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Protection and Control of Modern Power Systems 2023年第2期8卷 85-98页

作者： juan carlos Quispe John Morales Eduardo Orduna Carlo Liebermann Michael Bruhns Peter Schegner Universidad Nacional de San juan-CONICET San JuanArgentina Universidad Tecnológica del Perú LimaPerú Technical University of Dresden DresdenGermany

The ongoing transformation of electrical power systems highlights the weaknesses of the protection schemes of traditional devices because they are designed and configured according to traditional characteristics of the ***,this work proposes a new methodology to study the fault-generated high frequency transient signals in transmission lines through multiresolution *** high frequency components are determined by a new digital filtering technique based on mathematical morphology theory and a spectral energy ***,wide spectra of signals in the time–frequency domain are *** performance of this method is verified on an electrical power system modeled in ATP-Draw,where simulation and test signals are developed for different locations,fault resistances,inception angles,high frequency noises,sampling frequencies,types of faults,and shapes of the structuring *** results show the characteristics of the fault such as the traveling wave frequency,location,and starting time.

关键词： Digital filter High frequency Mathematical morphology Time–frequency Traveling waves

Recent Near-surface Temperature Trends in the Antarctic Peninsula from Observed,Reanalysis and Regional Climate Model Data

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Advances in Atmospheric Sciences 2020年第5期37卷 477-493页

作者： Deniz BOZKURT David HBROMWICH Jorge CARRASCO Keith MHINES juan carlos MAUREIRA and Roberto RONDANELLI Department of Meteorology University of ValparaísoValparaíso 2340000Chile Center for Climate and Resilience Research(CR)2 Santiago 8320000Chile Polar Meteorology Group Byrd Polar and Climate Research CenterThe Ohio State UniversityColumbusOH 43210USA Centro de Investigacion GAIA Antártica Universidad de MagallanesPunta Arenas 6200000Chile Center for Mathematical Modeling(CMM) University of ChileSantiago 8320000Chile Department of Geophysics University of ChileSantiago 8320000Chile

This study investigates the recent near-surface temperature trends over the Antarctic *** make use of available surface observations,ECMWF’s ERA5 and its predecessor ERA-Interim,as well as numerical simulations,allowing us to contrast different data *** use hindcast simulations performed with Polar-WRF over the Antarctic Peninsula on a nested domain configuration at 45 km(PWRF-45)and 15 km(PWRF-15)spatial resolutions for the period 1991?*** addition,we include hindcast simulations of KNMI-RACMO21P obtained from the CORDEX-Antarctica domain(~50 km)for further *** show that there is a marked windward warming trend except during *** windward warming trend is particularly notable in the autumn season and likely to be associated with the recent deepening of the Amundsen/Bellingshausen Sea low and warm advection towards the Antarctic *** the other hand,an overall summer cooling is characterized by the strengthening of the Weddell Sea low as well as an anticyclonic trend over the Amundsen Sea accompanied by northward *** persistent cooling trend observed at the Larsen Ice Shelf station is not captured by ERA-Interim,whereas hindcast simulations indicate that there is a clear pattern of windward warming and leeward ***,larger temporal correlations and lower differences exhibited by PWRF-15 illustrate the existence of the added value in the higher spatial resolution simulation.

关键词： dynamical downscaling cloud computing added value reanalysis Amundsen/Bellingshausen Sea Weddell Sea temperature trend

Low-cost assembly of a cacao crop genome is able to resolve complex heterozygous bubbles

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Horticulture Research 2019年第1期6卷 1176-1188页

作者： Joe Morrissey J.Conrad Stack Rebecca Valls juan carlos Motamayor Mars Chocolate 13601 Old Cutler RoadMiamiFL 33158USA

Cacao(Theobroma cacao)is a tropical tree that produces the essential raw material for *** yields have been stagnant,land use has expanded to provide for increasing chocolate *** genomes of key parents could modernize breeding programs in the remote and under-resourced locations where cacao is *** MinION,a long read sequencer that runs off of a laptop computer,has the potential to facilitate the assembly of the complex genomes of high-yielding F1 ***,we validate the MinION’s application to heterozygous crops by creating a de novo genome assembly of a key parent in breeding programs,the clone Pound *** MinION-only assembly was 20%larger than the latest released cacao genome,with 10-fold greater contiguity,and the resolution of complex heterozygosity and repetitive *** with Illumina short reads brought the predicted completeness of our assembly to similar levels to the previously released cacao genome *** contrast to previous cacao genome projects,our assembly required only a small scientific team and limited *** sequencing and assembly methods could easily be adopted by under-resourced breeding programs,speeding crop improvement in the developing world.

关键词： breeding crops assembly

Reliability of preoperative measurement with standardized templating in Total Knee Arthroplasty

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World Journal of Orthopedics 2013年第4期4卷 287-290页

作者： Daniel Hernandez-Vaquero Ferran Abat juan Sarasquete juan carlos Monllau School of Medicine Department of Orthopaedic Surgery Hospital St Agustín University of Oviedo Department of Orthopaedic Surgery Hospital Santa Creu i Sant Pau University Autonoma

AIM: To investigate the correlation between preoperative measurement in total knee arthroplasty and the prosthetic size implanted. METHODS: A prospective double-blind study of 50 arthroplasties was performed. Firstly, the reliability and correspondence between the size of said measurement and the actual implant utilized was determined. Secondly, the existing correlation between the intra- and interobserver determinations with the intraclass correlation coefficient was analyzed. RESULTS: An overall correspondence of 54%, improving up to 92% when the measured size admitted a difference of one size, was found. Good intra- and interobserver reliability with an intraclass correlation coefficient greater than 0.90(P < 0.001) was also discovered. CONCLUSION: Agreement between the preoperative measurement with standardized acetate templates and the prosthetic size implanted can be considered satisfactory. We thus conclude it is a reproducible technique.

关键词： Total knee arthroplasty Templating Preoperative measurement Prosthetic size Correlation coefficient

Conical tank level control using fractional order PID controllers： a simulated and experimental study

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Control Theory and Technology 2016年第4期14卷 369-384页

作者： Cristian JAUREGUI Manuel A. DUARTE-MERMOUD Rodrigo OROSTICA juan carlos TRAVIESO-TORRES Orlando BEYTIA Electrical Engineering Department and Advanced Mining Technology Center Universidad de Chile Av. Tupper 2007 Casilla 412-3 Santiago Chile Industrial Technologies Department Technological Faculty Universidad de Santiago de Chile Av. El Belloto 3735 Santiago Chile

In this paper, simulated and experimental results on the conical tank level control are presented. PI/PID controllers of integer order （IO） as well as of fractional order （FO） are studied and compared. The tuning parameters are obtained first by using root locus （RL） and Ziegler and Nichols methods, for comparison purposes. Next, particle swarm optimization （PSO） is employed to determine the optimal controllers＇ parameters using as fitness function the integral of the absolute value of tracking error （IAE）. From the experimental results it is concluded that PI/FOPI are the controllers presenting the lowest IAE indexes, whereas PID/FOPID controllers present the lowest energy consumption by the control signal.

关键词： Level control conical tank PID control fractional PID control experimental control

Smart Contract to Traceability of Food Social Selling

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Computers, Materials & Continua 2023年第3期74卷 4703-4728页

作者： Cristian Valencia-Payan JoséFernando Grass-Ramírez Gustavo Ramirez-Gonzalez juan carlos Corrales University of Cauca Calle 5#4-70190003Popayan-CaucaColombia

Traditionally,food sustainability has been considered solely in the stage of agricultural ***,globalization,the expansion of the food production industry,and the emergence of supermarket chains that control the retail food market require specific significant changes in supply chains in the food sector and,therefore,we need to address the economic,social,and environmental impacts of these *** the other hand,social selling has increased rapidly in recent years,with a further boom,following current events related to the coronavirus disease(COVID-19).This explosion of social sales,where there are usually no control and regulation entities,can bring problems associated with mishandling *** this paper,we expose how Blockchain technology supports the traceability of social sales by validating the data provided by the chain participants such as digital health passports,production and transport data in the sale process;the proposed solution generates recommendations on productmanagement considering the agreements previously made by the network *** evaluate the proposed smart contracts,we useHyperledger Caliper,obtaining an average throughput of 12.6 transactions per second and an average latency of 0.3 s for the asset update *** also use a study case to evaluate the proposed project platform’s selling-transport stage using Internet of Things(IoT)sensors.

关键词： Blockchain reliability smart contracts social selling traceability artisan sweets

First progeria monkey model generated using base editor

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Protein & Cell 2020年第12期11卷 862-865页

作者： Pradeep Reddy Yanjiao Shao Reyna Hernandez-Benitez Estrella Nunez Delicado juan carlos Izpisua Belmonte Gene Expression Laboratory Salk Institute for Biological Studies10010 North Torrey Pines RoadLa JollaCA 92037USA Universidad Catolica San Antonio de Murcia(UCAM) Campus de los JerdnimosN°13512Guadalupe 30107Spain

In this issue,Wang et *** on the generation of a nonhuman primate model of Hutchinson-Gilford progeria syndrome(HGPS)using a base *** editing is an emerging novel genome editing technique for modifying a single base pair at specific sites in the *** editors(BEs)have two prin cipal comp orients,a catalytically in active or single strand cleaving Cas-variant,which binds to the guide RNA and a nucleobase deaminase domain to convert specific base pairs at the target loci(Komor et al.,2016;Nishida et al.,2016;Gaudelli et al.,2017).Cytosine base editor(CBE)and adenine base editor(ABE)are two baseeditors,which con vert Cytosi ne-Gua nine(C-G)to Thymine-Adenine(T-A)and A-T to G-C,respectively.

关键词： base convert editor

Novel insights into D-Pinitol based therapies:a link between tau hyperphosphorylation and insulin resistance

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Neural Regeneration Research 2024年第2期19卷 289-295页

作者： Dina Medina-Vera Antonio Jesús López-Gambero juan Antonio Navarro carlos Sanjuan Elena Baixeras juan Decara Fernando Rodríguez de Fonseca Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND UGC Salud MentalMálagaSpain Facultad de Ciencias Universidad de MálagaMálagaSpain CIBER Enfermedades Cardiovasculares(CIBERCV) Hospital Universitario Virgen de la VictoriaUGC del CorazónMálagaSpain University of Bordeaux INSERMNeurocentre MagendieBordeauxFrance Euronutra S.L.Calle Johannes Kepler MálagaSpain Departamento de Bioquímica y Biología Molecular Facultad de MedicinaUniversidad de MálagaMálagaSpain

Alzheimer’s disease is a neurodegenerative disorder characterized by the amyloid accumulation in the brains of patients with Alzheimer’s *** pathogenesis of Alzheimer’s disease is mainly mediated by the phosphorylation and aggregation of tau *** the multiple causes of tau hyperphosphorylation,brain insulin resistance has generated much attention,and inositols as insulin sensitizers,are currently considered candidates for drug *** present narrative review revises the interactions between these three elements:Alzheimer’s disease-tau-inositols,which can eventually identify targets for new disease modifiers capable of bringing hope to the millions of people affected by this devastating disease.

关键词： Alzheimer’s disease cyclin-dependent kinase 5 diabetes D-Pinitol inositols insulin resistance kinases phosphorylation PI3K/Akt tau

Comparison of biological fitness in crosses between subspecies of Meccus phyllosomus （Hemiptera： Reduviidae： Triatominae） in southern Mexico

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Insect Science 2017年第1期24卷 114-121页

作者： Jose Alejandro Martinez-Ibarra Benjamin Nogueda-Torres Luis Fernando Salazar-Montano juan carlos Garcia-Lino Demver Arroyo-Reyes juan Angel Hernandez-Navarro Area de Entomologia Medica Universidad de Guadalajara Ciudad Guzman Jalisco Mexico Becario de COFAA Escuela Nacional de Ciencias Biologicas Instituto Politecnico Nacional D.F. Mexico Carrera de Medicina Departamento de Salud y Bienestar Centro Universitario del Sur Universidad de Guadalajara Ciudad Guzman Jalisco Mexico

Understanding the biological parameters of some triatomine subspecies of Meccus phyllosomus （Burmeister） is a crucial first step in estimating the epidemiologie importance of this group. Biological parameters related to hatching, lifetime, number of blood meals to molt, percentage of females at the end of the cycle, number of laid eggs, and mortality for each instar of 3 M. phyllosomus subspecies [M. p. mazzottii （Usinger）, M. p. pallidipennis （Stal）, and M. p. phyllosomus] and their laboratory hybrids were evaluated and compared. No significant differences （P 〉 0.05） were found among the experimental hybrids （MaPa, MaPhy, PaPhy） and reciprocal cohorts. In 5 （hatching, number of blood meals to molt, accumulative mortality, percentage of females, and mean number of laid eggs） of the 6 studied parameters （with the exception of development time）, the hybrid cohorts had better fitness results than the parental cohorts involved in each set of crosses. The increase in hybrid fitness found in our study could lead to an increase in the epidemiologic risks caused by transmission of Trypanosoma cruzi to humans.

关键词： biological parameters Chagas disease Meccus subspecies Mexico tri- atomines Trypanosoma cruzi transmission

Symptomatic accommodative and binocular dysfunctions from the use of flat-panel displays

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International Journal of Ophthalmology(English edition) 2018年第3期11卷 501-505页

作者： Esteban Porcar juan carlos Montalt Alvaro M. Pons Enrique Espana-Gregor Department of Optics Optometry and Vision Sciences Physics College University of Valencia Burjassot (Valencia) 46100 Spain Department of Surgery Ophthalmology Unit Faculty of Medicine and Odontology la Fe University and Polytechnic Hospital Valencia 46026 Spain

AIM： To determine the presence of symptomatic accommodative and non-strabismic binocular dysfunctions （***） in a non-presbyopic population of video display unit （VDU） users with flat-panel displays. METHODS： One hundred and one VDU users, aged between 20 to 34y, initially participated in the study. This study excluded contact-lens wearers and subjects who had undergone refractive surgery or had any systemic or ocular disease. First, subjects were asked about the type and nature of eye symptoms they experienced during VDU use. Then, a thorough eye examination excluded those subjects with a significant uncorrected refractive error or other problem, such as ocular motility disorders, vertical deviation, strabismus and eye diseases. Finally, the remaining participants underwent an exhaustive assessment of their accommodative and binocular vision status. RESULTS： Eighty-nine VDU users （46 females and 43 males） were included in this study. They used flat-panel displays for an average of 5±1.9h a day. Twenty subjects presented *** （22.5%）. Convergence excess was the most frequent non-strabismic binocular dysfunction （9 subjects）, followed by fusional vergence dysfunction （3 subjects） and convergence insufficiency （2 subjects）. Within the accommodative dysfunctions, accommodative excess was the most common （4 subjects）, followed by accommodative insufficiency （2 subjects）. Moderate to severe eye symptoms were found in 13 subjects with ANSBD. CONCLUSION： Significant eye symptoms in VDU users with accommodative and/or non-strabismic binocular dysfunctions often occur and should not be underestimated; therefore, an appropriate evaluation of accommodative and binocular vision status is more important for this population,

关键词： general binocular dysfunctions accommodativedysfunctions non-strabismic binocular dysfunctions eyesymptoms video display unit