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Two dimensional heterostructure： perfect platform for exploring interface interaction

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Science Bulletin 2017年第6期62卷 381-382页

作者： Jiangtan Yuan Weibing Chen jun lou Department of Materials Science and Nano Engineering Rice University Houston TX 77005 USA

Two-dimensional(2D)materials have been attracting great amount of attentions from researchers worldwide due to their exotic mechanical,optical,electrical,thermal and catalytic properties,which could enable their potential applications in future multifunctional *** interests in 2D materials were initially inspired by the successful exfoliation and characterization

关键词： Mo WS

Evaluation of a risk factor scoring model in screening for undiagnosed diabetes in China population

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第10期12卷 846-852页

作者： Jian-jun DONG Neng-jun lou Jia-jun ZHAO Zhong-wen ZHANG Division of Endocrinology Department of Medicine Qilu Hospital of Shandong University Jinan 250012 China Division of Endocrinology Department of Medicine the Second Hospital of Shandong University Jinan 250033 China Division of Endocrinology Department of Medicine Shandong Provincial Qianfoshan Hospital Jinan 250014 China Division of Endocrinology Department of Medicine Provincial Hospital Affiliated to Shandong University Jinan 250021 China

Objective:To develop a risk scoring model for screening for undiagnosed type 2 diabetes in Chinese ***:A total of 5348 subjects from two districts of Jinan City,Shandong Province,China were *** A (2985) included individuals from east of the city and Group B (2363) from west of the *** questionnaires and a standard oral glucose tolerance test (OGTT) were completed by all *** on the stepwise logistic regression analysis of Group A,variables were selected to establish the risk scoring *** validity and effectiveness of this model were evaluated in Group ***:Based on stepwise logistic regression analysis performed with data of Group A,variables including age,body mass index (BMI),waist-to-hip ratio (WHR),systolic pressure,diastolic pressure,heart rate,family history of diabetes,and history of high glucose were accepted into the risk scoring *** risk for having diabetes increased along with aggregate *** Youden index was closest to 1,the optimal cutoff value was set up at *** this point,the diabetes risk scoring model could identify diabetes patients with a sensitivity of 83.3% and a specificity of 66.5%,making the positive predictive value 12.83% and negative predictive value 98.53%.We compared our model with the Finnish and Danish model and concluded that our model has superior validity in Chinese ***:Our diabetes risk scoring model has satisfactory sensitivity and specificity for identifying undiagnosed diabetes in our population,which might be a simple and practical tool suitable for massive diabetes screening.

关键词： Diabetes mellitus Screening Questionnaire Risk factor score

A Genetic Pathway for Tapetum Development and Function in Arabidopsis

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Journal of Integrative Plant Biology 2011年第11期53卷 892-900页

作者： jun Zhu Yue lou Xiaofeng Xu Zhong-Nan Yang College of Life and Environmental Sciences Shanghai Normal University Shanghai 200234 China

In anther development, tapetal cells take part in complex processes, including endomitosis and apoptosis （programmed cell death）. The tapetum provides many of the proteins, lipids, polysaccharides and other molecules necessary for pollen development. Several transcription factors, including DYT1, TDF1, AMS, MS188 and MS1, have been reported to be essential for tapetum development and function in Arabidopsis thaliana. Here, we present a detailed cytological analysis of knockout mutants for these genes, along with an in situ RNA hybridization experiment and double mutant analysis showing that these transcription factors form a genetic pathway in tapetum development. DYT1, TDF1 and AMS function in early tapetum development, while MS188 and MS1 are important for late tapetum development. The genetic pathway revealed in this work facilitates further investigation of the function and molecular mechanisms of tapetum development in Arabidopsis.

关键词： anther development genetic pathway pollen development tapetum transcription factor DYT1 TDF1 AMS MS188 MS1.

Low Temperature DC Sputtering Deposition on Indium-Tin Oxide Film and Its Application to Inverted Top-emitting Organic Light-emitting Diodes

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Journal of Materials Science & Technology 2008年第2期24卷 179-182页

作者： Hui LIN junsheng YU Shuangling lou jun WANG Yadong JIANG State Key Laboratory of Electronic Thin Films and Integrated Devices School of Optoelectronic Information University of Electronic Science and Technology of China （UESTC） Chengdu 610054 China

Indium tin oxide （ITO） ultrathin films were prepared on glass substrate by DC （direct current） magnetron sputtering technique with the assistance of H2O vapor to avoid potential surface damage. The film properties were characterized by X-ray diffraction （XRD） technique, four-point probe method and spectrophotometer. The results show that the deposited ITO film with introduced H2O during sputtering process was almost amorphous. The average visible light transmission of 100 nm ITO film was around 85% and square resistivity was below 80 Ω/square. The film was used as the transparent anode to fabricate an inverted top-emitting organic light-emitting diodes （IT-OLEDs） with the structure of glass substrate/Alq3 （40 nm）/NPB （15 nm）/CuPc （x nm）/ITO anode （100 nm）, where the film thickness of CuPc was optimized. It was found that the luminance of this IT-OLEDs was improved from 25 cd/m^2 to more than 527 cd/m^2 by increasing the thickness of CuPc, and luminance efficiency of 0.24 lm/W at 100 cd/m^2 was obtained, which indicated that the optimized thickness of CuPc layer was around 15 nm.

关键词： Inverted top-emitting organic light-emitting diodes Indium-tin-oxide Ultrathin film DC sputtering

Controls on geomorphic characteristics of the Xiaohei River basin in the upper Lancang-Mekong, China

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Journal of Mountain Science 2020年第5期17卷 1032-1044页

作者： GU Zhen-kui FAN Hui lou jun-peng YANG Kun Yunnan Key Laboratory of International Rivers and Transboundary Eco-Security Institute of International Rivers and Eco-SecurityYunnan UniversityKunming 650091China Department of Hydraulic Engineering Tsinghua UniversityBeijing 10084China

Understanding the evolution of the fluvial geomorphology in an orogenic belt provides valuable insight into the relationship between upper crustal deformation and surface *** upper Lancang-Mekong River is in an area experiencing both uplift and *** related processes provide a steady sediment supply to the lower reaches of the river and play an important role in the regional environmental *** Xiaohei(Weiyuan)River Basin is an important sub-basin in this area,which is characterized by large-scale topographic fluctuations,active tectonics and erosion,and anthropogenic *** different factors introduce numerous complexities to the local surface *** this study,we investigate and quantify the controls of geomorphic evolution of the Xiaohei River *** located and mapped the main knick-zones within the channels and examined the main genetic factors,such as faults and stratigraphic *** results show that the areas with the lowest uplift rates are characterized by a low steepness index and are located in the southeastern part of the *** stream power of the mainstream increases downstream,with an average value of^122 W/*** erosional activity of the various stream channels is ***,the basin tends to expansion,with only local instances of inward *** analysis confirms that a number of the geomorphic evolutionary characteristics of the Xiaohei River Basin are *** addition,the future potential for the increasing the number of dams and the hydropower development in the basin may weaken the expansion trend of the basin over a long period of time.

关键词： Longitudinal profile Steepness Divide migration Stream power Hydropower development Lancang

Establishment of a Lateral Flow Dipstick Detection Method for Influenza A Virus Based on CRISPR/Cas12a System

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China CDC weekly 2024年第37期6卷 946-952,I0008页

作者： Xiaoyan Zhao Ximing Zheng Xiyong Yang Qi Guo Yi Zhang jun lou Department of Clinical Laboratory Zhumadian Central HospitalZhumadian CityHenan ProvinceChina Laboratory of Virology Beijing Key Laboratory of Etiology of Viral Diseases in ChildrenCapital Institute of PediatricsBeijingChina National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

Objective:This study aimed to develop a rapid,visual PCR-CRISPR/Cas12-LFD method for detecting influenza A by utilizing the conserved region of the matrix protein ***:We crafted universal degradation primers and clustered regularly interspaced short palindromic repeats RNA(CRISPR RNA,crRNA)targeting the conserved matrix protein gene of the influenza virus(IFV),integrated with lateral flow dipstick(LFD)*** new PCR-CRISPR/Cas12-LFD approach was designed to determine its sensitivity and specificity through the analysis of various clinical samples collected in ***:The developed nucleic acid assay for influenza A viruses(IAV)demonstrated a sensitivity of 10 copies/μL without cross-reactivity with other respiratory *** of 82 clinical samples showed high concordance with results from fluorescent Polymerase Chain Reaction(PCR),achieving a kappa value of ***:A highly sensitive and specific PCRCRISPR/Cas12-LFD method has been successfully established for the detection of influenza A,offering a robust tool for its diagnosis and aiding in the prevention and control of this virus.

关键词： prevention diagnosis specificity

Ag doped urchin-like α-MnO2 toward efficient and bifunctional electrocatalysts for Li-02 batteries

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Nano Research 2020年第9期13卷 2356-2364页

作者： Linna Dai Qing Sun Lina Chen Huanhuan Guo Xiangkun Nie jun Cheng Jianguang Guo Jianwei Li jun lou Lijie Ci Key Laboratory for Liquid-Solid Structural Evolution&Processing of Materials(Ministry of Education) Research Center for Carbon NanomaterialsSchool of Materials Science and EngineeringShandong UniversityJinan 250061China Department of Materials Science and Nano Engineering Rice UniversityHoustonTexas 77005USA School of Materials Science and Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China

Rechargeable Li-O2 batteries (LOBs) have been receiving intensive attention because of their ultra-high theoretical energy densityclose to the gasoline. Herein, Ag modified urchin-like α-MnO2 (Ag-MnO2) material with hierarchical porous structure is obtained bya facile one-step hydrothermal method. Ag-MnO2 possesses thick nanowires and presents hierarchical porous structure of mesoporesand macropores. The unique structure can expose more active sites, and provide continuous pathways for O2 and discharge productsas well. The doping of Ag leads to the change of electronic distribution in α-MnO2 (i.e., more oxygen vacancies), which playimportant roles in improving their intrinsic catalytic activity and conductivity. As a result, LOBs with Ag-MnO2 catalysts exhibit loweroverpotential, higher discharge specific capacity and much better cycle stability compared to pure a-MnO2. LOBs with Ag-MnO2catalysts exhibit a superior discharge specific capacity of 13,131 mA·h·g^-1 at a current density of 200 mA·h·g^-1, a good cycle stabilityof 500 cycles at the capacity of 500 mA·h·g^-1. When current density is increased to 400 mA·h·g^-1, LOBs still retain a long lifespan of170 cycles at a limited capacity of 1,000 mA·h·g^-1.

关键词： Li-O2 batteries Ag doped urchin-like MnO2 electronic structure cycling stability

Roles of Na^+/Ca^(2+) exchanger 1 in digestive system physiology and pathophysiology

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World Journal of Gastroenterology 2019年第3期25卷 287-298页

作者： Qiu-Shi Liao Qian Du jun lou Jing-Yu Xu Rui Xie Department of Gastroenterology Affiliated Hospital to Zunyi Medical College

The Na^+/Ca^(2+) exchanger(NCX) protein family is a part of the cation/Ca^(2+) exchanger superfamily and participates in the regulation of cellular Ca^(2+) homeostasis. NCX1, the most important subtype in the NCX family, is expressed widely in various organs and tissues in mammals and plays an especially important role in the physiological and pathological processes of nerves and the cardiovascular system. In the past few years, the function of NCX1 in the digestive system has received increasing attention; NCX1 not only participates in the healing process of gastric ulcer and gastric mucosal injury but also mediates the development of digestive cancer, acute pancreatitis, and intestinal *** review aims to explore the roles of NCX1 in digestive system physiology and pathophysiology in order to guide clinical treatments.

关键词： Na^+/Ca^2+exchanger Digestive system diseases Ion channel Sodium Calcium

Single-step fabrication of bionic-superhydrophobic surface using reciprocating-type high-speed wire cut electrical discharge machining

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Chinese Science Bulletin 2014年第28期59卷 3691-3695页

作者： Yan-Ling Wan jun lou Zhan-Jiang Yu Xiao-Zhou Li Hua-Dong Yu College of Mechanical and Electric Engineering Changchun University of Science and Technology

In this work, bionic-superhydrophobic surfaces on aluminum alloy 5083 are fabricated by reciprocatingtype high-speed wire cut electrical discharge machining based on the hydrophobic property of the rice leaf. Submillimeter-scale rectangular grooves are processed on the surfaces. The superhydrophobic surface has shown a static contact angle of 158°, which is similar to the rice leaf. The morphological features are characterized by scanning electron microscopy, showing that the craters and bumps are uniformly distributed on the surfaces of the rectangular grooves with porous nanostructures. The method proposed in this work has the advantages of using only one step,requiring no further procedure to lower the surface energy and processing a large-area surface efficiently.

关键词：超疏水性表面放电加工线切割高速线材仿生扫描电子显微镜制造单步