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Unveiling the brain’s symphony:exploring the necessity and sufficiency of neural networks in behavior control

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Neural Regeneration Research 2025年第1期20卷 186-187页

作者： Fernando jose Bustos Instituto de Ciencias Biomedicas Facultad de Medicina y Facultad de Ciencias de la VidaUniversidad Andres BelloSantiagoChile Millennium Nucleus of Neuroepigenetics and Plasticity(EpiNeuro) SantiagoChile

since the pioneering work by Broca and Wernicke in the 19th century,who examined individuals with brain lesions to associate them with specific behaviors,it was evident that behaviors are complex and cannot be fully attributable to specific brain areas ***,they involve connectivity among brain areas,whether close or *** that time,this approach was considered the optimal way to dissect brain circuitry and *** pioneering efforts opened the field to explore the necessity or sufficiency of brain areas in controlling behavior and hence dissecting brain ***,the connectivity of the brain and the mechanisms through which various brain regions regulate specific behaviors,either individually or collaboratively,remain largely *** animal models,researchers have endeavored to unravel the necessity or sufficiency of specific brain areas in influencing behavior;however,no clear associations have been firmly established.

关键词： behavior connectivity neural

Implicit Continuous User Authentication for Mobile Devices based on Deep Reinforcement Learning

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Computer systems science & Engineering 2023年第2期44卷 1357-1372页

作者： Christy James jose M.s.Rajasree Government Engineering College Idukki685603India APJ Abdul Kalam Technological University Thiruvananthapuram695016India

The predominant method for smart phone accessing is conﬁned to methods directing the authentication by means of Point-of-Entry that heavily depend on physiological biometrics like,ﬁngerprint or *** continuous authentication initiating to be loftier to conventional authentication mechanisms by continuously conﬁrming users’identities on continuing basis and mark the instant at which an illegitimate hacker grasps dominance of the ***,divergent issues remain *** research aims to investigate the power of Deep Reinforcement Learning technique to implicit continuous authentication for mobile devices using a method called,Gaussian Weighted Cauchy Kriging-based Continuous Czekanowski’s(GWCK-CC).First,a Gaussian Weighted Non-local Mean Filter Preprocessing model is applied for reducing the noise pre-sent in the raw input face *** Kriging Regression function is employed to reduce the ***,Continuous Czekanowski’s Clas-siﬁcation is utilized for proﬁcient classiﬁcation between the genuine user and *** this way,the proposed GWCK-CC method achieves accurate authen-tication with minimum error rate and *** assessment of the pro-posed GWCK-CC method and existing methods are carried out with different factors by using UMDAA-02 Face *** results conﬁrm that the proposed GWCK-CC method enhances authentication accuracy,by 9%,reduces the authen-tication time,and error rate by 44%,and 43%as compared to the existing methods.

关键词： Deep reinforcement learning gaussian weighted non-local meanﬁlter cauchy kriging regression continuous czekanowski’s implicit continuous authentication mobile devices

Different culture conditions applied to in vitro shoot multiplication of two Eucalyptus benthamii explant sources

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Journal of Forestry Research 2020年第3期31卷 857-869页

作者： Natalia Pimentel Esposito-Polesi Leandro silva de Oliveira Francisco jose Benedini Baccarin Cristina vieira de Almeida Marcilio de Almeida Biological science Department "Luiz de Queiroz"Superior College of AgricultureUniversity of Sao Paulo(ESALQ/USP)Padua Dias Avenue11P.O.Box 9PiracicabaSP 13418-900Brazil Institute of Agriculture sciences Federal University of Minas Gerais(UFMG)Universitaria Avenue1000Montes ClarosMG 39404-547Brazil state University of Goias(UEG) Rua S7Qd.1S SulPalmeiras de GoiasGO 76190-000Brazil In vitro Palm Consultoria Estudo e Desenvolvimento Biologico LtdaRua Itajobi421PiracicabaSP 13432-000Brazil

Eucalyptus adult material requires more successive subcultures in the in vitro multiplication phase for increased vigor and cellular activity. This study evaluated the endophytic manifestation and shoot multiplication of one 13-year-old Eucalyptus benthamii clone under different culture conditions and used canopy branches(CB) and trunk base material as explant sources. The culture media were wood plant medium(WPM), Murashige and skoog medium(Ms) and JADs(Correia and co-authors medium).Based on the results of the initial multiplication experiment, further tests examined sucrose concentrations and p H. Morphophysiology, dry mass production, endophyticmanifestation and histochemical were determined. Explant sources responded differently to Ms and JADs media, but the WPM medium promoted homogeneous *** responses were similar for both explant sources when sucrose concentrations varied. shoots died in the absence of sucrose, showed high oxidation at 60 g L-1 and optimal development at 30 g L-1. Endophytes were more evident for shoots from the CB origin. Explant sources responded distinctively to treatment due to physiological and intrinsic genetic factors. Therefore, explant sources, different culture media, sucrose concentration and p H may determine micropropagation success and influence the presence and/or intensity of endophytic manifestation.

关键词： Plant tissue culture Explant sources Culture media sucrose pH

Global changes explain the long-term demographic trend of the Eurasian common lizard (squamata: Lacertidae)

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Current Zoology 2022年第2期68卷 221-228页

作者： jose L.HORREO Patrick s.FITZE Department of Genetics Physiology and MicrobiologyComplutense University of MadridC/Jose Antonio Novais 12Madrid 28040Spain Department of Biodiversity and Evolutionary Biology National Museum of Natural Sciences(CSIC)C/Jose Gutierrez Abascal 2Madrid 28006Spain

The demographic trend of a species depends on the dynamics of its local populations,which can be compromised by local or by global ***,the relevance of local and global phenomena has rarely been investigated ***,we tested whether local phenomena compromised a species'demographic trend using the Eurasian common lizard Zootoca vivipara,the terrestrial reptile exhibiting the widest geographic distribution,as a model *** analyzed the species'ancient demographic trend using genetic data from its 6 allopatric genetic clades and tested whether its demographic trend mainly depended on single clades or on global *** vivipara's effective population size increased since 2.3 million years ago and started to increase steeply and continuously from 0.531 million years *** growth rate exhibited 2 maxima,both occurring during global climatic changes and important vegetation changes on the northern *** population size and growth rate were negatively correlated with global surface temperatures,in line with global parameters driving long-term demographic *** vivipara's ancient demography was neither driven by a single clade,nor by the 2 clades that colonized huge geographic areas after the last *** low importance of local phenomena,suggests that the experimentally demonstrated high sensitivity of this species to short-term ecological changes is a response in order to cope with short-term and local *** suggests that what affected its long-term demographic trend the most,were not these local changes/responses,but rather the important and prolonged global climatic changes and important vegetation changes on the northern hemisphere,including the opening up of the forest by humans.

关键词： ancient demographic trend anthropological activity Bayesian skyline Plots early humans Eemian interglacial Eurasian common lizard mid-Brunhes event

Tuna classification using super learner ensemble of region-based CNN-grouped 2D-LBP models

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Information Processing in Agriculture 2022年第1期9卷 68-79页

作者： Jisha Anu jose C.sathish Kumar s.sureshkumar Rajiv Gandhi Institute of Technology KottayamIndia Government Engineering College IdukkiIndia Kerala University of Fisheries and Ocean studies KochiIndia

Tuna is superior among the marine fishes that are exported in the forms of raw fish and processed *** of Tuna into their species is done in industries manually,and the process is *** work proposes an automated system for classifying Tuna spe-cies based on their *** ensemble of region-based deep neural networks is used.A sub region contrast stretching operation is applied to enhance the *** fish image is then divided into three regions and is augmented before giving as input to pre-trained convolutional neural networks(CNN).After fine-tuning the models,the output from the last convolutional layer is given to a grouped 2D-local binary pattern descriptor(G2DLBP).statistical features from the descriptor are applied to different classifiers,and the best clas-sifier for each image region model is *** ensemble methods are subse-quently used to combine the three CNN-G2DLBP *** the ensemble techniques,super learner ensemble method with random forest(RF)classifier using 5-fold cross-validation shows the highest classification accuracy of 97.32%.The perfor-mance of different ensemble methods is analyzed in terms of accuracy,precision,recall,and *** proposed system shows an accuracy of 93.91% when evaluated with an independent test *** ensemble of region-based CNN with textural features from G2DLBP is applied for the first time for fish classification.

关键词： Tuna classification Convolutional neural network Grouped 2D-local binary pattern super learner ensemble

Real-world data on the infliximab biosimilar CT-P13 (Remsima®) in inflammatory bowel disease

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World Journal of Clinical Cases 2021年第36期9卷 11285-11299页

作者： jose María Huguet Xavier Cortés Marta Maia Bosca-Watts Marian Aguas Nuria Maroto Lidia Martí Cirilo Amorós jose María Paredes Department of Gastroenterology General University Hospital of ValenciaValencia 46014Spain Department of Gastroenterology Hospital de SaguntoSagunto 46520Spain Department of Gastroenterology Hospital Clinico Universitario de ValenciaValencia 46010Spain Department of Gastroenterology Hospital Universitario y Politecnico la Fe de ValenciaValencia 46026Spain Department of Gastroenterology Hospital de ManisesManises 46940Spain Department of Gastroenterology Hospital Comarcal Francesc de BorjaGandia 46702Spain Department of Gastroenterology Hospital Arnau de Vilanova de ValenciaValencia 46015Spain Department of Gastroenterology Hospital Universitario Doctor Peset de ValenciaValencia 46017Spain

BACKGROUND In recent years,biological therapies have revolutionized the management of inflammatory bowel disease(IBD);however,they are *** development of biosimilar products has allowed us to reduce healthcare costs and improve patients’access to these *** various studies support the similarity between infliximab and its biosimilar CT-P13 in terms of efficacy and safety,there are unmet needs regarding research on these agents in the context of *** To analyze clinical response rates to CT-P13 and adverse events in IBD patients treated in real-life *** An observational,prospective,multicenter study of IBD patients treated with CTP13 in clinical practice who were naïve to biological treatments or failed to respond to other anti-tumor necrosis factor drugs or had switched from infliximab originator was carried *** diagnostic or follow-up interventions were conducted on patients outside usual clinical *** primary endpoints were clinical response rates and number of adverse *** primary efficacy variable was the proportion of patients who were in clinical remission and/or had a clinical response at 3,6,9,and 12 *** A total of 220 IBD patients treated with CT-P13(Remsima®)were included in the study:87(40%)with ulcerative colitis and 133(60%)with Crohn’s *** age of the patients was 41.47(sD 15.74)years,and 58%were ***(9%)patients started treatment with CT-P13 after switching from *** the remaining 201 patients,142(65%)were naïve to biologic *** baseline,68.6%(n=138/201)of patients presented with active *** 12 mo of treatment,14.8%(n=12/81)presented with active disease,and 64.2%(n=52/81)were in clinical remission without *** 3 mo,75.5%(n=115/152)had a clinical response or achieved clinical remission,which was sustained for 12 mo(85.2%;n=69/81).There was a decrease in specific IBD indices at 3,6,9,and 12 mo(Pse events

关键词： Crohn’s disease Ulcerative colitis Inflammatory bowel disease Infliximab Biosimilar CT-P13

Enzymatic Conversion of sugarcane Lignocellulosic Biomass as a Platform for the Production of Ethanol,Enzymes and Nanocellulose

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Journal of Renewable Materials 2018年第2期6卷 203-216页

作者： Cristiane s.Farinas jose Manoel Marconcini Luiz Henrique C.Mattoso Nanotechnology National Laboratory for Agriculture(LNNA) Embrapa InstrumentationRua XV de Novembro 145213561-206São CarlosSPBrazil

The conversion of sugarcane lignocellulosic biomass into fuels,chemicals and high-value materials using the biochemical pathway is considered the most sustainable alternative for the implementation of future ***,the first large-scale cellulosic ethanol plants that have started operating worldwide apply the enzymatic hydrolysis process to convert biomass into simple sugars that are fermented to ethanol by ***,several technological challenges still need to be addressed in order to obtain commercially competitive *** review describes current challenges and perspectives regarding the enzymatic hydrolysis step for processing sugarcane lignocellulosic biomass within the *** developments in terms of process configuration strategies and opportunities for the implementation of a sugarcane biorefinery,in which the production of ethanol is integrated into the production of high-value products such as enzymes and nanocellulose,are discussed in view of the demands of the current bioeconomy.

关键词： Enzymatic hydrolysis bioethanol sugarcane nanocellulose biorefinery

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Microwave photonics

science China(Information sciences) 2022年第12期65卷 49-112页

作者： Jianping YAO jose CAPMANY Microwave Photonics Research Laboratory School of Electrical Engineering and Computer Science University of Ottawa ITEAM Research Institute Universitat Politècnica de València iPronics Programmable Photonics

Microwave photonics, an interdisciplinary field that combines microwave engineering and photonic technology for the generation, transmission, processing, and control of microwave signals, to take advantage of the broad bandwidth, high frequency, and low loss offered by modern photonics, has been intensively researched for the last few decades, and numerous solutions have been proposed and demonstrated. In this article, an overview about microwave photonics is provided which covers the basic concepts of microwave photonics, photonic-assisted microwave signal generation, photonic-assisted microwave signal processing, and true time delay beamforming. The implementation of microwave photonic systems based on photonic integrated circuits is also reviewed, including the design, fabrication, and material platforms, application-specific photonic integrated circuits for microwave photonics, and programmable integrated microwave *** challenges and future applications of microwave photonics are also discussed.

关键词： microwave photonics photonic integrated circuits microwave photonic link microwave photonic signal processor optoelectronic oscillator radio over fiber

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single-shot incoherent optical processing of microwave signals： opening the path to low cost high performance analog photonics

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science Bulletin 2017年第9期62卷 652-653页

作者： jose Capmany ITEAM Research Institute Universitat Politecnica de Valencia Camino de Vera s/n 46022 Valencia Spain

Incoherent optical processing of microwave signals,where low-coherence broadband light sources are employed instead of costly mode locked lasers,has attracted great interest thanks to its wide applications in microwav... 详细信息

关键词： single-shot incoherent optical processing of microwave signals:opening the path to low cost high performance analog photonics high MZM sNR mode sLD