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Radial Pulse and Electrocardiography Modulation by Mild Thermal Stresses Applied to Feet: An Exploratory Study with Randomized, Crossover Design

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Chinese Journal of Integrative Medicine 2020年第4期26卷 299-306页

作者： Jang-Han Bae Boncho Ku Young ju jeon Hyunho Kim Jihye Kim Haebeom Lee Jong Yeol Kim Jaeuk U.Kim Korea n Medici ne Fun dame ntal Research Divisi on Korea Institute of Oriental MedicineDaejeon(34054)Republic of Korea Department of Biofunctional Medicine and Diagnostics College of Korea n MedicineKyung Hee UniversitySeoul(02453)Republic of Korea Department of Human Informatics of Korean Medicine Interdisciplinary ProgramsKyung Hee UniversitySeoul(02453)Republic of Korea

Objective:To investigate the changes in radial pulse induced by thermal stresses(TSs).Methods:Sixty subjects were *** an open-label,2x2 crossover randomization design,both feet of each subject were immersed in 15%:water for cold stress(CS)and in 40 X:water for heat stress(HS)for 5 min *** pulse,respiration and electrocardiogram(ECG)signals were recorded before,during and immediately after the ***:The an alysis of heart rate variability revealed that CS in creased the low-freque ncy(LF)and high-frequency(HF)components(P<0.05)and that HS reduced the LF and HF components(P<0.01).Both TSs reduced the normalized LF,increased the normalized HF,and reduced the LF/HF *** differences in the ECG signals were more dominant during the TS sessions,but those in the radial pulse signals became more domi nant immediately after the TS sessi *** decreased the pulse depth(P<0.01)and in creased the radial augme ntation in dex(P<0.1),and HS in creased the pulse pressure(P<0.1)and sube ndocardial viability ratio(P<0.01).There were no significant differences in pulse rate during the three time sequences of each *** respiration rate was increased(P<0.1),and the pulse rate per respiration(P/R ratio)was significantly decreased(P<0.05)with *** HF region(10-30 Hz)of the pulse spectral density was suppressed during both ***:CS induced vasoconstriction and sympathetic reactions,and HS induced vasodilation and parasympathetic reacti *** on defi nitions used in pulse diag no sis,we made the novel discoveries that the pulse became slower(decreased P/R ratio),more floating and tenser under CS and that the HF region of the spectral power decreased significantly under both TSs.

关键词： radial pulse pulse diag no sis thermal stress electrocardiography heart rate variability

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Bispectral index monitoring as an adjunct to nurse-administered combined sedation during endoscopic retrograde cholangiopancreatography

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World Journal of Gastroenterology 2012年第43期18卷 6284-6289页

作者： Se Young Jang Hyun Gu Park Min Kyu jung Chang Min Cho Soo Young Park Seong Woo jeon won Young Tak Young Oh Kweon Sung Kook Kim Young Hoon jeon Department of Internal Medicine Kyungpook National University School of Medicine Daegu 700-721 South Korea Department of Anesthesiology and Pain Medicine Kyungpook National University School of Dentistry Daegu 700-721 South Korea

AIM:To determine whether bispectral index (BIS) monitoring is useful for propofol administration for deep sedation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS:Fifty-nine consecutive patients with a variety of reasons for ERCP who underwent the procedure at least twice between 1 july 2010 and 30 November 2010. This was a randomized cross-over study, in which each patient underwent ERCP twice, once with BIS monitoring and once with control monitoring. Whether BIS monitoring was done during the first or second ERCP procedure was random. Patients were intermittently administered a mixed regimen including midazolam, pethidine, and propofol by trained nurses. The nurse used a routine practice to monitor sedation using the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale or the BIS monitoring. The total amount of midazolam and propofol used and serious side effects were compared between the BIS and control groups. RESULTS:The mean total propofol dose administered was 53.1 ± 32.2 mg in the BIS group and 54.9 ± 30.8 mg in the control group (P = 0.673). The individual propofol dose received per minute during the ERCP procedure was 2.90 ± 1.83 mg/min in the BIS group and 3.44 ± 2.04 mg in the control group (P = 0.103). The median value of the MOAA/S score during the maintenance phase of sedation was comparable for the two groups. The mean BIS values throughout the procedure (from insertion to removal of the endoscope) were 76.5 ± 8.7 for all 59 patients in using the BIS monitor. No significant differences in the frequency of < 80% oxygen saturation, hypotension (< 80 mmHg), or bradycardia (< 50 beats/min) were observed between the two study groups. Four cases of poor cooperation occurred, in which the procedure should be stopped to add the propofol dose. After adding the propofol, the procedure could be conducted successfully (one case in the BIS group, three cases in the control group). The endoscopist rated patient sedation as exc

关键词： Conscious sedation Bispectral index monitors Pancreatic neoplasm Endoscopic retrograde cholangiopancreatography

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Effect of geogrid reinforcement on soft and medium dense soils

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Journal of Central South University 2011年第5期18卷 1638-1645页

作者： jeon Sang-Soo Department of Civil Engineering Construction Technology Research CenterINJE UniversityObang-dong 607KimhaeKyungsangnam-Do #621-749South Korea

The field tests were carried out to examine the reinforcement effect of a geogrid on various conditions of embankment height,the number of passages of vibratory roller,the number of reinforced layer of geogrid,and soil *** test results of the dynamic earth pressure indicate that the soil reinforced by geogrid is very effective to increase the stiffness of soil,especially in soft *** dynamic earth pressure ratio,which is defined as the ratio of dynamic earth pressure to self weight of soils,exponentially decreases as the embankment height *** dynamic earth pressure ratio increases up to 80% for soft soils reinforced by both one layer of geogrid in place of no reinforced soils and two layers in place of a single layer of geogrid.

关键词： dynamic earth pressure geogrid reinforced soils repetitive loading

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Pull-out tests and slope stability analyses of nailing systems comprising single and multi rebars with grouted cement

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Journal of Central South University 2012年第1期19卷 262-272页

作者： Sang-Soo jeon Construction Technology Research Center Department of Civil EngineeringInje UniversityObang-dong 607KimhaeKyungsangnam-Do #621-749Korea

The pull-out capacities for soil nailing systems comprising of one single 29 mm diameter(type A) and four 16 mm diameter(type B) rebars with grouted cement were examined.A field test and numerical analysis for the type A and type B systems were carried out to investigate the pull-out capacities and the slope stability reinforcement efficiency in soil and rock *** results of the pull-out tests show the mobilized shear force and load transfer characteristics with respect to soil *** load-displacement relationship was examined for both type A and type B *** stability analyses were carried out to study the relationships between soil and nail reinforcement and bending stiffness as well as combined axial tension and shear *** of safety were calculated in relation to the number of nails and their outside *** soil and rock slopes were included in this evaluation.

关键词： soil nailing bending resistance pull-out test finite difference method

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Metabolic relationships between marine red algae and algae‑associated bacteria

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Marine Life Science & Technology 2024年第2期6卷 298-314页

作者： Kyung Hyun Kim jeong Min Kim ju Hye Baek Sang Eun jeong Hocheol Kim Hwan Su Yoon Che Ok jeon Department of Biological Sciences and Biotechnology Hannam UniversityDaejon 34054Republic of Korea Department of Life Science Chung-Ang UniversitySeoul 06974Republic of Korea Department of Biological Sciences Sungkyunkwan UniversitySuwon 16419Republic of Korea

Mutualistic interactions between marine phototrophs and associated bacteria are an important strategy for their success-ful survival in the ocean,but little is known about their metabolic ***,bacterial communities in the algal sphere(AS)and bulk solution(BS)of nine marine red algal cultures were analyzed,and Roseibium and Phycisphaera were identified significantly more abundantly in AS than in *** metabolic features of Roseibium RMAR6-6(isolated and genome-sequenced),Phycisphaera MAG 12(obtained by metagenomic sequencing),and a marine red alga,Porphyridium purpureum CCMP1328(from GenBank),were analyzed ***6-6 has the genetic capability to fix nitrogen and produce B vitamins(B1,B2,B5,B6,B9,and B12),bacterioferritin,dimethylsulfoniopropionate(DMSP),and phenylacetate that may enhance algal growth,whereas MAG 12 may have a limited metabolic capability,not producing vitamins B9 and B12,DMSP,phenylacetate,and siderophores,but with the ability to produce bacitracin,possibly modulating algal *** CCMP1328 lacks the genetic capability to fix nitrogen and produce vitamin B12,DMSP,phenylacetate,and *** was shown that the nitrogen-fixing ability of RMAR6-6 promoted the growth of ***-pureum,and DMSP reduced the oxidative stress of *** metabolic interactions between strain RMAR6-6 and *** CCMP1328 were also investigated by the transcriptomic analyses of their monoculture and *** together,potential metabolic relationships between Roseibium and *** were *** study provides a bet-ter understanding of the metabolic relationships between marine algae and algae-associated bacteria for successful growth.

关键词： Metabolic relationship Marine red algae Symbiotic bacteria Roseibium Phycisphaera Porphyridium

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富血小板血浆促进创面愈合的细胞和分子机制

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中国组织工程研究 2025年第13期29卷 2793-2801页

作者：龙晨艳程飚田举广东医科大学第一临床医学院广东省湛江市524000 广东医科大学中山市人民医院烧伤整形美容科广东省中山市528400 南部战区总医院烧伤整形科广东省广州市510030

背景:尽管富血小板血浆在促进创面愈合方面显示出治疗潜力,但其临床应用仍需要进一步的研究和验证。此外,对于富血小板血浆作用的机制仍存在一些争议和不确定性。目的:通过对富血小板血浆促进创面愈合的机制进行概述和分析,以增进对该... 详细信息

背景:尽管富血小板血浆在促进创面愈合方面显示出治疗潜力,但其临床应用仍需要进一步的研究和验证。此外,对于富血小板血浆作用的机制仍存在一些争议和不确定性。目的:通过对富血小板血浆促进创面愈合的机制进行概述和分析,以增进对该治疗方法的理解,为未来的基础研究和临床应用提供有益的指导。方法:在中国知网、PubMed数据库检索2000年1月至2023年12月发表的相关文献。英文检索词为“platelet rich plasma,PRP,wound,wound healing,refractory wounds,chronic wounds,cellular and molecular mechanisms,signaling pathways,regenerative medicine”,中文检索词为“富血小板血浆,PRP,创面,伤口,创面愈合,难愈性创面,慢性创面,细胞和分子机制,信号通路,再生医学”。根据纳入和排除标准,最终对80篇文献进行综述。结果与结论:①富血小板血浆在创面愈合中具有许多潜在的优势,它能够提供丰富的生长因子和细胞因子等生物活性物质;②富血小板血浆可以调节参与创面愈合的各种细胞类型的功能,包括表皮细胞、血管内皮细胞、成纤维细胞、干细胞和炎症细胞等;③在富血小板血浆疗法中,细胞外囊泡、线粒体对于创面愈合可能扮演着重要角色;④负载富血小板血浆水凝胶可广泛用于增强组织再生和作为药物传递的功能性载体;⑤富血小板血浆对创面细胞外基质合成和降解起调节作用,从而影响伤口愈合过程中基质重建;⑥富血小板血浆可能通过动态调节多种信号通路和上皮间质转化来影响组织修复与再生,从而为创面愈合的研究提供了全新的视角。

关键词：富血小板血浆生长因子创面愈合细胞和分子机制信号通路再生医学

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Damage Pattern Recognition of Spatially Distributed Slope Damages and Rainfall Using Optimal GIS Mesh Dimensions

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Journal of Mountain Science 2014年第2期11卷 336-344页

作者： Sang-Soo jeon Department of Civil & Urban Engineering Inje University

Damage assessment for slopes using geographical information system(GIS) has been actively carried out by researchers working on several government organizations and research institutes in Korea. In this study, 596 slope damages were examined to identify the types of damage associated with dip angles, dip directions, and heavy rainfall resulting from typhoons in South Korea. Heavy rainfall of 100 mm to 300 mm resulted in 80% at the investigated slope damages. A GIS database was developed for highways, rainfall, soil or rock geometry, and types of damage. A grid of rainfall intensity was generated from the records of maximum daily rainfall. Contours for slope damages and heavy rainfall using optimal GIS mesh dimensions were generated to visualize damage patterns and show substantially strong correlation of rainfall with slope damages. The combination of remote sensing with the GIS pattern recognition process described in this work are being expanded for a new generation of emergency response and rapid decision support systems.

关键词： Damage assessment Slope damages Rainfall GIS Typhoon

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Roadbed behavior subjected to tilting-train loading at rail joint and continuous welded rail

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Journal of Central South University 2014年第7期21卷 2962-2969页

作者： jeon Sang-Soo Department of Civil&Urban Engineering Inje University

The tilting-train is very attractive to the railroad users in the world due to the advantage of high speed in curved track using pre-existing infrastructure of ***-train has a unique allowable speed and mechanism especially in curved *** this work,when tilting-train is operated with the allowable speed,the behavior of roadbed is evaluated by examining its settlement and bearing ***,the stability of roadbed is estimated as the roadbed is in the condition of soft soil influenced by the weather effects and cyclic train *** results show that the roadbed settlement satisfies the allowable settlement when the elastic moduli of upper roadbed and in-situ soil are greater than 3800 and 4600 kN/m2 for rail joint and 2300 and 3300 kN/m2 for continuous welded rail(CWR).

关键词： railway roadbed tilting-train bearing capacity settlement

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Combined silicosis and mixed dust pneumoconiosis with rapid progression: A case report and literature review

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World Journal of Clinical Cases 2018年第16期6卷 1164-1168页

作者： Hee-Young Yoon Yookyung Kim Heae Surng Park Chung-won Kang Yon ju Ryu Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine Ewha Womans University Department of Radiology Ewha Womans University College of Medicine Department of Pathology Ewha Womans University College of Medicine Department of Occupational and Environmental Medicine Ewha Womans University College of Medicine

BACKGROUND Rapidly progressive pneumoconiosis(RPP) occasionally occurs in coal workers, particularly those with high exposure to silica. Here, we report the case of a 64-year-old male miller with RPP. CASE SUMMARY The patient had a persistent cough for one month and had been clinically diagnosed with pulmonary tuberculosis in 2011. He worked in a stone processing factory from the ages of 20 through 37 and has owned his own mill for the past 25 years. His chest radiograph showed significant increases in the size and number of lung nodules since his last follow-up in 2013. By percutaneous needle lung biopsy, the nodular lesions showed diffuse infiltration of phagocytic macrophages and birefringent crystals by polarizing microscopy. He was finally diagnosed with RPP of mixed dust pneumoconiosis combined with silicosis. CONCLUSION In this case, mixed dust pneumoconiosis with silicosis might be accelerated by persistent exposure to graindust from working in a mill environment.

关键词： Pathology Case report Pneumoconiosis Silicosis Dust Occupational diseases

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A New Efficient Synthetic Method for 3-1odothyronamine and Its Potent Hypothermic Efficacy

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Chinese Journal of Chemistry 2011年第10期29卷 2205-2208页

作者： Kim, Joong-Gon Song, Young-Kyu jeon, Su-Yeon Lim, Ye-Ji ju, Hyunwo Choi, Inho Chung, Chan-Moon Biotechnology Division Hanwha Chemical R＆D Center Daejeon 305-345 Korea Department of Chemistry and Medical Chemistry Yonsei University Wonju Gangwon-do 220- 710 Korea Department of Biological Science and Technology Yonsei University Wonju Gangwon-do 220-710 Korea

We developed a new efficient synthetic method for a 3-iodothyronamine （TjAM） that has advantages of less synthetic steps and much higher overall yield compared to those in the conventional method. Our animal study s... 详细信息

关键词： 3-iodothyronamine hibernation-like state ICR mouse

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