检索结果-南通市图书馆

Automatic detection of small bowel lesions with different bleeding risks based on deep learning models

World Journal of Gastroenterology 2024年第2期30卷 170-183页

作者： Rui-Ya Zhang Peng-Peng Qiang Ling-jun Cai Tao Li Yan Qin Yu Zhang Yi-Qing Zhao jun-ping wang Department of Gastroenterology The Fifth Clinical Medical College of Shanxi Medical UniversityTaiyuan 030012Shanxi ProvinceChina School of Computer and Information Technology Shanxi UniversityTaiyuan 030006Shanxi ProvinceChina School of Life Sciences and Technology Mudanjiang Normal UniversityMudanjiang 157011Heilongjiang ProvinceChina

BACKGROUND Deep learning provides an efficient automatic image recognition method for small bowel(SB)capsule endoscopy(CE)that can assist physicians in ***,the existing deep learning models present some unresolved *** To propose a novel and effective classification and detection model to automatically identify various SB lesions and their bleeding risks,and label the lesions accurately so as to enhance the diagnostic efficiency of physicians and the ability to identify high-risk bleeding *** The proposed model represents a two-stage method that combined image classification with object ***,we utilized the improved ResNet-50 classification model to classify endoscopic images into SB lesion images,normal SB mucosa images,and invalid ***,the improved YOLO-V5 detection model was utilized to detect the type of lesion and its risk of bleeding,and the location of the lesion was *** constructed training and testing sets and compared model-assisted reading with physician *** The accuracy of the model constructed in this study reached 98.96%,which was higher than the accuracy of other systems using only a single *** sensitivity,specificity,and accuracy of the model-assisted reading detection of all images were 99.17%,99.92%,and 99.86%,which were significantly higher than those of the endoscopists’*** image processing time of the model was 48 ms/image,and the image processing time of the physicians was 0.40±0.24 s/image(P<0.001).CONCLUSION The deep learning model of image classification combined with object detection exhibits a satisfactory diagnostic effect on a variety of SB lesions and their bleeding risks in CE images,which enhances the diagnostic efficiency of physicians and improves the ability of physicians to identify high-risk bleeding groups.

关键词： Artificial intelligence Deep learning Capsule endoscopy Image classification Object detection Bleeding risk

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stress Responsive Zinc-finger Protein Gene of Populus euphratica in Tobacco Enhances Salt Tolerance

引用

Journal of Integrative Plant Biology 2008年第1期50卷 56-61页

作者： jun-Ying wang Xin-Li Xia jun-ping wang Wei-Lun Yin Biotechnology Research Institute of Chinese Academy of Agncultural Sciences Beijing 100081 China Beijing Forestry University Beijing 100083 China Tianjin University of Science and Technology Tianjin 300222 China

The Populus euphratica stress responsive zinc-finger protein gene PSTZ, which encodes a protein including typical Cys2/His2 zinc finger structure, was isolated by reverse transcription-polymerase chain reaction from P. euphratica. Northern hybridization revealed that its expression was induced under drought and salt stress conditions. To examine its function, cDNA of the PSTZ gene, driven by the cauliflower mosaic virus 35S promoter, was cloned into a plant expression vector pBin438 and introduced into tobacco plants. Transgenic tobacco showed an enhanced salt tolerance, suggesting that PSTZ may play a role in plant responsiveness to salt stress.

关键词： enhance Populus euphratica, salt tolerance stress responsive zinc-finger protein.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of Al component content on optoelectronic properties of Al_xGa_(1-x)N

引用

Chinese Physics B 2018年第10期27卷 495-500页

作者： Yan-jun Ji jun-ping wang You-Wen Liu College of Science Nanjing University of Aeronautics and AstronauticsNanjing 211106China College of Aeronautical Engineering Bingzhou UniversityBingzhou 256603China

Using density functional theory, the electronic structures, lattice constants, formation energies, and optical properties of AlxGa1-xN are determined with Al component content x in a range from 0 to 1. As x increases, the lattice constants decrease in e-exponential form, and the band gap increases with a band bending parameter b=0.3954. The N–Al interaction force in the（0001） direction is greater than the N–Ga interaction force, while the N–Al interaction force is less than the N–Ga interaction force in the（10ī0） direction. The formation energies under different Al component content are negative and increase with Al component content increasing. The static dielectric function decreases, the absorption edge has a blue shift, and the energy loss spectrum moves to high energy with the Al component content increasing.

关键词： GaN photocathode electronic structure optical properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Efficacy of β-adrenergic blocker plus 5-isosorbide mononitrate and endoscopic band ligation for prophylaxis of esophageal variceal rebleeding:A meta-analysis

引用

World Journal of Gastroenterology 2009年第17期15卷 2151-2155页

作者： Shi-Hua Ding jun Liu Jian-ping wang Department of Gastroenterology The Affiliated Shenzhen Hospital Nanfang Medical University Shenzhen 518035 Guangdong Province China

AIM: To systematically assess the efficacy and safety of β-adrenergic blocker plus 5-isosorbide mononitrate (BB + ISMN) and endoscopic band ligation (EBL) on prophylaxis of esophageal variceal rebleeding. METHODS: Randomized controlled trials (RCTs) comparing the efficacy and safety of BB + ISMN and EBL on prophylaxis of esophageal variceal rebleeding were gathered from Medline, Embase, Cochrane Controlled Trial Registry and China Biological Medicine database between January 1980 and August 2007. Data from five trials were extracted and pooled. The analyses of the available data using the Revman 4.2 software were based on the intention-to-treat principle. RESULTS: Four RCTs met the inclusion criteria. In comparison with BB + ISMN with EBL in prophylaxis of esophageal variceal rebleeding, there was no significant difference in the rate of rebleeding [relative risk (RR), 0.79; 95% CI: 0.62-1.00; P = 0.05], bleeding-related mortality (RR, 0.76; 95% CI: 0.31-1.42; P = 0.40), overall mortality (RR, 0.81; 95% CI: 0.61-1.08; P = 0.15) and complications (RR, 1.26; 95% CI: 0.93-1.70; P = 0.13). CONCLUSION:In the prevention of esophageal variceal rebleeding, BB + ISMN are as effective as EBL. There are few complications with the two treatment modalities. Both BB + ISMN and EBL would be considered as the first-line therapy in the prevention of esophageal variceal rebleeding.

关键词： Meta-analysis Esophageal variceal rebleeding Endoscopic band ligation β-adrenergicblocker 5-isosorbide mononitrate Prophylaxis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ubiquitin-conjugating enzyme E2T knockdown suppresses hepatocellular tumorigenesis via inducing cell cycle arrest and apoptosis

引用

World Journal of Gastroenterology 2019年第43期25卷 6386-6403页

作者： Jian Guo Mu wang jun-ping wang Chang-Xin Wu Institute of Biotechnology Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of EducationInstitute of BiotechnologyShanxi UniversityTaiyuan 030006Shanxi ProvinceChina Department of General Surgery Shanxi Provincial People’s Hospitalthe Affiliated People’s Hospital of Shanxi Medical UniversityTaiyuan 030012Shanxi ProvinceChina Department of Neurology Shanxi Provincial People’s Hospitalthe Affiliated People’s Hospital of Shanxi Medical UniversityTaiyuan 030012Shanxi ProvinceChina Department of Gastroenterology Shanxi Provincial People’s Hospitalthe Affiliated People’s Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina The Institutes of Biomedical Sciences Shanxi UniversityTaiyuan 03006Shanxi ProvinceChina Key Laboratory of Molecular Biology and Biochemistry of Ministry of Education Shanxi UniversityTaiyuan 030006Shanxi ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)is now the most common primary liver malignancy worldwide,and multiple risk factors attribute to the occurrence and development of ***,increasing studies suggest that ubiquitinconjugating enzyme E2T(UBE2T)serves as a promising prognostic factor in human cancers,although the molecular mechanism of UBE2T in HCC remains *** To investigate the clinical relevance and role of UBE2T in HCC *** UBE2T expression in HCC tissues from the TCGA database and its association with patient survival were analyzed.A lentivirus-mediated strategy was used to knock down UBE2T in HCC ***-PCR and Western blot assays were performed to check the effect of UBE2T silencing in HCC *** growth in vitro and in vivo was analyzed by multiparametric high-content screening and the xenograft tumorigenicity assay,*** cycle distribution and apoptosis were determined by flow *** genes regulated by UBE2T were profiled by microarray *** UBE2T was overexpressed in HCC tissues compared with paired and non-paired normal *** expression of UBE2T predicted a poor overall survival in HCC *** vitro,lentivirus-mediated UBE2T knockdown significantly reduced the viability of both SMMC-7721 and BEL-7404 *** vivo,the xenograft tumorigenesis of SMMC-7721 cells was largely attenuated by UBE2T *** cell cycle was arrested at G1/S phase in SMMC-7721 and BEL-7404 cells with UBE2T ***,apoptosis was increased by UBE2T *** the molecular level,numerous genes were dysregulated after UBE2T silencing,including IL-1B,FOSL1,PTGS2,and *** UBE2T plays an important role in cell cycle progression,apoptosis,and HCC development.

关键词： Hepatocellular carcinoma Ubiquitin-conjugating enzyme E2T Cell cycle Apoptosis Tumorigenesis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Short-term efficacy and influencing factors of conventional chemotherapy combined with irinotecan in patients with advanced gastric cancer

引用

World Journal of Gastrointestinal Oncology 2023年第1期15卷 143-154页

作者： jun-ping wang Jian-Lei Du Ya-Ying Li Pharmacy Department Zhumadian Central HospitalZhumadian 463000Henan ProvinceChina

BACKGROUND Gastric cancer is one of the most common cancers worldwide, with a 5-year survival rate of only 20%. The age of onset of gastric cancer is in line with the general rule of cancer. Most of them occur after middle age, mostly between 40and 60 years old, with an average age of about 50 years old, and only 5% of patients are under 30 years old. The incidence of male is higher than that of *** To investigate the short-term efficacy and influencing factors of chemotherapy combined with irinotecan in patients with advanced gastric *** Eighty patients with advanced gastric cancer who were treated in our hospital from January 2019 to January 2022 were selected. The patients were divided into an observation group(n = 40) and control group(n = 40) by the envelope *** control group was given preoperative routine chemotherapy. The observation group was treated with irinotecan in addition to the chemotherapy given to the control group. The short-term efficacy of treatment in the two groups, as well as tumor marker levels and quality of life before and after treatment were *** The short-term treatment effect in the observation group was better than that in the control group(P < 0.05), and the total effective rate was 57.50%. The age and proportion of tumor node metastasis(TNM) stage IV patients with ineffective chemotherapy in the observation group were(65.12 ± 5.71) years and 52.94%,respectively, which were notably higher than those of patients with effective chemotherapy(P < 0.05), while the Karnofsky Performance Scale score was(67.70± 3.83) points, which was apparently lower than that of patients with effective chemotherapy(P <0.05). After 3 mo of treatment, the SF-36 scale scores of physiological function, energy, emotional function, and mental health in the observation group were 65.12 ± 8.14, 54.76 ± 6.70, 47.58 ± 7.22,and 66.16 ± 8.11 points, respectively, which were considerably higher than those in the control group(P < 0.

关键词： Advanced gastric cancer Conventional chemotherapy Irinotecan Efficacy Quality of life

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sterically Stabilized Poly(3, 4-ethylenedioxythiophene) Colloidal Dispersions Doped with Different Sulfonic Acids

引用

Chinese Chemical Letters 2006年第10期17卷 1391-1393页

作者： Tie jun wang ping CHEN Xiu Jie HU Shu Yun ZHOU Technical Institute of Physics and Chemistry Chinese Academy of Science Beijing 100080

The preparation of sterically stabilized poly（3, 4-ethylenedioxythiophene）（PEDOT） colloidal dispersions doped with different sulfonic acids is described. Three different sulfonic acids, i.e., p-toluenesulfonic acid, β-naphthalenesulfonic acid and D-camphor-10-sulfonic acid are used, facilitating the preparation of sterically stable PEDOT colloidal particles. The influences of the dopants and concentration of polymeric stabilizer on the yields, morphologies and electrical properties of the resultant colloidal particles were investigated. The colloidal particles with the size ranging from 172 to 334 nm have been obtained in good yields. The compressed pellet conductivity was as high as 4.5 Scm^-1

关键词： PEDOT sulfonic acid colloidal particles polymeric stabilizer conductivity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

MiR-32-5p aggravates intestinal epithelial cell injury in pediatric enteritis induced by Helicobacter pylori

引用

World Journal of Gastroenterology 2019年第41期25卷 6222-6237页

作者： Jing Feng Jian Guo jun-ping wang Bao-Feng Chai Institute of Loess Plateau Shanxi UniversityTaiyuan 030006Shanxi ProvinceChina Department of Gastroenterology Shanxi Provincial People's HospitalThe Affiliated People's Hospital of Shanxi Medical UniversityTaiyuan 030012Shanxi ProvinceChina Department of General Surgery Shanxi Provincial People's HospitalThe Affiliated People's Hospital of Shanxi Medical UniversityTaiyuan 030012Shanxi ProvinceChina

BACKGROUND Pediatric enteritis is one of the infectious diseases in the digestive system that causes a variety of digestive problems,including diarrhea,vomiting,and bellyache in ***,Helicobacter pylori(***)infection is one of the common factors to cause pediatric *** has been demonstrated that aberrant expression of microRNAs(miRNAs)is found in gastrointestinal diseases caused by ***,and we discovered a significant increase of miR-32-5p in ***-related pediatric ***,the exact role of miR-32-5p in it is still *** To investigate the role of aberrant miR-32-5p in pediatric enteritis induced by *** MiR-32-5p expression was detected by quantitative real time-polymerase chain *** biological role of miR-32-5p in ***-treated intestinal epithelial cells was evaluated by Cell Counting Kit-8 assay and flow *** potential target of miR-32-5p was predicted with TargetScanHuman and verified by luciferase *** downstream mechanism of miR-32-5p was explored by using molecular biology *** We found that miR-32-5p was overexpressed in serum of ***-induced pediatric *** investigation revealed that *** infection promoted the death of intestinal epithelial cells,and increased miR-32-5p ***,miR-32-5p mimic further facilitated apoptosis and inflammatory cytokine secretion of intestinal epithelial *** exploration revealed that SMAD family member 6(SMAD6)was the direct target of miR-32-5p,and SMAD6 overexpression partially rescued cell damage induced by *** following experiments showed that miR-32-5p/SMAD6 participated in the apoptosis of intestinal epithelial cells induced by transforming growth factor-β-activated kinase 1(TAK1)-p38 activation under *** *** Our work uncovered the crucial role of aberrant expression of miR-32-5p in ***–related pediatric enteritis,and suggested that the TAK1-p38

关键词： MiR-32-5p SMAD family member 6 Transforming growth factor-β-activated kinase 1 Apoptosis Enteritis Helicobacter pylori

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Faecal and mucosal microbiota in patients with functional gastrointestinal disorders: Correlation with toll-like receptor 2/toll-like receptor 4 expression

引用

World Journal of Gastroenterology 2017年第36期23卷 6665-6673页

作者： Li-Na Dong jun-ping wang ping Liu Yun-Feng Yang Jing Feng Yi Han Central Laboratory Shanxi Provincial People's HospitalShanxi Medical University Department of Gastroenterology Shanxi Provincial People's HospitalShanxi Medical University Department of Gynaecology Shanxi Provincial People's HospitalShanxi Medical University

AIM To investigate the intestinal luminal microbiota(LM)and mucosa-associated microbiota(MAM)in Chinese patients with functional gastrointestinal disorders(FGIDs)and examine the association between these communities and the expression of toll-like receptor(TLR)2 and TLR4. METHODS Thirty-two Chinese subjects who suffered from symptoms of FGIDs,as confirmed by gastroenterologists,were enrolled in this *** faecal samples and descending colonic mucosal biopsies were collected from the subjects before(faecal)and during(mucosal) flexible *** analysis of the samples,we performed high-throughput sequencing of the V3-V4region of the 16S rR NA gene and reverse transcription(RT)-PCR to detect the expression of colonic TLR2 and *** in the stool and mucosal microbiota were examined and a correlation network analysis was performed. RESULTS The microbiota of faecal samples was significantly more diverse and richer than that of the mucosal samples,and the LM and MAM populations differed ***2 expression showed a significant positive correlation with TLR4 *** the MAM samples,the genera Faecalibacterium and Ruminococcus,which belong to the family Ruminococcaceae,were inversely correlated with TLR4 expression(r=-0.45817,P=0.0083 and r=-0.5306,P=0.0018,respectively).Granulicatella,which belongs to Carnobacteriaceae,and Streptococcus,which belongs to Streptococcaceae,were inversely correlated with TLR2 expression(r=-0.5573,P=0.0010 and r=-0.5435,P=0.0013,respectively).In the LM samples,examination at phylum,class,or order level revealed no correlation with TLR4 ***,which belongs to Ruminococcaceae,and Streptococcus,which belongs to Streptococcaceae,were inversely correlated with TLR2 expression(r=-0.5743,P=0.0058 and r=-0.3905,P=0.0271,respectively). CONCLUSION Microbial compositions of LM and MAM in Chinese patients with FGIDs are *** of TLRs may be affected by the type of bacteria that are

关键词： Gastrointestinal microbiota 16S rRNA gene Toll-like receptors High-throughput sequencing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of preparation methods on Pt/alumina catalysts for the hydrogen iodide catalytic decomposition

引用

Chinese Chemical Letters 2009年第1期20卷 102-105页

作者： Zhi Chao wang Lai jun wang ping Zhang Song Zhe Chen Jing Ming Xu Jing Chen Laboratory 201 Institute of Nuclear and New Energy Technology Tsinghua University Beijing 102201 China

Three kinds of Pt/alumina catalysts were prepared by impregnation-hydrogen reduction, impregnation-hydrazine reduction and electroless plating methods. Their differences in the structures, specific areas and particle sizes were characterized by XRD, BET and TEM, respectively. Furthermore, their catalytic activities for the hydrogen iodide （HI） decomposition were evaluated in a fixed bed reactor. The results show that the catalyst 5%Pt/Al2O3 prepared by the electroless plating has the optimum catalytic properties for HI decomposition owing to the high dispersion of the platinum nano-particles （〈5 nm） on the alumina supports.

关键词： Hydrogen iodide Catalytic decomposition Pt/At2O3 Preparation methods

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：