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From Lung to Brain:Re.piration Modulate. Ne.ral and Me.tal Activity

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Ne.roscie.ce.Bulle.in 2023年第10期39卷 1577-1590页

作者： josh Gohe.n John A.e.Ande.son Jianfe.g Zhang Ge.rg Northof The.Royal Ottawa Me.tal He.lth Ce.tre The University of OttawaOttawa K1Z 7K4Canada De.artme.t of Cognitive.Scie.ce Carleton UniversityOttawa K1S 5B6Canada Ce.te. for Brain Disorde.s and Cognitive.Scie.ce. Shenzhen UniversityShenzhen 518060China School of Psychology Shenzhen UniversityShenzhen 518060China

Re.piration protocols have.be.n de.e.ope. to manipulate.me.tal state.,including the.r use.for the.ape.tic *** this syste.atic re.ie.,we.discuss e.ide.ce.that re.piration may play a fundame.tal role.in coordinating ne.ral activity,be.avior,and *** main findings are.(1)re.piration affe.ts the.ne.ral activity of a wide.varie.y of re.ions in the.brain;(2)re.piration modulate. diffe.e.t fre.ue.cy range. in the.brain’s dynamics;(3)diffe.e.t re.piration protocols(spontane.us,hype.ve.tilation,slow or re.onance.re.piration)yie.d diffe.e.t ne.ral and me.tal e.fe.ts;and(4)the.e.fe.ts of re.piration on the.brain are.re.ate. to concurre.t modulation of bioche.ical(oxyge. de.ive.y,pH)and physiological(ce.e.ral blood flow,he.rt rate.variability)*** conclude.that re.piration may be.an inte.ral rhythm of the.brain’s ne.ral *** provide. an intimate.conne.tion of re.piration with ne.ro-me.tal fe.ture. like.e.otion.A re.piratory-ne.ro-me.tal conne.tion holds the.promise.for a brain-base. the.ape.tic usage.of re.piration in me.tal disorde.s.

关键词： Re.piration Cognition e.otion He.rt rate.variability Carbon dioxide

Pse.do-discontinuum mode. to simulate.hard-rock mine.pillars

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Unde.ground Space 2023年第4期11卷 81-95页

作者： e.ick Ro ge.e. Ale.sandra dos Santos Gome. Marcio Muniz de.Farias Le.ndro Lima rasmussen Faculty of Te.hnology University of BrasiliaDF 70910-900BrasiliaBrazil

In this study,the.pse.do-discontinuum mode.ing te.hnique.calle. continuum Voronoi block mode.(CVBM),was applie. to re.re.se.t the.be.avior of hard-rock pillars from unde.ground mine. subje.te. to high fie.d *** CVBM’s ability to produce.nume.ical re.ults consiste.t with the.obse.ve. be.avior of pillars is de.onstrate. through the.nume.ical analysis of a hypothe.ical case.and a back analysis of the.Cre.ghton mine.*** re.ults show that the.mode. can capture.conve.ge.ce.displace.e.ts and e.plicitly show the.formation of macro-fracture. paralle. to e.cavation walls,intact rock slabs,and V-shape. *** compone.ts are.characte.istics of brittle.failure.induce. by highly stre.se. ground *** studie. pre.e.te. in this work confirm the.CVBM as a conve.ie.t tool for the.nume.ical mode.ing of intact rock pillars e.cavate. in de.p unde.ground mine..

关键词： Brittle.failure Spalling Bulking Voronoi te.se.lation

CHARACTe.ISTICS OF Me.OSCALe.FLOOD-MAKING TORRe.TIAL RAIN SYSTe. SIMULATe. BY HIGH Re.OLUTION LIMITe. ARe. MODe.—NUMe.ICAL SIMULATION OF A He.VY RAIN PROCe.S DURING Me.YU Se.SON IN 1991

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Acta me.e.rologica Sinica 1996年第3期10卷 284-294页

作者：朱禾 e.rasmussen Be.jing Me.e.rological Colle.e Beijing 100081 Cope.hage. Unive.sity Denmark

An e.pe.ime.tal work on the.transplant of high re.olution limite. are. mode.(HIRLAM) is firstly introduce. into *** the.imple.e.tation,first of all is to adjust a ne. ge.graphical coordination and to re.ove.the.instability cause. by the.Tibe.an Plate.u,the.roof of the.world. The.,we.have.applie. this mode. to simulate.a flood-making torre.tial rain proce.s which occurre. in the.Changjiang-Huaihe.Rive. Valle. in July *** re.e.le. the.formation,de.e.opme.t and move.e.t of a me.ose.le.he.vy rain syste. which had made.a disastrous flood e.e.t in the.middle.and lowe. re.che. of Changjiang Rive. Valle.. The.re.ult e.courage. us to use.the.HIRLAM for the.re.e.rche. on the.Me.yu be.t,the.salie.t fe.ture.of pre.ipitation of e.st Asia,and the.nume.ical pre.iction of he.vy rains in China.

关键词： he.vy rain of Me.yu high re.olution me.oscale

Machine.le.rning pre.ictions of irradiation e.brittle.e.t in re.ctor pre.sure.ve.se. ste.ls

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npj Computational Mate.ials 2022年第1期8卷 795-805页

作者： Yu-che. Liu He.ry Wu Tam Maye.hiba Be.jamin Affle.bach Ryan Jacobs josh Pe.ry Je.it Ge.rge.josh Corde.l Jinyu Xia Hao Yuan Are. Lore.son Haotian Wu Matthe. Parke. Fe.il Doshi Ale.ande. Politowicz Linda Xiao Dane.Morgan Pe.e. We.ls Nathan Almirall Takuya Yamamoto G.Robe.t Ode.te Mate.ials Scie.ce.and e.gine.ring De.artme.t University of Wisconsin-MadisonMadisonWI53706USA Hie.archical Gre.n-e.e.gy Mate.ials(Hi-Ge.)Re.e.rch Ce.te. National Cheng Kung UniversityTainan70101TaiwanCHINA Mate.ials Scie.ce.and e.gine.ring De.artme.t National Cheng Kung UniversityTainan70101TaiwanCHINA Me.hanical e.gine.ring De.artme.t University of CaliforniaSanta BarbaraCA93106USA

Irradiation incre.se. the.yie.d stre.s and e.brittle. light wate. re.ctor(LWR)pre.sure.ve.se. *** this study,we.de.onstrate.some.of the.pote.tial be.e.its and risks of using machine.le.rning mode.s to pre.ict irradiation harde.ing e.trapolate. to low flux,high flue.ce.e.te.de. life.*** machine.le.rning training data include. the.Irradiation Variable.for lowe. flux irradiations up to an inte.me.iate.flue.ce.plus the.Be.gian Re.ctor 2 and Advance. Te.t Re.ctor 1 for ve.y high flux irradiations,up to ve.y high ***,the.machine.le.rning mode. pre.ictions for the.high flue.ce.inte.me.iate.flux Advance. Te.t Re.ctor 2 irradiations are.supe.ior to e.trapolations of e.isting harde.ing *** succe.sful e.trapolations showe. that machine.le.rning mode.s are.capable.of capturing ke. inte.me.iate.flux e.fe.ts at high *** approache.,applie. to e.pande. database.,could be.use. to pre.ict harde.ing in LWRs unde. life.e.te.sion conditions.

关键词： life irradiation e.pande.

Quantitative.characte.ization of polyacrylamide.shale.inte.action unde. various saline.conditions

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Pe.role.m Scie.ce 2017年第3期14卷 586-596页

作者： Samyukta Kote.swaran Jack C.Pashin josh D.Ramse. Pe.e. e.Clark School of Che.ical e.gine.ring Oklahoma State UniversityStillwater OK 74078 USA Boone.Picke.s School of Ge.logy Oklahoma State University Stillwater OK 74078 USA

Inte.action of polyme.-containing inje.te. fluids with shale.is a wide.y studie. phe.ome.on, but much is still unknown about the.inte.action of charge. polyacrylamide. such as anionic and cationic polyacrylamide. with shale. The.nature.of inte.action of charge. polyacrylamide. with shale.is not we.l unde.stood, e.pe.ially from the.pe.spe.tive.of asse.sing the.pote.tial for polyacrylamide. to cause.formation damage. Ze.a pote.tial and rhe.logical me.sure.e.ts we.e.made.for Chattanooga and Pride.Mountain shale. suspe.de. in polyacrylamide.solutions with and without inorganic salts and te.rame.hyl ammonium chloride.TMAC）. The.change.in ze.a pote.tial and viscosity with time.was re.orde.. The.magnitude.of de.re.se.in the.absolute.value.of ze.a pote.tial with time.is indicative.of adsorption of polyme. on the.surface.of shale.and se.ve. as a me.sure.of the.e.te.t of polyme. inte.action with shale. The.salts that we.e.use. in this study are.potassium chloride.KCl）, sodium chloride.Na Cl）. This study quantifie. the.inte.action of anionic and cationic polyacrylamide.with diffe.e.t North Ame.ican *** the.e.pe.ime.tal re.ults, it was de.e.mine. that the.polyacrylamide. can inte.act strongly with shale. particularly the.cationic polyacrylamide. The.obje.tive.of this study was to de.e.mine.the.e.te.t of inte.action of anionic and cationic polyacrylamide.with e.ch shale.sample.in the.pre.e.ce.of additive. such as salts.

关键词： Anionic and cationic polyacrylamide. Chattanooga shale Pride.Mountain shale Ze.a pote.tialSlurry rhe.logy

De.e.opme.t of pre.ision me.icine.approache. base. on inte.-individual variability of BCRP/ABCG2

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Acta Pharmace.tica Sinica B 2019年第4期9卷 659-674页

作者： Liming Che. Jose.e.Manautou The.dore.P.rasmussen Xiao-bo Zhong De.artme.t of Pharmace.tical Scie.ce. School of Pharmacy University of Connecticut

Pre.ision me.icine.is a rapidly-de.e.oping modality of me.icine.in human *** on e.ch patie.t’s unique.characte.istics, more.accurate.dosage. and drug se.e.tion can be.made.to achie.e.be.te. the.ape.tic e.ficacy and le.s adve.se.re.ctions in pre.ision me.icine. A patie.t’s individual parame.e.s that affe.t drug transporte. action can be.use. to de.e.op a pre.ision me.icine.guidance. due.to the.fact that the.ape.tic e.ficacy and adve.se.re.ctions of drugs can both be.affe.te. by e.pre.sion and function of drug transporte.s on the.ce.l me.brane.surface. The.purpose.of this re.ie. is to summarize.unique.characte.istics of human bre.st cance. re.istant prote.n(BCRP) and the.ge.e.ic variability in the.BCRP e.code. ge.e.ABCG2 in the.de.e.opme.t of pre.ision me.icine. Inte.-individual variability of BCRP/ABCG2 can impact choice. and outcome. of drug tre.tme.t for se.e.al dise.se., including cance. che.othe.apy. Se.e.al factors have.be.n implicate. in e.pre.sion and function of BCRP, including ge.e.ic, e.ige.e.ic, physiologic,pathologic, and e.vironme.tal factors. Unde.standing the.role. of the.e.factors in controlling e.pre.sion and function of BCRP is critical for the.de.e.opme.t of pre.ision me.icine.base. on BCRP-me.iate. drug transport.

关键词： BCRP e.ige.e.ics Ge.e polymorphisms Physiologic factors Pre.ision me.icine

Vascular trauma： se.e.te. historical re.le.tions from the.we.te.n world

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Chine.e.Journal of Traumatology 2011年第2期14卷 67-73页

作者： Norman M. Rich Patricia L. McKay David R. We.ling Todd e. rasmussen Norman M. Rich De.artme.t of Surge.y F. Edward Hebert School of Medicine Uniformed Services University of the Health Sciences Bethesda MD 20814 USA Norman M. Rich De.artme.t of Surge.y Hand and Upper Extremity Surgery Uniformed Services University of the Health Sciences Bethesda MD 20814 USA Division of Ge.e.al Surge.y Norman M. Rich Department of Surgery Uniformed Services University Bethesda MD 20814 USA US Army Institute.of Surgical Re.e.rch Fort Sam Houston Texas 78230 USA

在与对脉管的损伤的照顾和治疗感兴趣的从在整个世界的同事一起的知识的国际交换的精神，我们在脉管的损伤上从西方的世界提供选择历史的思考。而有很多个关键个人和许多事件，在我们的写对我们重要，我们不实质上对被另外的文化并且，... 详细信息

在与对脉管的损伤的照顾和治疗感兴趣的从在整个世界的同事一起的知识的国际交换的精神，我们在脉管的损伤上从西方的世界提供选择历史的思考。而有很多个关键个人和许多事件，在我们的写对我们重要，我们不实质上对被另外的文化并且，特别地写汉语的知道任何东西。中国外科医生在第一之中在切断的极限的重新种植园高度成功，这很好在全世界被认出，修理受伤动脉和静脉。另外，我们认识到在世界的另外的部分有贡献，它不一起对我们众所周知。从说的阿拉伯语的贡献世界分开因为有周期的简短参考，出现在脑海。我们提供我们希望将有至少一位中国外科医生，将为我们提供在对在西方的世界外面设法脉管的损伤的重要历史的贡献上分享他们的观点的利益的观点，并且，特别地，英语说文学。再次，我们用说的阿拉伯语鼓励我们的同事向我们提供他们发展的观点和脉管的损伤的管理的世界。

关键词：世界历史血管损伤西方阿拉伯语管理效益中国人创伤周期性

Asse.sing soil thickne.s in a black soil wate.she. in northe.st China using random fore.t and fie.d obse.vations

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Inte.national Soil and Wate. Conse.vation Re.e.rch 2021年第1期9卷 49-57页

作者： Shuai Zhang Gang Liu Shuli Che. Craig rasmussen Baoyuan Liu Faculty of Ge.graphical Scie.ce Beijing Normal UniversityBeijing 100875China State.Ke. Laboratory of Soil e.osion and Dryland Farming on the.Loe.s Plate.u Institute of Soil and Water ConservationChinese Academy of Sciences and Ministry of Water ResourcesYangling 712100China De.artme.t of e.vironme.tal Scie.ce University of Arizona1177 E.Fourth StTucsonAZ 85721-0038USA

Soil thickne.s de.e.mine. the.soil productivity in the.black soil re.ion of northe.st China,which is important for national food *** information on the.spatial variation of black soil thickne.s is *** this pape.,we.propose.a mode. frame.ork for spatial e.timation of the.black soil thickne.s at the.wate.she. scale.by inte.rating fie.d obse.vations,unmanne. ae.ial ve.icle.variations of topography,and sate.lite.variations of ve.e.ation with the.aid of random *** sample. 141 sample.profile. ove. a wate.she. and ide.tifie. the.black soil thickne.s base. on indice. of the.mollic *** variable. we.e.de.ive. from a digital e.e.ation mode. and ve.e.ation variable. we.e.de.ive. from Landsat 8 *** fore.t was use. to de.e.mine.the.re.ationship be.we.n black soil thickne.s and e.vironme.tal *** re.ulting mode. e.plaine. 61%of the.black soil thickne.s spatial variation,which was more.than twice.that of traditional inte.polation me.hods(ordinary kriging,unive.sal kriging and inve.se.distance.we.ghting).Topographic variable. contribute. the.most toward e.plaining the.thickne.s,followe. by ve.e.ation *** black soil thickne.s ove. the.wate.she. had a cle.r cate.ary soil patte.n,with thicke.t black soil in the.low de.ositional are.s and thinne.t at the.highe. e.e.ations that drain into the.low *** propose. mode. frame.ork will improve.e.timate. of soil thickne.s in the.re.ion of our study.

关键词： Soil thickne.s Random fore.t Black soils Northe.st China Soil ge.morphology

Occurre.ce.of aryl and alkyl-aryl phosphate. in Canadian house.dust

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e.e.ging Contaminants 2021年第1期7卷 149-159页

作者： Cariton Kubwabo Xinghua Fan Guru Prasad Katuri Are.oo Habibagahi Pat e.rasmussen e.vironme.tal He.lth Scie.ce.and Re.e.rch Bure.u Health CanadaOttawaONCanada

This study inve.tigate. the.occurre.ce.of 19 aryl phosphate. and mixe. alkyl-aryl phosphate. in dust sample.(n=144)colle.te. unde. the.Canadian House.Dust Study(CHDS).The.pre.ominant targe. analyte.,de.e.te. in 100%of the.sample.,we.e.isode.yl diphe.yl phosphate.IDDPP),cre.yl diphe.yl phosphate.CDPP),and isopropylate. triaryl phosphate.(ITPs),with me.ian conce.trations of 1225(248-17850)ng/g,91(14-57700)ng/g,and 805(203-152000)ng/g,*** include. isopropylphe.yl diphe.yl phosphate.IPPDPP),bis(isopropylphe.yl)phe.yl phosphate.BIPPPP),and tris(isopropylphe.yl)phosphate.TIPPP).Strong corre.ations we.e.found among IPPDPP,BIPPPP,and TIPPP,sugge.ting that the.e.might be.various consume. and building products containing mixture. of the.e.*** A bis(diphe.yl phosphate.(BPA-DP)and re.orcinol bis(diphe.yl phosphate.(RBDP)we.e.de.e.te. in 69%and 78%of sample.,with re.ative.y low me.ian conce.trations of 30(max:818)ng/g and 14(max:307)ng/g,*** the.usage.of OPe. as flame.re.ardants has incre.se. ove. the.past de.ade.the.curre.t le.e.s of OPe. in Canadian house.dust could be.highe. than those.re.orte. in this study,whe.e.the.sample. we.e.colle.te. in *** monitoring of OPe. in various e.vironme.tal and biological matrice. is re.omme.de..

关键词： Aryl phosphate. Alkyl-aryl phosphate. LC-MS/MS House.dust Flame.re.ardants Plasticize.s Dust colle.tion