检索结果-南通市图书馆

Open Journal of Ecology 2016年第9期6卷 517-528页

作者： juan luis Aguirre Carlos Talabante Alejandro Aparicio Manuel Peinado Cátedra de Medio Ambiente Departamento de Ciencias de la Vida Universidad de Alcalá Madrid Spain

This paper describes and analyzes floristic, structural and conservation features of the shrubland occupied by Chersophilus duponti in the northwest corner of its world distribution range. This study relates the coverage, floristic composition with estimated lark density in the area. We identified four types of shrublands, three of them varied significantly in floristic composition for the habitats of this species in contrast with those of their world distribution: Cistus ladanifer scrubs;heaths dominated by Ericaceae, and scrubs dominated by the genera Lavandula, Thymus and Cytisus. The fourth type, dominated by aromatic chamaephytes and grass, fits descriptions of the bird’s typical habitat. The areas sampled are subject to different categories of threats, the most significant being the natural succession process due to the cessation of grazing, reforestation measures and the use of flat areas for farmlands or other uses. The density of larks in this area was directly related to coverage-composition of plant community.

关键词： Alaudidae Passerine Birds Vegetation-Birds Relationships Steppe Birds Conservation Status

Tenofovir vs lamivudine plus adefovir in chronic hepatitis B:TENOSIMP-B study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第41期23卷 7459-7469页

作者： Manuel Rodríguez juan Manuel Pascasio Enrique Fraga Javier Fuentes Martín Prieto Gloria Sánchez-Antolín Jose luis Calleja Esther Molina María luisa garcía-Buey María Angeles Blanco Javier Salmerón María Lucía Bonet Jose Antonio Pons Jose Manuel González Miguel Angel Casado Francisco Jorquera 无 Division of Gastroenterology and Hepatology.Hospital Universitario Central de Asturias Unit for the Clinical Management of Digestive Diseases IBISHospital Universitario Virgen del Rocío Liver Transplantation and Hepatology Unit Gastroenterology ServiceHospital Universitario Reina Sofía Digestive Medicine Service Hospital Universitario Miguel Servet Hepatology Unit Digestive Medicine ServiceHospital Universitari i Politècnic La Fe Hepatology Unit Hospital Universitario Rio Hortega Liver Unit Hospital Universitario Puerta de Hierro de MajadahondaUniversidad Autónoma de Madrid Digestive Medicine Service Hospital Clínico de Santiago de Compostela Liver Unit Hospital Universitario de La Princesa Digestive Medicine Service Hospital General Universitario Gregorio Maranon Digestive Medicine Unit Complejo Hospitalario de Granada Digestive Medicine Service Hospital Universitario Son Espases Hepatology Unit IMIB Hospital Universitario Virgen de la Arrixaca Digestive Medicine Service Hospital Clínico Universitario de Valladolid Pharmacoeconomics and Outcomes Research Iberia Division of Gastroenterology and Hepatology Complejo Asistencial Universitario de León the TENOSIMP-B Research Group

AIM To demonstrate the non-inferiority(15% non-inferiority limit) of monotherapy with tenofovir disoproxil fumarate(TDF) vs the combination of lamivudine(LAM) plus adefovir dipivoxil(ADV) in the maintenance of virologic response in patients with chronic hepatitis B(CHB) and prior failure with *** This study was a Phase IV prospective, randomized, open, controlled study with 2 parallel groups(TDF and LAM+ADV) of adult patients with hepatitis B e antigen(HBe Ag)-negative CHB, prior failure with LAM, on treatment with LAM+ADV for at least 6 mo, without prior resistance to ADV and with an undetectable viral load at the start of the study, in 14 Spanish hospitals. The follow-up time for each patient was 48 wk after randomization, with quarterly visits in which the viral load, biochemical and serological parameters, adverse effects, adherence to treatment and consumption of hospital resources were *** Forty-six patients were evaluated [median age: 55.4 years(30.2-75.2); 84.8% male], including 22 patients with TDF and 24 with LAM+ADV. During study development, hepatitis B virus DNA(HBV-DNA) remained undetectable, all patients remained HBe Ag negative, and hepatitis B surface antigen(HBs Ag) positive. Alanine aminotransferase(ALT) values at the end of the study were similar in the 2 groups(25.1± 7.65, TDF vs 24.22 ± 8.38, LAM+ADV, P = 0.646). No significant changes were observed in creatinine or serum phosphorus values in either group. No significant differences between the 2 groups were noted in the identification of adverse effects(AEs)(53.8%, TDF vs 37.5%, LAM+ADV, P = 0.170), and none of the AEs which occurred were serious. Treatment adherence was 95.5% and 83.3% in the TDF and the LAM+ADV groups, respectively(P = 0.488). The costs associated with hospital resource consumption were significantly lower with the TDF treatment than the LAM+ADV treatment(€4943 ± 1059 vs €5811 ± 1538, respectively, P < 0.001).CONCLUSION TDF monotherapy proved to be safe

关键词： Tenofovir Lamivudine+Adefovir Efficacy Safety Adherence Costs Hepatitis B

Ion channels, phosphorylation and mammalian sperm apacitation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2011年第3期13卷 395-405,511页

作者： Pablo E Visconti Dario Krapf Jose luis de la Vega-Beltran juan Jose Acevedo Alberto Darszon Department of Veterinary and Animal Science Paige Labs University of Massachusets Amherst MA 01003 USA Institute of Molecular and Cell Biology of Rosario （CONICETUNR） and Area Biologia Facultad de Ciencias Biologicas y Farmaceuticas UNR Rosario 2000 Argentina Departamento de Genetica del Desarrollo y Fisiologia Molecular Institute de Biotecnologia Universidad Nacional Autonoma de Mexico （UNAM） Cuemavaca Merelos C.P. 62510 Mexico Departamento de Fisiologia y Farmacologia Facultad de Medicina Universidad Autenoma del Estado de Morelas Cuernavaca C.P. 62510 Mexico

Sexually reproducing animals require an orchestrated communication between spermatozoa and the egg to generate a new individual. Capacitation, a maturational complex phenomenon that occurs in the female reproductive tract, renders spermatozoa capable of binding and fusing with the oocyte, and it is a requirement for mammalian fertilization. Capacitation encompasses plasma membrane reorganization, ion permeability regulation, cholesterol loss and changes in the phosphorylation state of many proteins. Novel tools to study sperm ion channels, image intracellular ionic changes and proteins with better spatial and temporal resolution, are unraveling how modifications in sperm ion transport and phosphorylation states lead to capacitation. Recent evidence indicates that two parallel pathways regulate phosphorylation events leading to capacitation, one of them requiring activation of protein kinase A and the second one involving inactivation of ser/thr phosphatases. This review examines the involvement of ion transporters and phosphorylation signaling processes needed for spermatozoa to achieve capacitation. Understanding the molecular mechanisms leading to fertilization is central for societies to deal with rising male infertility rates, to develop safe male gamete-based contraceptives and to preserve biodiversity through better assisted fertilization strategies.

关键词： capacitation ion channels lipids phosphorylation sperm

Modeling Violence Among and Against University Students in a Mexican Medium-Sized City

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Business Review 2020年第6期19卷 226-239页

作者： Alicia Sylvia Gijón-Cruz Rafael G.Reyes-Morales Blanca Azucena garcía-Ramírez juan luis Bautista-Martínez Nadia Esteva-Duran Universidad Autónoma Benito Juárez de Oaxaca State of OaxacaMexico Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca State of OaxacaMexico

Violence against university students and among them is analyzed on campus and the household as well as the relationships of violence between these two social *** study was undertaken through an anonymous random survey in the two larger public universities in a Mexican medium-sized *** violence and types of violence-verbal,psychological,sexual,and physical-were evaluated by sex and by universities;and the aggressors were identified.A students’concept of violence was built,considering causes of intimate-partner violence,violence in general and ethical judgment on gender ***,it was measured the relationships between violence on campus and in the household using bivariate statistical *** indicate the main aggressors on campus are classmates and professors,whereas in the household are the mother,relatives together with the parents and relatives without the ***-campus,there were found statistically significant associations between professors-aggressors and students as victims of violence by *** the household,the bivariate analysis confirmed mothers as single aggressors and fathers exerting violence together with relatives against student-children;and direct relationships between on-campus(psychological and sexual violence)and domestic(physical and sexual violence).

关键词： types of violence violence by sex aggressors students’concept of violence

Preparation of a ε-caprolactonic diterpenoid derivate by unexpected oxidative cleavage/lactonization of 2-oxoaustroeupatol

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural Products and Bioprospecting 2022年第1期12卷 265-269页

作者： Pablo A.Chacón-Morales juan M.Amaro-luis luis Beltrán Rojas Fermín Rémi Jacquet Denis Deffieux Laurent Pouységu Stéphane Quideau Natural Products Laboratory Department of ChemistryFaculty of ScienceUniversity of Los AndesMérida 5101Venezuela Research Institute Faculty of Pharmacy and BioanalysisUniversity of Los AndesMérida 5101Venezuela ISM(CNRS-UMR 5255) Univ.Bordeaux351 cours de la Libération33405 Talence CedexFrance

From aerial parts of Austroeupatorium inulifolium was isolated the ent-nor-furano triol labdane austroeupatol *** compound 1 was treated with IBX showing an unexpected selectivity at the potentially oxidizable sites of the sub-strate yielding the 2-oxoaustroeupatol(2)and 2,19-dioxoaustroeupatol(3).The treatment of 2 with sodium periodate yields a heterocyclic derivative(ε-caprolactone derivate 4)formed by oxidative cleavage and unexpected intramo-lecular attack of the hydroxymethylene(C-19)oxygen to the ketonic carbon(C-2).A plausible mechanistic pathway for the obtention of compound 4 is proposed.

关键词： Oxidative cleavage Austroeupatol NaIO4 IBX Lactonization NMR

A new market segment for olive oil: Olive oil tourism in the south of Spain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences 2014年第3期5卷 179-185页

作者： Genoveva Millán juan M. Arjona luis Amador Department of Economics Loyola Andalucía University Córdoba Spain Department of Quantitative Methods Loyola Andalucía University Córdoba Spain

Spain is the leading producer of olive oil. For Spain, olive oil and olive growing are not only an important source of economic wealth, but also symbols of its culture and gastronomy renowned both nationally and internationally. However, in rural areas where the olive is the primary source of income for resident families, proposals are being sought for activities that break away from the seasonality in income represented by dependence on agriculture. Among all these proposals there is one that is oleotourism, which is beginning to gain ground because of its facet of culinary tourism. This is due to its uniqueness, and it can also be considered an initiative for sustainable rural tourism. Given the interest aroused by this type of initiative, both on the part of the public administration and also the olive sector, this study involves the demand for oleotourism in Andalucía and is a strategic analysis of oleotourism as a new market sector in the south of Spain.

关键词： Olive Oil Oleotourism Sustainability Andalucía Rural Development

Photodegradation and Removal of Diclofenac by the Green Alga Nannochloropsis oculata

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phyton-International Journal of Experimental Botany 2021年第5期90卷 1519-1533页

作者： Danaé Samara Sánchez-Sandoval Omar González-Ortega Mara Fernanda Navarro-Martínez juan Marcos Castro-Tapia Ramón Fernando garcía de la Cruz Ruth Elena Soria-Guerra Facultad de Ciencias Químicas Universidad Autónoma de San Luis PotosíSan Luis Potosí78210México

The emerging contaminants(ECs)are organic compounds including *** products are consumed in large quantities,favoring their continuous entrance to the environment and affecting the health of living *** is a non-steroidal anti-inflammatory drug with analgesic properties of prolonged *** is the commonest postoperative analgesic,and it is highly consumed without *** recent years,the capability of microalgae to remove pharmaceuticals in water has been tested as a promising *** this work,the removal efficiency of diclofenac(16µg/mL)by the microalga Nannochloropsis oculata CCAP 186/7 was *** major nutrient concentrations in Bold’s Basal Medium were modified(nitrogen and carbon:50 and 100%of their original concentration)to know their effect in the removal of *** degradation by light was also *** maximum removal capacity of diclofenac in the medium was 68.8%.The percentage of diclofenac adsorbed on the cell wall was between 6 and 12.7%.Around 23.6%of diclofenac was degraded by light after 18 *** did not show growth inhibition due to the presence of *** results obtained point to the promissory application of *** as a bioremediation system for diclofenac removal.

关键词： Adsorption emerging contaminants microalgae pharmaceuticals phycoremediation photodegradation

Occurrence data may provide unreliable thermal preferences and breadth of species

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Zoology 2015年第6期61卷 972-982页

作者： Sara VILLEN-PEREZ luis M. CARRASCAL Department of Biogeography and Global Change National Museum of Natural Sciences MNCN-CSIC. C/José Gutiérrez Abascal 2 28006 Madrid Spain.

Accurate information on the thermal preference and specialization of species is needed to understand and predict spe- cies geographical range size and vulnerability to climate change. Here we estimate the position and breadth of species within thermal gradients based on the shape of the response curve of species abundance to temperature. The objective of the study is to compare the measurements of this approach based on abundance data with those of the classical approach using species＇ occur- rence data. The relationship between species＇ relative abundance and minimum winter temperature of 106 bird species wintering in the Iberian Peninsula is modeled at 100 Km2 resolution with quadratic logistic regressions. From these models we calculated the preferred temperature of species as the temperature at which the abundance is maximized, and the thermal breadth of species as the relative area under the temperature-abundance curve. We also estimated the thermal preferences and breadth of species as the average temperature and temperature range of the UTM cells in which the species are present. The abundance-temperature response curves reveal that birds prefer higher temperatures to overwinter, and are more thermally selective, than is measured by the classical approach. Moreover, response curves detect a higher inter-specific variability in both thermal preferences and ther- mal breadth of species. As occurrence data gives the same weight to cells with one or many individuals, the average temperature of the cells in which the species is present roughly reflects the average temperature in the region of study and not the environ- mental preferences of species .

关键词： Abundance-temperature response curve Birds Species occurrence Thermal breadth Thermal preferences Winter

Convergence in leaf phenology traits of two understorey ferns in the northwestern Iberian Peninsula

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Plant Ecology 2018年第1期11卷 92-102页

作者： luis G.Quintanilla Beatriz Pías Department of Biology and Geology Physics and Inorganic ChemistrySchool of Environmental Sciences and TechnologyRey Juan Carlos Universityc/Tulipán s/n28933 MóstolesMóstolesSpain Department of Plant Sciences Faculty of BiologyComplutense of Madrid UniversityMadridSpain

Aims Plants control leaf phenology to maximize annual photosynthetic *** ferns play an important ecological role in many habitats,especially forests,their phenology traits have been poorly ***,we investigate the leaf phenology of two ferns of the forest understorey and analyse the relationship between the timing of leaf emergence and spore dispersal and the effect of between-year climatic *** We compared the leafing and sporing phenologies of two ferns with very large(>2 m),overwintering leaves:Culcita macrocarpa and Woodwardia *** regularly monitored individuals of six popu-lations in the northwestern Iberian Peninsula during a 3-year *** studied eight phenology variables:leafing start date,leafing end date,leaf expansion time,number of new leaves per individual,between-individual synchrony,within-individual synchrony,percentage of fertile leaves and spore release *** also determined leaf mass per area(LMA)and gathered data on air temperature and *** findings Both *** and *** produce few leaves(~2 leaves individual−1 year−1),which expand simultaneously for a very long period(from midwinter to early summer),are retained for more than 1 year(37 and 19 months,respectively)and have relatively high *** traits,together with large leaf size,have also been found in seed plants from the forest understorey and represent adap-tations to this light-limited *** of both study ferns are simultaneously released in late winter,with little between-year variation caused by differences in air *** remarkable similarity between species suggests that the convergence in tim-ing of leaf emergence favours the convergence in timing of spore dispersal.

关键词： Culcita macrocarpa leaf phenology spore dispersal temperate forest Woodwardia radicans

Identifcation of Immunity-related Genes in Arabidopsis and Cassava Using Genomic Data

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genomics, Proteomics & Bioinformatics 2013年第6期11卷 345-353页

作者： luis Guillermo Leal A'lvaro Perez Andre's Quintero A'ngela Bayona juan Felipe Ortiz Anju Gangadharan David Mackey Camilo Lo'pez Liliana Lo'pez-Kleine Department of Statistics Universidad Nacional de Colombia Department of Biology Universidad Nacional de Colombia Department of Molecular Genetics The Ohio State University

Recent advances in genomic and post-genomic technologies have provided the opportu- nity to generate a previously unimaginable amount of information. However, biological knowledge is still needed to improve the understanding of complex mechanisms such as plant immune responses. Better knowledge of this process could improve crop production and management. Here, we used holistic analysis to combine our own microarray and RNA-seq data with public genomic data from Arabidopsis and cassava in order to acquire biological knowledge about the relationships between proteins encoded by immunity-related genes （IRGs） and other genes. This approach was based on a kernel method adapted for the construction of gene networks. The obtained results allowed us to propose a list of new IRGs. A putative function in the immunity pathway was predicted for the new IRGs. The analysis of networks revealed that our predicted IRGs are either well documented or recognized in previous co-expression studies. In addition to robust relationships between IRGs, there is evidence suggesting that other cellular processes may be also strongly related to immunity.

关键词： Arabidopsis Cassava Functional gene prediction Genomic data Kernel canonical correlation ajalysi Plant immunity