients who used metformin, compared to 130 total deaths (57.0%) and 107 CRC-specific deaths (46.9%) among 228 patients who did not use metformin. In multivariate analysis, survival benefit associated with metformin administration was identified (HR = 0.985, 95%CI: 0.974-0.997, P = 0.012). Interaction test between metformin and sex after adjustment for relevant factors revealed that female CRC patients taking metformin exhibited a significantly lower CRC-specific mortality rate than male CRC patients taking metformin (HR = 0.369, 95%CI: 0.155-0.881, P = 0.025). Furthermore, subgroup analysis revealed significant differences in CRC-specific mortality between the metformin and non-metformin groups in female patients (HR = 0.501, 95%CI: 0.286-0.879, P = 0.013) but not male patients (HR = 0.848, 95%CI: 0.594-1.211, P = 0.365). There were no significant interactions between metformin and other adjusted factors on CRC-specific *** showed a strong sex-dependent difference in the effect of metformin on CRC-specific mortality in advanced stage CRC patients with diabetes.

关键词： Colorectal cancer Metformin Survival Sex

Curative resection of leiomyosarcoma of the descending colon with metachronous liver metastasis: A case report

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World Journal of Gastrointestinal Surgery 2023年第5期15卷 992-999页

作者： Soo-Hyeon lee Sang-Ho Bae Sang-Cheol lee Tae-Sung Ahn Zisun Kim Hae-il jung Department of Surgery Soonchunhyang University Cheonan HospitalCheonan 31151ChungnamSouth Korea Department of Internal Medicine Soonchunhyang University Cheonan HospitalCheonan 31151ChungnamSouth Korea Department of Surgery Soonchunhyang University Bucheon HospitalBucheon 14584GyeonggiSouth Korea

BACKGROUND Leiomyosarcoma(LMS)has a poor prognosis and rarely originates from the *** resection is possible,surgery is the first treatment most commonly ***,no standard treatment exists for hepatic metastasis of LMS;although,several treatments,such as chemotherapy,radiotherapy,and surgery,have been ***,the management of liver metastases remains *** SUMMARY We present a rare case of metachronous liver metastasis in a patient with LMS originating from the descending colon.A 38-year-old man initially reported abdominal pain and diarrhea over the previous two *** revealed a 4-cm diameter mass in the descending colon,40 cm from the anal *** tomography revealed intussusception of the descending colon due to the 4-cm *** patient underwent a left *** analysis of the tumor revealed that it was positive for smooth muscle actin and desmin,and negative for cluster of differentiation 34(CD34),CD117,and discovered on gastrointestinal stromal tumor(GIST)-1,which are characteristic of gastrointestinal LMS.A single liver metastasis developed 11 mo postoperatively;the patient subsequently underwent curative resection *** patient remained disease-free after six cycles of adjuvant chemotherapy(doxorubicin and ifosfamide),and 40 and 52 mo after liver resection and primary surgery,*** cases were obtained from a search of Embase,PubMed,MEDLINE,and Google *** Early diagnosis and surgical resection may be the only potential curative options for liver metastasis of gastrointestinal LMS.

关键词： Leiomyosarcoma Colon Liver metastasis Surgical resection Treatment Case report

Determination of diffusion coefficient by image-based fluorescence recovery after photobleaching and single particle tracking system implemented in a single platform

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Journal of Innovative Optical Health Sciences 2021年第2期4卷 93-101页

作者： Donghee lee Jeonghoon lee jung Kyung Kim Department of Genetics Cell Biology and Anatomy University of Nebraska Medical CenterOmahaNE 68198USA School of Mechanical Engineering KOREA TECH Cheonan 31253Republic of Korea School of Mechanical Engineering and Department of Integrative Biomedical Science and Engineering Graduate School Kookmin University Seoul 02707Republic of Korea

Fluorescence recovery after photobleaching(FRAP)and single particle tracking(SPT)techni-ques determine the diffusion coefficient from average diffusive motion of high-concentration molecules and from trajectories of low-concentration single molecules,*** dif-fusion coefficients measured by FRAP and SPT techniques for the same biomolecule on cell membrane have exhibited inconsistent values across laboratories and platforms with larger dif-fusion coefficient determined by FRAP,but the sources of the inconsistency have not been investigated ***,we designed an image-based FRAP-SPT system and made a direct comparison between FRAP and SPT for diffusion coefficient of submicron particles with known theoretical values derived from Stokes-Einstein equation in aqueous *** combined iFRAP-SPT technique allowed us to measure the diffusion coefficient of the same fluorescent particle by utilizing both techniques in a single platform and to scrutinize inherent errors and artifacts of *** results reveal that diffusion coefficient overestimated by FRAP is caused by inaccurate estimation of the bleaching spot size and can be corrected by simple image *** iFRAP-SPT technique can be potentially used for not only cellular membrane dynamics but also for quantitative analysis of the spatiotemporal distribution of the solutes in small scale analytical devices.

关键词： Diffusion coefficient fluorescence recovery after photobleaching(FRAP) single particle tracking(SPT)

Stability for Leipholz’s Type of Laminated Box Columns with Nonsymmetric Lay-Ups on Elastic Foundation

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Advances in Applied Mathematics and Mechanics 2015年第2期7卷 158-179页

作者： Nam-il Kim Jaehong lee Department of Architectural Engineering Sejong University98 Kunja DongKwangjin KuSeoul 143-747Korea

The stability behavior of the Leipholz’s type of laminated box columns with nonsymmetric lay-ups resting on elastic foundation is investigated using theﬁnite el-ement *** on the kinematic assumptions consistent with the Vlasov beam theory,a formal engineering approach of the mechanics of the laminated box column-s with symmetric and nonsymmetric lay-ups is *** extended Hamilton’s principle is employed to obtain the elastic stiffness and mass matrices,the Rayleigh damping and elastic foundation matrices,the geometric stiffness matrix due to dis-tributed axial force,and the load correction stiffness matrix accounting for the uni-formly distributed nonconservative *** evaluation procedures for the critical values of divergence andﬂutter loads with/without internal and external damping ef-fects are brieﬂy *** examples are carried out to validate the present theory with respect to the previously published ***,the inﬂuences of theﬁber angle change and damping on the divergence andﬂutter loads of the laminated box columns are parametrically investigated.

关键词： Leipholz column laminate stability divergence ﬂutter ﬁnite element analysis

Neuroprotection by resveratrol-glucuronide and quercetin-glucuronide via binding to polyphenol-and glycosaminoglycan-binding sites in the laminin receptor

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Neural Regeneration Research 2025年第3期20卷 819-820页

作者： Rayudu Gopalakrishna Jennifer Aguilar Emily lee William J.Mack Department of Integrative Anatomical Sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Department of Neurological Surgery Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

The dietary polyphenolic compounds resveratrol and quercetin prevent neurodegenerative diseases in experimental models;however, they reach the brain only in nanomolar concentrations in the glucuronidated and sulfated ... 详细信息

关键词： resveratrol molar dated

Comparison of magnetic properties of DNA-cetyltrimethyl ammonium complex with those of natural DNA

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Science China Chemistry 2012年第5期55卷 814-821页

作者： KWON Young-Wan CHOI Dong Hoon JIN jung-il lee Chang Hoon KOH Eui Kwan GROTE James G. Department of Chemistry Korea University Seoul 136-701 Korea Department of Polymer Science & Engineering Chosun University Gwangju 501-759 Korea Korea Basic Science Institute-Seoul Branch Korea University Seoul 136-701 Korea US Air Force Research Laboratory Materials and Manufacturing Directorate AFRL/MLPS Wright-Patterson Air Force Base Ohio USA

We prepared the DNA-cetyltrimethyl ammonium complex, as well as the same complex intercalated with stable organic free radicals, and studied their magnetic properties by electron magnetic resonance (EMR) spectroscopy and by measuring the magnetization on a superconducting quantum interference device (SQUID). The UV-vis and CD spectra of DNA-quaternary alkyl ammonium complex (DNA--Q+) in organic solvent clearly demonstrated that it retained the double helical B-form conformation. The interhelical spacing of double strand DNA (dsDNA) increased when the counter ions (Na+) of phosphate groups of the natural DNA were replaced with the long alkyl quaternary ammonium groups. The inter-helical distance of DNA-cetyltrimethyl ammonium (CTMA) was 39.1  as confirmed by X-ray diffractometry. In general, the magnetization of the DNA-CTMA complex solid was found to be significantly lower than that of natural DNA. Moreover, intercalation of the complex with stable organic free radicals did not improve magnetization, which again was in marked contrast to natural DNA. EMR spectroscopic behavior of the complex in the solid state also was quite different from that of natural DNA: The unique broad EMR signal of natural DNA in the low field region with g-value greater than 10 disappeared in the DNA-CTMA complex.

关键词： natural DNA DNA-CTMA DNA-CTMA-PTMI magnetic property electron magnetic resonance (EMR) superconducting quantum interference device (SQUID)

Design and Implementation of 10 Gbps Optical Add-Drop Transponder

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光学学报 2003年第S1期23卷 657-658页

作者： Byoung-Sung Kim Seung-il Myong jung-Chan lee Je-Soo Ko Network Laboratory Electronics and Telecommunications Research Institute Daejeon Korea.Network Laboratory Electronics and Telecommunications Research Institute Daejeon Korea.Network Laboratory Electronics and Telecommunications Research Institute Daejeon Korea.Network Laboratory Electronics and Telecommunications Research Institute Daejeon Korea.

10 Gbps optical add-drop transponder, which can accommodate VSR (very short reach) to LR (long reach) subnetworks, is designed and implemented. The transponder consists of an OCA (optical transport network connection ... 详细信息

关键词： SONET VSR very LR FEC of Design and Implementation of 10 Gbps Optical Add-Drop Transponder SCA