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Application of artificial neural network to calculation of solitary wave run-up

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Water Science and Engineering 2010年第3期3卷 304-312页

作者： You-xing WEI Deng-ting WANG qing-jun liu College of Harbour Coastal and Offshore Engineering Hohai University Nanjing 210098 P. R. China River and Harbor Engineering Department Nanjing Hydraulic Research Institute Nanjing 210024 P. R. China

The prediction of solitary wave run-up has important practical significance in coastal and ocean engineering, but the calculation precision is limited in the existing models. For improving the calculation precision, a solitary wave run-up calculation model was established based on artificial neural networks in this study. A back-propagation （BP） network with one hidden layer was adopted and modified with the additional momentum method and the auto-adjusting learning factor. The model was applied to calculation of solitary wave run-up. The correlation coefficients between the neural network model results and the experimental values was 0.996 5. By comparison with the correlation coefficient of 0.963 5, between the Synolakis formula calculation results and the experimental values, it is concluded that the neural network model is an effective method for calculation and analysis of solitary wave ran-up.

关键词： solitary wave run-up artificial neural network back-propagation (BP) network,additional momentum method auto-adjusting learning factor

Synthesis and Unexpected Ring-opening Reaction of a New TADDOL Analogue with Chiral Cyclopropane Ring as Backbone

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Chinese Chemical Letters 2006年第5期17卷 606-608页

作者： jun liu qing Hua BIAN Ming An WANG Hong Chao GUO Min WANG Department of Applied Chemistry China Agricultural University Beijing 100094

Synthesis and ring-opening reaction of TADDOL analogue with cyclopropane as chiral backbone were described. A plausible ring-opening and carbonium ion rearrangement mechanism have been proposed.

关键词： TADDOL analogue ring-opening cyclopropane ring synthesis. tetraaryl-1 3-dioxolane-4 5-dimethanol

A New Approach of Data-driven Simulation and its Application to Solar Active Region 12673

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Research in Astronomy and Astrophysics 2024年第12期24卷 45-54页

作者： Zhi-Peng liu Chao-Wei Jiang Xin-Kai Bian qing-jun liu Peng Zou Xue-Shang Feng Institute of Space Science and Applied Technology Harbin Institute of Technology

The solar coronal magnetic field is a pivotal element in the study of eruptive phenomena, and understanding its dynamic evolution has long been a focal point in solar physics. Numerical models, driven directly by observation data, serve as indispensable tools in investigating the dynamics of the coronal magnetic field. This paper presents a new approach to electric field inversion, which involves modifying the electric field derived from the DAVE4VM velocity field using ideal Ohm's law. The time series of the modified electric field is used as a boundary condition to drive a magnetohydrodynamics model, which is applied to simulate the magnetic field evolution of active region12673. The simulation results demonstrate that our method enhances the magnetic energy injection through the bottom boundary, as compared with energy injection calculated directly from the DAVE4VM code, and reproduces the evolution of the photospheric magnetic flux. The coronal magnetic field structure is also in morphological similarity to the coronal loops. This new approach will be applied to the high-accuracy simulation of eruption phenomena and provide more details on the dynamical evolution of the coronal magnetic field.

关键词： magnetohydrodynamics (MHD) methods: numerical Sun: coronal mass ejections (CMEs) Sun: flares

Neurochip based on light-addressable potentiometric sensor with wavelet transform de-noising

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第5期11卷 323-331页

作者： qing-jun liu Wei-wei YE Hui YU Ning HU Li-ping DU Ping WANG Biosensor National Special Laboratory Key Laboratory of Biomedical Engineering of Ministry of Education Department of Biomedical Engineering Zhejiang University Hangzhou 310027 China State Key Laboratory of Transducer Technology Chinese Academy of Sciences Shanghai 200050 China

Neurochip based on light-addressable potentiometric sensor(LAPS),whose sensing elements are excitable cells,can monitor electrophysiological properties of cultured neuron networks with cellular signals well *** we report a kind of neurochip with rat pheochromocytoma(PC12) cells hybrid with LAPS and a method of de-noising signals based on wavelet *** were cultured on LAPS for several days to form networks,and we then used LAPS system to detect the extracellular potentials with signals de-noised according to decomposition in the time-frequency *** signal was decomposed into various scales,and coefficients were processed based on the properties of each *** last,signal was reconstructed based on the new *** results show that after de-noising,baseline drift is removed and signal-to-noise ratio is *** suggests that the neurochip of PC12 cells coupled to LAPS is stable and suitable for long-term and non-invasive measurement of cell electrophysiological properties with wavelet transform,taking advantage of its time-frequency localization analysis to reduce noise.

关键词： Neurochip Light-addressable potentiometric sensor(LAPS) Wavelet transform Threshold De-noising

Metabolic Regulation of Mammary Gland Epithelial Cells of Dairy Cow by Galactopoietic Compound Isolated from Vaccariae segetalis

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Agricultural Sciences in China 2011年第7期10卷 1106-1116页

作者： TONG Hui-li GAO Xue-jun LI qing-zhang liu Jie LI Nan WAN Zhong-ying Key Laboratory of Dairy Science Ministry of Education/Life College Northeast Agricultural University Harbin 150030 P.R.China

In previous experiment, we isolated a compound dibutyl phthalate （DBP） from Vaccaria segetalis which had galactopoietic function on mammary gland epithelial cells of dairy cow （DCMECs）. In this experiment, we ascertained the metabolic regulation function of DBP on DCMECs. Many genes related to lactation including Stat5, AMPK, b-casein, Glut1, SREBP-1, PEPCK, and ACC were detected by real-time PCR. Furthermore, Stat5 and AMPK were detected by Western blot and immunofluorescence co-localization, respectively. The results showed that DBP stimulates the expression of Stat5 and p-Stat5, thus activates Stat5 cell signal transduction pathway and stimulates b-casein synthesis. DBP also raises the activities of Glut1 and AMPK to stimulate glucose uptake and glycometabolism and activates the expression of AMPK downstream target genes PEPCK and ACC and expression of SREBP-1 to stimulate milk fat synthesis. In addition, the activities of HK, G-6-PDH, ICDH, ATPase, and energy charges were stimulated by DBP to increase the energy metabolism level of DCMECs. The results showed DBP stimulates energy metabolism related to galactopoietic function in DCMECs.

关键词： Vaccaria segetalis DBP dairy cow mammary gland epithelial cell metabolic regulation

The application of EBSP in the research of deformation microstructure of metals

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电子显微学报 2001年第4期20卷 348-349页

作者： WU qing lan,WU Gui lin,MENG jun,liu qing,liu Wei (Department of materials science and technology, Tsinghua University,Beijing 100084) 清华大学北京 100084

The basic principle and application of EBSP in the research of deformed microstructure are illustrated in this paper. The results suggest that EBSP can be applied in the research of deformation microstructure and crys... 详细信息

关键词： EBSP deformation microstructure crystallography

Predicting liver metastasis of gastrointestinal tract cancer by diffusion-weighted imaging of apparent diffusion coefficient values

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World Journal of Gastroenterology 2016年第10期22卷 3031-3037页

作者： De-Xian Zheng Shu-Chun Meng qing-jun liu Chuan-Ting Li Xi-Dan Shang Yu-Seng Zhu Tian-jun Bai Shi-Ming Xu Department of Radiology Second People’s Hospital of Liaocheng City Department of Radiology Third People’s Hospital of Liaocheng city Medical Imaging Institute of Shandong Province Shandong Provincial Hospital Department of Gastroenterology Second People’s Hospital of Liaocheng city Department of Radiology People’s Hospital of Liaocheng city

AIM: To determine if efficacy of chemotherapy on liver metastasis of gastrointestinal tract cancer can be predicted by apparent diffusion coefficient(ADC) values of diffusion-weighted imaging(DWI). METHODS: In total, 86 patients with liver metastasis of gastrointestinal tract cancer(156 metastatic lesions) diagnosed in our hospital were included in this study. The maximum diameters of these tumors were compared with each other before treatment, 2 wk after treatment, and 12 wk after treatment. Selected patients were classified as the effective group and the ineffective group, depending on the maximum diameter of the tumor after 12 wk of treatment; and the ADC values at different treatment times between the two groups were compared. Spearman rank correlation was used to analyze the relationship between ADC value and tumor diameter. Receiver operating characteristic curve(ROC curve) was used to analyze the ADC values before treatment to predict the patient's sensitivity and specificity degree of efficacy to the chemotherapy. RESULTS: There was no difference in age between the two groups and in maximum tumor diameter before treatment and 2 wk after treatment. However, after 12 wk of treatment, maximum tumor diameter in the effective group was significantly lower than that in the ineffective group(P < 0.05). Before treatment, ADC values in the ineffective group were significantly higher than those in the effective group(P < 0.05). There was no difference in ADC values between the effective and ineffective groups after 2 and 12 wk of treatment. However, ADC values were significantly higher after 2 and 12 wk of treatment compared to before treatment in the effective group(P < 0.05). Spearman rank correlation analysis showed that ADC value before treatment and the reduced percentage of the maximum tumor diameter after 12 wk of treatment were negatively correlated, while the increase in the percentage of the ADC value 12 wk after treatment and the decrease in the percentage

关键词： Chemotherapy Liver metastatic tumor Magnetic resonance imaging Gastrointestinal tract cancer

Surgical Treatment of Ankle Syndesmosis Injuries with Syndesmosis Elastic Hook

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Chinese Medical Journal 2016年第22期129卷 2749-2752页

作者： Jian-Yun Miao qing-jun liu Bin Lin Lin-Xin Guo Orthopaedic Center of PLA The 175^th Hospital of PLA Affiliated Southeast Hospital of Xiamen University Zhangzhou Fujian 363000 China

INTRODUCTIONDistal tibiofibular syndesmosis injuries are usually associated with ankle fractures, especially common in Denis B and C fractures. Syndesmosis is essential for stability of the ankle mortise that is required for weight transmission and walking. The syndesmosis consists of the anteroinferior tibiofibular ligament, posteroinferior tibiofibular ligament, inferior transverse tibiofibular ligament, and interosseous membrane. Internal fixations of the syndesmosis were recommended by most authors to repair the associated ruptured ligaments, which bring about the adverse consequences of limiting the physiological micromovement of the tibiofibular joint to some extent.

关键词： Distal Tibiofibular Syndesmosis Elastic Hook Syndesmosis Injuries

CATALYTIC SYNTHESIS OF α-CYANO-α,β-UNSATURATED SULPHONES IN THE PRESENCE OF ORGANOTELLURIUM OXIDE

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Chinese Chemical Letters 1991年第9期2卷 683-684页

作者： Qi ZHONG Yong jun LU Chang qing liu Wei Guo TAO Yong jun ZOU Chemistry Department,Yangzhou Teachers College,Yangzhou,225002

Using bis(p-methoxyphenyl)telluroxide(BMPTO)as the catalyst, phenylsulphonyl acetonitrile condensed easily with aromatic aldehydes at room temperature to give -cyano- ,β-unsaturated sulphones in high yields.

关键词： OC UNSATURATED SULPHONES IN THE PRESENCE OF ORGANOTELLURIUM OXIDE CATALYTIC SYNTHESIS OF CYANO De