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Optical Waveguide Formation in LiNbo_(3) by the 2.6 MeV Nickel Ions Implantation

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Chinese Physics Letters 2001年第2期18卷 242-244页

作者： HU Hui CHEN Feng lu Fei ZHANG Jian-Hua LIU Ji-Tian WANG Ke-Ming SHI bo-Rong SHEN Ding-Yu WANG Xue-Mei Department of Physics Shandong UniversityJi’nan 250100 Department of Physics University of OsnabrueckD-49069OsnabrueckGermany MOE Key Laboratory of Heavy Ion Physics Peking UniversityBeijing 100871

The optical waveguide was formed on an LiNbo_(3) substrate by 2.6 MeV nickel ions implantation to the dose of 9×10^(14) ions/cm^(2).Five dark modes were observed by the prism coupling *** refractive index profile was obtained by using the reflectivity calculation method.A large index decrease was found in the guiding region and in the optical barrier,which is somewhat different from that of the LiNbo_(3) waveguide formed by the MeV He+*** position of the optical barrier is deeper than that of the damage peak calculated by TRIM'90(Transport of Ions in Matter)*** crystal lattice damage in the guiding region caused by the Ni+ion implantation was analysed by the Rutherford backscattering/channelling technique.

关键词： technique waveguide implantation

Detection of metastatic cancer cells in mesentery of colorectal cancer patients

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World Journal of Gastroenterology 2017年第34期23卷 6315-6320页

作者： Xue-Lai luo Da-Xing Xie Jian-Xin Wu An-Ding Wu Zong-Qing Ge Hai-Jie Li jun-bo Hu Zhi-Xin Cao Jian-Ping Gong Tongji Cancer Research Institute Department of Gastrointestinal SurgeryTongji HospitalTongji Medical College of Huazhong University of Science and Technology

AIM To detect the existence of isolated cancer cells in the mesentery of colorectum(named as Metastasis V), and investigate its clinical significance in colorectal cancer(CRC) *** Sixty-three CRC patients who received radical excision between January 2012 and September 2015 were included. All the patients underwent laparoscopyassisted radical colorectomy or proctectomy [with complete mesocolic excision(CME) or total mesorectal excision(TME)] with R0 dissections at the Department of Gastrointestinal Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology. The location and size of the primary lesions were recorded immediately after the tumor was removed, with the surrounding mesenterium completely separated along the intestinal wall. Each dissected mesentery sample was analyzed for hematoxylin-eosin staining and immunohistochemistry using cytokeratin 19 antibody. Image Pro Plus Software 6.0(Media Cybernetics, CA, United States) was usedto semi-quantitatively measure the concentration of the cytokeratin 19 immunohistochemistry. The correlation between metastasis found in mesentery and clinicopathological characteristics was examined. The prognosis of patients was also evaluated by preoperative serum CEA *** Metastasis V was detected in 14 of 63(22.2%) CRC patients who underwent laparoscopy-assisted radical colorectomy or proctectomy(with CME or TME) with R0 dissection in our hospital between January 2012 and September 2015. There was no significant difference in age, gender, tumor size, and tumor location in patients with Metastasis V(P > 0.05). Metastasis V was more likely to occur in poorly differentiated tumor(5/11; 45.5%) than moderately(8/46; 17.4%) and welldifferentiated one(1/6; 16.7%). The Metastasis V in N2 stage(9/14; 64.3%) was more frequent that in the N0 stage(3/35; 8.6%) or N1 stages(2/14; 14.3%). In addition, Metastasis V was positively related to the tumor invasive depth(T1:0/1, 0%; T2:1/12,

关键词： Colorectal cancer Colorectal mesentery Serum CEA level Radical surgery Metastasis V

Quantitative and qualitative assessment of non-obstructive left main coronary artery plaques using 64-multislice computed tomography compared with intravascular ultrasound

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Chinese Medical Journal 2010年第7期123卷 827-833页

作者： SHEN Yi QIAN Ju-ying WANG Ming-hui LIU Yuan LIU Xue-bo GE Lei MA Jian-ying GE jun-bo Department of Internal Medicine Zhongshan Hospital Fudan University Shanghai Institute of Cardiovascular Diseases Shanghai 200032 China Department of Cardiology Zhongshan Hospital Fudan University Shanghai Institute of Cardiovascular Diseases Shanghai 200032 China Department of Cardiology Zhongshan Hospital Fudan University Shanghai Institute of Cardiovascular Diseases Shanghai 200032 China

Background There are few reports of quantitative and qualitative measuring of left main coronary artery （LMCA） plaques by multislice computed tomography coronary angiography （MSCTA）, especially when compared with intravascular ultrasound （IVUS） as reference standard. The aim of this study was to evaluate the use of 64-MSCTA in the diagnosis of LMCA disease, and the accuracy of MSCTA in the quantitative and qualitative assessment of the LMCA lesion as compared with *** A total of 91 patients （53 men, 38 women, mean age （64.78±9.19） years） were examined by 64-MSCTA and IVUS. Compared with the IVUS, the sensitivity, specificity, positive and negative predictive values （PPV and NPV） of the MSCTA on the diagnosis of LMCA diseases were calculated. Also, kappa index （K） for the agreement between MSCTA and IVUS was calculated. Minimal lumen area （MLA）, external elastic membrane cross-sectional area （EEM-CSA） and plaque burden were measured by two blinded and independent operators on MSCTA cross-sectional reconstruction and compared with the parameters measured from IVUS by manually tracing. The CT value of soft, fibrous and calcific plaques was measured using IVUS classification of the *** The sensitivity, specificity, PPV and NPV of MSCTA for detecting LMCA plaques were 93.1%, 84.2%, 95.7%, 76.2%, respectively. Kappa index （K=0.744, P〈0.001） indicated excellent agreement between MSCTA and IVUS. The Pearson index between MLA on IVUS and MLA on MSCTA was 0.815 （P 〈0.01）. The Pearson index of plaque burden and EEM-CSA between IVUS and MSCTA was 0.736 and 0.740 respectively （both P 〈0.01）. The CT value of soft plaque, fibrous plaque and calcific plaque compared with IVUS were （52.52±15.71） HU, （108.32±43.44） HU and （604.16±377.67） HU （P〈0.001）. Receiver operating characteristic curve analysis of CT value of non-calcific plaques for predicting soft plaques showed the cutpoint was 54.35 HU, with a sensitivity of 83.3% and specificity of 94.4%. Conclusions Si

关键词： multislice computed tomography intravascular ultrasound left main coronary artery

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捷联惯导摇摆基座自对准中圆锥误差补偿算法

兵工学报 2012年第7期33卷 826-830页

作者：王立冬刘军鲁军军械工程学院河北石家庄050003

针对捷联惯导系统(SINS)在摇摆基座上的自对准误差,提出了减小圆锥误差、提高自对准精度的具体圆锥误差补偿算法。分析比较了四元数四阶龙格-库塔算法、等效转动矢量的二子样、三子样等圆锥误差补偿算法及其理论补偿效果。结合仿真和实... 详细信息

针对捷联惯导系统(SINS)在摇摆基座上的自对准误差,提出了减小圆锥误差、提高自对准精度的具体圆锥误差补偿算法。分析比较了四元数四阶龙格-库塔算法、等效转动矢量的二子样、三子样等圆锥误差补偿算法及其理论补偿效果。结合仿真和实验结果得出:自对准误差随算法子样数的增大而降低,子样数增加1,北向对准误差减小近1倍,姿态角的离散度降低;随摇摆幅度的增大和频率的提高,三子样补偿算法的自对准精度接近稳定;综合考虑采样频率、子样数、计算量和对准精度要求,选择三子样圆锥误差补偿算法可以满足SINS摇摆基座下的自对准要求。

关键词：飞行器控制、导航技术捷联惯导系统自对准误差圆锥误差子样数

A rhizobia strain isolated from root nodule of gymno-sperm Podocarpus macrophyllus

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Science China(Life Sciences) 2007年第2期50卷 228-233页

作者： HUANG BaoLing, lu ChengQun, WU bo & FAN LiQin 1 Forestry College, Guangxi University, Nanning 530004, China 2 Guangxi Key Laboratory of Subtropical Bioresource Conservation and Utilization, Nanning 530004, China 1. Forestry College Guangxi University Nanning 530004 China 2. Guangxi Key Laboratory of Subtropical Bioresource Conservation and Utilization Nanning 530004 China

Symbiotic nitrogen fixation of rhizobia and leguminous plants is considered as the most important biologic nitrogen fixation system on earth. Symbiotic nodulation of gymnosperm Podocarpus macro-phyllus and rhizobia has never been reported. In this study, 11 endophytic bacteria strains were isolated from root nodules of P. macrophyllus and its variation P. macrophyllus var. maki. The plant infection tests on these strains indicated that the isolated strains could be nodulated on P. macrophyllus plants, and weak nitrogenase activity of nodules was found in acetylene reduction method. According to the physiological and biochemical characteristics of the 11 strains, GXLO 02 was selected as the representative strain. 16S rDNA full-length sequence analysis of GXLO 02 confirmed that the representative strain GXLO 02 belongs to Rhizobium sp.

关键词： Podocarpus macrophyllus P. macrophyllus var. maki rhizobia physiological and biochemical characteristics 16S rDNA sequence

Multi-objective Optimization of Methyl Acetate Hydrolysis Process Based on NSGA-Ⅱ Algorithm

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Multi-objective Optimization of Methyl Acetate Hydrolysis Pr...

第30届中国控制与决策会议

作者： YIN junHua bo CuiMei LI jun HUANG Yan College of Electrical Engineering and Control Science Nanjing University of Technology

An enhanced non-dominated sorting genetic algorithm（NSGA-II） was applied to carry out the integer optimized design in this *** steady simulation design was established based on the reaction kinetics analysis using Aspen Plus,and the feasible region of each optimized variable was calculated through sensitive *** at the total cost TAC as the objective function,the NSGA-II algorithm was used directly to obtain the Pareto optimal solutions under the constraints of feasible region of *** simulation results showed that the NSGA-II algorithm can effectively reduce the total cost of TAC.

关键词： Hydrolysis of methyl acetate Steady-state simulation Economic optimization NSGA-Ⅱ optimization

来源： cnki会议评论

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应用三分量地震数据反演煤系地层孔隙含水量

地球物理学报 2010年第7期53卷 1734-1740页

作者：芦俊王赟赵伟中国地质大学(北京)能源学院北京100083 中国科学院地球化学研究所贵阳550002 煤矿瓦斯治理国家工程研究中心安徽淮南232052

地层孔隙水含量的计算主要受地层孔隙度与孔隙含水饱和度的影响.通过实验室煤层及其顶底板岩芯物理测试与孔隙度测量,可以获得煤系地层岩芯的孔隙度与岩芯纵、横波速度的经验公式;结合三分量地震勘探获得的纵波与横波速度,能够计算出煤... 详细信息

地层孔隙水含量的计算主要受地层孔隙度与孔隙含水饱和度的影响.通过实验室煤层及其顶底板岩芯物理测试与孔隙度测量,可以获得煤系地层岩芯的孔隙度与岩芯纵、横波速度的经验公式;结合三分量地震勘探获得的纵波与横波速度,能够计算出煤系地层的孔隙度;含水饱和度的计算通过实验室岩电参数测试和阿尔奇公式可以计算得到.结合淮南某矿区三维三分量地震勘探和地球物理测井及岩样的岩电试验,实现了三维空间煤系地层孔隙含水体积百分比的精确计算.该预测方法与传统的、钻孔控制的地下水评价方法相比可以提供相对精细的、三维空间的、定量化的煤系地层孔隙相对含水量,对煤炭与煤层气资源开采中所涉及的地下水分布规律预测有一定的参考意义.

关键词：含水量孔隙度含水饱和度煤层三维三分量地震勘探

A facile and general method for synthesis of antibiotic-free protein-based hydrogel:Wound dressing for the eradication of drug-resistant bacteria and biofilms

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Bioactive Materials 2022年第12期7卷 446-458页

作者： Jiang Ouyang Qingyue Bu Na Tao Mingkai Chen Haijun Liu jun Zhou Jinggong Liu bo Deng Na Kong Xingcai Zhang Tianfeng Chen Yihai Cao Wei Tao The First Affiliated Hospital Department of ChemistryJinan UniversityGuangzhou510632China Center for Nanomedicine and Department of Anesthesiology Brigham and Women’s HospitalHarvard Medical SchoolBostonMA02115USA John A.Paulson School of Engineering and Applied Sciences Harvard UniversityCambridgeMA02138USA College of Chemistry and Chemical Engineering Central South UniversityChangshaHunan410083China The Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangdong Provincial Academy of Chinese Medical SciencesGuangzhou510006China Department of Microbiology Tumor and Cell BiologyKarolinska InstituteStockholm17177Sweden

Antibacterial protein hydrogels are receiving increasing attention in the aspect of bacteria-infected-wound healing. However, bacterial drug resistance and biofilm infections lead to hard healing of wounds, thus the construction of biological agents that can overcome these issues is essential. Here, a simple and universal method to construct antibiotic-free protein hydrogel with excellent biocompatibility and superior antibacterial activity against drug-resistant bacteria and biofilms was developed. The green industrial microbicide tetrakis (hydroxymethyl) phosphonium sulfate (THPS) as cross-linking agent can be quickly cross-linked with model protein bovine serum albumin (BSA) to form antibacterial hydrogel through simple mixing without any other initiators, subsequently promoting drug-resistance bacteria-infected wound healing. This simple gelatinization strategy allows at least ten different proteins to form hydrogels (e.g. BSA, human serum albumin (HSA), egg albumin, chymotrypsin, trypsin, lysozyme, transferrin, myohemoglobin, hemoglobin, and phycocyanin) under the same conditions, showing prominent universality. Furthermore, drug-resistance bacteria and biofilm could be efficiently destroyed by the representative BSA hydrogel (B-Hydrogel) with antibacterial activity, overcoming biofilm-induced bacterial resistance. The in vivo study demonstrated that the B-Hydrogel as wound dressing can promote reepithelization to accelerate the healing of methicillin-resistant staphylococcus aureus (MRSA)-infected skin wounds without inducing significant side-effect. This readily accessible antibiotic-free protein-based hydrogel not only opens an avenue to provide a facile, feasible and general gelation strategy, but also exhibits promising application in hospital and community MRSA disinfection and treatment.

关键词： THPS Protein hydrogel Bacterial resistance Anti-Biofilm Wound dressing

Anα/βhydrolase family member negatively regulates salt tolerance but promotes flowering through three distinct functions in rice

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Molecular Plant 2022年第12期15卷 1908-1930页

作者： You-Huang Xiang Jia-jun Yu Ben Liao jun-Xiang Shan Wang-Wei Ye Nai-Qian Dong Tao Guo Yi Kan Hai Zhang Yi-Bing Yang Ya-Chao Li Huai-Yu Zhao Hong-Xiao Yu Zi-Qi lu Hong-Xuan Lin National Key Laboratory of Plant Molecular Genetics CAS Centre for Excellence in Molecular Plant Sciences and Collaborative Innovation Center of Genetics&DevelopmentShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510642China University of the Chinese Academy of Sciences Beijing 100049China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China

Ongoing soil salinization drastically threatens crop growth,development,and yield *** is therefore crucial that we improve salt tolerance in rice by exploiting natural genetic ***,many salt-responsive genes confer undesirable phenotypes and therefore cannot be effectively applied to practical agricultural *** this study,we identified a quantitative trait locus for salt tolerance from the African rice species Oryza glaberrima and named it as Salt Tolerance and Heading Date 1(STH1).We found that STH1 regulates fatty acid metabolic homeostasis,probably by catalyzing the hydrolytic degradation of fatty acids,which contributes to salt ***,we demonstrated that STH1 forms a protein complex with D3 and a vital regulatory factor in salt tolerance,OsHAL3,to regulate the protein abundance of OsHAL3 via the 26S proteasome ***,we revealed that STH1 also serves as a co-activator with the floral integrator gene Heading date 1 to balance the expression of the florigen gene Heading date 3a under different circumstances,thus coordinating the regulation of salt tolerance and heading ***,the allele of STH1 associated with enhanced salt tolerance and high yield is found in some African rice accessions but barely in Asian *** of the STH1HP46 allele from African rice into modern rice cultivars is a desirable approach for boosting grain yield under salt ***,our discoveries not only provide conceptual advances on the mechanisms of salt tolerance and synergetic regulation between salt tolerance and flowering time but also offer potential strategies to overcome the challenges resulted from increasingly serious soil salinization that many crops are facing.

关键词： rice salt tolerance flowering time grain yield fatty acid