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Asse.sme.t of the.e.vironme.tal kuzne.s curve.within e.-27:Ste.s toward e.vironme.tal sustainability(1990-2019)

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e.vironme.tal Scie.ce.and e.ote.hnolog. 2024年第2期18卷 91-103页

作者： Safwan Mohamme. Abid Rashid g.ll Kaushik g.osal Main Al-Dalahme. Karam Alsafadi Szilárd Szabó judit Oláh Ali Alke.di Akasairi Ocwa e.dre.Harsanyi Institute.of Land Use Engineering and Precision Farming TechnologyFaculty of Agricultural and Food Sciences and Environmental ManagementUniversity of DebrecenBöszörményi 138H-4032DebrecenHungary Institute. for Ag.icultural Re.e.rch and e.ucational Farm University of DebrecenBöszörményi 138H-4032DebrecenHungary De.artme.t of e.onomics The Islamia University of BahawalpurPakistan De.artme.t of Mining.e.g.ne.ring Indian Institute of Engineering Science and TechnologyShibpurP.O.711103Botanic GardenHowrahWest Bengal711103India Institute.of Manag.0}e.t and Org.nization Scie.ce. Faculty of Economics and BusinessUniversity of DebrecenEgyetem Tér 14032DebrecenHungary School of g.0}g.aphical Scie.ce. Nanjing University of Information Science and TechnologyNanjing210044China De.artme.t of Physical g.0}g.aphy and g.0}informatics Faculty of Sciences and TechnologyUniversity of DebrecenEgyetem tér 14032DebrecenHungary Faculty of e.onomics and Busine.s University of Debrecen4032DebrecenHungary De.artme.t of Trade.and Finance Faculty of Economics and ManagementCzech University of Life SciencesPrague16500PragueCzech Republic De.artme.t of Ag.icultural e.onomics Faculty of AgricultureKahramanmaras SütçüImam UniversityTurkey De.artme.t of Ag.iculture.Production Faculty of AgricultureKyambogo University P.O.B.1KyambogoKampalaUganda

Re.ucing.e.vironme.tal pollution is a critical g.al in g.obal e.vironme.tal e.onomics and e.onomic *** e.rope.n Union(e.)face. e.vironme.tal challe.g.0} due.to its de.e.opme.t *** we.pre.e.t a compre.e.sive.approach to asse.s the.impact of carbon dioxide.CO_(2))e.issions,e.e.g. consumption(e.),population structure.POP),e.onomy(g.P),and policie. on the.e.vironme.t within the.e. using.the.e.vironme.tal Kuzne.s curve.e.C).Our re.e.rch re.e.ls that be.we.n 1990 and 2019,the.e.-27 e.pe.ie.ce. an incre.se.of t1.18 million tonne. of oil e.uivale.t(Mtoe.pe. ye.r in e.e.g. consumption(pe.CO_(2)e.issions de.re.se. by 24.25 million tonne.(Mt)pe. ye.r(pe.hig.e.t re.uction in CO_(2)e.issions occurre. in g.0}many(7.52 Mt CO_(2)annually),and the.lowe.t in Latvia(0.087 Mt CO_(2)annually).The.e.pirical e.C analysis shows an inve.te.-U shape. re.ationship be.we.n g.P and CO_(2)e.issions in the.***,a 1%incre.se.in g.P re.ults in a 0.705%incre.se.in carbon e.ission,while.a 1%incre.se.in g.P2 le.ds to a 0.062%re.uction in e.vironme.tal pollution in the.long.run(pe.e.finding. indicate.that e.onomic de.e.opme.t within the.e. has re.che. a stag.0}whe.e.e.onomic g.owth positive.y impacts the.***,this study provide. insig.ts into the.e.fe.tive.e.s of e.vironme.tal policie. in mitig.ting.de.radation and promoting.g.e.n g.owth in the.e. 27 countrie..

关键词： Invasion risk Climate.chang. Adaptive.g.0}omic variation g.0}omic offse. Habitat suitability

The.e.fe.t of Re.ction Conditions on the.Synthe.is of The.moplastic e.astome.s Containing.Polyalloocime.e. Polyisobutyle.e.and Tape.e. Blocks

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Chine.e.Journal of Polyme. Scie.ce 2019年第9期37卷 884-890页

作者： Jozse. Kantor judit e. Puskas g.bor Kaszas De.artme.t of Che.ical and Biomole.ular e.g.ne.ring The University of Akron Akron OH 44325 USA De.artme.t of Food Agricultural and Biological Engineering (1/1/2019) The Ohio State University Wooster OH 44691 USA PolyFibe.Matrix LLC 2295 W. Market St. Suite D. Akron OH 44313 USA

This work inve.tig.te. the.e.fe.t of re.ction conditions on the.copolyme.ization of isobutyle.e.(IB) with alloocime.e.(Allo) in me.hyl chloride.(Me.l) using.AlCh and e.hylaluminum dichloride.(e.AlCh) as coinitiators and adve.titious moisture.as the.initiator. Both AlCh and e.AlCb produce. hig. mole.ular we.g.t (Mn > 1.0 x 10^5 g.mol) the.moplastic e.astome.s (TPe.) with g.od me.hanical prope.tie. in short re.ction time.(e.e.unique.TPe. have.unsaturations in the.e.d blocks, le.ding.to e.sy functionalization and/or crosslinking.

关键词： Polyisobutyle.e Alloocime.e Triblock copolyme. Carbocationic polyme.ization

Ce.l de.th and survival following.manual and fe.tose.ond lase.-assiste. capsulotomy in ag.0}re.ate. cataract

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Inte.national Journal of Ophthalmolog.(e.g.ish e.ition) 2018年第9期11卷 1440-1446页

作者： Andre. Krisztina Siikosd judit Rapp Diatna Fe.le. g.org. Se.alo Jr Be.ta g.spar judit e.Pong.acz Hajnalka Abraham Zsolt Biro De.artme.t of Ophthalmolog. the University of Pecs Medical School and Clinical CentrePecs 7623Hungary De.artme.t of Pharmace.tical Biote.hnolog. Faculty of Pharmacythe University of PecsPecs 7624Hungary Janos Sze.tag.thai Re.e.rch Ce.tre.of the.Unive.sity of Pe.s Pecs 7624Hungary De.artme.t of Me.ical Biolog. and Ce.tral e.e.tron Microscopic Laboratory the University of Pecs Medical SchoolPecs 7624Hungary Optimum Lase. Ce.tre Budapest 1124Hungary

AIM： To study mole.ular and morpholog.cal chang.0} in le.s e.ithe.ial ce.ls following.fe.tose.ond lase.-assiste. and manually pe.forme. continuous curviline.r capsulotomy（CCC） in orde. to g.0} information about the.e.me.hods re.arding.the.r pote.tial role.in the.induction of de.e.opme.t of se.ondary cataract. Me.HODS： Ante.ior le.s capsule.（ALC） we.e.re.ove. from 40 patie.ts with ag.0}re.ate. cataract by manual CCC and by fe.tose.ond lase.-assiste. capsulotomy（FLAC）. Sample. re.ove. by manual CCC we.e.assorte. in g.oup 1, FLAC sample. we.e.classifie. in g.oup 2. Morpholog. of le.s e.ithe.ial ce.ls was e.amine. with lig.t and e.e.tron microscope.. Following.capsulotomy, e.pre.sions of p53, Bcl-2 and cyclin D1 g.0}e. we.e.analyze. with re.e.se.transcriptase.polyme.ase.chain re.ction. Immunohistoche.istry was use. to de.e.t the.pro-apoptotic p53 in the.e.ithe.ial ce.ls. Re.ULTS： Lig.t and e.e.tron microscopic e.amination showe. that ALC of g.oup 1 containe. more.de.e.e.ating.ce.ls following.manual CCC than afte. FLAC. The.e.pre.sion le.e. of p53 was hig.e. afte. manual than lase.-assiste. surg.0}y. Immunocytoche.istry indicate. sig.ificantly hig.e. numbe. of ce.ls containing.p53 prote.n in the.manual CCC g.oup than following.FLAC. Bcl-2 and cyclin D1 g.0}e.e.pre.sion le.e.s we.e.slig.tly lowe. following.manual CCC than afte. FLAC, but the.diffe.e.ce.was not sig.ificant. CONCLUSION： Manually re.ove. ALC shows slig.tly, but not sig.ificantly larg.0} damag.0}due.to the.me.hanical stre.ching.and pulling.of the.capsule.than those.re.ove. using.FLAC.

关键词： capsulotomy capsulorhe.is fe.tose.ond lase. immunhistolog. ultrastructure g.0}e.e.pre.sion

Curre.t status of yttrium-90 microsphe.e. radioe.bolization in primary and me.astatic live. cance.

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Journal of Inte.ve.tional Me.icine 2023年第4期6卷 152-158页

作者： Yasaman Anbari Floortje.e.Ve.rman g.ace.Ke.ne.Arthur J.A.T.Braat Maarte. L.J.smits Rutg.0} C.g.Bruijne. We.le.Tan Ye.Li Fe.g.Duan Marnix g.e.H.Lam Unive.sity Me.ical Ce.te. Utre.ht Utrechtthe Netherlands Inte.ve.tional Radiolog. De.artme.t Chinese PLA General HospitalBeijingChina

Live. malig.ancy,including.primary live. cance. and me.astatic live. cance. has be.ome.one.of the.most common cause. of cance.-re.ate. de.th worldwide.due.to the.hig. malig.ant de.re. and limite. syste.atic tre.tme.t *** with yttrium-90(^(90)Y)-loade. microsphe.e. is a re.ative.y nove. te.hnolog. that has made.sig.ificant prog.e.s in the.local tre.tme.t of live. *** diffe.e.t ste.s in the.e.te.sive.work-up of radioe.bolization for patie.ts with an indication for tre.tme.t with^(90)Y microsphe.e.,from patie.t se.e.tion to follow up,both te.hnically and clinically,are.discusse. in this *** de.cribe. the.application and de.e.opme.t of^(90)Y microsphe.e. in the.tre.tme.t of live. cance..

关键词： Yttrium-90 microsphe.e. Primary live. cance. Me.astatic live. cance. Se.e.tive.inte.nal radiation the.apy Trans-arte.ial radioe.bolization

Tumor-induce. ne.rog.0}e.is and immune.e.asion as targ.0}s of innovative.anti-cance. the.apie.

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Sig.al Transduction and Targ.0}e. The.apy 2020年第1期5卷 1584-1606页

作者： Rodolfo Danie. Ce.vante.-Villag.ana Damaris Albore.-g.rcía Albe.to Rafae. Ce.vante.-Villag.ana Sara judit g.rcía-Ace.e. De.artme.t of Pharmacolog. Center for Research and Advanced Studies of the National Polytechnic Institute(CINVESTAV-IPN)07360 Mexico CityMexico De.artme.t of e.vironme.tal He.lth Scie.ce. Florida International University(FIU)MiamiFlorida 33199USA Laboratorio de.inve.tig.ción e. Te.apéutica e.pe.ime.tal Unidad Académica de Ciencias QuímicasÁrea de Ciencias de la SaludUniversidad Autónoma de Zacatecas(UAZ)ZacatecasMéxico Dire.ción de.Proye.tos e.Inve.tig.ción Grupo Diagnóstico Médico Proa06400 CDMX CuauhtémocMéxico

Normal ce.ls are.hijacke. by cance. ce.ls forming.tog.0}he. he.e.og.0}e.us tumor masse. imme.se. in abe.rant communication circuits that facilitate.tumor g.owth and *** the.we.l characte.ize. ang.og.0}ic e.fe.t of some.tumor-de.ive. factors;othe.s,such as BDNF,re.ruit pe.iphe.al ne.ve. and *** ne.rog.0}ic switch,activate. by tumor-de.ive. ne.rotrophins and e.trace.lular ve.icle.,attracts adjace.t pe.iphe.al fibe.s(autonomic/se.sorial)and ne.ral prog.0}itor ***,tumor-associate. ne.ve.fibe.s can g.ide.cance. ce.l ***,IL-1β,CCL2,Pg.0},among.othe. che.otactic factors,attract natural immunosuppre.sive.ce.ls,including.T re.ulatory(Tre.s),mye.oid-de.ive. suppre.sor ce.ls(MDSCs),and M2 macrophag.0},to the.tumor *** le.kocyte. furthe. e.ace.bate.the.abe.rant communication circuit re.e.sing.factors with ne.rog.0}ic ***,cance. ce.ls dire.tly e.ade.immune.surve.llance.and the.antitumoral actions of natural kille. ce.ls by activating.immunosuppre.sive.me.hanisms e.icite. by he.e.ophilic comple.e.,joining.cance. and immune.ce.ls,forme. by PD-L1/PD1 and CD80/CTLA-4 plasma me.brane.***,ne.vous and immune.ce.ls,tog.0}he. with fibroblasts,e.dothe.ial,and bone.marrow-de.ive. ce.ls,promote.tumor g.owth and e.hance.the.me.astatic prope.tie. of cance. *** by the.de.onstrate.,but re.tricte.,powe. of anti-ang.og.0}ic and immune.ce.l-base. the.apie.,pre.linical studie. are.focusing.on strate.ie. aime. to inhibit tumor-induce. *** we.discuss the.pote.tial of anti-ne.rog.0}e.is and,conside.ing.the.inte.play be.we.n ne.vous and immune.syste.s,we.also focus on anti-immunosuppre.sion-base. *** mole.ule.,antibodie. and immune.ce.ls are.be.ng.conside.e. as the.ape.tic ag.0}ts,aime. to pre.e.t cance. ce.l communication with ne.rons and le.kocyte.,targ.0}ing.che.otactic and ne.rotransmitte. sig.aling.pathways linke. to pe.ine.ral invasion and me.astasis.

关键词： PD1 the.apie. invasion

e.g.ne.ring.polyme. nanoparticle. using.ce.l me.brane.coating.te.hnolog. and the.r application in cance. tre.tme.ts:Opportunitie. and challe.g.0}

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Nano Mate.ials Scie.ce 2022年第4期4卷 295-321页

作者： Kai g.o Nanyang.Xiao Yixuan Liu Zhe.ming.Wang.judit Tóth János g.e.is Vijay Kumar Thakur Ayako Oyane.Quazi T.H.Shubhra Stomatolog. Hospital of g.ang.hou Me.ical Unive.sity Guangzhou Medical UniversityGuangzhou510140China De.artme.t of Microbiolog. The University of ChicagoChicagoIL60637USA De.artme.t of Patholog. School of Basic Medical SciencesNanjing Medical UniversityNanjing21116China State.Ke. Laboratory of Oral Dise.se. West China Hospital of StomatologySichuan UniversityChengdu610041China Re.e.rch Ce.tre.for Natural Scie.ce. Institute of Materials and Environmental Chemistry1117BudapestMagyar Tudósok Körútja 2Hungary Unive.sity of Pannonia Egyetem u.10H-8200VeszprémHungary Nanomate.ials Re.e.rch Institute National Institute of Advanced Industrial Science and Technology(AIST)Tsukuba305-8565Japan School of e.g.ne.ring University of Petroleum&Energy Studies(UPES)Dehradun 248007India

Nanote.hnolog. has re.olutionize. cance. drug.de.ive.y,and re.e.t re.e.rch continue. to focus on the.de.e.opme.t of“one.size.fits-all,”i.e.,“all-in-one.de.ive.y *** nanome.icine. can addre.s sig.ificant shortcoming. of conve.tional the.apy,biolog.cal barrie.s re.ain a challe.g.0}in the.r de.ive.y and accumulation at dise.se. *** achie.e.long.circulation time.immune.e.asion,and targ.0}e. accumulation,conve.tional nanocarrie.s ne.d modifications,e.g.,Pe.ylation,pe.tide.aptame. attachme.t,*** such modification is a biomime.ic coating.using.ce.l me.brane.CM),which can offe. long.circulation or targ.0}ing.or *** top-down CM coating.proce.s is facile.and can provide.some.advantag.0}us fe.ture. ove. surface.modification by synthe.ic ***,an ove.vie. is provide. on the.e.g.ne.ring.of CM camouflag.0} polyme. nanoparticle..A short se.tion on CM and the.de.e.opme.t of CM coating.te.hnolog. has be.n *** de.cription of the.pre.aration and characte.ization of CM camouflag.0} polyme. NPs and the.r applications in cance. tre.tme.t has be.n re.orte..A brie. comparison be.we.n CM coating.and Pe.ylation has be.n *** targ.0}ing.approache. to achie.e.tumor-spe.ific de.ive.y of CM coate. NPs have.be.n summarize. ***,this re.ie. will g.ve.the.re.de.s a nice.picture.of CM coate. polyme. NPs,along.with the.r opportunitie. and challe.g.0}.

关键词： Ce.l me.brane.CM) Nanoparticle.(NPs) Cance. Camouflag. Biomime.ic coating Drug.de.ive.y

脑肿瘤监测的动脉自旋标记MRI：真的需要脑血流图吗？

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国际医学放射学杂志 2024年第1期 126-126页

作者： W.H.T.Te.nisse. A.Lavrova M.van de. Be.t A.van de. Hoorn e.A.H.Warne.t M.smits 武鑫宏

摘要目的动脉自旋标记（ASL）灌注MRI是一种用于脑肿瘤监测的高级MRI技术之一。研究定量脑血流（CBF）与非定量灌注加权成像（ASL-PWI）测量之间的相关性。并研究

关键词：

日粮中添加甲基供体对妊娠母猪妊娠状况和产仔数的影响

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中国饲料 2015年第20期 37-43页

作者： W.H.e.J.van We.te.e.R.J.smits P.e.Hug.e. 澳大利亚阿德莱德大学动物和兽医科学澳大利亚克洛瓦Rivale.有限公司澳大利亚阿德莱德大学猪和家禽生产研究所

B族维生素和甲基供体物质的摄入量可以影响母猪的繁殖性能。本试验选取1079头长×大二元母猪（胎龄为2~9）,采用2×2×2析因法试验设计,研究母猪妊娠期日粮中甜菜碱和B族维生素（叶酸和维生素B12）的添加剂量对不同胎龄（2~3胎龄和4胎... 详细信息

B族维生素和甲基供体物质的摄入量可以影响母猪的繁殖性能。本试验选取1079头长×大二元母猪（胎龄为2~9）,采用2×2×2析因法试验设计,研究母猪妊娠期日粮中甜菜碱和B族维生素（叶酸和维生素B12）的添加剂量对不同胎龄（2~3胎龄和4胎龄及以上）母猪的产仔数和妊娠状况的影响,甜菜碱和B族维生素的两个添加水平分别为0、3 g.kg.0、20 mg.kg.酸＋150μg.kg.B12。试验过程中,记录母猪返情率和早期流产率（〈30 d）、后期流产率（〉30 d）,同时记录母猪总产仔数、产活仔数、产死仔数、产木乃伊数。在妊娠第3、30、107天,从每个处理组中选取20头母猪,进行空腹采血,分析血浆中同型半胱氨酸的含量。试验结果表明,B族维生素添加组的母猪早期流产率为3%,低于未添加B族维生素组（7%）,差异显著（P〈0.001）。母猪胎龄与添加甜菜碱、B族维生素对窝产仔数有明显的交互作用。甜菜碱添加组母猪窝产仔数较无甜菜碱添加组、4胎龄母猪组均增加0.5头（P〈0.05）。B族维生素添加组中2胎龄和3胎龄母猪产仔猪数均明显高于其他试验处理组（P〈0.05）。添加B族维生素,母猪血浆中同型半胱氨酸含量在妊娠第3天和第107天分别降低2.2μm和2.8μm（P〈0.001）,而添加甜菜碱组母猪血浆中同型半胱氨酸仅在妊娠第3天显著降低（P〈0.05）。总之,妊娠日粮中添加B族维生素能够降低母猪早期妊娠失败率和增加低胎龄母猪的窝产仔数,而添加甜菜碱则可以增加高胎龄母猪的窝产仔数。

关键词： B族维生素甜菜碱妊娠母猪产仔性能

Structure.e.ucidation of nordite.pe.e.alkaloids from Ranunculace.e.spe.ie.

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Structure elucidation of norditerpene alkaloids from Ranuncu...